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| | pmd1 | Transport ATP-binding protein; MPN018(new), 136(Himmelreich et al., 1996). (623 aa) |
| | msbA | Transport ATP-binding protein; MPN019(new), 135(Himmelreich et al., 1996). (634 aa) |
| | glpF | Glycerol uptake facilitator; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane (By similarity). (264 aa) |
| | glpD | Glycerol-3-phospate dehydrogenase; MPN051(new), 103(Himmelreich et al., 1996). (384 aa) |
| | D09_orf657 | Putative lipoprotein; MPN052(new), 102(Himmelreich et al., 1996). (657 aa) |
| | potA | Spermidine/putrescine transport ATP-binding prot; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (560 aa) |
| | potB | Spermidine/putrescine transport system permease; Required for the activity of the bacterial transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (286 aa) |
| | secE | SecE; MPN068(new), 086(Himmelreich et al., 1996). (125 aa) |
| | R02_orf1386V | Probably ABC transporter membrane protein subunit; MPN080(new), 075(Himmelreich et al., 1996). (1386 aa) |
| | glnQ | Glutamine transport ATP-binding protein; MPN081(new), 074(Himmelreich et al., 1996); Belongs to the ABC transporter superfamily. (465 aa) |
| | tklB | Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate; Belongs to the transketolase family. (648 aa) |
| | R02_orf254 | Amino acid permease; MPN095(new), 060(Himmelreich et al., 1996); see: MPN096. (254 aa) |
| | R02_orf264 | Amino acid permease; MPN096(new), 059(Himmelreich et al., 1996). (264 aa) |
| | MPN_113 | G3P transporter-like protein; MPN113(new), 042(Himmelreich et al., 1996). (223 aa) |
| | parC | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily. (789 aa) |
| | ugpC | Sn-glycerol-3-phosphate transport system permease protein; MPN134(new), 021(Himmelreich et al., 1996); Belongs to the ABC transporter superfamily. (586 aa) |
| | ugpA | Sn-glycerol-3-phosphate transport system permease protein; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily. (329 aa) |
| | ugpE | Sn-glycerol-3-phosphate transport system permease protein; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily. (319 aa) |
| | P1 | Adhesin P1; The protein is the major adhesin mediating the attachment of this mycoplasma to respiratory epithelium. (1627 aa) |
| | hlyC | TlyC-like protein; MPN159(new), 673(Himmelreich et al., 1996). (424 aa) |
| | secY | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (477 aa) |
| | cysA | Cobalt transport ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (274 aa) |
| | hisP | Cobalt transport ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (303 aa) |
| | GT9_orf434 | Cobalt transport membrane protein-like protein; MPN195(new), 637(Himmelreich et al., 1996). (434 aa) |
| | ptsG | PTS system, glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. (940 aa) |
| | mgtA | Cation-transporting P-type ATPase; Could mediate calcium influx. (872 aa) |
| | secA | Preprotein translocase SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (808 aa) |
| | oppB | Oligopeptide transport system permease protein OppB; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (389 aa) |
| | oppD | Oligopeptide transport ATP-binding protein OppD; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system (By similarity); Belongs to the ABC transporter superfamily. (423 aa) |
| | oppF | OppF; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system (By similarity); Belongs to the ABC transporter superfamily. (851 aa) |
| | lgt | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (389 aa) |
| | K04_orf222 | Conserved hypothetical protein; MPN239(new), 593(Himmelreich et al., 1996). (222 aa) |
| | secG | SecG; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. (76 aa) |
| | dacB | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria; Belongs to the adenylate cyclase family. DacB/CdaS subfamily. (202 aa) |
| | ptc1 | Protein phoshatase 2C-like protein; MPN247(new), 586(Himmelreich et al., 1996); similar to Swiss-Prot Accession Number P35182. (259 aa) |
| | pgsA | Phosphatidylglycerophosphate synthase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (227 aa) |
| | yjcW | Sugar (ribose/galactose) ABC transporter ATP-binding subunit; Part of the ABC transporter complex involved in carbohydrates import. Probably responsible for energy coupling to the transport system (By similarity). (572 aa) |
| | A65_orf517 | Sugar (ribose/galactose) ABC transporter permease subunit, but probably C-terminal; MPN259(new), 575(Himmelreich et al., 1996). (517 aa) |
| | A65_orf117 | Hypothetical protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (117 aa) |
| | lepA | GTP-binding membrane protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (581 aa) |
| | lsp | Prolipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (184 aa) |
| | plsB | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (266 aa) |
| | pyk | Pyruvate kinase; MPN303(new), 534(Himmelreich et al., 1996). (508 aa) |
| | F10_orf565 | Amino acid permease; MPN308(new), 529(Himmelreich et al., 1996); see: MPN096. (565 aa) |
| | F10_orf357 | Conserved hypothetical protein; MPN311(new), 526(Himmelreich et al., 1996). (357 aa) |
| | F10_orf491 | Amino acid permease; MPN318(new), 519(Himmelreich et al., 1996). (491 aa) |
| | gap1 | General amino acid permease GAP1-like protein; MPN319(new), 518(Himmelreich et al., 1996); similar to Swiss-Prot Accession Number P19145. (503 aa) |
| | F10_orf750 | Hypothetical protein; MPN333(new), 504(Himmelreich et al., 1996). (750 aa) |
| | F10_orf741 | Hypothetical protein; MPN335(new), 502(Himmelreich et al., 1996). (741 aa) |
| | ygiH | Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (239 aa) |
| | yaaF | Deoxyguanosine kinase/deoxyadenosine kinase; MPN386(new), 452(Himmelreich et al., 1996). (229 aa) |
| | pdhD | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes. (457 aa) |
| | pdhC | Dihydrolipoamide acetyltransferase component (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (402 aa) |
| | pdhB | Pyruvate dehydrogenase E1-beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (327 aa) |
| | pdhA | Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (358 aa) |
| | P37 | High affinity transport system protein P37; P37 is part of a high-affinity transport system. (380 aa) |
| | P29 | ATP-binding protein P29; Part of a high-affinity transport system. (244 aa) |
| | P69 | Transport system permease protein P69; Probably part of a high-affinity transport system. (542 aa) |
| | A05_orf475 | Permease; MPN421(new), 419(Himmelreich et al., 1996); To E.coli YihN. (475 aa) |
| | ftsY | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (348 aa) |
| | gap | Glycerladehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG; Belongs to the glyceraldehyde-3-phosphate dehydrogenase [...] (337 aa) |
| | A05_orf317 | Permease; MPN431(new), 409(Himmelreich et al., 1996). (317 aa) |
| | artP | Abc transport ATP-binding protein; MPN432(new), 408(Himmelreich et al., 1996); Belongs to the ABC transporter superfamily. (382 aa) |
| | cbiO | Abc transport ATP-binding protein; MPN433(new), 407(Himmelreich et al., 1996); Belongs to the ABC transporter superfamily. (270 aa) |
| | A05_orf395 | Permease; MPN435(new), 405(Himmelreich et al., 1996). (395 aa) |
| | MPN_439 | Mollicute specific lipoprotein; MPN439(new), 401(Himmelreich et al., 1996); see: MPN436. (237 aa) |
| | MPN_442 | Species specific lipoprotein; MPN442(new), 398(Himmelreich et al., 1996). (150 aa) |
| | hmw1 | Cytadherence accessory protein HMW1; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle (By similarity). (1018 aa) |
| | come3 | Competence locus operon protein 3-like protein; MPN451(new), 389(Himmelreich et al., 1996); similar to Swiss-Prot Accession Number P39695. (369 aa) |
| | hmw3 | Cytadherence accessory protein HMW3; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle. Essential for successful surface parasitism. (672 aa) |
| | p30 | 30K adhesin-related protein; Adhesin necessary for successful cytadherence and virulence. (274 aa) |
| | ntpJ | KtrB; MPN460(new), 380(Himmelreich et al., 1996). (565 aa) |
| | yzaC | KtrA, K+ Na+ uptake; MPN461(new), 379(Himmelreich et al., 1996). (231 aa) |
| | MPN_482 | Conserved hypothetical protein; MPN482(new). (64 aa) |
| | yjfS | Phosphotransferase protein-like protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport. Belongs to the UlaA family. (660 aa) |
| | spg | Small GTPase ERA involved in regulating metabolism and cell division; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (291 aa) |
| | LcnDR3 | Hemolysin ABC-type exporter-like protein; MPN571(new), 271(Himmelreich et al., 1996). (660 aa) |
| | atpC | ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. (133 aa) |
| | atpD | ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (475 aa) |
| | atpG | ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (279 aa) |
| | atpA | ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (518 aa) |
| | atpH | ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (178 aa) |
| | atpF | ATP synthase B chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (207 aa) |
| | atpE | ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (105 aa) |
| | atpB | ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (293 aa) |
| | pstB | Phosphate specific; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (329 aa) |
| | pstA | Psta /Pstc-like ABC transporter; Could be part of a binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (651 aa) |
| | pgm | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (508 aa) |
| | cdsA | CDP-diglyceride synthetase; MPN637(new), 205(Himmelreich et al., 1996). (395 aa) |
| | mtlA | Mannitol-specific PRS EIIBC-like protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (379 aa) |
| | mtlF | PTS system mannitol-specific component IIA; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (143 aa) |
| | K05_orf499 | Conserved hypothetical protein; MPN661(new), 181(Himmelreich et al., 1996). (549 aa) |
| | tuf | Elongation factor TU; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (394 aa) |
| | gtaB | UDP-glucose pyrophosphorylase; May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. (291 aa) |
| | ftsH | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. (709 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (312 aa) |
| | yidC | Conserved hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity). (385 aa) |
| | devA | ABC transporter subunit; MPN683(new), 159(Himmelreich et al., 1996); Belongs to the ABC transporter superfamily. (339 aa) |
| | K05_orf1882 | Conserved hypothetical protein; MPN684(new), 158(Himmelreich et al., 1996); possible membrane transporter component. (1882 aa) |
| | cysA-2 | Sulfate transport ATP-binding protein; MPN685(new), 157(Himmelreich et al., 1996); Belongs to the ABC transporter superfamily. (284 aa) |
