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| | rps15P | rps15P SSU ribosomal protein S15P. (158 aa) |
| | rps3AE | rps3AE SSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (200 aa) |
| | rad25-like | DNA/RNA repair helicase. (446 aa) |
| | PAB0161 | Hypothetical protein, containing archaeal Zn-finger. (204 aa) |
| | PAB0172 | Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase. (210 aa) |
| | PAB0176 | Protein involved in ribosomal biogenesis. (166 aa) |
| | fus | Fus translation elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTP [...] (732 aa) |
| | thii | thiI thiamin biosynthesis protein thiI. (198 aa) |
| | PAB0282 | Hypothetical protein. (204 aa) |
| | pimT-like | SAM-dependent methyltransferase, putative; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenosine at position(s) 57 (m1A57) and 58 (m1A58) in the T- loop of some tRNAs. Methylates the first adenine of an AA sequence. Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family. (253 aa) |
| | PAB0284 | Predicted rRNA or tRNA methylase. (197 aa) |
| | dnaG | Primase dnaG-like; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (447 aa) |
| | srp54 | Srp54 signal recognition particle, subunit SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (443 aa) |
| | gltX | gltX glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa) |
| | PAB0339 | Predicted Zn-dependent hydrolase of the beta-lactamase fold; Belongs to the UPF0173 family. (225 aa) |
| | trub | truB tRNA pseudouridine synthase II; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (334 aa) |
| | PAB0359 | Ribosomal RNA small subunit methyltransferase C (rRNA (guanine-n2-)-methyltransferase) (16S rRNA M2G1207 methyltransferase). (195 aa) |
| | rps13P | rps13P SSU ribosomal protein S13P/S18E; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (148 aa) |
| | rps4P | rps4P SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa) |
| | rps11P | rps11P SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (137 aa) |
| | rpl18E | rpl18E LSU ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa) |
| | rpl13P | rpl13P LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | rps9P | rps9P SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (135 aa) |
| | rps2P | rps2P SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (202 aa) |
| | glyS | glyS glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (571 aa) |
| | PAB0384 | Predicted ATPase involved in replication control, Cdc46/MCM familyn. (491 aa) |
| | rnp4 | RNAse P protein subunit RPR2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (117 aa) |
| | prf1 | Prf1 peptide chain release factor subunit 1 (translation termination factor ARF1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (417 aa) |
| | PAB0405 | Predicted serine/threonine protein kinase, rio1 family. (266 aa) |
| | PAB0406 | Predicted RNA-binding protein. (221 aa) |
| | PAB0415 | Predicted ATPases of PP-loop superfamily. (210 aa) |
| | psmA | psmA proteasome, subunit alpha (EC 3.4.99.46); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (260 aa) |
| | PAB0418 | Hypothetical protein; Belongs to the SDO1/SBDS family. (236 aa) |
| | rrp4 | Predicted exosome subunit, RNA-binding protein rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (265 aa) |
| | rph | Rph ribonuclease PH, exosome complex exonuclease; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails (Probable). (249 aa) |
| | rrp42 | RNAse PH-related exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (274 aa) |
| | rpoB | rpoB DNA-directed RNA polymerase, subunit B (EC 2.7.7.6); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1117 aa) |
| | rpoA1 | rpoA1 DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (907 aa) |
| | rpoA2 | rpoA2 DNA-directed RNA polymerase, subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (397 aa) |
| | nusA | nusA transcription termination-antitermination factor nusA, putative; Participates in transcription termination. Belongs to the NusA family. (145 aa) |
| | rps12P | rps12P SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa) |
| | rps7P | rps7P SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (215 aa) |
| | truD | Hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (406 aa) |
| | PAB0433 | Hypothetical protein. (115 aa) |
| | rpl7AE | rpl7AE LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (128 aa) |
| | tuf | Tuf translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (428 aa) |
| | rps10P | rps10P SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | rnp2 | RNAse P subunit P14 ortholog; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (119 aa) |
| | pelA | pelA cell division protein pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (356 aa) |
| | argS | argS arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (625 aa) |
| | trxB | trxB thioredoxin reductase. (345 aa) |
| | dys1 | Dhs deoxyhypusine synthase (EC 2.5.1.46); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. (335 aa) |
| | obg-like | GTP-binding protein, putative. (357 aa) |
| | thiI-like | thiI-like thiamin biosynthesis protein. (306 aa) |
| | aif2A | eIF2A translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family. (275 aa) |
| | rpl15E | rpl15E LSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (194 aa) |
| | PAB0591 | Putative DEAH ATP-dependent helicase. (973 aa) |
| | ileS | ileS isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1067 aa) |
| | PAB0620 | Hypothetical protein; Belongs to the PDCD5 family. (115 aa) |
| | rpl21E | rpl21E LSU ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa) |
| | PAB0732 | rpoF DNA-directed RNA polymerase, subunit F. (121 aa) |
| | adkE | adkE adenylate kinase (adk) (EC 2.7.4.3); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (220 aa) |
| | PAB0746 | Putative diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. (339 aa) |
| | rps8E | rps8E SSU ribosomal protein S8E. (127 aa) |
| | infB | infB intein containing translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). (992 aa) |
| | cmk | Cmk cytidylate kinase. (181 aa) |
| | PAB0764 | Histone deacetylase. (334 aa) |
| | PAB0824 | ABC transporter ATP-binding protein. (593 aa) |
| | PAB0825 | Translation initiation inhibitor; Belongs to the RutC family. (127 aa) |
| | serS | serS seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (455 aa) |
| | nob1 | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family. (161 aa) |
| | cysS | cysS cysteinyl-tRNA synthetase. (477 aa) |
| | tfe | Probable archaeal transcription factor, related to transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing [...] (190 aa) |
| | eif2b | Translation initiation factor eIF-2, beta subunit, putative; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family. (140 aa) |
| | eif-6 | Ribosome anti-association factor eIF6 homolog; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (227 aa) |
| | PAB1013 | Predicted serine/threonine protein kinase, RIO-like. (313 aa) |
| | PAB1045 | Hypothetical protein. (122 aa) |
| | PAB1046 | Uncharacterized ArCR. (379 aa) |
| | hisS | hisS histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa) |
| | rpoE1 | rpoE1 DNA-directed RNA polymerase, subunit E'. (188 aa) |
| | trpS | trpS tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (385 aa) |
| | rnp3 | Ribonuclease P subunit rpp30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (212 aa) |
| | rpl1 | LSU ribosomal protein L1P (rpl1P); Binds directly to 23S rRNA. Probably involved in E site tRNA release. (219 aa) |
| | rpl10 | rpl10E LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (341 aa) |
| | rpl12 | rpl12A LSU ribosomal protein L12A; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (107 aa) |
| | rpl44e | rpl44E LSU ribosomal protein L44E; Binds to the 23S rRNA. (94 aa) |
| | valS | valS valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (891 aa) |
| | PAB1312 | ERCC3/XPB TFIIH basal transcription factor complex helicase, XPB subunit homolog. (453 aa) |
| | lon | Lon intein containing ATP-dependent protease La homolog; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Degrades polypeptides processively (By similarity); Belongs to the peptidase S16 family. Archaeal LonB subfamily. (998 aa) |
| | PAB1357 | GTP-binding protein. (397 aa) |
| | rps6e | rps6E SSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. (125 aa) |
| | map | Map methionine aminopeptidase (EC 3.4.11.18); Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (295 aa) |
| | rpl10e | rpl10E ribosomal protein L10; Belongs to the universal ribosomal protein uL16 family. (181 aa) |
| | PAB1464 | Tfs archaeal transcription factor S; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (110 aa) |
| | ndk | Ndk nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (162 aa) |
| | thrS | thrS threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) (Probable). Edits incorrectly charged L-seryl-tRNA(Thr) via its editing domain. Deacylates correctly charged glycyl-tRNA(Gly), but neither glycyl-tRNA(Gly)(2'-dA76) (the terminal 2'-OH of tRNA(Thr) adenine 76 has been replaced by hydrogen) nor the 2'-fluoro tRNA derivative do so, strongly suggesting the editing function is tRNA catalyzed. Belongs to the class-II aminoacyl-tR [...] (625 aa) |
| | dphB | Dph5 diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. (262 aa) |
| | PAB1540 | Hypothetical protein, containing potential zinc-binding domain; Belongs to the UPF0148 family. (105 aa) |
| | PAB1561 | DNA helicase, putative. (653 aa) |
| | PAB1673 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (216 aa) |
| | truA | truA pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (263 aa) |
| | PAB1716 | Hypothetical protein. (383 aa) |
| | proS | proS prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa) |
| | tbp | TATA box binding protein TFIIB-BBRE complex, chain A; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity). (191 aa) |
| | tyrS | tyrS tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (375 aa) |
| | leuS | leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (967 aa) |
| | rps19e | rps19E SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (150 aa) |
| | nep1 | Hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA (By similarity). (232 aa) |
| | eif5a | Translation initiation factor eIF5A (hypusine containing); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (138 aa) |
| | psmB2 | psmB-like proteasome, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (207 aa) |
| | tfb | TATA box binding protein TFIIB-BBRE complex, chain B; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (300 aa) |
| | PAB1919 | Transcription regulator protein, putative, Mov34/MPN/PAD-1 family. (142 aa) |
| | dpa | GTP-binding signal recognition particle receptor (SRP alpha, SRP54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (322 aa) |
| | PAB2026 | GTP-binding protein. (387 aa) |
| | eif2g | eIF2G translation initiation factor eIF-2, subunit gamma (eIF2G); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (411 aa) |
| | srp19 | Srp19 signal recognition particle, subunit SRP19, putative; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (99 aa) |
| | hsp20 | Hsp20 small heat shock protein; Belongs to the small heat shock protein (HSP20) family. (165 aa) |
| | trm1 | TRM1 N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (383 aa) |
| | PAB2107 | TBP-interacting protein, TIP49 homolog. (441 aa) |
| | PAB2116 | Metal-dependent phosphohydrolase, puative, containing HD region. (417 aa) |
| | PAB2117 | Hypothetical protein. (137 aa) |
| | rpl3 | rpl3P LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (361 aa) |
| | rpl4 | rpl4P LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (255 aa) |
| | rpl2 | rpl2P LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (239 aa) |
| | rps19 | rps19P SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (132 aa) |
| | rps3 | rps3P SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (210 aa) |
| | rnp1 | RNAse P protein subunit P29/POP4; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (127 aa) |
| | rps17 | rps17P SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (116 aa) |
| | rpl24 | rpl24P LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (121 aa) |
| | rpl5 | rpl5P LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (188 aa) |
| | rps8 | rps8E SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpl6 | rpl6P LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (184 aa) |
| | rpl32e | rpl32E LSU ribosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (130 aa) |
| | rpl19e | rpl19E LSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (151 aa) |
| | rpl18 | rpl18P LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (203 aa) |
| | rps5 | rps5P SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (236 aa) |
| | rpl30 | rpl30P LSU ribosomal protein L30P. (155 aa) |
| | rpl15 | rpl15P LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (147 aa) |
| | secY | secY protein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (468 aa) |
| | adkA | adkA archaeal adenylate kinase (EC 2.7.4.3) (ATP-AMP transphosphorylase); Belongs to the archaeal adenylate kinase family. (196 aa) |
| | PAB2141 | Membrane protein, putative. (175 aa) |
| | psmB1 | psmB proteasome, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (197 aa) |
| | asnS | asnS asparaginyl-tRNA synthetase (EC 6.1.1.22) (asparagine--tRNA ligase) (ASNRS); Belongs to the class-II aminoacyl-tRNA synthetase family. (434 aa) |
| | pan | 26S protease regulatory subunit 4; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] (399 aa) |
| | PAB2245 | Glutaredoxin-like protein. (226 aa) |
| | PAB2305 | Nop58p-like pre mRNA splicing protein. (404 aa) |
| | flpA | Fibrillarin pre-rRNA splicing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (227 aa) |
| | csl4 | RNA-binding protein, putative, containing S1 RNA binding domain; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (199 aa) |
| | rpoL | rpoL DNA-directed RNA polymerase, subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (95 aa) |
| | ths | Thermosome subunit (chaperonin subunit); Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family. (550 aa) |
| | nusG | nusG transcription antitermination protein; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (152 aa) |
| | rpl11 | rpl11P LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (164 aa) |
| | asnS-like | asnS-like asparaginyl-tRNA synthetase related protein. (294 aa) |
| | PAB2357 | Component of the U3 small nucleolar ribonucleoprotein, imp4 homolog; Probably involved in the biogenesis of the ribosome. (224 aa) |
| | metS | metS methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (722 aa) |
| | PAB2385 | ERCC2/XPD/rad3 DNA repair helicase, TFIIH helicase beta subunit homolog. (637 aa) |
| | PAB2390 | Sun/NOL1/NOP nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (450 aa) |
| | pus10 | Hypothetical protein, containing THUMP domain; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (393 aa) |
| | rpl22 | rpl22P LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (155 aa) |
| | rps4e | rps4E SSU ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (243 aa) |
| | glpk | glpK glycerol kinase (EC 2.7.1.30); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (494 aa) |
| | rpoD | rpoD DNA-directed RNA polymerase, subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. (259 aa) |
| | pheS | pheS phenylalanyl-tRNA synthetase, subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (500 aa) |
| | pheT | pheT phenylalanyl-tRNA synthetase, subunit beta. (556 aa) |
| | tmcA | Acetyltransferase (GNAT) family, containing ATP/GTP-binding site motif A; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (817 aa) |
| | rpl14 | rpl14P LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa) |
| | aif1A | eIF1A translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). (115 aa) |
| | secE | Preprotein translocase secE subunit (protein transport protein SEC61 gamma subunit homolog; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (61 aa) |
| | ef1b | EF-1 beta translation elongation factor EF-1, subunit beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (91 aa) |
| | rpoP | rpoP DNA-directed RNA polymerase, subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (49 aa) |
| | PAB3084 | Hypothetical protein. (94 aa) |
| | han1 | Han1 histone-like protein han1 subunit; Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation (in vitro). (67 aa) |
| | rpl39E | rpl39E LSU ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | rps24E | rps24E SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (99 aa) |
| | rpl37AE | rpl37AE LSU ribosomal protein L37AE; Binds to the 23S rRNA. (83 aa) |
| | rps14 | rps14P SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (56 aa) |
| | PAB7082 | suI1-like protein translation factor SUI1 homolog; Belongs to the SUI1 family. (99 aa) |
| | rpl23 | rpl23P LSU ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | rpl35ae | rpl35AE LSU ribosomal protein L35AE; Belongs to the eukaryotic ribosomal protein eL33 family. (87 aa) |
| | albA | Conserved hypothetical protein, DUF78 family; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (93 aa) |
| | rpoN | rpoN DNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (65 aa) |
| | rpoK | rpoK DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (57 aa) |
| | rpoH | rpoH DNA-directed RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (82 aa) |
| | rpl30E | rpl30E LSU ribosomal protein L30E; Belongs to the eukaryotic ribosomal protein eL30 family. (99 aa) |
| | rpl37E | rpl37E LSU ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa) |
| | rps28E | rps28E SSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (71 aa) |
| | rps17e | rps17E SSU ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (67 aa) |
| | rpl40E | rpl40E LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa) |
| | nop10 | Small nucleolar ribonucleoprotein, trans-acting factor intervening in ribosome biogenesis; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (60 aa) |
| | rpL34E | rpl34E LSU ribosomal protein L34E; Belongs to the eukaryotic ribosomal protein eL34 family. (91 aa) |
| | rpl14E | rpl14E LSU ribosomal protein L14E; Belongs to the eukaryotic ribosomal protein eL14 family. (82 aa) |
| | rpl31E | rpl31E LSU ribosomal protein L31E; Belongs to the eukaryotic ribosomal protein eL31 family. (94 aa) |
| | rplXA | rplXA LSU ribosomal protein LXA. (77 aa) |
| | rpoE2 | rpoE2 DNA-directed RNA polymerase, subunit E''. (60 aa) |
| | rps27e | rps27E SSU ribosomal protein S27E. (65 aa) |
| | rpl29 | rpl29P LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (60 aa) |
| | snrnp | Heptameric Sm/Lsm protein; Belongs to the snRNP Sm proteins family. (75 aa) |
| | rpl24E | rpl24E LSU ribosomal protein L24E; Binds to the 23S rRNA. (67 aa) |
| | PABs13722 | Predicted Zn-ribbon RNA-binding protein involved in translation. (66 aa) |
