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| | rps15P | rps15P SSU ribosomal protein S15P. (158 aa) |
| | rps3AE | rps3AE SSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (200 aa) |
| | PAB0066 | alaRS-like alanyl-tRNA synthetase related protein (fragment). (213 aa) |
| | rfcS | rfcS intein containing activator 1, replication factor C, small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-independent ATPase activity; Belongs to the activator 1 small subunits family. RfcS subfamily. (1437 aa) |
| | rfcL | rfcL activator 1, replication factor C, large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-independent ATPase activity; Belongs to the activator 1 small subunits family. RfcL subfamily. (479 aa) |
| | lysS | lysS lysyl-tRNA synthetase. (526 aa) |
| | PAB0161 | Hypothetical protein, containing archaeal Zn-finger. (204 aa) |
| | radA | radA DNA repair protein rad51 : DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity). (356 aa) |
| | PAB0165 | SAM-dependent methyltransferase, putative. (248 aa) |
| | fus | Fus translation elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTP [...] (732 aa) |
| | PAB0190 | Putative ATP-dependent ERCC4-like helicase. (752 aa) |
| | ksgA | ksgA dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (269 aa) |
| | xerD-like | xerC/D integrase/recombinase protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Probably involved in the resolution of chromosome dimers at the terminus of replication. Binds to the dif site. (286 aa) |
| | ogt | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (172 aa) |
| | PAB0278 | RNA binding protein, emap domain. (109 aa) |
| | pimT-like | SAM-dependent methyltransferase, putative; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenosine at position(s) 57 (m1A57) and 58 (m1A58) in the T- loop of some tRNAs. Methylates the first adenine of an AA sequence. Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family. (253 aa) |
| | PAB0284 | Predicted rRNA or tRNA methylase. (197 aa) |
| | dnaG | Primase dnaG-like; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (447 aa) |
| | gltX | gltX glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa) |
| | rnhB | rnhB ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (224 aa) |
| | rps13P | rps13P SSU ribosomal protein S13P/S18E; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (148 aa) |
| | rps4P | rps4P SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa) |
| | rps11P | rps11P SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (137 aa) |
| | rpl18E | rpl18E LSU ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa) |
| | rpl13P | rpl13P LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | rps9P | rps9P SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (135 aa) |
| | rps2P | rps2P SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (202 aa) |
| | glyS | glyS glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (571 aa) |
| | rtcB | rtcB homolog, intein containing; GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends; Belongs to the RtcB family. (916 aa) |
| | prf1 | Prf1 peptide chain release factor subunit 1 (translation termination factor ARF1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (417 aa) |
| | top6B | Top6B DNA topoisomerase VI, subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (564 aa) |
| | psmA | psmA proteasome, subunit alpha (EC 3.4.99.46); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (260 aa) |
| | rrp4 | Predicted exosome subunit, RNA-binding protein rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (265 aa) |
| | rph | Rph ribonuclease PH, exosome complex exonuclease; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails (Probable). (249 aa) |
| | rrp42 | RNAse PH-related exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (274 aa) |
| | nusA | nusA transcription termination-antitermination factor nusA, putative; Participates in transcription termination. Belongs to the NusA family. (145 aa) |
| | rps12P | rps12P SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa) |
| | rps7P | rps7P SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (215 aa) |
| | pth | Hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (121 aa) |
| | nth | Nth endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (222 aa) |
| | rpl7AE | rpl7AE LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (128 aa) |
| | tuf | Tuf translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (428 aa) |
| | rps10P | rps10P SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | pelA | pelA cell division protein pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (356 aa) |
| | argS | argS arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (625 aa) |
| | PAB0474 | Thermostable uracil-DNA glycosylase. (196 aa) |
| | trm5b | Hypothetical protein, Met-10+ like protein; Specifically methylates the N1 position of guanosine-37 in various tRNAs. (330 aa) |
| | PAB0523 | Nucleolar protein from the nop2 family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (311 aa) |
| | hjc | Hjc holliday-junction resolvase; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family. (121 aa) |
| | aif2A | eIF2A translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family. (275 aa) |
| | rpl15E | rpl15E LSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (194 aa) |
| | PAB0588 | Predicted DNA methylase. (1010 aa) |
| | hel308 | DNA helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (715 aa) |
| | taw3-1 | Hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (194 aa) |
| | ileS | ileS isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1067 aa) |
| | aspS | aspS aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (438 aa) |
| | PAB0707 | tatD related DNAse. (253 aa) |
| | PAB0719 | RNA methyltransferase, putative; Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (405 aa) |
| | rpl21E | rpl21E LSU ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa) |
| | rps8E | rps8E SSU ribosomal protein S8E. (127 aa) |
| | infB | infB intein containing translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). (992 aa) |
| | PAB0760 | RNA methyltransferase, putative; Catalyzes the formation of 5-methyl-uridine at position equivalent to 747 (m5U747) in 23S rRNA (m5U859 in the P.abyssi numbering). (410 aa) |
| | rad32 | Rad32/mre11 DNA repair protein (EC 3.1.-.-); Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (423 aa) |
| | rad50 | Rad50 purine ntpase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (880 aa) |
| | PAB0830 | Sun/NOL1/NOP2 nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (449 aa) |
| | PAB0880 | Hypothetical protein. (369 aa) |
| | serS | serS seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (455 aa) |
| | nfi | Nfi endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (194 aa) |
| | cysS | cysS cysteinyl-tRNA synthetase. (477 aa) |
| | eif2b | Translation initiation factor eIF-2, beta subunit, putative; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family. (140 aa) |
| | PAB0974 | Oligosaccharyl transferase, STT3 subunit. (766 aa) |
| | eif-6 | Ribosome anti-association factor eIF6 homolog; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (227 aa) |
| | PAB1040 | Uncharacterized ArCR; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs. Belongs to the aTrm56 family. (198 aa) |
| | nrd | Nrd inteins containing ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (2122 aa) |
| | hisS | hisS histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa) |
| | PAB1103 | Endonuclease IV. (281 aa) |
| | trpS | trpS tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (385 aa) |
| | polI | polI DNA polymerase I. (771 aa) |
| | rpl1 | LSU ribosomal protein L1P (rpl1P); Binds directly to 23S rRNA. Probably involved in E site tRNA release. (219 aa) |
| | rpl10 | rpl10E LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (341 aa) |
| | rpl12 | rpl12A LSU ribosomal protein L12A; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (107 aa) |
| | PAB1173 | Sun/NOL1/NOP nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (385 aa) |
| | PAB1190 | alaRS-like alanyl-tRNA synthetase related protein (fragment). (405 aa) |
| | PAB1205 | Methyltransferase related protein. (208 aa) |
| | pcm | Pcm L-isoaspartyl protein carboxyl methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity). (219 aa) |
| | rpl44e | rpl44E LSU ribosomal protein L44E; Binds to the 23S rRNA. (94 aa) |
| | alaS | alaS alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (914 aa) |
| | valS | valS valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (891 aa) |
| | trmG10 | Methylase, puative RNA modification protein; Catalyzes the adenosylmethionine-dependent methylation of the exocyclic amino group (N(2)) of guanosine at position 10 of various tRNAs. Acts via a two-step process that leads to the formation of either N(2)-monomethyl (m(2)G) or N(2)-dimethylguanosine (m(2)(2)G). (332 aa) |
| | PAB1306 | Putative translation initiation factor eIF-2B delta subunit; Catalyzes the exchange of initiation factor 2-bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family. (276 aa) |
| | mutS2 | mutS-like DNA mismatch recognition protein, muts2 homolog; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (570 aa) |
| | lon | Lon intein containing ATP-dependent protease La homolog; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Degrades polypeptides processively (By similarity); Belongs to the peptidase S16 family. Archaeal LonB subfamily. (998 aa) |
| | cheR | cheR chemotaxis protein methyltransferase. (283 aa) |
| | rps6e | rps6E SSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. (125 aa) |
| | topA | topA DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA [...] (685 aa) |
| | rpl10e | rpl10E ribosomal protein L10; Belongs to the universal ribosomal protein uL16 family. (181 aa) |
| | PAB1452 | Transposon ISC1913 related orf. (404 aa) |
| | pcn | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Regulates activity of NucS endonuclease and prevents non- specific cleavage. (249 aa) |
| | thrS | thrS threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) (Probable). Edits incorrectly charged L-seryl-tRNA(Thr) via its editing domain. Deacylates correctly charged glycyl-tRNA(Gly), but neither glycyl-tRNA(Gly)(2'-dA76) (the terminal 2'-OH of tRNA(Thr) adenine 76 has been replaced by hydrogen) nor the 2'-fluoro tRNA derivative do so, strongly suggesting the editing function is tRNA catalyzed. Belongs to the class-II aminoacyl-tR [...] (625 aa) |
| | nusA-2 | Hypothetical protein, containing KH nucleic acid binding domain. (170 aa) |
| | PAB1504 | Hypothetical protein. (196 aa) |
| | PAB1530 | alkA 3-methyladenine DNA glycosylase. (276 aa) |
| | PAB1586 | Oligosaccharyl transferase, STT3 subunit. (765 aa) |
| | PAB1655 | paaI related protein, phenylacetic acid degradation-related protein. (127 aa) |
| | PAB1687 | Hypothetical protein. (256 aa) |
| | PAB1695 | Hypothetical protein; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates. (239 aa) |
| | proS | proS prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa) |
| | tyrS | tyrS tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (375 aa) |
| | rnj | Metallo-beta-lactamase superfamily protein; A highly processive 5'-3' exoribonuclease; no evidence has been seen for endonuclease activity. Prefers 5'-phosphate or 5'- hydroxyl ends; 5'-triphosphate substrates are very poorly degraded, does not degrade circular RNA. Does not degrade pre-tRNA(Trp) suggesting it is inhibited by strong secondary structures. Also degrades ssNDA but not dsDNA. (451 aa) |
| | leuS | leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (967 aa) |
| | PAB1802 | Transposon ISC1904 linked orf, putative transposase. (414 aa) |
| | rps19e | rps19E SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (150 aa) |
| | nep1 | Hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA (By similarity). (232 aa) |
| | eif5a | Translation initiation factor eIF5A (hypusine containing); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (138 aa) |
| | PAB1857 | Hypothetical protein; Belongs to the glycosyl hydrolase 57 family. (602 aa) |
| | trmY | Hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (204 aa) |
| | fen | Fen1 FLAP endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathw [...] (343 aa) |
| | gatD | L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate; Belongs to the asparaginase 1 family. GatD subfamily. (438 aa) |
| | gatE | Archaeal Glu-tRNAGln amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate; Belongs to the GatB/GatE family. GatE subfamily. (633 aa) |
| | PAB1903 | Hypothetical protein. (649 aa) |
| | PAB1947 | Sun/NOL1/NOP2 nucleolar protein; Catalyzes AdoMet-dependent formation of m5C in tRNA. In the presence of protein archease, specifically methylates the cytosine at position 49 (m5C49) of tRNA. In the absence of archease, catalyzes the formation of m5C at many locations in tRNAs or rRNAs. (311 aa) |
| | lig | Lig DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (559 aa) |
| | eif2g | eIF2G translation initiation factor eIF-2, subunit gamma (eIF2G); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (411 aa) |
| | PAB2062 | Hypothetical protein; Involved in DNA damage repair. (407 aa) |
| | aif1A | eIF1A translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). (115 aa) |
| | rpl14 | rpl14P LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa) |
| | pheT | pheT phenylalanyl-tRNA synthetase, subunit beta. (556 aa) |
| | pheS | pheS phenylalanyl-tRNA synthetase, subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (500 aa) |
| | top-RG | top-RG reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1214 aa) |
| | top6A | Top6A DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (382 aa) |
| | polC | dp2/polC intein containing DNA polymerase II large subunit (EC 2.7.7.7); Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity). (1455 aa) |
| | rps4e | rps4E SSU ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (243 aa) |
| | rpl22 | rpl22P LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (155 aa) |
| | PAB2076 | Resolvase related protein. (212 aa) |
| | PAB2077 | Transposon ISC1913 related orf. (429 aa) |
| | trm1 | TRM1 N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (383 aa) |
| | smc | Smc1 chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1177 aa) |
| | rpl3 | rpl3P LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (361 aa) |
| | rpl4 | rpl4P LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (255 aa) |
| | rpl2 | rpl2P LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (239 aa) |
| | rps19 | rps19P SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (132 aa) |
| | rps3 | rps3P SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (210 aa) |
| | rps17 | rps17P SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (116 aa) |
| | rpl24 | rpl24P LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (121 aa) |
| | rpl5 | rpl5P LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (188 aa) |
| | rps8 | rps8E SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpl6 | rpl6P LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (184 aa) |
| | rpl32e | rpl32E LSU ribosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (130 aa) |
| | rpl19e | rpl19E LSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (151 aa) |
| | rpl18 | rpl18P LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (203 aa) |
| | rps5 | rps5P SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (236 aa) |
| | rpl30 | rpl30P LSU ribosomal protein L30P. (155 aa) |
| | rpl15 | rpl15P LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (147 aa) |
| | PAB2149 | hsdM type I restriction modification enzyme, subunit M. (623 aa) |
| | PAB2150 | hsdS type I restriction-modification enzyme, S subunit. (427 aa) |
| | PAB2154 | hsdR type I restriction-modification enzyme, R subunit. (1104 aa) |
| | taw3-2 | Hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (206 aa) |
| | PAB2202 | Oligosaccharyl transferase, STT3 subunit. (976 aa) |
| | asnS | asnS asparaginyl-tRNA synthetase (EC 6.1.1.22) (asparagine--tRNA ligase) (ASNRS); Belongs to the class-II aminoacyl-tRNA synthetase family. (434 aa) |
| | priL | Eukaryotic-type DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. Displays gap-filling and strand-displacement activities. (393 aa) |
| | priS | DNA primase; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own, synthesizing DNA strands up to 3 kB. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability for RNA fragments up to 150 bases. The DNA polymerase activity may enable DNA primase t [...] (345 aa) |
| | PAB2246 | Site specific DNA-methyltransferase. (464 aa) |
| | nucS | Hypothetical protein, DUF91 family; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures. Binds to ssDNA; Belongs to the NucS endonuclease family. (251 aa) |
| | cdc6 | Cdc6/orc1 cell division control protein 6; Involved in regulation of DNA replication (By similarity). Binds specifically to the oriC region. (432 aa) |
| | polB | dp1/polB intein containing DNA polymerase II small subunit (2.7.7.7); Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity); Belongs to the DNA polymerase delta/II small subunit family. (619 aa) |
| | radB | radB DNA repair and recombination protein; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity). (239 aa) |
| | taw22 | Hypothetical protein, Met-10+ like protein; Catalyzes both the N1-methylation of guanosine and the C7- methylation of 4-demethylwyosine (imG-14) at position 37 in tRNA(Phe). (333 aa) |
| | csl4 | RNA-binding protein, putative, containing S1 RNA binding domain; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (199 aa) |
| | PAB2337 | nrdD anaerobic ribonucleoside triphosphate reductase. (658 aa) |
| | nusG | nusG transcription antitermination protein; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (152 aa) |
| | rpl11 | rpl11P LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (164 aa) |
| | asnS-like | asnS-like asparaginyl-tRNA synthetase related protein. (294 aa) |
| | metS | metS methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (722 aa) |
| | rpl24E | rpl24E LSU ribosomal protein L24E; Binds to the 23S rRNA. (67 aa) |
| | rpl29 | rpl29P LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (60 aa) |
| | rps27e | rps27E SSU ribosomal protein S27E. (65 aa) |
| | rplXA | rplXA LSU ribosomal protein LXA. (77 aa) |
| | rpl31E | rpl31E LSU ribosomal protein L31E; Belongs to the eukaryotic ribosomal protein eL31 family. (94 aa) |
| | rpl14E | rpl14E LSU ribosomal protein L14E; Belongs to the eukaryotic ribosomal protein eL14 family. (82 aa) |
| | rpL34E | rpl34E LSU ribosomal protein L34E; Belongs to the eukaryotic ribosomal protein eL34 family. (91 aa) |
| | rpl40E | rpl40E LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa) |
| | rps17e | rps17E SSU ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (67 aa) |
| | rps28E | rps28E SSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (71 aa) |
| | rpl37E | rpl37E LSU ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa) |
| | rpl30E | rpl30E LSU ribosomal protein L30E; Belongs to the eukaryotic ribosomal protein eL30 family. (99 aa) |
| | rpl35ae | rpl35AE LSU ribosomal protein L35AE; Belongs to the eukaryotic ribosomal protein eL33 family. (87 aa) |
| | rpl23 | rpl23P LSU ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | PAB7082 | suI1-like protein translation factor SUI1 homolog; Belongs to the SUI1 family. (99 aa) |
| | rps14 | rps14P SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (56 aa) |
| | rpl37AE | rpl37AE LSU ribosomal protein L37AE; Binds to the 23S rRNA. (83 aa) |
| | rps24E | rps24E SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (99 aa) |
| | PAB2390 | Sun/NOL1/NOP nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (450 aa) |
| | nusA-3 | Hypothetical protein, containing KH nucleic acid binding domain. (62 aa) |
| | rpl39E | rpl39E LSU ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | ef1b | EF-1 beta translation elongation factor EF-1, subunit beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (91 aa) |
