STRINGSTRING
pyrF pyrF RSP_1450 RSP_1450 RSP_1456 RSP_1456 RSP_1457 RSP_1457 RSP_1460 RSP_1460 carA carA RSP_1893 RSP_1893 RSP_1920 RSP_1920 pyrE pyrE pyrC pyrC RSP_1936 RSP_1936 cbbJ cbbJ purM purM purN purN RSP_1998 RSP_1998 moaC moaC RSP_2086 RSP_2086 envA envA purC purC purS purS purQ purQ trgB trgB RSP_2153 RSP_2153 bcrC bcrC suhB suhB purB purB purC1 purC1 atpH atpH atpA atpA atpG atpG atpD atpD atpC atpC prsA prsA ribF ribF nadE nadE gpt gpt pdxH pdxH purF purF eno eno RSP_2501 RSP_2501 glmU glmU coaX coaX surE surE dcd dcd plsX plsX dgt dgt glpK glpK glpD glpD pyrH pyrH cdsA cdsA dxr dxr fabZ fabZ lpxA lpxA RSP_2715 RSP_2715 lpxB lpxB zwf zwf pgl pgl pgi pgi pgk pgk RSP_3828 RSP_3828 RSP_3739 RSP_3739 RSP_3722 RSP_3722 RSP_3720 RSP_3720 RSP_3694 RSP_3694 RSP_3646 RSP_3646 RSP_3644 RSP_3644 cmk cmk RSP_3546 RSP_3546 RSP_3462 RSP_3462 pdxA pdxA tklB tklB sdhA-2 sdhA-2 dgkA dgkA RSP_3053 RSP_3053 moaA-2 moaA-2 moeA moeA gcpE gcpE coaD coaD tktA tktA purL purL RSP_2937 RSP_2937 RSP_2928 RSP_2928 gmk gmk RSP_2912 RSP_2912 pdxA1 pdxA1 ndk ndk glk glk guaB guaB cbbE cbbE ispD ispD pgpA pgpA cinA cinA HPRT HPRT acpP1 acpP1 lpxD lpxD RSP_6153 RSP_6153 ispF ispF pdhB pdhB pdhAb pdhAb pdhAa pdhAa fbaB fbaB lpxK lpxK RSP_1488 RSP_1488 gpsA gpsA RSP_1516 RSP_1516 purK purK purE purE acsA acsA deoB deoB add add upp upp RSP_1621 RSP_1621 LytB LytB spoT/relA spoT/relA adk adk RSP_1753 RSP_1753 pykA pykA mcl1 mcl1 accA accA ispE ispE RSP_1821 RSP_1821 RSP_1822 RSP_1822 mogA mogA apt apt PurD PurD RSP_1848 RSP_1848 guaA guaA RSP_0029 RSP_0029 fliI fliI RSP_0113 RSP_0113 RSP_0119 RSP_0119 nnrD nnrD nnrE nnrE dht dht RSP_0187 RSP_0187 accC accC RSP_0198 RSP_0198 moaA moaA kynU kynU dxsA dxsA crtE crtE folE2 folE2 idi idi RSP_0338 RSP_0338 cbbI cbbI RSP_0363 RSP_0363 purA purA pyrG pyrG thyA thyA RSP_0445 RSP_0445 RSP_0473 RSP_0473 tmk tmk tal tal RSP_0565 RSP_0565 adk-2 adk-2 acsA-2 acsA-2 nadD nadD RSP_0597 RSP_0597 dut dut RSP_0599 RSP_0599 RSP_0603 RSP_0603 RSP_0625 RSP_0625 thiD thiD thiE thiE thiM thiM RSP_0651 RSP_0651 folD folD RSP_0676 RSP_0676 RSP_0708 RSP_0708 cpdB cpdB psd psd pssA pssA RSP_0735 RSP_0735 mobB mobB mobA mobA carB carB ppnk ppnk RSP_0917 RSP_0917 cinA1 cinA1 accD accD ialA ialA gpmI gpmI purU purU RSP_0955 RSP_0955 pyrD pyrD sucB sucB sucA sucA mcl2 mcl2 RSP_0986 RSP_0986 RSP_0999 RSP_0999 pyrB pyrB pyrC1 pyrC1 plsY plsY atpF atpF atpX atpX atpE atpE atpB atpB moaE moaE moaD moaD pgsA pgsA fdsC fdsC purH purH Dxs Dxs ispA ispA cysQ cysQ RSP_1206 RSP_1206 ham1 ham1 maf maf coaE coaE ackA ackA RSP_1255 RSP_1255 RSP_1294 RSP_1294 RSP_1332 RSP_1332 pncB pncB pncA pncA amn amn
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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pyrFOrotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (232 aa)
RSP_1450IMG reference gene:2512953341; PFAM: Inositol monophosphatase family; TIGRFAM: histidinol-phosphate phosphatase HisN, inositol monophosphatase family. (264 aa)
RSP_1456Phosphotransferase family protein; IMG reference gene:2512953347; PFAM: Phosphotransferase enzyme family. (314 aa)
RSP_1457Putative choline kinase; IMG reference gene:2512953348; PFAM: Choline/ethanolamine kinase. (314 aa)
RSP_1460Hypothetical protein; IMG reference gene:2512953353. (81 aa)
carAIMG reference gene:2512953784; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (387 aa)
RSP_1893IMG reference gene:2512953802; PFAM: Inositol monophosphatase family; TIGRFAM: histidinol-phosphate phosphatase HisN, inositol monophosphatase family. (266 aa)
RSP_1920Pyridoxal kinase; IMG reference gene:2512953832; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: pyridoxal kinase; extended by 17 aa; Belongs to the pyridoxine kinase family. (289 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (232 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (346 aa)
RSP_1936Molybdopterin biosynthesis protein; IMG reference gene:2512953849. (334 aa)
cbbJTriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (245 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2512953883; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase. (348 aa)
purNFormyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (196 aa)
RSP_1998Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (394 aa)
moaCCyclic pyranopterin monophosphate synthase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (159 aa)
RSP_2086IMG reference gene:2512954009; PFAM: Antibiotic biosynthesis monooxygenase. (105 aa)
envAUDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (306 aa)
purCIMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (250 aa)
purSComponent of phosphoribosylformylglycinamidine (FGAM) synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is [...] (79 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (222 aa)
trgBTellurite resistance protein; IMG reference gene:2512954070; PFAM: NUDIX domain; TIGRFAM: nudix-type nucleoside diphosphatase, YffH/AdpP family. (362 aa)
RSP_2153Metallo-phosphoesterase; IMG reference gene:2512954077. (268 aa)
bcrCEfflux channel; IMG reference gene:2512954085; PFAM: PAP2 superfamily. (235 aa)
suhBIMG reference gene:2512954092; PFAM: Inositol monophosphatase family. (261 aa)
purBIMG reference gene:2512954150; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (434 aa)
purC1IMG reference gene:2512954187; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (319 aa)
atpHATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (186 aa)
atpAATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (512 aa)
atpGATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (289 aa)
atpDATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (475 aa)
atpCATP synthase F1 subcomplex epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (132 aa)
prsAPhosphoribosyl pyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (339 aa)
ribFFMN adenylyltransferase; IMG reference gene:2512954238; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (306 aa)
nadENAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (554 aa)
gptXanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (167 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (200 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (487 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
RSP_2501Nicotinate-nucleotide pyrophosphorylase; IMG reference gene:2512954446; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: putative molybdenum utilization protein ModD; Belongs to the NadC/ModD family. (279 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (454 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (257 aa)
surE5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (261 aa)
dcdIMG reference gene:2512954552; PFAM: 2'-deoxycytidine 5'-triphosphate deaminase (DCD). (358 aa)
plsXPhosphate:acyl-(acyl carrier protein) acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (370 aa)
dgtIMG reference gene:2512954604; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. (378 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (493 aa)
glpDHomodimeric glycerol 3-phosphate dehydrogenase (quinone); IMG reference gene:2512954614; PFAM: FAD dependent oxidoreductase; truncated by 7 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (532 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa)
cdsAIMG reference gene:2512954652; PFAM: Cytidylyltransferase family; Belongs to the CDS family. (273 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (394 aa)
fabZ3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (155 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (260 aa)
RSP_2715Hypothetical protein; IMG reference gene:2512954660; PFAM: Protein of unknown function (DUF1009). (273 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (379 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (483 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (223 aa)
pgiGlucose-6-phosphate isomerase; IMG reference gene:2512954681; PFAM: Phosphoglucose isomerase; Belongs to the GPI family. (533 aa)
pgkPhosphoglycerate kinase; IMG reference gene:2512954431; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)
RSP_3828Putative thiamine-phosphate pyrophosphorylase; IMG reference gene:2512956488; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase. (206 aa)
RSP_3739Deoxyribose phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (324 aa)
RSP_3722Hypothetical protein; IMG reference gene:2512957257. (316 aa)
RSP_3720Hypothetical protein; IMG reference gene:2512957255. (317 aa)
RSP_3694Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. (221 aa)
RSP_3646DNA topology modulation kinase FlaR, putative; IMG reference gene:2512957180; extended by 14 aa. (206 aa)
RSP_3644Metal dependent phosphohydrolase; IMG reference gene:2512957178; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. (473 aa)
cmkCytidylate kinase; IMG reference gene:2512957104; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase. (206 aa)
RSP_3546Hypothetical protein; IMG reference gene:2512957056; extended by 107 aa. (238 aa)
RSP_3462Dihydropyrimidinase; IMG reference gene:2512956973; PFAM: Amidohydrolase family; TIGRFAM: D-hydantoinase. (485 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; IMG reference gene:2512956916; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (328 aa)
tklBTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (657 aa)
sdhA-2Putative succinate dehydrogenase/fumarate reductase, flavoprotein subunit; IMG reference gene:2512956656; PFAM: Fumarate reductase flavoprotein C-term; FAD binding domain. (587 aa)
dgkADiacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (126 aa)
RSP_3053Putative dioxygenase/glyoxalase family protein; IMG reference gene:2512956554; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (309 aa)
moaA-2Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (338 aa)
moeAMolybdenum cofactor biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (410 aa)
gcpE4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (377 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa)
tktATransketolase; IMG reference gene:2512954921; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family. (672 aa)
purLPhosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (720 aa)
RSP_2937Putative phosphonate metabolism protein; IMG reference gene:2512954901; PFAM: Protein of unknown function (DUF1045); TIGRFAM: putative phosphonate metabolism protein. (230 aa)
RSP_2928Putative MobA-like protein; IMG reference gene:2512954891. (199 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (211 aa)
RSP_2912Putative pyrophosphatase; IMG reference gene:2512954874; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. (268 aa)
pdxA14-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (322 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
glkPutative glucokinase; IMG reference gene:2512954837; PFAM: Glucokinase; TIGRFAM: glucokinase, proteobacterial type; Belongs to the bacterial glucokinase family. (317 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (482 aa)
cbbEPentose-5-phosphate-3-epimerase; IMG reference gene:2512954740; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (236 aa)
ispDPutative 4-diphosphocytidyl-2C-methyl-D-erythritol synthase (YgbP); Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (225 aa)
pgpAPutative Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (165 aa)
cinAIMG reference gene:2512954773; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. (161 aa)
HPRTHypoxanthine-guanine phosphoribosyltransferase; IMG reference gene:2512954736; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (181 aa)
acpP1Acyl carrier protein, AcpP; IMG reference gene:2512954726; PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein. (88 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; IMG reference gene:2512954725; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. (363 aa)
RSP_6153Putative nucleotide kinase; IMG reference gene:2512956337; PFAM: Protein of unknown function (DUF2478). (174 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa)
pdhBDihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (442 aa)
pdhAbDihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (463 aa)
pdhAaPyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (329 aa)
fbaBFructose-bisphosphate aldolase; IMG reference gene:2512954430; PFAM: DeoC/LacD family aldolase. (309 aa)
lpxKlipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (332 aa)
RSP_1488Putative glyoxalase; IMG reference gene:2512953380. (247 aa)
gpsAIMG reference gene:2512953405; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (305 aa)
RSP_1516Putative S-adenosyl L-homocysteine hydrolase; IMG reference gene:2512953411; PFAM: HD domain. (194 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (360 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa)
acsApropionyl-CoA synthetase; IMG reference gene:2512953489; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; truncated by 8 aa. (630 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (398 aa)
addAdenosine deaminase; IMG reference gene:2512953494; PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase. (327 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (210 aa)
RSP_1621Deoxyguanosinetriphosphate triphosphohydrolase-like protein; IMG reference gene:2512953521; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative. (487 aa)
LytB4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (319 aa)
spoT/relARelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (705 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa)
RSP_1753Hypothetical protein; IMG reference gene:2512953657. (723 aa)
pykAPyruvate kinase; IMG reference gene:2512953671; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa)
mcl1beta-methylmalyl-CoA/L-malyl-CoA lyase; Involved in the ethylmalonyl-CoA pathway for acetate assimilation. Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to yield beta-methylmalyl-CoA. It is also able to catalyze the cleavage of (S)-citramalyl-CoA to yield acetyl-CoA and pyruvate, although this reaction is not involved in the ethylmalonyl- CoA pathway. (318 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (278 aa)
RSP_1821Molybdopterin-containing oxidoreductase, putative formate dehydrogenase; IMG reference gene:2512953729; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (766 aa)
RSP_1822NH(3)-dependent NAD(+) synthetase; IMG reference gene:2512953730; PFAM: Competence-damaged protein; NAD synthase; TIGRFAM: NAD+ synthetase; competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. (514 aa)
mogAIMG reference gene:2512953731; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (181 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (178 aa)
PurDPhosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. (420 aa)
RSP_1848Pyruvate kinase; IMG reference gene:2512953757; PFAM: Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. (508 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (518 aa)
RSP_0029IMG reference gene:2512955012; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Citrate lyase, alpha subunit (CitF); TIGRFAM: succinate CoA transferases. (499 aa)
fliIFliI, Flagellum-specific ATPase; IMG reference gene:2512955045; PFAM: ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family. (442 aa)
RSP_0113IMG reference gene:2512955104; PFAM: Phospholipase D Active site motif; truncated by 15 aa. (483 aa)
RSP_0119PA-phosphatase related phosphoesterase; IMG reference gene:2512955110; PFAM: PAP2 superfamily. (256 aa)
nnrDyjeF-like protein, hydroxyethylthiazole kinase-related protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (278 aa)
nnrEyjeF-like protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (233 aa)
dhtDihydropyrimidinase; IMG reference gene:2512955180; PFAM: Amidohydrolase family; TIGRFAM: D-hydantoinase; truncated by 18 aa. (483 aa)
RSP_0187Dihydropyrimidine dehydrogenase; IMG reference gene:2512955184; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. (434 aa)
accCacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
RSP_0198Phosphatidylglycerophosphate synthase; IMG reference gene:2512955195; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (202 aa)
moaACyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (344 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (396 aa)
dxsA1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (648 aa)
crtEFarnesyl-diphosphate synthase; Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes. Belongs to the FPP/GGPP synthase family. (292 aa)
folE2GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. (359 aa)
idiIsopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (177 aa)
RSP_0338Sphingosine/diacylglycerol kinase-like enzyme; IMG reference gene:2512955347; PFAM: Diacylglycerol kinase catalytic domain. (305 aa)
cbbIRibose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (262 aa)
RSP_0363Thiamine diphosphokinase; IMG reference gene:2512955373; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase. (232 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (547 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (298 aa)
RSP_0445Putative HD superfamily hydrolase; IMG reference gene:2512955455. (194 aa)
RSP_0473phospholipase-D family protein; IMG reference gene:2512955484. (516 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (217 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (219 aa)
RSP_0565CDP-diacylglycerol-choline O-phosphatidyltransferase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (238 aa)
adk-2Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (226 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (653 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (189 aa)
RSP_0597Putative molybdopterin biosynthesis protein; IMG reference gene:2512955612; PFAM: MoeZ/MoeB domain; ThiF family. (348 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (155 aa)
RSP_0599Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (396 aa)
RSP_0603Fructose-2,6-bisphosphatase; IMG reference gene:2512955618; PFAM: Phosphoglycerate mutase family. (192 aa)
RSP_0625Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (192 aa)
thiDHydroxymethylpyrimidine kinase;phosphomethylpyrimidine kinase; IMG reference gene:2512955666; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. (267 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (203 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (262 aa)
RSP_0651IMG reference gene:2512955670; PFAM: Inositol monophosphatase family. (264 aa)
folD5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (296 aa)
RSP_0676PhnP-like protein; IMG reference gene:2512955696. (265 aa)
RSP_0708NUDIX hydrolase; IMG reference gene:2512955729; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain; NADH pyrophosphatase-like rudimentary NUDIX domain. (317 aa)
cpdB2',3'-cyclic-nucleotide 2'-phosphodiesterase; IMG reference gene:2512955730; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; TIGRFAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family. (630 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (232 aa)
pssAIMG reference gene:2512955742; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (245 aa)
RSP_0735IMG reference gene:2512955758; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (241 aa)
mobBIMG reference gene:2512955760; PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB. (452 aa)
mobAMolybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (193 aa)
carBIMG reference gene:2512955846; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; truncated by 4 aa; Belongs to the CarB family. (1099 aa)
ppnkPutative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (254 aa)
RSP_0917IMG reference gene:2512955949; PFAM: Inositol monophosphatase family. (258 aa)
cinA1Putative nucleotide-utilizing enzyme/competence-damage associated protein; IMG reference gene:2512955956; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (243 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (317 aa)
ialANUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (162 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (506 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa)
RSP_09555'-nucleotidase; IMG reference gene:2512955991; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. (523 aa)
pyrDDihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (354 aa)
sucB2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (509 aa)
sucAIMG reference gene:2512956002; PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component. (992 aa)
mcl2Putative citrate lyase beta chain; Catalyzes the hydrolysis of (3S)-malyl-CoA to (3S)-malate and free CoA. Inactive towards beta-methylmalyl-CoA and other CoA esters. (285 aa)
RSP_0986Fructokinase; IMG reference gene:2512956025; PFAM: Phosphoribulokinase / Uridine kinase family. (198 aa)
RSP_0999Putative transcriptional regulator; IMG reference gene:2512956037; PFAM: Uncharacterized ACR, COG1678; Belongs to the UPF0301 (AlgH) family. (184 aa)
pyrBIMG reference gene:2512956040; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (320 aa)
pyrC1Dihydroorotase-related cyclic amidohydrolase; IMG reference gene:2512956041; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. (425 aa)
plsYAcyl-phosphate glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (201 aa)
atpFFoF1 ATP synthase, subunit B; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (184 aa)
atpXFoF1 ATP synthase, subunit B; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). (180 aa)
atpEATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (78 aa)
atpBATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (261 aa)
moaEMolybdopterin converting factor subunit 2; Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family. (146 aa)
moaDMolybdopterin synthase subunit MoaD; IMG reference gene:2512956113; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal. (82 aa)
pgsAPhosphatidylglycerol phosphate synthase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (221 aa)
fdsCFormate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (271 aa)
purHIMG reference gene:2512956145; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (529 aa)
Dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (637 aa)
ispAGeranylgeranyl pyrophosphate synthetase; IMG reference gene:2512956178; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (289 aa)
cysQ3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (264 aa)
RSP_1206Putative phosphohydrolase (mutT/nudix family protein); IMG reference gene:2512956250; PFAM: NUDIX domain. (195 aa)
ham1dITPase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (203 aa)
mafPutative Maf/YceF/YhdE family protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (197 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa)
ackAPutative acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
RSP_1255Phosphate acetyltransferase; IMG reference gene:2512956299; PFAM: MaoC like domain; Phosphate acetyl/butaryl transferase. (473 aa)
RSP_1294IMG reference gene:2512956340; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (727 aa)
RSP_1332H+-transporting two-sector ATPase, alpha/beta subunit; IMG reference gene:2512956378; PFAM: ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family. (436 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (430 aa)
pncAPutative pyrazinamidase/nicotinamidase; IMG reference gene:2512956415; PFAM: Isochorismatase family. (201 aa)
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (492 aa)
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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