(12 nodes) Ribosome network (Rickettsia prowazekii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RP040	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (95 aa)
	RP060	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1). (555 aa)
	RP099	50S RIBOSOMAL PROTEIN L28 (rpmB); Belongs to the bacterial ribosomal protein bL28 family. (97 aa)
	RP234	30S RIBOSOMAL PROTEIN S9 (rpsI); Belongs to the universal ribosomal protein uS9 family. (161 aa)
	RP456	RIBOSOMAL PROTEIN L36 (rpmJ); Belongs to the bacterial ribosomal protein bL36 family. (41 aa)
	RP634	50S RIBOSOMAL PROTEIN L17 (rplQ). (136 aa)
	RP646	CYANELLE 30S RIBOSOMAL PROTEIN S14 (rpsN); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
	RP648	50S RIBOSOMAL PROTEIN L24 (rplX); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (113 aa)
	RP654	50S RIBOSOMAL PROTEIN L22 (rplV); This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (119 aa)
	RP660	30S RIBOSOMAL PROTEIN S10 (rpsJ); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (105 aa)
	RP752	50S RIBOSOMAL PROTEIN L27 (rpmA); Belongs to the bacterial ribosomal protein bL27 family. (86 aa)
	RP773	50S RIBOSOMAL PROTEIN L32 (rpmF); Belongs to the bacterial ribosomal protein bL32 family. (65 aa)

Your Current Organism:

Rickettsia prowazekii

NCBI taxonomy Id: 272947
Other names: R. prowazekii str. Madrid E, Rickettsia prowazekii str. Madrid E, Rickettsia prowazekii strain Madrid E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RP040	RP060	gene:17555123	gene:17555143	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1).	0.999
RP040	RP099	gene:17555123	gene:17555182	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	50S RIBOSOMAL PROTEIN L28 (rpmB); Belongs to the bacterial ribosomal protein bL28 family.	0.999
RP040	RP234	gene:17555123	gene:17555315	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	30S RIBOSOMAL PROTEIN S9 (rpsI); Belongs to the universal ribosomal protein uS9 family.	0.999
RP040	RP456	gene:17555123	gene:17555536	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	RIBOSOMAL PROTEIN L36 (rpmJ); Belongs to the bacterial ribosomal protein bL36 family.	0.999
RP040	RP634	gene:17555123	gene:17555711	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	50S RIBOSOMAL PROTEIN L17 (rplQ).	0.999
RP040	RP646	gene:17555123	gene:17555723	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	CYANELLE 30S RIBOSOMAL PROTEIN S14 (rpsN); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	0.999
RP040	RP648	gene:17555123	gene:17555725	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	50S RIBOSOMAL PROTEIN L24 (rplX); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.999
RP040	RP654	gene:17555123	gene:17555731	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	50S RIBOSOMAL PROTEIN L22 (rplV); This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).	0.999
RP040	RP660	gene:17555123	gene:17555737	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	30S RIBOSOMAL PROTEIN S10 (rpsJ); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.999
RP040	RP752	gene:17555123	gene:17555822	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	50S RIBOSOMAL PROTEIN L27 (rpmA); Belongs to the bacterial ribosomal protein bL27 family.	0.999
RP040	RP773	gene:17555123	gene:17555843	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	50S RIBOSOMAL PROTEIN L32 (rpmF); Belongs to the bacterial ribosomal protein bL32 family.	0.999
RP060	RP040	gene:17555143	gene:17555123	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1).	30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	0.999
RP060	RP099	gene:17555143	gene:17555182	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1).	50S RIBOSOMAL PROTEIN L28 (rpmB); Belongs to the bacterial ribosomal protein bL28 family.	0.999
RP060	RP234	gene:17555143	gene:17555315	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1).	30S RIBOSOMAL PROTEIN S9 (rpsI); Belongs to the universal ribosomal protein uS9 family.	0.999
RP060	RP456	gene:17555143	gene:17555536	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1).	RIBOSOMAL PROTEIN L36 (rpmJ); Belongs to the bacterial ribosomal protein bL36 family.	0.999
RP060	RP634	gene:17555143	gene:17555711	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1).	50S RIBOSOMAL PROTEIN L17 (rplQ).	0.999
RP060	RP646	gene:17555143	gene:17555723	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1).	CYANELLE 30S RIBOSOMAL PROTEIN S14 (rpsN); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	0.999
RP060	RP648	gene:17555143	gene:17555725	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1).	50S RIBOSOMAL PROTEIN L24 (rplX); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.999
RP060	RP654	gene:17555143	gene:17555731	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1).	50S RIBOSOMAL PROTEIN L22 (rplV); This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).	0.999
RP060	RP660	gene:17555143	gene:17555737	ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1).	30S RIBOSOMAL PROTEIN S10 (rpsJ); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.999