STRINGSTRING
RP039 RP039 RP040 RP040 RP041 RP041 RP060 RP060 RP099 RP099 RP100 RP100 RP130 RP130 RP132 RP132 RP136 RP136 RP137 RP137 RP138 RP138 RP139 RP139 RP234 RP234 RP345 RP345 RP456 RP456 RP503 RP503 RP521 RP521 RP606 RP606 RP609 RP609 RP610 RP610 RP633 RP633 RP634 RP634 RP640 RP640 RP643 RP643 RP644 RP644 RP645 RP645 RP646 RP646 RP647 RP647 RP648 RP648 RP650 RP650 RP653 RP653 RP654 RP654 RP655 RP655 RP656 RP656 RP657 RP657 RP658 RP658 RP659 RP659 RP660 RP660 RP752 RP752 RP773 RP773 RP878 RP878
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RP03930S RIBOSOMAL PROTEIN S6 (rpsF); Binds together with S18 to 16S ribosomal RNA. (121 aa)
RP04030S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (95 aa)
RP04150S RIBOSOMAL PROTEIN L9 (rplI); Binds to the 23S rRNA. (171 aa)
RP060ABC TRANSPORTER ATP-BINDING PROTEIN (abcT1). (555 aa)
RP09950S RIBOSOMAL PROTEIN L28 (rpmB); Belongs to the bacterial ribosomal protein bL28 family. (97 aa)
RP10050S RIBOSOMAL PROTEIN L31 (rpmE); Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (78 aa)
RP13030S RIBOSOMAL PROTEIN S12 (rpsL); With S4 and S5 plays an important role in translational accuracy. (129 aa)
RP132ELONGATION FACTOR G (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] (699 aa)
RP13650S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (145 aa)
RP13750S RIBOSOMAL PROTEIN L1 (rplA); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (238 aa)
RP13850S RIBOSOMAL PROTEIN L10 (rplJ); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (169 aa)
RP13950S RIBOSOMAL PROTEIN L7/L12 (rplL); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (125 aa)
RP23430S RIBOSOMAL PROTEIN S9 (rpsI); Belongs to the universal ribosomal protein uS9 family. (161 aa)
RP34530S RIBOSOMAL PROTEIN S4 (rpsD); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (205 aa)
RP456RIBOSOMAL PROTEIN L36 (rpmJ); Belongs to the bacterial ribosomal protein bL36 family. (41 aa)
RP50330S RIBOSOMAL PROTEIN S15 (rpsO); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (91 aa)
RP52130S RIBOSOMAL PROTEIN S1 (rpsA); Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity). (568 aa)
RP606PROBABLE 50S RIBOSOMAL PROTEIN L25 (rplY); This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (203 aa)
RP609CYANELLE 50S RIBOSOMAL PROTEIN L20 (rplT); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). (117 aa)
RP61050S RIBOSOMAL PROTEIN L34 (rpmH); Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
RP63330S RIBOSOMAL PROTEIN S20 (rpsT); Binds directly to 16S ribosomal RNA. (90 aa)
RP63450S RIBOSOMAL PROTEIN L17 (rplQ). (136 aa)
RP64050S RIBOSOMAL PROTEIN L15 (rplO); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (150 aa)
RP64350S RIBOSOMAL PROTEIN L18 (rplR); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (118 aa)
RP64450S RIBOSOMAL PROTEIN L6 (rplF); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
RP64530S RIBOSOMAL PROTEIN S8 (rpsH); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
RP646CYANELLE 30S RIBOSOMAL PROTEIN S14 (rpsN); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
RP64750S RIBOSOMAL PROTEIN L5 (rplE); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
RP64850S RIBOSOMAL PROTEIN L24 (rplX); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (113 aa)
RP65030S RIBOSOMAL PROTEIN S17 (rpsQ); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (77 aa)
RP65330S RIBOSOMAL PROTEIN S3 (rpsC); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (217 aa)
RP65450S RIBOSOMAL PROTEIN L22 (rplV); This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (119 aa)
RP65530S RIBOSOMAL PROTEIN S19 (rpsS); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
RP65650S RIBOSOMAL PROTEIN L2 (rplB); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa)
RP65750S RIBOSOMAL PROTEIN L23 (rplW); One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (98 aa)
RP65850S RIBOSOMAL PROTEIN L4 (rplD); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (207 aa)
RP65950S RIBOSOMAL PROTEIN L3 (rplC); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (216 aa)
RP66030S RIBOSOMAL PROTEIN S10 (rpsJ); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (105 aa)
RP75250S RIBOSOMAL PROTEIN L27 (rpmA); Belongs to the bacterial ribosomal protein bL27 family. (86 aa)
RP77350S RIBOSOMAL PROTEIN L32 (rpmF); Belongs to the bacterial ribosomal protein bL32 family. (65 aa)
RP87830S RIBOSOMAL PROTEIN S16 (rpsP); Belongs to the bacterial ribosomal protein bS16 family. (111 aa)
Your Current Organism:
Rickettsia prowazekii
NCBI taxonomy Id: 272947
Other names: R. prowazekii str. Madrid E, Rickettsia prowazekii str. Madrid E, Rickettsia prowazekii strain Madrid E
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