STRINGSTRING
ppnK ppnK hprK hprK pgk pgk ALA98197.1 ALA98197.1 ALA98204.1 ALA98204.1 tpiA tpiA ALA98271.1 ALA98271.1 ptsI ptsI gmk gmk treP treP pyrH pyrH prs prs ALA98460.1 ALA98460.1 tdk tdk ALA97126.1 ALA97126.1 gpi gpi adk adk ALA97227.1 ALA97227.1 ALA97273.1 ALA97273.1 pfkB pfkB ptsG ptsG ALA97297.1 ALA97297.1 tpk tpk yloV yloV ackA ackA eno eno coaE coaE ldh ldh ALA97389.1 ALA97389.1 cmk cmk gpmI gpmI pfkA pfkA ALA97577.1 ALA97577.1 SKUN_0069 SKUN_0069 ALA97594.1 ALA97594.1 coaX coaX ALA97605.1 ALA97605.1 fbaA fbaA dck dck tmk tmk ALA98055.1 ALA98055.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppnKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (268 aa)
hprKHPr kinase/phosphorylase; Belongs to the HPrK/P family. (307 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (412 aa)
ALA98197.1Deoxynucleoside kinase. (202 aa)
ALA98204.1Deoxynucleoside kinase. (176 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (245 aa)
ALA98271.1PTS system IIB component. (94 aa)
ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (191 aa)
trePPhosphotransferase system PTS,trehalose specific IIBC component. (522 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa)
prsPhosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (339 aa)
ALA98460.1Hypothetical protein. (989 aa)
tdkThymidine kinase. (194 aa)
ALA97126.1Carbamate kinase; Belongs to the carbamate kinase family. (310 aa)
gpiGlucose-6-phosphate isomerase. (424 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa)
ALA97227.1Dihydrolipoamide acetyltransferase. (619 aa)
ALA97273.1PTS system IIBC component. (121 aa)
pfkB1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (310 aa)
ptsGPTS system glucose-specific IIBC component. (694 aa)
ALA97297.1Serine/threonine-protein kinase. (340 aa)
tpkThiamin pyrophosphokinase. (202 aa)
yloVDihydroxyacetone/glyceraldehyde kinase. (539 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (458 aa)
coaEdephospho-CoA kinase; Belongs to the CoaE family. (191 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (318 aa)
ALA97389.1Putative PTS system protein. (522 aa)
cmkCytidylate kinase. (222 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (525 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa)
ALA97577.1Pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
SKUN_00694-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Belongs to the GHMP kinase family. IspE subfamily. (248 aa)
ALA97594.1Diacylglycerol kinase. (142 aa)
coaXTranscriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (254 aa)
ALA97605.1Bifunctional riboflavin kinase/FAD synthetase; Belongs to the ribF family. (295 aa)
fbaAFructose-bisphosphate aldolase. (296 aa)
dckDeoxyadenosine/deoxycytidine kinase. (204 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (214 aa)
ALA98055.1Putative choline kinase. (261 aa)
Your Current Organism:
Spiroplasma kunkelii
NCBI taxonomy Id: 273035
Other names: S. kunkelii CR2-3x, Spiroplasma kunkelii CR2-3x, Spiroplasma kunkelii str. CR2-3x, Spiroplasma kunkelii strain CR2-3x
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