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| | era | Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (297 aa) |
| | polC | DNA polymerase III subunit alpha (PolC); Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1453 aa) |
| | rseP | Inner membrane zinc metalloprotease. (448 aa) |
| | ffh | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (452 aa) |
| | rny | Hypothetical protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (509 aa) |
| | ALA97941.1 | Putative alpha,alpha-phosphotrehalase. (549 aa) |
| | hsdR | Type I restriction enzyme, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (929 aa) |
| | ALA97955.1 | Hypothetical protein. (275 aa) |
| | ALA97031.1 | ATP-dependent Clp protease regulatory subunit. (606 aa) |
| | hit | Histidine triad protein. (138 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (193 aa) |
| | ALA97978.1 | Peptide deformylase. (102 aa) |
| | rnj | Metallo-beta-lactamase family protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (586 aa) |
| | ALA97988.1 | CAAX amino terminal protease. (320 aa) |
| | pfs | 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (226 aa) |
| | nadD | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (365 aa) |
| | xseA | Putative exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (430 aa) |
| | xseB | Putative exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (73 aa) |
| | pepP | Xaa-Pro dipeptidase. (366 aa) |
| | recD | Putative exodeoxyribonuclease V alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (720 aa) |
| | ALA98049.1 | Hypothetical protein. (193 aa) |
| | rdgB | dITP/XTP pyrophosphatase. (86 aa) |
| | ALA98062.1 | Hypothetical protein. (72 aa) |
| | nadE | NH3-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (249 aa) |
| | obgE | GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (434 aa) |
| | ALA98074.1 | Hypothetical protein. (136 aa) |
| | ALA98075.1 | DEAD-box ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (444 aa) |
| | yrrK | Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (139 aa) |
| | relA | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (749 aa) |
| | ALA98146.1 | DEAD/DEAH family helicase. (911 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (654 aa) |
| | ALA98158.1 | DJ-1 family protein. (183 aa) |
| | yrvN | Recombination factor protein RarA. (414 aa) |
| | ftsH | Putative cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (672 aa) |
| | lonA | Class III heat-shock ATP-dependent LonA; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (772 aa) |
| | ppa | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (187 aa) |
| | scpB | Chromosome segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (182 aa) |
| | ALA98209.1 | Hypothetical protein. (116 aa) |
| | ALA98210.1 | Hypothetical protein. (50 aa) |
| | ALA98211.1 | Hypothetical protein. (138 aa) |
| | ALA98214.1 | Hypothetical protein. (449 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (249 aa) |
| | clpB | ATP-dependent protease ATP-binding subunit ClpB; Belongs to the ClpA/ClpB family. (713 aa) |
| | ALA98255.1 | Hydrolase. (287 aa) |
| | ALA98268.1 | Oligoendopeptidase F. (598 aa) |
| | pepA | Leucyl aminopeptidase; Belongs to the peptidase M17 family. (450 aa) |
| | mgtA | Mg(2+) transport ATPase, P-type. (910 aa) |
| | ALA98281.1 | Hypothetical protein. (372 aa) |
| | ALA98299.1 | Hypothetical protein. (333 aa) |
| | ALA97070.1 | Hypothetical protein. (438 aa) |
| | ALA98362.1 | Hypothetical protein. (440 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (950 aa) |
| | ALA98373.1 | Putative membrane-anchored protein. (515 aa) |
| | ALA98380.1 | Hypothetical protein. (591 aa) |
| | ALA98388.1 | HNH endonuclease, putative. (134 aa) |
| | dnaI | Primosomal protein DnaI. (306 aa) |
| | ALA98416.1 | Putative transcriptional regulator. (177 aa) |
| | ALA98428.1 | Hydrolase. (273 aa) |
| | ALA98430.1 | Hypothetical protein. (312 aa) |
| | ftsY | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (328 aa) |
| | rnr | Putative ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (705 aa) |
| | ALA98443.1 | Cof-like hydrolase. (109 aa) |
| | ALA98444.1 | Cof-like hydrolase. (80 aa) |
| | ALA98445.1 | Putative HAD superfamily hydrolase. (276 aa) |
| | atpC | F0F1 ATP synthase subunit epsilon. (87 aa) |
| | bgl | 6-phospho-beta-glucosidase. (50 aa) |
| | ALA98476.1 | Hypothetical protein. (159 aa) |
| | tufA | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (396 aa) |
| | efg | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (692 aa) |
| | ALA98542.1 | Hypothetical protein. (463 aa) |
| | rnpA | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (105 aa) |
| | yxlJ | 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family. (184 aa) |
| | ALA97107.1 | Pyrazinamidase/nicotinamidase. (167 aa) |
| | engD | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa) |
| | ALA97114.1 | Hypothetical protein. (409 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (531 aa) |
| | pth | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (189 aa) |
| | dnaN | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa) |
| | arcA | Arginine deiminase. (399 aa) |
| | ALA97146.1 | Metallo-beta-lactamase superfamily hydrolase. (555 aa) |
| | cbiO-2 | ABC-type cobalt transport system ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (305 aa) |
| | dnaC | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (458 aa) |
| | map | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (247 aa) |
| | uvrD | ATP-dependent DNA helicase. (729 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (512 aa) |
| | smc | SMC superfamily protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (988 aa) |
| | ALA97228.1 | 3'-5' exoribonuclease YhaM. (313 aa) |
| | ALA97239.1 | Haloacid dehalogenase-like hydrolase. (269 aa) |
| | ALA97264.1 | Hypothetical protein. (313 aa) |
| | leuS | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (805 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (617 aa) |
| | prpC | Phosphorylated protein phosphatase. (253 aa) |
| | engC | Ribosome biogenesis GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (289 aa) |
| | dnaE | DNA polymerase III subunit alpha. (1013 aa) |
| | ALA97340.1 | Putative arylesterase. (123 aa) |
| | recU | Holliday junction-specific endonuclease; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation. Belongs to the RecU family. (80 aa) |
| | pldB | Lysophospholipase. (51 aa) |
| | ALA97366.1 | Hypothetical protein. (146 aa) |
| | ALA97367.1 | HAD superfamily hydrolase. (281 aa) |
| | ALA97368.1 | Hypothetical protein. (69 aa) |
| | ALA97369.1 | Hypothetical protein. (164 aa) |
| | ALA97378.1 | Hydrolase. (217 aa) |
| | ALA97408.1 | Glycoprotease. (190 aa) |
| | ALA97437.1 | Putative MoxR-like ATPase. (513 aa) |
| | ALA97439.1 | dUTP diphosphatase. (169 aa) |
| | ALA97449.1 | HAD family hydrolase. (140 aa) |
| | ALA97450.1 | HAD family hydrolase. (58 aa) |
| | ALA97459.1 | ATP-dependent RNA helicase. (458 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (888 aa) |
| | tadA | tRNA-specific adenosine deaminase. (159 aa) |
| | trmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (449 aa) |
| | ALA97498.1 | Hypothetical protein. (104 aa) |
| | SKUN_0061 | Putative deoxyribonuclease. (256 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (600 aa) |
| | ALA97541.1 | Zinc metallopeptidase. (229 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (411 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (908 aa) |
| | lpsA | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (195 aa) |
| | ALA97557.1 | Putative transmembrane protein. (461 aa) |
| | comEB | Deoxycytidylate deaminase. (166 aa) |
| | rnmV | Primase-like protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. (172 aa) |
| | rnhC | Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (299 aa) |
| | aguA | Agmatine deiminase. (370 aa) |
| | uvrC | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (593 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (869 aa) |
| | ybeY | Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (158 aa) |
| | cddA | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (131 aa) |
| | ALA97596.1 | Hypothetical protein. (356 aa) |
| | folD | Tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase. (277 aa) |
| | ALA97697.1 | Hydrolase. (101 aa) |
| | ALA97698.1 | Putative hydrolase of the HAD family. (97 aa) |
| | yqeH | GTP-binding protein YqeH. (358 aa) |
| | yqeG | Putative phosphatase HAD-superfamily/subfamily IIIa protein. (198 aa) |
| | ALA97702.1 | Lipolytic enzyme, GDSL family. (376 aa) |
| | ALA97768.1 | Competence/damage inducible protein; Belongs to the CinA family. (87 aa) |
| | ALA97780.1 | Hypothetical protein. (89 aa) |
| | ALA97781.1 | Hypothetical protein. (170 aa) |
| | ALA97821.1 | Hypothetical protein. (157 aa) |
| | nfo | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (308 aa) |
| | ALA97834.1 | Hypothetical protein. (104 aa) |
| | ALA97855.1 | Hypothetical protein. (61 aa) |
| | ctp | Cation-transporting ATPase. (940 aa) |
| | ung | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (220 aa) |
