STRINGSTRING
queC queC SSO0255 SSO0255 SSO0354 SSO0354 folE folE trzA-like trzA-like gch3 gch3 ribH ribH ribC ribC ribA ribA SSO0403 SSO0403 SSO0544 SSO0544 queE queE SSO0995 SSO0995 NadC NadC nadB nadB nadA nadA ribD ribD nadE nadE SSO2174 SSO2174 nadK nadK SSO2278 SSO2278 SSO2279 SSO2279 SSO2412 SSO2412 SSO2415 SSO2415
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
queCTranscription regulator (exsB) related protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)); Belongs to the QueC family. (464 aa)
SSO0255Nicotinamide mononucleotide adenylyltransferase, putative; Amino-end extention is missing compared to other homologues; Cofactor Biosynthesis, Pyridine nucleotides. (117 aa)
SSO0354Nicotinic acid phosphoribosyltransferase, putative; Cofactor Biosynthesis, Pyridine nucleotides. (387 aa)
folEGTP cyclohydrolase I (folE); Purines. (208 aa)
trzA-likeClose hit to N ethylammeline chlorohydrolase related protein; Cellular Processes. (379 aa)
gch3Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family. (231 aa)
ribHRiboflavin synthase beta chain (6,7 dimethyl 8-ribityllumazine synthase) (DMRKL synthase) (ribH); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (154 aa)
ribCRiboflavin synthase (ribC); Cofactor Biosynthesis, Riboflavin. (155 aa)
ribAGTP Cyclohydrolase II (3,4-Dihydroxy-2-Butanone 4- Phosphate Synthase (DHBP synthase) (ribA); Cofactor Biosynthesis, Riboflavin. (219 aa)
SSO0403Conserved hypothetical protein. (252 aa)
SSO0544Conserved hypothetical protein. (245 aa)
queEConserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (211 aa)
SSO0995Conserved hypothetical protein. (123 aa)
NadCNicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (275 aa)
nadBAspartate oxidase (nadB); Catalyzes the oxidation of L-aspartate to iminoaspartate. (487 aa)
nadAQuinolinate synthetase (nadA); Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (311 aa)
ribD5-amino-6-(5-phosphoribosylamino)uracil reductase (ribD); Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6- ribitylamino-4(3H)-pyrimidinone 5'-phosphate. (213 aa)
nadENH(3+) dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (304 aa)
SSO2174Amidohydrolase, putative; Related to NH(3)-dependent NAD synthetase; Uncategorized. (270 aa)
nadKConserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (249 aa)
SSO2278MutT-like protein; Belongs to the nudix hydrolase family; Cellular Processes, Detoxification. (164 aa)
SSO2279Hypothetical protein. (433 aa)
SSO2412Conserved hypothetical protein; Putative 6-pyruvoyl tetrahydrobiopterin synthase. (138 aa)
SSO2415Dihydropteroate synthase, putative; Cofactor Biosynthesis. (498 aa)
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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