39 items (Saccharolobus solfataricus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SSO2816	2-oxoacid--ferredoxin oxidoreductase, beta chain; Energy Metabolism. (316 aa)
	SSO0535	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa)
	ilvB-2	Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate. (572 aa)
	porD-2	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-2); Energy Metabolism. (94 aa)
	acd-1	Acyl-CoA dehydrogenase (acd-1); Lipid metabolism. (363 aa)
	acd-like1	Acyl-CoA dehydrogenase related protein (acd-like1); Lipid metabolism. (266 aa)
	porG-1	Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (porG-1); Energy Metabolism. (190 aa)
	acsA-1	Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-1); Lipid metabolism. (529 aa)
	acsA-2	Acetyl-CoA synthetase (acetate-CoA ligase) carboxy-end fragment. (acsA-2); Interrupted by transposase in ISC1316. Amino-end is SSO1342; Lipid metabolism. (260 aa)
	acsA-2-2	Acetyl-CoA synthetase (acetate-CoA ligase) amino-end fragment. (acsA-2); Interrupted by transposase in ISC1316. Carboxy-end is SSO1340; Lipid metabolism. (287 aa)
	pdhA-1	Pyruvate dehydrogenase, alpha subunit (lipoamide). (pdhA-1); Strong similarity to acetoin:DCPIP oxidoreductase-alpha (acoA) gene from R. eutropha; Energy Metabolism, Dehydrogenases. (345 aa)
	pdhB-1	Pyruvate dehydrogenase, beta subunit (lipoamide). (pdhB-1); Strong similarity to acetoin:DCPIP oxidoreductase-beta (acoB) gene from R. eutropha; Energy Metabolism, Dehydrogenases. (332 aa)
	pdhA-2	Pyruvate dehydrogenase, alpha subunit (lipoamide). (pdhA-2); Strong similarity to acetoin:DCPIP oxidoreductase-alpha (acoA) gene from R. eutropha; Energy Metabolism, Dehydrogenases. (332 aa)
	pdhB-2	Pyruvate dehydrogenase, beta subunit (lipoamide). (pdhB-2); Strong similarity to acetoin:DCPIP oxidoreductase-beta (acoB) gene from R. eutropha; Energy Metabolism, Dehydrogenases. (324 aa)
	acsA-4	Acetyl-CoA synthetase (acetate-CoA ligase) amino-end fragment (acsA-4); Possible frameshift with SSO2021; Lipid metabolism. (288 aa)
	acsA-4-2	Acetyl-CoA synthetase (acetate-CoA ligase) carboxy-end fragment (acsA-4); Possible frameshift with SSO2020 and SSO9518; Lipid metabolism. (267 aa)
	acsA-6	Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-6); Lipid metabolism. (622 aa)
	acd-3	Acyl-CoA dehydrogenase (acd-3); Lipid metabolism. (371 aa)
	iorB	Indolepyruvate ferredoxin oxidoreductase beta subunit (iorB); Energy Metabolism. (194 aa)
	acsA-7	Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-7); Lipid metabolism. (608 aa)
	porD-like	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-like); Contains long amino-end extension, only present in M. thermoautrophicum MTH1740 gene; Energy Metabolism. (363 aa)
	acsA-8	Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-8); Lipid metabolism. (571 aa)
	SSO2287	Probable acyl-coenzyme a thioester hydrolase; Lipid metabolism. (318 aa)
	Mce	Lactoylglutathione lyase (glyoxalase I), putative; Energy Metabolism. (142 aa)
	acd-like2	Acyl-CoA dehydrogenase related protein (acd-like2); Lipid metabolism. (299 aa)
	acd-4	Acyl-CoA dehydrogenase (acd-4); Lipid metabolism. (370 aa)
	porG-2	Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (porG-2); Energy Metabolism. (184 aa)
	acd-5	Acyl-CoA dehydrogenase (acd-5); Lipid metabolism. (398 aa)
	acsA-3-2	Acetyl-CoA synthetase (acetate-CoA ligase) carboxy-end fragment. (acsA-3); Interrupted by ISC1439 transposase. Amino-end is SSO1903; Lipid metabolism. (74 aa)
	porD-1	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-1); Energy Metabolism. (88 aa)
	acsA-10	Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-10); Lipid metabolism. (652 aa)
	MvaD	Diphosphomevalonate decarboxylase, putative; Catalyzes the decarboxylation of mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. Belongs to the diphosphomevalonate decarboxylase family. (325 aa)
	SSO2988	(Phospho) mevalonate kinase, putative; Catalyzes the phosphorylation of (R)-mevalonate 5-phosphate (MVAP) to (R)-mevalonate 5-diphosphate (MVAPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. (323 aa)
	acd-6	Acyl-CoA dehydrogenase (acd-6); Lipid metabolism. (400 aa)
	acsA-9	Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-9); Lipid metabolism. (666 aa)
	SSO2815	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism. (632 aa)
	tkt-1	Transketolase, N-terminal section (tkt-1); Energy Metabolism, Sugar metabolism. (281 aa)
	tkt-2	Transketolase, C-terminal section (tkt-2); Energy Metabolism, Sugar metabolism. (313 aa)
	mvk	Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (314 aa)

Your Current Organism:

Saccharolobus solfataricus

NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MvaD	SSO0535	SSO2989	SSO0535	Diphosphomevalonate decarboxylase, putative; Catalyzes the decarboxylation of mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. Belongs to the diphosphomevalonate decarboxylase family.	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	0.956
MvaD	SSO2988	SSO2989	SSO2988	Diphosphomevalonate decarboxylase, putative; Catalyzes the decarboxylation of mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. Belongs to the diphosphomevalonate decarboxylase family.	(Phospho) mevalonate kinase, putative; Catalyzes the phosphorylation of (R)-mevalonate 5-phosphate (MVAP) to (R)-mevalonate 5-diphosphate (MVAPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family.	0.998
MvaD	mvk	SSO2989	SSO0383	Diphosphomevalonate decarboxylase, putative; Catalyzes the decarboxylation of mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. Belongs to the diphosphomevalonate decarboxylase family.	Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.989
SSO0535	MvaD	SSO0535	SSO2989	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Diphosphomevalonate decarboxylase, putative; Catalyzes the decarboxylation of mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. Belongs to the diphosphomevalonate decarboxylase family.	0.956
SSO0535	SSO2815	SSO0535	SSO2815	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.	0.900
SSO0535	SSO2816	SSO0535	SSO2816	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	2-oxoacid--ferredoxin oxidoreductase, beta chain; Energy Metabolism.	0.907
SSO0535	SSO2988	SSO0535	SSO2988	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	(Phospho) mevalonate kinase, putative; Catalyzes the phosphorylation of (R)-mevalonate 5-phosphate (MVAP) to (R)-mevalonate 5-diphosphate (MVAPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family.	0.710
SSO0535	mvk	SSO0535	SSO0383	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.903
SSO0535	porD-1	SSO0535	SSO7412	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-1); Energy Metabolism.	0.900
SSO0535	porD-2	SSO0535	SSO11071	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-2); Energy Metabolism.	0.900
SSO0535	porD-like	SSO0535	SSO2128	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-like); Contains long amino-end extension, only present in M. thermoautrophicum MTH1740 gene; Energy Metabolism.	0.900
SSO0535	porG-1	SSO0535	SSO1208	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (porG-1); Energy Metabolism.	0.912
SSO0535	porG-2	SSO0535	SSO2758	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (porG-2); Energy Metabolism.	0.912
SSO2815	SSO0535	SSO2815	SSO0535	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	0.900
SSO2815	SSO2816	SSO2815	SSO2816	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.	2-oxoacid--ferredoxin oxidoreductase, beta chain; Energy Metabolism.	0.999
SSO2815	acsA-7	SSO2815	SSO2070	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.	Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-7); Lipid metabolism.	0.915
SSO2815	acsA-8	SSO2815	SSO2216	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.	Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-8); Lipid metabolism.	0.915
SSO2815	acsA-9	SSO2815	SSO2863	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.	Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-9); Lipid metabolism.	0.915
SSO2815	ilvB-2	SSO2815	SSO0579	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.	Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate.	0.914
SSO2815	iorB	SSO2815	SSO2069	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.	Indolepyruvate ferredoxin oxidoreductase beta subunit (iorB); Energy Metabolism.	0.803