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| | SSO1657 | Conserved hypothetical protein; Best similarity with Pyrococcus. (126 aa) |
| | ssh7A-3 | 7 KD DNA-binding protein (SSO7D) (SSH7A) (ssh7A; Uncategorized. (64 aa) |
| | SSO9500 | Conserved hypothetical protein; Multicopy (SSO8861,SSO7239).Similar to AF0556, Ta1414, Ta1170, AF0188,TM0983, MJ0990. Contains uncharacterized protein family UPF0033 signature. (80 aa) |
| | rpoM-2 | DNA-directed RNA polymerase, subunit M (rpoM-2); Transcription, RNA polymerase and transcription factors. (92 aa) |
| | ssh7A-2 | 7 KD DNA-binding protein (SSO7D) (SSH7A) (ssh7A; Can constrain negative DNA supercoils. May be involved in maintaining the integrity of the genome at high temperature (By similarity). Has RNase activity. Has a narrow substrate specificity; the cleavage products are 3'-phosphooligonucleotides. (64 aa) |
| | SSO8861 | Conserved hypothetical protein; Multicopy (SSO7239,SSO9500).Similar to AF0556, Ta1414, Ta1170, AF0188,TM0983, MJ0990. Contains uncharacterized protein family UPF0033 signature. (80 aa) |
| | SSO8813 | Conserved hypothetical protein; Similarity with Carboxy-end of PAB0859, PAB1216, AF0065. (90 aa) |
| | cas22 | Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity). (88 aa) |
| | SSO7239 | Conserved hypothetical protein; Multicopy (SSO8861,SSO9500).Similar to AF0556, Ta1414, Ta1170, AF0188,TM0983, MJ0990. Contains uncharacterized protein family UPF0033 signature. (80 aa) |
| | nop10 | Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (56 aa) |
| | gatC | Glutamyl-tRNA-Gln amidotransferase, subunit C (gatC); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (97 aa) |
| | rpoK | DNA-directed RNA polymerase subunit K (rpoK); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (95 aa) |
| | SSO6663 | Hypothetical protein. (52 aa) |
| | snRNP-2 | Small nuclear riboprotein protein (snRNP-2); Transcription, RNA modification. (79 aa) |
| | rpoP | DNA-directed RNA polymerase, subunit P (rpoP); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (48 aa) |
| | truB-2 | tRNA pseudouridine synthase subunit A (truB); It may also have a function in cell cycle, it is a cbf5 homolog; Translation, Aminoacyl tRNA synthetases. (89 aa) |
| | rpoL | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (92 aa) |
| | SSO5559 | Hypothetical protein. (83 aa) |
| | SSO5542 | Conserved hypothetical protein; Some similarity with AF0708. (82 aa) |
| | rps28E | SSU ribosomal protein S28E (rps28E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS28 family. (98 aa) |
| | rpoH | DNA-directed RNA polymerase, subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (84 aa) |
| | snRNP-1 | Small nuclear riboprotein protein (snRNP-1); Transcription, RNA modification. (87 aa) |
| | rpoN | DNA-directed RNA polymerase, subunit N (rpoN); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (66 aa) |
| | rpoB2 | DNA-directed RNA polymerase, subunit B'' (rpoB2); Transcription, RNA polymerase and transcription factors; Belongs to the RNA polymerase beta chain family. (480 aa) |
| | tmcA-2 | Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (770 aa) |
| | TsaA | VirR related conserved hypothetical protein; Uncategorized. (124 aa) |
| | SSO3128 | Hypothetical protein. (133 aa) |
| | SSO3088 | Hypothetical protein. (324 aa) |
| | SSO3078 | Conserved hypothetical protein. (134 aa) |
| | SSO2634 | Conserved hypothetical protein. (140 aa) |
| | SSO2579 | Hypothetical protein. (126 aa) |
| | thrS | Threonyl-tRNA synthetase (thrS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr); unlike most archaea the editing function is found in a freestanding protein (ACQ980D1). In vitro when both subunits are present, or if the 2 subunits are fused, L-seryl-tRNA(Thr) is no longer produced, the 2 subunits edit incorrectly charged L-seryl- tRNA(Thr). Has no activity on correctly acylated L- seryl-tRNA(Ser) [...] (545 aa) |
| | nfi | Endonuclease V (nfi); DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (198 aa) |
| | rtcA | RNA 3' terminal phosphate cyclase (RNA 3' phosphate cyclase) (RNA cyclase) (rtcA); Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). (345 aa) |
| | taw21 | Conserved hypothetical protein; Catalyzes the C7-methylation of 4-demethylwyosine (imG-14) at position 37 in tRNA(Phe). (262 aa) |
| | rnhB | Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (212 aa) |
| | SSO2380 | Conserved hypothetical protein; Similar to APE1530 and MJ0867. (421 aa) |
| | SSO2373 | Conserved hypothetical protein; MJ0443. (189 aa) |
| | cysS | Cysteinyl-tRNA synthetase (cysS); Translation, Aminoacyl tRNA synthetases. (470 aa) |
| | dtdA | Conserved hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. Catalyzes the hydrolysis of D- tyrosyl-tRNA(Tyr). (238 aa) |
| | nep1 | Conserved hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (223 aa) |
| | rnp4 | Conserved hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (106 aa) |
| | SSO2223 | Conserved hypothetical protein; Similarity with APE1106, PH1416, PAB0505, Ta0926, PH0115, PAB2272, MJ0883, APE0815, MTH1873, AF0704. (276 aa) |
| | SSO2218 | Conserved hypothetical protein; Similarity with PH0709, PAB0882, MTH1862, MJ1474, AF0385. (158 aa) |
| | SSO2201 | Conserved hypothetical protein. (196 aa) |
| | SSO2151 | Conserved hypothetical protein; Similarity with aq_477. (113 aa) |
| | SSO2096 | Conserved hypothetical protein. (123 aa) |
| | SSO2022 | Ring oxydation complex/ phenylacetic acid degradation related protein; Cellular Processes, Detoxification. (266 aa) |
| | SSO1975 | Conserved hypothetical protein; Similarity with PAB2079, AF1690, AF1479, MJ1121, MJ0914, PAB1585. (125 aa) |
| | SSO1970 | Conserved hypothetical protein; Multicopy, similar to SSO0798, SSO1243. (130 aa) |
| | SSO1969 | Hypothetical protein. (132 aa) |
| | SSO1968 | Conserved hypothetical protein; Similarity with PAB0859, PAB1216, AF0065, AF2012. (128 aa) |
| | SSO1922 | Conserved hypothetical protein; Predicted. Similarity with PH0389. (131 aa) |
| | SSO1914 | Hypothetical protein. (137 aa) |
| | SSO1786 | Hypothetical protein. (143 aa) |
| | SSO1746 | Conserved hypothetical protein. (131 aa) |
| | SSO1651 | Hypothetical protein; Predicted / Weak similarity with AF1385. (131 aa) |
| | SSO1493 | Conserved hypothetical protein; Partial overlap with other ORF. (107 aa) |
| | vapC | Conserved hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (148 aa) |
| | cas21 | Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Involved in the integration of spacer DNA into the CRISPR cassette (By similarity). Functions as a ssRNA-specific endoribonuclease, producing a 5'-phosphomonoester [...] (101 aa) |
| | paaX | Repressor in ring oxydation complex/ phenylacetic acid degradation pathway related protein (paaX); Cellular Processes, Detoxification. (266 aa) |
| | alaS-like2 | Alanyl-tRNA synthetase truncated homolog (alaS-like2); Similar to other truncated alanine--tRNA ligase homologs found in Pyrococcus (PAB1440 and PH0574); Translation, Aminoacyl tRNA synthetases. (150 aa) |
| | SSO1243 | Conserved hypothetical protein; Multicopy, similar to SSO1970, SSO0798. (130 aa) |
| | SSO11939 | Conserved hypothetical protein. (82 aa) |
| | fau-1 | Conserved hypothetical protein; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. (424 aa) |
| | SSO1087 | Conserved hypothetical protein; Similar to carbamoylphosphate synthetase APE0498 (Aeropyrum pernix). (308 aa) |
| | SSO10788 | Conserved hypothetical protein; Similarity with AF0556,YRKI_BACSU, Ta1414, Ta1170. (77 aa) |
| | ssh7A | 7 KD DNA-binding protein (SSO7D) (SSH7A) (ssh7A; Can constrain negative DNA supercoils. May be involved in maintaining the integrity of the genome at high temperature (By similarity). Stimulates the Holliday junction cleavage activity of Hjc ; Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family. (68 aa) |
| | SSO1059 | Hypothetical protein. (213 aa) |
| | priS | DNA primase, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May [...] (330 aa) |
| | SSO1044 | Conserved hypothetical protein. (314 aa) |
| | rnz | Conserved hypothetical protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (291 aa) |
| | cca | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (412 aa) |
| | SSO10051 | Conserved hypothetical protein; Similarity with APE1091, PH1323, PAB1812, AF2070. (89 aa) |
| | SSO0972 | Conserved hypothetical protein. (370 aa) |
| | rtcB | Conserved hypothetical protein; Belongs to the RtcB family. (482 aa) |
| | taw1 | Conserved hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (365 aa) |
| | tfIID | TATA box binding protein, hypothetical (tfIID); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity). (181 aa) |
| | TFB-2 | Transcription initiation factor IIB (TFIIB) homolog (TFB-2); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (293 aa) |
| | trm1 | N2,N2 dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (378 aa) |
| | flpA | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. (232 aa) |
| | gatB-2 | Glutamyl-tRNA -Gln amidotransferase, subunit B (gatB-2); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (633 aa) |
| | valS | Valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (842 aa) |
| | SSO0873 | Conserved hypothetical protein; Conserved in archaea. (219 aa) |
| | argS | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. (625 aa) |
| | SSO0807 | Hypothetical protein. (221 aa) |
| | SSO0798 | Conserved hypothetical protein; Multicopy, similar to SSO1970, SSO1243. (130 aa) |
| | SSO0781 | Conserved hypothetical protein; Belongs to the UPF0148 family. (118 aa) |
| | SSO0779 | Conserved hypothetical protein. (360 aa) |
| | SSO0773 | Hypothetical protein. (172 aa) |
| | rpoF | DNA-directed RNA polymerase, subunit F (rpoF); Transcription. (113 aa) |
| | erm/ksgA | rRNA adenine N-6-methyltransferase (erm/ksgA); Multiple homologs; Translation, RNA modification; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (194 aa) |
| | SSO0747 | Conserved hypothetical protein. (237 aa) |
| | SSO0740 | Hypothetical protein. (186 aa) |
| | rnp2 | Hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (143 aa) |
| | rrp4 | Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. Belongs to the RRP4 family. (249 aa) |
| | rph | Ribonuclease PH (rph); Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. Binds RNA. Belongs to the RNase PH family. Rrp41 subfamily. (248 aa) |
| | rrp42 | Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site; Belongs to the RNase PH family. Rrp42 subfamily. (275 aa) |
| | SSO0731 | Hypothetical protein; Probably involved in the biogenesis of the ribosome. (170 aa) |
| | ileS | Isoleucine-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (986 aa) |
| | rpl30AB | LSU ribosomal protein L30AB (rpl30AB); Translation, Ribosomal Proteins. (158 aa) |
| | SSO0690 | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity). (139 aa) |
| | SSO0664 | SUA5 related conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (358 aa) |
| | SSO0658 | Conserved hypothetical protein. (224 aa) |
| | SSO0646 | Conserved hypothetical protein. (197 aa) |
| | metS-like | Methionyl-tRNA synthetase N-term homolog (metS-like); Translation, Aminoacyl tRNA synthetases. (162 aa) |
| | taw3 | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (209 aa) |
| | SSO0605 | Zn finger protein, hypothetical; Similar to rpoM; Uncategorized. (116 aa) |
| | serS | Seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (457 aa) |
| | leuS-2 | Leucyl-tRNA synthetase (leuS-2); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. (944 aa) |
| | SSO0586 | Conserved hypothetical protein. (323 aa) |
| | proS | Prolyl -tRNA synthetase (proS); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (481 aa) |
| | metS | Methionyl-tRNA synthetase (metS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. (573 aa) |
| | priL | Conserved hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. Possesses a template- independent 3'-terminal nucleotidyl transferase activity. (307 aa) |
| | SSO0551 | Conserved hypothetical protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (208 aa) |
| | leuS-1 | Leucyl-tRNA synthetase (leuS-1); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. (934 aa) |
| | SSO0480 | Histone acethyltransferase, putative; Also a hit to C.elegans ZK863.3; Translation, Protein modification. (473 aa) |
| | SSO0479 | Conserved hypothetical protein. (182 aa) |
| | trpS | Tryptophanyl-tRNA synthetase (trpS); Homology to human, rabbit and yeast versions of protein; Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. (386 aa) |
| | alaS-like1 | Alanyl-tRNA synthetase truncated homolog (alaS-like1); Functions in trans to edit the amino acid moiety from incorrectly charged Ser-tRNA(Ala). (236 aa) |
| | TFB-1 | Transcription initiation factor IIB (TFIIB) homolog (TFB-1); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (309 aa) |
| | glyS | Glycyl-tRNA synthetase (glyS); Translation, Aminoacyl tRNA synthetases. (574 aa) |
| | endA | tRNA intron endonuclease, putative; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (182 aa) |
| | kae1 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. (246 aa) |
| | SSO0433 | O-sialoglycoprotein endopeptidase; Protein modification. (223 aa) |
| | SSO0427 | Protein L-isoaspartate methyltransferase; Protein modification. (256 aa) |
| | rpoE1 | DNA-directed RNA polymerase, subunit E' (rpoE1); Transcription, RNA polymerase and transcription factors. (180 aa) |
| | SSO0414 | Conserved hypothetical protein. (145 aa) |
| | truB | tRNA pseudouridine synthase subunit B (truB); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (251 aa) |
| | tmcA | Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (743 aa) |
| | thrS-like | Threonyl-tRNA synthetase homolog (thrS-like); Freestanding tRNA editing subunit of threonine--tRNA ligase, the catalytic subunit is AC Q97VW8. Deacylates (edits) mischarged L- seryl-tRNA(Thr) in trans, removing L-serine, has no aminoacylation activity. In vitro when both subunits are present, or if the 2 subunits are fused, L-seryl-tRNA(Thr) is no longer produced. Has no activity on correctly acylated L-seryl-tRNA(Ser) or L-threonyl-tRNA(Thr). Editing is probably catalyzed by the 2'-OH of A76 of tRNA(Thr) (By similarity); Belongs to the class-II aminoacyl-tRNA synthetase family. Archae [...] (386 aa) |
| | sun-1 | NOL1/NOP2/sun family protein. Related to eucaryotic proliferating-cell nucleolar protein p120; Cellular Processes. (327 aa) |
| | eiF6 | Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family. (223 aa) |
| | rpl1AB | LSU ribosomal protein L1AB (rpl1AB); Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA (Probable). (218 aa) |
| | alaS | Alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (900 aa) |
| | thiI | Thiamine biosynthesis protein thiI (thiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (371 aa) |
| | csl4 | Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa) |
| | rpoM-1 | DNA-directed RNA polymerase, subunit M (rpoM-1); Possible in-frame shift with SSO5576. Similar to carboxy-end of RPOM_SULAC, but most other thermophilic genes are the same size; Transcription, RNA polymerase and transcription factors; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (114 aa) |
| | SSO0281 | Hypothetical protein; Weak similarity with tRNA intron endonuclease (enda). (177 aa) |
| | SSO0280 | Hypothetical protein; Similar to S. shibatae YTF2_SULSH (P46221) protein in TF55 5' region. (170 aa) |
| | hisS | Histidyl-tRNA synthetase (hisS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-II aminoacyl-tRNA synthetase family. (426 aa) |
| | SSO0276 | Hypothetical protein. (146 aa) |
| | tgtA | Queuine/archaeosine-tRNA -ribosyltransferase (tgtA); Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (503 aa) |
| | SSO0267 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (160 aa) |
| | tfE | Transcription Factor E (TFE), TFIIE alpha subunit homolog (tfE); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and d [...] (178 aa) |
| | SSO0260 | Conserved hypothetical protein. (107 aa) |
| | tiaS | Conserved hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (443 aa) |
| | SSO0252 | Proliferating-cell nucleolar antigen p120 homolog; FMU/NOL1/NOP2 family protein; Cellular Processes. (339 aa) |
| | gatB-1 | Glutamyl-tRNA -Gln amidotransferase, subunit B (gatB-1); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity); Belongs to the GatB/GatE family. GatB subfamily. (458 aa) |
| | rpoB1 | DNA-directed RNA polymerase, subunit B' (rpoB1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (649 aa) |
| | rpoA1 | DNA-directed RNA polymerase, subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (880 aa) |
| | rpoA2 | DNA-directed RNA polymerase, subunit A'' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (395 aa) |
| | nusA | Transcription termination factor nusA homolog, putative (nusA); Participates in transcription termination. Belongs to the NusA family. (124 aa) |
| | rad2 | DNA repair endo/exonuclease FEN-1 (RAD2) (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base exci [...] (302 aa) |
| | truD | Conserved hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (377 aa) |
| | aspS | Aspartyl-tRNA synthetase (aspS); Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (429 aa) |
| | SSO0172 | Conserved hypothetical protein. (170 aa) |
| | rps8E | LSU ribosomal protein S8E (rps8E); Translation, Ribosomal Proteins. (133 aa) |
| | SSO0140 | Primase (Carboxy-end fragment); Encoded by Sulfolobus plasmids; Replication and Repair. (532 aa) |
| | sun-2 | NOL1/NOP2/sun family protein. Related to eucaryotic proliferating-cell nucleolar protein p120; Cellular Processes. (368 aa) |
| | pheT | Phenylalanyl-tRNA synthetase beta subunit (pheT); Translation, Aminoacyl tRNA synthetases. (544 aa) |
| | pheS | Phenylalanyl-tRNA synthetase alpha subunit (pheS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (468 aa) |
| | gltX | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (575 aa) |
| | rpl7AE | LSU ribosomal protein L7AE (rpl7AE); Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs; Belongs to the eukaryotic ribosomal protein eL8 family. (130 aa) |
| | lysS | Lysyl-tRNA synthetase (lysS); Translation, Aminoacyl tRNA synthetases. (494 aa) |
| | pelA | Cell division protein pelota homolog (pelA); May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (344 aa) |
| | dnaG | Bacterial-like DNA primase (dnaG); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Can use NTPs but not dNTPs. Binds DNA. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine- rich transcripts and the exosome. Belongs to the archaeal DnaG primase family. (406 aa) |
| | tyrS | Tyrosyl-tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (366 aa) |
| | rps11AB | SSU ribosomal protein S11AB (rps11AB); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (132 aa) |
| | rpoD | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (265 aa) |
| | rps9AB | SSU ribosomal protein S9AB (rps9AB); Translation, Ribosomal Proteins; Belongs to the universal ribosomal protein uS9 family. (140 aa) |
| | SSO0006 | Conserved hypothetical protein; Present in archaea and some bacteria and eukarya, including M. jannaschii, E. coli, B. subtilus, yeast, and human. (228 aa) |
