(16 nodes) Ribonucleoprotein complex assembly network (Saccharolobus solfataricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rps2AB	SSU ribosomal protein S2AB (rps2AB); Translation, Ribosomal Proteins; Belongs to the universal ribosomal protein uS2 family. (231 aa)
	rps11AB	SSU ribosomal protein S11AB (rps11AB); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (132 aa)
	rpS7AB	SSU ribosomal protein S7AB (rpS7AB); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (193 aa)
	SSO0276	Hypothetical protein. (146 aa)
	rpl10E	LSU ribosomal protein L10E (rpl10E); Translation, Ribosomal Proteins; Belongs to the universal ribosomal protein uL16 family. (178 aa)
	rplp0	LSU acidic ribosomal protein P0 homolog (rplp0); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. (338 aa)
	eiF6	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family. (223 aa)
	eif2G	Translation initiation factor eiF 2 gamma (eif2G); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. (415 aa)
	rpl18AB	LSU ribosomal protein L18AB (rpl18AB); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (199 aa)
	rps19AB	SSU ribosomal protein S19AB (rps19AB); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa)
	SSO10051	Conserved hypothetical protein; Similarity with APE1091, PH1323, PAB1812, AF2070. (89 aa)
	eif2B	Translation initiation factor 2, beta subunit (eif2B); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (139 aa)
	SSO3240	Conserved hypothetical protein. (152 aa)
	rps28E	SSU ribosomal protein S28E (rps28E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS28 family. (98 aa)
	rpl23AB	LSU ribosomal protein L23AB (rpl23AB); Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (81 aa)
	rps27E	SSU ribosomal protein S27E (rps27E); Translation, Ribosomal Proteins. (66 aa)

Your Current Organism:

Saccharolobus solfataricus

NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SSO0276	eiF6	SSO0276	SSO0351	Hypothetical protein.	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	0.439
SSO0276	rpS7AB	SSO0276	SSO0217	Hypothetical protein.	SSU ribosomal protein S7AB (rpS7AB); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.	0.491
SSO0276	rps28E	SSO0276	SSO5479	Hypothetical protein.	SSU ribosomal protein S28E (rps28E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS28 family.	0.682
SSO0276	rps2AB	SSO0276	SSO0067	Hypothetical protein.	SSU ribosomal protein S2AB (rps2AB); Translation, Ribosomal Proteins; Belongs to the universal ribosomal protein uS2 family.	0.418
SSO3240	rpS7AB	SSO3240	SSO0217	Conserved hypothetical protein.	SSU ribosomal protein S7AB (rpS7AB); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.	0.524
SSO3240	rps11AB	SSO3240	SSO0072	Conserved hypothetical protein.	SSU ribosomal protein S11AB (rps11AB); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.	0.691
SSO3240	rps19AB	SSO3240	SSO0715	Conserved hypothetical protein.	SSU ribosomal protein S19AB (rps19AB); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.702
SSO3240	rps28E	SSO3240	SSO5479	Conserved hypothetical protein.	SSU ribosomal protein S28E (rps28E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS28 family.	0.743
SSO3240	rps2AB	SSO3240	SSO0067	Conserved hypothetical protein.	SSU ribosomal protein S2AB (rps2AB); Translation, Ribosomal Proteins; Belongs to the universal ribosomal protein uS2 family.	0.712
eiF6	SSO0276	SSO0351	SSO0276	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	Hypothetical protein.	0.439
eiF6	eif2B	SSO0351	SSO2381	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	Translation initiation factor 2, beta subunit (eif2B); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.	0.777
eiF6	eif2G	SSO0351	SSO0412	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	Translation initiation factor eiF 2 gamma (eif2G); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.	0.930
eiF6	rpS7AB	SSO0351	SSO0217	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	SSU ribosomal protein S7AB (rpS7AB); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.	0.707
eiF6	rpl10E	SSO0351	SSO0294	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	LSU ribosomal protein L10E (rpl10E); Translation, Ribosomal Proteins; Belongs to the universal ribosomal protein uL16 family.	0.998
eiF6	rpl18AB	SSO0351	SSO0699	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	LSU ribosomal protein L18AB (rpl18AB); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	0.986
eiF6	rpl23AB	SSO0351	SSO6401	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	LSU ribosomal protein L23AB (rpl23AB); Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.	0.994
eiF6	rplp0	SSO0351	SSO0344	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	LSU acidic ribosomal protein P0 homolog (rplp0); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.	0.986
eiF6	rps11AB	SSO0351	SSO0072	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	SSU ribosomal protein S11AB (rps11AB); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.	0.543
eiF6	rps19AB	SSO0351	SSO0715	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	SSU ribosomal protein S19AB (rps19AB); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.634
eiF6	rps28E	SSO0351	SSO5479	Translation initiation factor 6 (eiF 6) (eiF6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. Inhibits translation of both leadered and leaderless mRNAs, maybe by binding to the 50S ribosome subunit, preventing it from binding to the 30S subunit; Belongs to the eIF-6 family.	SSU ribosomal protein S28E (rps28E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS28 family.	0.591