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fumC fumC AcnA AcnA porD-2 porD-2 pdhD-1 pdhD-1 porB-1 porB-1 porG-1 porG-1 pdhD-2 pdhD-2 pdhC pdhC pdhD-3 pdhD-3 porD-like porD-like porA-like porA-like porB-like porB-like idh idh sdhA sdhA sdhB sdhB sdhC sdhC sdhD sdhD sucD sucD pckG pckG pdhD-4 pdhD-4 sqdB-2 sqdB-2 gltA gltA porB-2 porB-2 porA-2 porA-2 porG-2 porG-2 SSO2815 SSO2815 SSO2816 SSO2816 porD-1 porD-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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fumCFumarate hydratase classe II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate. (445 aa)
AcnAAconitate hydratase; Energy Metabolism, Tri-Carboxylic Acid Cycle. (855 aa)
porD-2Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-2); Energy Metabolism. (94 aa)
pdhD-1Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (446 aa)
porB-1Pyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (porB-1); Energy Metabolism. (300 aa)
porG-1Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (porG-1); Energy Metabolism. (190 aa)
pdhD-2Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (412 aa)
pdhCDihydrolipoamide S-acetyltransferase, amino-end (pdhC); Probable frameshift with SSO1530; Energy Metabolism. (211 aa)
pdhD-3Dihydrolipoamide dehydrogenase (pdhD-3); Highest hit with Thermoplasma; Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (456 aa)
porD-likePyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-like); Contains long amino-end extension, only present in M. thermoautrophicum MTH1740 gene; Energy Metabolism. (363 aa)
porA-likePyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-like); Energy Metabolism. (415 aa)
porB-likePyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (porB-like); Energy Metabolism. (338 aa)
idhIsocitrate dehydrogenase, probable (idh); Energy Metabolism, Tri-Carboxylic Acid Cycle. (413 aa)
sdhASuccinate dehydrogenase subunit A (sdhA); Flavoprotein subunit; Energy Metabolism, Electron transport. (566 aa)
sdhBSuccinate dehydrogenase subunit B (sdhB); Iron-sulfur subunit B; Energy Metabolism, Electron transport. (316 aa)
sdhCSuccinate dehydrogenase subunit C (sdhC); Iron-sulfur subunit C; also hit with htrB2 subunit of heterodisulfide reductase; Energy Metabolism, Electron transport. (293 aa)
sdhDSuccinate dehydrogenase subunit D (sdhD); Subunit D; Energy Metabolism, Electron transport. (121 aa)
sucDSuccinyl-CoA synthetase, alpha subunit (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (260 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (603 aa)
pdhD-4Dihydrolipoamide dehydrogenase (pdhD-4); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (409 aa)
sqdB-2L-lactate dehydrogenase (sqdB); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (327 aa)
gltACitrate synthase; Energy Metabolism; Belongs to the citrate synthase family. (377 aa)
porB-2Pyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (porB-2); Energy Metabolism. (299 aa)
porA-2Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-2); Energy Metabolism. (400 aa)
porG-2Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (porG-2); Energy Metabolism. (184 aa)
SSO28152-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism. (632 aa)
SSO28162-oxoacid--ferredoxin oxidoreductase, beta chain; Energy Metabolism. (316 aa)
porD-1Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-1); Energy Metabolism. (88 aa)
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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