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SSO0094 SSO0094 glnA-1 glnA-1 glyA glyA SSO0666 SSO0666 gcvPB gcvPB gcvPA gcvPA GcvT GcvT gcvH1 gcvH1 fdhF-1 fdhF-1 gcvH2 gcvH2 AcnA AcnA gcvH3 gcvH3 pdhD-1 pdhD-1 SSO1154 SSO1154 pdhD-2 pdhD-2 pdhD-3 pdhD-3 acsA-5 acsA-5 acaB-2 acaB-2 acaB-3 acaB-3 acsA-7 acsA-7 acsA-8 acsA-8 mcmA2 mcmA2 acaB-4 acaB-4 mcmA1 mcmA1 Mce Mce glnA-2 glnA-2 ppcB ppcB pdhD-4 pdhD-4 sqdB-2 sqdB-2 gltA gltA acaB-7 acaB-7 fdhF-2 fdhF-2 acsA-9 acsA-9 acaB-9 acaB-9 SSO3071 SSO3071 glcD glcD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SSO0094Conserved hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate. (228 aa)
glnA-1Glutamine synthetase (glutamate ammonia ligase) (GS). (glnA-1); Amino Acid Biosynthesis, Glutamate. (471 aa)
glyASerine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with the modified folate sulfopterin serving as the one-carbon carrier. Cannot use tetrahydrofolate (THF or H4PteGlu) as the pteridine substrate. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of both allo-threonine and beta-phenylserine. (433 aa)
SSO0666Glycerate kinase, putative; Uncategorized. (400 aa)
gcvPBGlycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (508 aa)
gcvPAGlycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (455 aa)
GcvTAminomethyltransferase; Energy Metabolism. (346 aa)
gcvH1Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (137 aa)
fdhF-1Formate dehydrogenase Alpha subunit (fdhF-1); Energy Metabolism. (657 aa)
gcvH2Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (148 aa)
AcnAAconitate hydratase; Energy Metabolism, Tri-Carboxylic Acid Cycle. (855 aa)
gcvH3Glycine cleavage system protein H, hypothetical; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (140 aa)
pdhD-1Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (446 aa)
SSO1154Monoamine oxidase regulatory protein; Uncategorized. (163 aa)
pdhD-2Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (412 aa)
pdhD-3Dihydrolipoamide dehydrogenase (pdhD-3); Highest hit with Thermoplasma; Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (456 aa)
acsA-5Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-5); Lipid metabolism. (498 aa)
acaB-2Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-2); Lipid metabolism. (381 aa)
acaB-3Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-3); Lipid metabolism. (409 aa)
acsA-7Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-7); Lipid metabolism. (608 aa)
acsA-8Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-8); Lipid metabolism. (571 aa)
mcmA2Methylmalonyl-CoA mutase, alpha-subunit, chain B (mcmA2); Cellular Processes, Detoxification. (141 aa)
acaB-4Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-4); Lipid metabolism. (397 aa)
mcmA1Methylmalonyl-CoA mutase, alpha-subunit, chain A (mcmA1); Highly conserved with Pyrococcus and Archaeoglobus; Cellular Processes, Detoxification. (561 aa)
MceLactoylglutathione lyase (glyoxalase I), putative; Energy Metabolism. (142 aa)
glnA-2Glutamine synthetase (glutamate ammonia ligase) (GS). (glnA-2); Amino Acid Biosynthesis, Glutamate; Belongs to the glutamine synthetase family. (425 aa)
ppcBPropionyl-CoA carboxylase beta subunit (ppcB); Lipid metabolism. (523 aa)
pdhD-4Dihydrolipoamide dehydrogenase (pdhD-4); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (409 aa)
sqdB-2L-lactate dehydrogenase (sqdB); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (327 aa)
gltACitrate synthase; Energy Metabolism; Belongs to the citrate synthase family. (377 aa)
acaB-7Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-7); Lipid metabolism. (387 aa)
fdhF-2Formate dehydrogenase Alpha subunit (fdhF-2); Energy Metabolism. (979 aa)
acsA-9Acetyl-CoA synthetase (acetate-CoA ligase) (acsA-9); Lipid metabolism. (666 aa)
acaB-9Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-9); Lipid metabolism. (395 aa)
SSO3071Conserved hypothetical protein. (243 aa)
glcDGlycolate oxidase glcD subunit. (glcD); Energy Metabolism. (467 aa)
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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