(33 nodes) Butanoate metabolism network (Saccharolobus solfataricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SSO0535	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa)
	ilvB-2	Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate. (572 aa)
	gctA	Glutaconate CoA-transferase, subunit A (gctA); Energy Metabolism. (268 aa)
	gctB	Glutaconate CoA-transferase, subunit B (gctB); Energy Metabolism. (245 aa)
	porD-2	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-2); Energy Metabolism. (94 aa)
	SSO1154	Monoamine oxidase regulatory protein; Uncategorized. (163 aa)
	porB-1	Pyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (porB-1); Energy Metabolism. (300 aa)
	porG-1	Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (porG-1); Energy Metabolism. (190 aa)
	acaB-2	Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-2); Lipid metabolism. (381 aa)
	acaB-3	Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-3); Lipid metabolism. (409 aa)
	porD-like	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-like); Contains long amino-end extension, only present in M. thermoautrophicum MTH1740 gene; Energy Metabolism. (363 aa)
	porA-like	Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-like); Energy Metabolism. (415 aa)
	porB-like	Pyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (porB-like); Energy Metabolism. (338 aa)
	sdhA	Succinate dehydrogenase subunit A (sdhA); Flavoprotein subunit; Energy Metabolism, Electron transport. (566 aa)
	sdhB	Succinate dehydrogenase subunit B (sdhB); Iron-sulfur subunit B; Energy Metabolism, Electron transport. (316 aa)
	sdhC	Succinate dehydrogenase subunit C (sdhC); Iron-sulfur subunit C; also hit with htrB2 subunit of heterodisulfide reductase; Energy Metabolism, Electron transport. (293 aa)
	sdhD	Succinate dehydrogenase subunit D (sdhD); Subunit D; Energy Metabolism, Electron transport. (121 aa)
	acaB-4	Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-4); Lipid metabolism. (397 aa)
	paaF-7	Enoyl CoA hydratase (paaF-7); Lipid metabolism; Belongs to the enoyl-CoA hydratase/isomerase family. (266 aa)
	acaB-7	Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-7); Lipid metabolism. (387 aa)
	adh-11	Alcohol dehydrogenase (Zn containing) (adh-11); Energy Metabolism. (317 aa)
	abfD-2	4-hydroxybutyryl-CoA dehydratase (abfD-2); Amino Acid Biosynthesis. (502 aa)
	porB-2	Pyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (porB-2); Energy Metabolism. (299 aa)
	porA-2	Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-2); Energy Metabolism. (400 aa)
	porG-2	Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (porG-2); Energy Metabolism. (184 aa)
	SSO2815	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism. (632 aa)
	SSO2816	2-oxoacid--ferredoxin oxidoreductase, beta chain; Energy Metabolism. (316 aa)
	acaB-9	Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-9); Lipid metabolism. (395 aa)
	maiA	Maleate cis-trans isomerase, probable (maiA); Cofactor Biosynthesis. (242 aa)
	hdb-3	3-hydroxyacyl-CoA dehydrogenase (hdb-3); Lipid metabolism. (384 aa)
	ilvB-6	Acetolactate synthase large subunit homolog (ilvB-6); Amino Acid Biosynthesis, Pyruvate. (543 aa)
	gabT-2	4-aminobutyrate aminotransferase (gabT-2); Amino Acid Biosynthesis; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
	porD-1	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-1); Energy Metabolism. (88 aa)

Your Current Organism:

Saccharolobus solfataricus

NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SSO0535	SSO2815	SSO0535	SSO2815	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.	0.900
SSO0535	SSO2816	SSO0535	SSO2816	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	2-oxoacid--ferredoxin oxidoreductase, beta chain; Energy Metabolism.	0.907
SSO0535	acaB-2	SSO0535	SSO2061	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-2); Lipid metabolism.	0.993
SSO0535	acaB-3	SSO0535	SSO2062	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-3); Lipid metabolism.	0.993
SSO0535	acaB-4	SSO0535	SSO2377	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-4); Lipid metabolism.	0.991
SSO0535	acaB-7	SSO0535	SSO2625	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-7); Lipid metabolism.	0.994
SSO0535	acaB-9	SSO0535	SSO2874	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-9); Lipid metabolism.	0.994
SSO0535	hdb-3	SSO0535	SSO2996	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	3-hydroxyacyl-CoA dehydrogenase (hdb-3); Lipid metabolism.	0.903
SSO0535	porA-2	SSO0535	SSO2757	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-2); Energy Metabolism.	0.900
SSO0535	porA-like	SSO0535	SSO2129	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-like); Energy Metabolism.	0.900
SSO0535	porB-1	SSO0535	SSO1206	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (porB-1); Energy Metabolism.	0.907
SSO0535	porB-2	SSO0535	SSO2756	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (porB-2); Energy Metabolism.	0.907
SSO0535	porB-like	SSO0535	SSO2130	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (porB-like); Energy Metabolism.	0.907
SSO0535	porD-1	SSO0535	SSO7412	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-1); Energy Metabolism.	0.900
SSO0535	porD-2	SSO0535	SSO11071	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-2); Energy Metabolism.	0.900
SSO0535	porD-like	SSO0535	SSO2128	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (porD-like); Contains long amino-end extension, only present in M. thermoautrophicum MTH1740 gene; Energy Metabolism.	0.900
SSO0535	porG-1	SSO0535	SSO1208	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (porG-1); Energy Metabolism.	0.912
SSO0535	porG-2	SSO0535	SSO2758	Acyl carrier protein synthase; Lipid metabolism; Belongs to the thiolase-like superfamily. UPF0219 family.	Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (porG-2); Energy Metabolism.	0.912
SSO1154	abfD-2	SSO1154	SSO2738	Monoamine oxidase regulatory protein; Uncategorized.	4-hydroxybutyryl-CoA dehydratase (abfD-2); Amino Acid Biosynthesis.	0.907
SSO1154	acaB-2	SSO1154	SSO2061	Monoamine oxidase regulatory protein; Uncategorized.	Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-2); Lipid metabolism.	0.549