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rpl40e rpl40e rps10p rps10p rps12p rps12p rpl30e rpl30e aif2/5b aif2/5b rpl24e rpl24e rps25e rps25e rpl14e rpl14e rpl34e rpl34e rpl30p rpl30p rps5p rps5p rpl18p rpl18p rpl19e rpl19e rpl32e rpl32e rpl6p rpl6p rps8p rps8p rps14p rps14p rpl5p rpl5p rps4e rps4e rpl14p rpl14p rpl29p rpl29p rpl22p rpl22p rps19p rps19p rpl2p rpl2p rpl23p rpl23p fusA fusA rpl37ae rpl37ae rpl21e rpl21e aif1a aif1a rpl44e rpl44e rpl12p rpl12p rplP0 rplP0 rpl1p rpl1p rpl11p rpl11p rps19e rps19e rpls26e rpls26e rps2p rps2p rpl13p rpl13p
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl40e50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (56 aa)
rps10p30S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rps12p30S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa)
rpl30e50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (106 aa)
aif2/5bTranslation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (602 aa)
rpl24e50S ribosomal protein L24e; Binds to the 23S rRNA. (61 aa)
rps25e30S ribosomal protein S25e; Belongs to the eukaryotic ribosomal protein eS25 family. (109 aa)
rpl14e50S ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family. (96 aa)
rpl34e50S ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (87 aa)
rpl30p50S ribosomal protein L30P. (158 aa)
rps5p30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (214 aa)
rpl18p50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (196 aa)
rpl19e50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (151 aa)
rpl32e50S ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. (131 aa)
rpl6p50S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (186 aa)
rps8p30S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa)
rps14p30S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (54 aa)
rpl5p50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (177 aa)
rps4e30S ribosomal protein S4e; N-term changed (+195); Belongs to the eukaryotic ribosomal protein eS4 family. (243 aa)
rpl14p50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (138 aa)
rpl29p50S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (88 aa)
rpl22p50S ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (156 aa)
rps19p30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa)
rpl2p50S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa)
rpl23p50S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (82 aa)
fusAElongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (737 aa)
rpl37ae50S ribosomal protein L37Ae; Binds to the 23S rRNA. (70 aa)
rpl21e50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (103 aa)
aif1aTranslation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). (108 aa)
rpl44e50S ribosomal protein L44e; Binds to the 23S rRNA. (95 aa)
rpl12p50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (105 aa)
rplP050S ribosomal protein P0; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (334 aa)
rpl1p50S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (219 aa)
rpl11p50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (170 aa)
rps19e30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (153 aa)
rpls26e30S ribosomal protein S26e; N-term changed (+120). (95 aa)
rps2p30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (225 aa)
rpl13p50S ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (146 aa)
Your Current Organism:
Sulfurisphaera tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii str. 7, Sulfurisphaera tokodaii str. 7, Sulfurisphaera tokodaii strain 7
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