STRINGSTRING
acsA acsA ST0114 ST0114 ST0278 ST0278 sdhA sdhA shdB shdB sdhC sdhC sdhD sdhD gltA gltA ST0619 ST0619 ST0730 ST0730 citB citB sucD sucD sucC sucC pckG pckG ST1190 ST1190 acyP acyP ppsA ppsA ilvB ilvB ST1531 ST1531 STK_15315 STK_15315 ST1532 ST1532 ST1533 ST1533 ST1537 ST1537 pyk pyk ST1787 ST1787 ST1788 ST1788 STK_17884 STK_17884 STK_17887 STK_17887 ST1803 ST1803 gltA-2 gltA-2 mdh mdh ST2019 ST2019 fumC fumC ppc ppc ST2139 ST2139 idh idh ST2298 ST2298 ST2300 ST2300 ST2410 ST2410 ST2433 ST2433 ST2435 ST2435 ST2575 ST2575
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acsAacetyl-CoA synthetase. (562 aa)
ST0114Malate dehydrogenase; Protein synonym:NADP(+)-dependent malic enzyme. (414 aa)
ST0278Malate dehydrogenase; N-term changed (-51); protein synonym:NADP(+)-dependent malic enzyme. (426 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Protein synonym:succinate--caldariellaquinone oxidoreductase. (566 aa)
shdBSuccinate dehydrogenase iron-sulfur protein subunit; Protein synonym:succinate--caldariellaquinone oxidoreductase. (320 aa)
sdhCSuccinate dehydrogenase subunit SdhC; Protein synonym:CCG-domain-containing subunit SdhE; protein synonym:succinate--caldariellaquinone oxidoreductase. (290 aa)
sdhDSuccinate dehydrogenase subunit SdhD; Protein synonym:succinate--caldariellaquinone oxidoreductase. (116 aa)
gltACitrate synthase. (373 aa)
ST0619Putative 3-hydroxyisobutyrate dehydrogenase. (291 aa)
ST0730acyl-CoA synthetase. (662 aa)
citBAconitate hydratase; Protein synonym:aconitase. (855 aa)
sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (259 aa)
sucCsuccinyl-CoA synthetase beta subunit; N-term changed (+195); N-terminus of this ORF was identified by Edman sequencing; protein synonym:succinate---CoA ligase. (337 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (602 aa)
ST1190Putative acyl-CoA synthetase. (497 aa)
acyPAcylphosphatase. (90 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (784 aa)
ilvBAcetolactate synthase. (572 aa)
ST15312-oxoacid--ferredoxin oxidoreductase gamma subunit. (181 aa)
STK_153152-oxoacid--ferredoxin oxidoreductase delta subunit. (88 aa)
ST15322-oxoacid--ferredoxin oxidoreductase alpha subunit. (386 aa)
ST15332-oxoacid--ferredoxin oxidoreductase beta subunit; N-term changed (-9). (297 aa)
ST1537ADP-forming acetyl-CoA synthetase. (659 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (438 aa)
ST17872-oxoacid--ferredoxin oxidoreductase beta subunit; N-term changed (-15). (301 aa)
ST17882-oxoacid--ferredoxin oxidoreductase alpha subunit. (398 aa)
STK_178842-oxoacid--ferredoxin oxidoreductase delta subunit. (87 aa)
STK_178872-oxoacid--ferredoxin oxidoreductase gamma subunit; N-term changed (+273). (184 aa)
ST1803Putative acetyl-CoA synthetase. (621 aa)
gltA-2Citrate synthase. (378 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (308 aa)
ST2019acyl-CoA synthetase. (661 aa)
fumCFumarate hydratase; N-term changed (-3); protein synonym:fumarase C. (438 aa)
ppcPhosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (511 aa)
ST2139Putative acetyl-CoA synthetase; N-term changed (-33). (565 aa)
idhIsocitrate dehydrogenase. (409 aa)
ST22982-oxoacid--ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives. (305 aa)
ST23002-oxoacid--ferredoxin oxidoreductase alpha subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives. (627 aa)
ST2410Hypothetical protein. (531 aa)
ST24332-oxoacid--ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives. (304 aa)
ST24352-oxoacid--ferredoxin oxidoreductase alpha subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives. (628 aa)
ST2575Putative acyl-CoA synthetase. (544 aa)
Your Current Organism:
Sulfurisphaera tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii str. 7, Sulfurisphaera tokodaii str. 7, Sulfurisphaera tokodaii strain 7
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