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| | ST1802 | Putative acyl-CoA dehydrogenase. (374 aa) |
| | ST1800 | Hypothetical protein. (369 aa) |
| | ST1799 | Putative acyl-CoA acyltransferase. (391 aa) |
| | ST1796 | Putative acetyl-CoA synthetase. (609 aa) |
| | ST1791 | Putative acyl-CoA dehydrogenase; N-term changed (-15). (399 aa) |
| | STK_17887 | 2-oxoacid--ferredoxin oxidoreductase gamma subunit; N-term changed (+273). (184 aa) |
| | STK_17884 | 2-oxoacid--ferredoxin oxidoreductase delta subunit. (87 aa) |
| | mcl | Putative malyl-CoA lyase; N-term changed (+42). (266 aa) |
| | cysA | Probable thiosulfate sulfurtransferase; Protein synonym:rhodanese. (267 aa) |
| | ST1705 | Putative isomerase/decarboxylase; N-terminus of this ORF was identified by Edman sequencing. (281 aa) |
| | ST1659 | 4-hydroxybutyryl-CoA dehydratase. (502 aa) |
| | ST1655 | Hypothetical protein. (383 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (438 aa) |
| | ST1580 | Putative prolidase. (394 aa) |
| | trpB-2 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (449 aa) |
| | ST1548 | Putative hydrolase. (194 aa) |
| | STK_15315 | 2-oxoacid--ferredoxin oxidoreductase delta subunit. (88 aa) |
| | ST1531 | 2-oxoacid--ferredoxin oxidoreductase gamma subunit. (181 aa) |
| | argE-2 | Putative acetylornithine deacetylase. (382 aa) |
| | ST1520 | Hypothetical protein. (223 aa) |
| | hom | Homoserine dehydrogenase; N-term changed (-24). (304 aa) |
| | ST1516 | 3-hydroxypropionyl-CoA dehydratase; N-term changed (-36); N-terminus of this ORF was identified by Edman sequencing; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | ST1508 | Hypothetical protein. (187 aa) |
| | ST1507 | Malonate-semialdehyde reductase; Protein synonym:3-hydroxypropionate dehydrogenase. (318 aa) |
| | argE | Putative acetylornithine deacetylase; Catalyzes the ATP-dependent formation of a covalent bond between the amino group of glutamate and the gamma-carboxyl group of the C-terminal glutamate residue in LysW. Belongs to the RimK family. LysX subfamily. (282 aa) |
| | carB | Carbamoyl-phosphate synthase large chain. (1049 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (372 aa) |
| | argH | Argininosuccinate lyase; Protein synonym:arginosuccinase. (446 aa) |
| | argG | Argininosuccinate synthase; Protein synonym:citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (390 aa) |
| | ST1497 | Putative amidophosphoribosyltransferase; Protein synonym:glutamine phosphoribosylpyrophosphate amidotransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (403 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (443 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa) |
| | ST1492 | tRNA-binding protein. (113 aa) |
| | pyrB | Aspartate carbamoyltransferase. (298 aa) |
| | lrp | Leucine-responsive-regulatory protein Lrp; N-term changed (-9). (155 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (453 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (118 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase; N-term changed (-42). (94 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (394 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). (249 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (194 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase. (230 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (285 aa) |
| | hisC | Histidinol-phosphate aminotransferase; N-term changed (+213). (357 aa) |
| | leuS-2 | leucyl-tRNA synthetase; Protein synonym:leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (894 aa) |
| | ilvB | Acetolactate synthase. (572 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa) |
| | pdxT | Pyridoxal 5'-phosphate biosynthesis protein PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (200 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (483 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. (571 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (566 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha chain; Protein synonym:phenylalanine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (469 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta chain; Protein synonym:phenylalanine--tRNA ligase. (540 aa) |
| | ST1411 | Protein synonym:alpha-aminotransferase. (400 aa) |
| | ST1402 | Hypothetical protein. (189 aa) |
| | glnA | Glutamine synthetase; Protein synonym:glutamate--ammonia ligase; Belongs to the glutamine synthetase family. (473 aa) |
| | cysM | Cysteine synthase; Protein synonym:O-acetylserine sulfhydrylase. (300 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (904 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa) |
| | ST0552 | methylmalonyl-CoA mutase large subunit. (562 aa) |
| | ST0568 | Putative glutamine synthetase; Protein synonym:glutamate--ammonia ligase; Belongs to the glutamine synthetase family. (429 aa) |
| | ST0574 | Putative sugar kinase. (285 aa) |
| | guaAA | GMP synthase [glutamine-hydrolyzing] subunit A; Catalyzes the synthesis of GMP from XMP. (188 aa) |
| | pccB | acetyl-CoA/propionyl-CoA carboxylase gamma subunit; N-term changed (-6); protein synonym:carboxyltransferase. (521 aa) |
| | accB | acetyl-CoA/propionyl-CoA carboxylase beta subunit; N-term changed (-6); N-terminus of this ORF was identified by Edman sequencing; protein synonym:biotin carboxyl carrier protein. (167 aa) |
| | lysU/leuC | Homoaconitase/3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (415 aa) |
| | lysT/leuD | Homoaconitase/3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (168 aa) |
| | ST0602 | Aminotransferase; N-terminus of this ORF was identified by Edman sequencing. (389 aa) |
| | ST0610 | Putative enoyl-CoA hydratase. (252 aa) |
| | ST0618 | Hypothetical protein. (466 aa) |
| | leuS | leucyl-tRNA synthetase; Protein synonym:leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (945 aa) |
| | ST0627 | Putative peptidase M20 family protein. (422 aa) |
| | ST0632 | Hypothetical protein; N-term changed (-3). (227 aa) |
| | ST0639 | Hypothetical protein. (583 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (259 aa) |
| | dld | D-lactate dehydrogenase. (440 aa) |
| | ST0655 | Hypothetical protein. (280 aa) |
| | ST0675 | Hypothetical protein. (188 aa) |
| | pheA1 | Putative phenol hydroxylase large component. (494 aa) |
| | ST0727 | Putative isomerase/decarboxylase; N-term changed (-12). (289 aa) |
| | ST0730 | acyl-CoA synthetase. (662 aa) |
| | iorB | Indolepyruvate--ferredoxin oxidoreductase beta subunit. (186 aa) |
| | gabT | Putative 4-aminobutyrate aminotransferase; Protein synonym:GABA transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (419 aa) |
| | STK_07830 | 3-hydroxypropionyl-CoA synthetase; Plays a role in the autotrophic CO(2) fixation pathway. Activates 3-hydroxypropionate to its CoA ester. Can also activate propionate, and to a lesser extent acrylate, acetate and butyrate. (659 aa) |
| | ST0862 | Hypothetical protein. (216 aa) |
| | ST0874 | Hypothetical protein. (206 aa) |
| | ST0916 | Putative acyl-CoA dehydrogenase. (358 aa) |
| | mtnA | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (362 aa) |
| | ST0938 | Oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa) |
| | ST0960 | Putative threonine synthase. (337 aa) |
| | thrS1 | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr) but cannot deacylate incorrectly charged amino acid; unlike most archaea the editing function is found in a freestanding protein. (540 aa) |
| | grp | Glutamine receptor protein; Protein synonym:Lrp family transcriptional regulator. (150 aa) |
| | arcA | Arginine deiminase. (378 aa) |
| | ST1110 | Hypothetical protein. (386 aa) |
| | fadD | long-chain-fatty-acid--CoA ligase; Protein synonym:acyl-CoA synthetase. (504 aa) |
| | ST1113 | Putative peptidase M20 family protein. (426 aa) |
| | ST1114 | Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa) |
| | ST1115 | Putative Lrp family transcriptional regulator. (151 aa) |
| | ST1134 | Muconolactone delta-isomerase family protein. (103 aa) |
| | ST1190 | Putative acyl-CoA synthetase. (497 aa) |
| | nadA | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (308 aa) |
| | gcvH | Glycine cleavage system H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (139 aa) |
| | gcvT | Glycine cleavage system T-protein; Protein synonym:aminomethyltransferase. (346 aa) |
| | gcvPA | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (449 aa) |
| | gcvPB | Glycine cleavage system P-protein subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (505 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (416 aa) |
| | serC | Phosphoserine aminotransferase; Protein synonym:3-phosphohydroxypyruvate transaminase. (372 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (809 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (246 aa) |
| | trpG | Anthranilate synthase component II. (193 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (433 aa) |
| | trpF | N- (5'-phosphoribosyl) anthranilate isomerase; N-term changed (+165); Belongs to the TrpF family. (200 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (345 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (245 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (422 aa) |
| | ppsA | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (784 aa) |
| | thrC | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (395 aa) |
| | lysC | Protein synonym:aspartokinase; Belongs to the aspartokinase family. (447 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase. (350 aa) |
| | argF | Putative ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (306 aa) |
| | argS | arginyl-tRNA synthetase; Protein synonym:arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (623 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase subunit GatD; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (448 aa) |
| | ST1273 | Hypothetical protein. (311 aa) |
| | STK_13010 | Homocitrate synthase; Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway. Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily. (460 aa) |
| | STK_13480 | Arginine decarboxylase proenzyme; Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (128 aa) |
| | STK_13490 | Protein synonym:HMG-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (348 aa) |
| | ST1350 | Putative acyl-CoA acyltransferase. (363 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (433 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase. (343 aa) |
| | ST2620 | Putative hydrolase. (220 aa) |
| | ST2575 | Putative acyl-CoA synthetase. (544 aa) |
| | ST2570 | L-2-haloacid dehalogenase. (201 aa) |
| | cysA-2 | Probable thiosulfate sulfurtransferase; Protein synonym:rhodanese. (293 aa) |
| | ST2560 | Probable sulfolactate sulfo-lyase large subunit. (387 aa) |
| | ST2559 | Probable sulfolactate sulfo-lyase small subunit; N-term changed (-45). (98 aa) |
| | ST2555 | Regucalcin homolog. (285 aa) |
| | argE-3 | Putative acetylornithine deacetylase. (374 aa) |
| | ST2545 | Putative glucosamine--fructose-6-phosphate aminotransferase; Protein synonym:glucosamine 6-phosphate synthase. (581 aa) |
| | ST2507 | Creatininase family protein; N-term changed (-12). (227 aa) |
| | ST2441 | Putative hydrolase. (338 aa) |
| | ST2435 | 2-oxoacid--ferredoxin oxidoreductase alpha subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives. (628 aa) |
| | ST2433 | 2-oxoacid--ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives. (304 aa) |
| | ST2420 | phenylacetate--CoA ligase; N-terminus of this ORF was identified by Edman sequencing. (429 aa) |
| | ST2418 | Putative acyl-CoA acyltransferase. (387 aa) |
| | ST2417 | Putative enoyl-CoA hydratase; N-terminus of this ORF was identified by Edman sequencing; Belongs to the enoyl-CoA hydratase/isomerase family. (250 aa) |
| | ST2416 | enoyl-CoA hydratase; N-term changed (-9); N-terminus of this ORF was identified by Edman sequencing; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa) |
| | ST2413 | 3-hydroxyacyl-CoA dehydrogenase. (278 aa) |
| | STK_24125 | Hypothetical protein. (53 aa) |
| | ST0048 | enoyl-CoA hydratase; N-terminus of this ORF was identified by Edman sequencing; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa) |
| | acsA | acetyl-CoA synthetase. (562 aa) |
| | ST0057 | Hypothetical protein; N-term changed (-9). (306 aa) |
| | ST0062 | medium-chain-fatty-acid--CoA ligase. (510 aa) |
| | ST0063 | Putative 4-hydroxybutyryl-CoA dehydratase; N-term changed (-15). (465 aa) |
| | ST0066 | Putative acyl-CoA dehydrogenase. (389 aa) |
| | ST0068 | Hypothetical protein. (165 aa) |
| | ST0069 | Protein synonym:3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (652 aa) |
| | ST0076 | Putative acyl-CoA dehydrogenase. (400 aa) |
| | aas | Putative acyl-acyl carrier protein synthetase. (536 aa) |
| | ST0079 | Putative acyl-CoA acyltransferase. (397 aa) |
| | ST0081 | Putative formate dehydrogenase. (973 aa) |
| | ST0085 | Hypothetical protein. (266 aa) |
| | ST0086 | (R)-specific enoyl-CoA hydratase. (144 aa) |
| | ST0087 | Putative acyl-CoA dehydrogenase. (360 aa) |
| | ST0095 | enoyl-CoA hydratase. (243 aa) |
| | ST0096 | Putative acyl-CoA acyltransferase. (373 aa) |
| | ST0098 | Glutamate dehydrogenase; Fragment. (168 aa) |
| | ST0100 | Glutamate dehydrogenase; N-term changed (-48); fragment. (121 aa) |
| | ST0114 | Malate dehydrogenase; Protein synonym:NADP(+)-dependent malic enzyme. (414 aa) |
| | ST0156 | Putative glutamine synthetase; N-term changed (-138); protein synonym:glutamate--ammonia ligase; Belongs to the glutamine synthetase family. (437 aa) |
| | alaX | Misacylated tRNA(Ala) hydrolase AlaX. (207 aa) |
| | trpS | tryptophanyl-tRNA synthetase; N-term changed (-75); protein synonym:tryptophan--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (381 aa) |
| | lysK | Acetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. (346 aa) |
| | argD/lysJ | Acetylornithine/acetyl-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (387 aa) |
| | lysX | Lysine biosynthesis protein LysX; Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma- carboxyl group of the C-terminal glutamate residue in LysW. (285 aa) |
| | lysW | Alpha-aminoadipate carrier protein LysW; Carrier protein that bears the covalently bound substrates for arginine and lysine biosynthesis; bound L-glutamate is sequentially converted to L-ornithine, while bound alpha-aminoadipate (AAA) is sequentially converted to L-lysine. (56 aa) |
| | lysM | Transcriptional regulator LysM; In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha-aminoadipate (AAA) pathway. (140 aa) |
| | argB/lysZ | Acetylglutamate/acetylaminoadipate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (261 aa) |
| | argC/lysY | N-acetyl-gamma-glutamyl-phosphate/N-acetyl- gamma-aminoadipyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (349 aa) |
| | ST0202 | Hypothetical protein; N-term changed (-123). (541 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (429 aa) |
| | hemD | Putative uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (211 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (531 aa) |
| | dfp | Coenzyme A biosynthesis bifunctional protein CoaBC; Protein synonym:DNA/pantothenate metabolism flavoprotein; protein synonym:phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase. (412 aa) |
| | ST0278 | Malate dehydrogenase; N-term changed (-51); protein synonym:NADP(+)-dependent malic enzyme. (426 aa) |
| | ST0284 | Hypothetical protein. (195 aa) |
| | ST0294 | Prephenate dehydrogenase. (202 aa) |
| | tdcB | Threonine dehydratase. (404 aa) |
| | ST0303 | Hydrolase. (307 aa) |
| | hisS | histidyl-tRNA synthetase; Protein synonym:histidine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (426 aa) |
| | ST0348 | Putative formate dehydrogenase. (654 aa) |
| | glyS | glycyl-tRNA synthetase; Protein synonym:glycine--tRNA ligase. (571 aa) |
| | apgM | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (413 aa) |
| | metE | Methylcobalamin--homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown (By similarity). (338 aa) |
| | ST0386 | Hypothetical protein. (322 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (437 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1047 aa) |
| | leuB | Putative 3-isopropylmalate dehydrogenase/homoisocitrate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (337 aa) |
| | ST0436 | Putative hydrolase. (241 aa) |
| | mtaP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (270 aa) |
| | ST0488 | Putative alpha-L-glutamate ligase. (301 aa) |
| | ST0489 | Putative Lrp family transcriptional regulator. (151 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (306 aa) |
| | ST0506 | Cystathionine lyase; N-term changed (-9). (374 aa) |
| | ST0514 | Protein synonym:acetoacetyl-CoA beta-ketothiolase. (397 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (267 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Carries out the first step of the leucine biosynthesis pathway. (386 aa) |
| | ST2410 | Hypothetical protein. (531 aa) |
| | ST2391 | Putative arsenite oxidase large subunit. (1133 aa) |
| | fba | Fructose-1,6-bisphosphate aldolase; N-terminus of this ORF was identified by Edman sequencing. (272 aa) |
| | cbiP | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (458 aa) |
| | ST2334 | Putative alanine dehydrogenase. (311 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (291 aa) |
| | ST2326 | Hypothetical protein. (239 aa) |
| | queC2 | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)); Belongs to the QueC family. (460 aa) |
| | ST2300 | 2-oxoacid--ferredoxin oxidoreductase alpha subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives. (627 aa) |
| | ST2298 | 2-oxoacid--ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives. (305 aa) |
| | glcD | Putative glycolate oxidase subunit GlcD. (458 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (216 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (408 aa) |
| | aroK | Shikimate kinase. (260 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (390 aa) |
| | aroE | Shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. (260 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (352 aa) |
| | aroG | Phospho-2-dehydro-3-deoxyheptonate aldolase. (330 aa) |
| | tyrA | Putative chorismate mutase/prephenate dehydrogenase. (341 aa) |
| | ST2269 | Putative transketolase; Fragment. (313 aa) |
| | ST2268 | Putative transketolase; Fragment. (273 aa) |
| | ST2256 | Putative acyl-CoA dehydrogenase. (379 aa) |
| | ST2251 | Putative hydrolase; N-term changed (-12). (309 aa) |
| | cysS | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. (468 aa) |
| | gdh-2 | NADP-dependent glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (422 aa) |
| | cimA | Putative (R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (522 aa) |
| | ST2199 | Putative glutamate synthase; Fragment. (656 aa) |
| | ST2198 | Putative glutamate synthase; N-term changed (+231); fragment. (712 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (589 aa) |
| | ST2179 | Mu-crystallin family protein; N-term changed (-129). (305 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (560 aa) |
| | mcr/scr | malonyl-CoA/succinyl-CoA reductase; Catalyzes the reduction of malonyl-CoA to malonate semialdehyde, a key step in the 3-hydroxypropanoate and the 3- hydroxypropanoate/4-hydroxybutyrate cycles. Can also use succinyl-CoA and succinate semialdehyde as substrates but at a lower rate than malonyl-CoA. (359 aa) |
| | idh | Isocitrate dehydrogenase. (409 aa) |
| | ST2145 | Putative hydrolase. (219 aa) |
| | sufS | Putative cysteine desulfurase. (371 aa) |
| | ST2139 | Putative acetyl-CoA synthetase; N-term changed (-33). (565 aa) |
| | dtdA | D-Tyr-tRNA(Tyr) deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (237 aa) |
| | ST2120 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; N-term changed (-84). (203 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (511 aa) |
| | ST2096 | methylmalonyl-CoA mutase small subunit. (140 aa) |
| | ST2095 | Putative acyl-CoA synthetase. (474 aa) |
| | ST2094 | 3-hydroxyacyl-CoA dehydrogenase; N-term changed (+3). (391 aa) |
| | lysS | lysyl-tRNA synthetase; N-term changed (+159); protein synonym:lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (497 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (364 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (229 aa) |
| | fumC | Fumarate hydratase; N-term changed (-3); protein synonym:fumarase C. (438 aa) |
| | ST2022 | Putative hydrolase. (199 aa) |
| | ST2019 | acyl-CoA synthetase. (661 aa) |
| | gcvH-3 | Putative glycine cleavage system H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (148 aa) |
| | gcvH-2 | Putative glycine cleavage system H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (136 aa) |
| | ST1848 | Hypothetical protein. (230 aa) |
| | ST1846 | Regucalcin homolog. (271 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (308 aa) |
| | prpD | Putative 2-methylcitrate dehydratase. (431 aa) |
| | prpB | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (280 aa) |
| | ST1803 | Putative acetyl-CoA synthetase. (621 aa) |
