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| | vapC13 | Putative toxin; N-term changed (+84). (133 aa) |
| | cas6-3 | Putative CRISPR-associated protein Cas6; N-term changed (-48). (269 aa) |
| | ST2640 | CRISPR-associated endonuclease. (227 aa) |
| | cas4-4 | Putative CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (176 aa) |
| | cas2-2 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (91 aa) |
| | cas1-2 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (304 aa) |
| | csa1-2 | Putative CRISPR-associated protein Csa1. (279 aa) |
| | cas4-3 | Putative CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (231 aa) |
| | ST2491 | Hypothetical protein; N-term changed (+75). (272 aa) |
| | cas4-2 | Putative CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (203 aa) |
| | ST2327 | Putative hydrolase. (232 aa) |
| | nucS | Hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (252 aa) |
| | vapC1 | Putative toxin. (96 aa) |
| | ST0008 | Putative CRISPR-associated protein. (242 aa) |
| | ST0009 | Putative CRISPR-associated protein. (279 aa) |
| | ST0013 | Hypothetical protein. (203 aa) |
| | ST0015 | Hypothetical protein. (231 aa) |
| | ST2265 | Hypothetical protein. (340 aa) |
| | cas4 | Putative CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (184 aa) |
| | cas2 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (94 aa) |
| | cas1 | Putative CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (298 aa) |
| | csa1 | Putative CRISPR-associated protein Csa1. (288 aa) |
| | cas6 | Putative CRISPR-associated protein Cas6. (255 aa) |
| | vapC3 | Putative toxin. (128 aa) |
| | ST0161 | Hypothetical protein. (102 aa) |
| | fen-1 | Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (351 aa) |
| | ST0222 | Hypothetical protein. (328 aa) |
| | STK_02508 | Hypothetical protein. (95 aa) |
| | ST0271 | Hypothetical protein. (159 aa) |
| | STK_03225 | RNA splicing endonuclease beta subunit; Protein synonym:RNA intron endonuclease. (92 aa) |
| | ST0336 | Hypothetical protein. (153 aa) |
| | ST0343 | Putative ribonuclease J; Protein synonym:Rnase J. (637 aa) |
| | endA | RNA splicing endonuclease alpha subunit; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (180 aa) |
| | ST0380 | PIN domain protein; N-term changed (-15). (138 aa) |
| | rpp29 | Ribonuclease P protein Rpp29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (77 aa) |
| | xpf | Repair endonuclease XPF. (232 aa) |
| | rrp41 | Exosome core subunit Rrp41; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (243 aa) |
| | pop5 | Ribonuclease P protein Pop5; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (123 aa) |
| | rpp30 | Putative ribonuclease P protein Rpp30; N-term changed (+90). (181 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (208 aa) |
| | ST0579 | RadA paralog; Protein synonym:RecA/Rad51 homologue. (258 aa) |
| | nfi | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (196 aa) |
| | ST2228 | Hypothetical protein. (105 aa) |
| | ST0583 | Hypothetical protein. (324 aa) |
| | ST0604 | Hypothetical protein. (147 aa) |
| | STK_06395 | DNA-binding protein 7d; Can constrain negative DNA supercoils. May be involved in maintaining the integrity of the genome at high temperature. Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family. (64 aa) |
| | STK_06884 | PIN domain protein; N-term changed (+180). (123 aa) |
| | vapC4 | Putative toxin. (124 aa) |
| | rnhA | Ribonuclease HI; Nuclease that specifically degrades the RNA of RNA-DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. In the presence of Mn(2+) or Co(2+) can also cleave an RNA-RNA hybrid; the dsRNase activity is 10- 100-fold lower than RNase H activity. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant. (149 aa) |
| | ST0782 | PIN domain protein. (131 aa) |
| | ST0786 | Hypothetical protein. (138 aa) |
| | fau-1 | RNA-binding protein; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. (412 aa) |
| | vapC5 | Putative toxin. (133 aa) |
| | STK_08685 | Hypothetical protein. (101 aa) |
| | vapC6 | Putative toxin. (125 aa) |
| | vapC7 | Putative toxin; N-term changed (+33). (126 aa) |
| | ST0937 | Putative hydrolase; N-term changed (-36). (227 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (293 aa) |
| | ST0981 | Hypothetical protein. (122 aa) |
| | STK_10324 | Hypothetical protein. (51 aa) |
| | vapC8 | Putative toxin; N-term changed (+78). (133 aa) |
| | ST1125 | PIN domain protein. (125 aa) |
| | ST1151 | Putative ATPase. (551 aa) |
| | ST1153 | Putative ATPase. (683 aa) |
| | STK_11804 | Hypothetical protein. (119 aa) |
| | STK_11807 | Hypothetical protein. (191 aa) |
| | ST1243 | Hypothetical protein. (220 aa) |
| | ST1277 | Hypothetical protein. (249 aa) |
| | STK_13014 | Hypothetical protein; N-term changed (+48). (68 aa) |
| | nth | DNA glycosylase/AP lyase; Protein synonym:endonuclease III homolog. (224 aa) |
| | rpl7ae | 50S ribosomal protein L7Ae/sRNP component; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (126 aa) |
| | polB1 | Protein synonym:DNA polymerase B1. (876 aa) |
| | hjc | Holliday junction resolving enzyme; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products. Inhibits the helicase activity of Hel308 (Hjm). (144 aa) |
| | vapC10 | Putative toxin; N-term changed (-51). (138 aa) |
| | ST1639 | PIN domain protein; N-term changed (+87). (138 aa) |
| | ST1642 | PIN domain protein. (134 aa) |
| | ST1687 | Hypothetical protein. (144 aa) |
| | ST1738 | Hypothetical protein. (379 aa) |
| | cas6-2 | Putative CRISPR-associated protein Cas6; N-term changed (+48). (261 aa) |
| | vapC11 | Putative toxin. (130 aa) |
| | ST1814 | Hypothetical protein. (428 aa) |
| | ST1849 | Hypothetical protein. (103 aa) |
| | ST1910 | Endonuclease; Protein synonym:endodeoxyribonuclease. (241 aa) |
| | ST1932 | Hypothetical protein. (185 aa) |
| | ST1943 | Putative ribonuclease; N-term changed (-9); protein synonym:VapC family protein. (130 aa) |
| | ST1946 | Hypothetical protein. (465 aa) |
| | ST1992 | Hypothetical protein; N-term changed (+168). (337 aa) |
| | vapC12 | Putative toxin; N-term changed (+60). (137 aa) |
| | ST2051 | Hypothetical protein. (242 aa) |
| | pelA | Archaeal Pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (341 aa) |
| | STK_20854 | Hypothetical protein; N-term changed (+96). (89 aa) |
| | STK_20955 | DNA-binding protein 7d. (64 aa) |
| | mre11 | DNA double-strand break repair protein Mre11; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (387 aa) |
| | nurA | 5'-3' nuclease NurA; Involved in DNA double-strand break (DSB) repair (By similarity). Acts probably with HerA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (By similarity). Exhibits both single-stranded endonuclease activity and 5'-3' exonuclease activity on single-stranded and double- stranded DNA. (331 aa) |
| | rpp21 | Ribonuclease P protein Rpp21; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (108 aa) |
| | ST2137 | Hypothetical protein. (162 aa) |
| | ST2148 | AP endonuclease; N-term changed (-42); protein synonym:AP lyase. (275 aa) |
| | ST2188 | Protein synonym:Rnase J. (422 aa) |
