STRINGSTRING
ST0002 ST0002 ST0003 ST0003 cas4 cas4 cas2 cas2 cas1 cas1 STK_00610 STK_00610 ST0071 ST0071 ST0147 ST0147 ST0151 ST0151 alaX alaX ST0174 ST0174 lysK lysK pth pth fen-1 fen-1 dut dut ST0303 ST0303 fbp fbp STK_03225 STK_03225 psmB psmB ahcY ahcY speB speB ntpA ntpA rgy rgy gch3 gch3 ST0401 ST0401 amzA amzA rpp29 rpp29 ST0436 ST0436 xpf xpf rrp41 rrp41 psmA psmA pop5 pop5 rpp30 rpp30 ST0467 ST0467 psmB-2 psmB-2 rnhB rnhB ppa ppa ST0547 ST0547 ST0580 ST0580 nfi nfi ST0582 ST0582 hjm hjm ape2 ape2 ST0669 ST0669 rnhA rnhA ST0773 ST0773 ST0803 ST0803 ST0814 ST0814 ST0815 ST0815 ST0817 ST0817 fau-1 fau-1 htpX1 htpX1 ST0867 ST0867 ST0868 ST0868 pfpI pfpI triN triN ST0926 ST0926 ST0927 ST0927 treX treX ST0937 ST0937 rnz rnz ligT ligT ST0964 ST0964 ST0973 ST0973 ST1008 ST1008 ST1011 ST1011 ST1014 ST1014 pydC pydC ST1020 ST1020 ureC ureC ureAB ureAB arcA arcA ST1094 ST1094 amyA amyA ST1107 ST1107 pydB pydB pydC-2 pydC-2 ST1124 ST1124 triC triC ogg ogg acyP acyP rgy-2 rgy-2 ST1291 ST1291 xpd xpd pepQ pepQ folE folE nth nth ST1404 ST1404 ST1414 ST1414 STK_14180 STK_14180 map map ST1422 ST1422 atpI atpI atpF atpF atpP atpP pdxT pdxT hjc hjc hisE hisE hisH hisH hisI hisI pyrC pyrC purQ purQ argE-2 argE-2 ppx ppx ST1546 ST1546 ST1547 ST1547 ST1548 ST1548 bax1 bax1 ST1632 ST1632 ST1650 ST1650 hyuB hyuB hyuA hyuA copA copA ST1745 ST1745 ape1 ape1 STK_17900 STK_17900 uppP uppP ST1827 ST1827 ST1884 ST1884 ST1910 ST1910 ST1944 ST1944 ST2017 ST2017 ST2022 ST2022 ST2024 ST2024 pelA pelA ST2099 ST2099 herA herA mre11 mre11 rad50 rad50 nurA nurA ST2115 ST2115 dtdA dtdA STK_21250 STK_21250 rpp21 rpp21 ST2145 ST2145 STK_21470 STK_21470 ST2148 ST2148 nudF nudF STK_21570 STK_21570 ST2160 ST2160 thrS2 thrS2 sepP sepP STK_22380 STK_22380 nudF-2 nudF-2 ST2251 ST2251 xpd-2 xpd-2 nucS nucS ST2305 ST2305 ST2317 ST2317 pepQ-2 pepQ-2 ST2324 ST2324 ST2327 ST2327 cas4-2 cas4-2 ST2340 ST2340 htpX2 htpX2 ST2353 ST2353 ST2367 ST2367 ST2402 ST2402 codA codA ST2405 ST2405 ST2441 ST2441 ST2459 ST2459 cas4-3 cas4-3 ST2508 ST2508 ST2511 ST2511 malA malA ST2526 ST2526 ST2529 ST2529 nagA nagA argE-3 argE-3 galS galS ST2570 ST2570 ST2609 ST2609 ST2620 ST2620 cas1-2 cas1-2 cas2-2 cas2-2 cas4-4 cas4-4 ST2640 ST2640
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ST0002Prolyl endopeptidase. (579 aa)
ST0003Putative ATP-dependent helicase. (949 aa)
cas4Putative CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (184 aa)
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (94 aa)
cas1Putative CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (298 aa)
STK_00610Hypothetical protein; Belongs to the thioesterase PaaI family. (138 aa)
ST0071Carboxylesterase. (303 aa)
ST0147Putative ATP-dependent helicase. (621 aa)
ST0151L-amidase. (318 aa)
alaXMisacylated tRNA(Ala) hydrolase AlaX. (207 aa)
ST0174Fe-S cluster carrier protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (298 aa)
lysKAcetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. (346 aa)
pthpeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (121 aa)
fen-1Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (351 aa)
dutdUTP diphosphatase; Catalyzes the deamination of dCTP to dUTP. (183 aa)
ST0303Hydrolase. (307 aa)
fbpFructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (384 aa)
STK_03225RNA splicing endonuclease beta subunit; Protein synonym:RNA intron endonuclease. (92 aa)
psmBProteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (197 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (415 aa)
speBAgmatinase; Belongs to the arginase family. (295 aa)
ntpANucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (189 aa)
rgyReverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1233 aa)
gch3GTP cyclohydrolase III; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family. (225 aa)
ST0401Putative ATP-dependent DNA helicase. (911 aa)
amzAArchaemetzincin; Probable zinc metalloprotease whose natural substrate is unknown. (177 aa)
rpp29Ribonuclease P protein Rpp29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (77 aa)
ST0436Putative hydrolase. (241 aa)
xpfRepair endonuclease XPF. (232 aa)
rrp41Exosome core subunit Rrp41; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (243 aa)
psmAProteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (235 aa)
pop5Ribonuclease P protein Pop5; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (123 aa)
rpp30Putative ribonuclease P protein Rpp30; N-term changed (+90). (181 aa)
ST0467Mini-chromosome maintenance protein; N-term changed (+414); protein synonym:MCM; protein synonym:replicative DNA helicase; Belongs to the MCM family. (686 aa)
psmB-2Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (207 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (208 aa)
ppaInorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions; Belongs to the PPase family. (172 aa)
ST0547Putative inositol monophosphatase. (264 aa)
ST0580Protein-tyrosine phosphatase; N-term changed (-3). (156 aa)
nfiEndonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (196 aa)
ST0582Isochorismatase hydrolase family protein. (200 aa)
hjmHolliday junction migration helicase; An ATP, Mg(2+)-dependent DNA 3'-5' and 5'-3' helicase that may be involved in repair of stalled replication forks. Stimulated by both ss and dsDNA. Unwinds both leading and lagging strands in replication fork structures, unlike orthologs in P. furiosus and M. thermautotrophicus which only unwind the lagging strand and only have 3'-5' helicase activity. Preferentially binds dsDNA with overhangs or branched DNA. Able to anneal DNA substrates that could form a replication fork-like structure, has replication fork reversal activity (at least in vitro); [...] (704 aa)
ape2Probable leucyl aminopeptidase; Belongs to the peptidase M1 family. (781 aa)
ST0669Glycerophosphoryl diester phosphodiesterase. (226 aa)
rnhARibonuclease HI; Nuclease that specifically degrades the RNA of RNA-DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. In the presence of Mn(2+) or Co(2+) can also cleave an RNA-RNA hybrid; the dsRNase activity is 10- 100-fold lower than RNase H activity. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant. (149 aa)
ST0773Beta-glycosidase; Belongs to the glycosyl hydrolase 1 family. (384 aa)
ST0803Pyrimidine-specific ribonucleoside hydrolase. (308 aa)
ST0814Putative glycosidase. (608 aa)
ST0815Glucan 1,4-alpha-glucosidase; Protein synonym:glucoamylase. (615 aa)
ST0817Putative glycosidase. (443 aa)
fau-1RNA-binding protein; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. (412 aa)
htpX1Protease HtpX homolog; Belongs to the peptidase M48B family. (311 aa)
ST0867Putative diacetylchitobiose deacetylase. (221 aa)
ST0868Putative glycosidase. (683 aa)
pfpIIntracellular protease PfpI; N-terminus of this ORF was identified by Edman sequencing. (173 aa)
triNTricorn protease homolog; Degrades oligopeptides in a sequential manner; Belongs to the peptidase S41B family. (195 aa)
ST0926Maltooligosyltrehalose trehalohydrolase; Fragment. (217 aa)
ST0927Maltooligosyltrehalose trehalohydrolase; Fragment. (359 aa)
treXGlycogen debranching enzyme TreX. (716 aa)
ST0937Putative hydrolase; N-term changed (-36). (227 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (293 aa)
ligT2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (195 aa)
ST0964Protein synonym:AP lyase. (240 aa)
ST0973Putative glycosidase; N-term changed (-51). (589 aa)
ST1008Alpha-mannosidase. (951 aa)
ST1011Putative dihydropyrimidinase; Protein synonym:hydantoinase. (433 aa)
ST1014Putative cytosine deaminase. (355 aa)
pydCBeta-alanine synthase; Protein synonym:beta-ureidopropionase. (264 aa)
ST1020Putative dihydropyrimidinase; Protein synonym:hydantoinase. (413 aa)
ureCUrease alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (493 aa)
ureABUrease gamma/beta subunit; N-term changed (-15); In the N-terminal section; belongs to the urease gamma subunit family. (219 aa)
arcAArginine deiminase. (378 aa)
ST1094Putative DNA glycosylase. (282 aa)
amyAAlpha-amylase; N-term changed (+12). (899 aa)
ST1107Putative glycosidase; N-term changed (-42). (621 aa)
pydBDihydropyrimidinase; Protein synonym:hydantoinase. (464 aa)
pydC-2Beta-alanine synthase; N-term changed (-9); N-terminus of this ORF was identified by Edman sequencing; protein synonym:beta-ureidopropionase. (278 aa)
ST1124Putative glycosidase. (571 aa)
triCTricorn protease homolog; Degrades oligopeptides in a sequential manner; Belongs to the peptidase S41B family. (854 aa)
oggProbable 8-oxoguanine DNA glycosylase/DNA lyase; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites); Belongs to the type-2 OGG1 family. (204 aa)
acyPAcylphosphatase. (90 aa)
rgy-2Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1156 aa)
ST1291Putative ATP-dependent DNA helicase. (929 aa)
xpdDNA repair helicase XPD. (540 aa)
pepQProline dipeptidase; Protein synonym:prolidase; Belongs to the peptidase M24B family. (359 aa)
folEGTP cyclohydrolase I; N-term changed (-24). (207 aa)
nthDNA glycosylase/AP lyase; Protein synonym:endonuclease III homolog. (224 aa)
ST1404ATP-dependent DNA helicase. (873 aa)
ST1414Putative hydrolase. (255 aa)
STK_14180Hypothetical protein; N-terminus of this ORF was identified by Edman sequencing; Belongs to the UPF0173 family. (227 aa)
mapMethionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (297 aa)
ST1422Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (228 aa)
atpIPutative membrane-associated ATPase a subunit; Protein synonym:ATP synthase; Belongs to the V-ATPase 116 kDa subunit family. (701 aa)
atpFPutative membrane-associated ATPase F subunit; Protein synonym:ATP synthase. (100 aa)
atpPMembrane-associated ATPase proteolipid subunit; The C chain is a proteolipid, and one of the membranous subunits of the nonenzymatic component of the Sul-ATPase complex. (101 aa)
pdxTPyridoxal 5'-phosphate biosynthesis protein PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (200 aa)
hjcHolliday junction resolving enzyme; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products. Inhibits the helicase activity of Hel308 (Hjm). (144 aa)
hisEphosphoribosyl-ATP pyrophosphatase; N-term changed (-42). (94 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (118 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (389 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa)
argE-2Putative acetylornithine deacetylase. (382 aa)
ppxExopolyphosphatase. (417 aa)
ST1546Putative protein-histidine phosphatase; N-terminus of this ORF was identified by Edman sequencing. (159 aa)
ST1547Putative peptidase M48 family protein. (260 aa)
ST1548Putative hydrolase. (194 aa)
bax1Endonuclease Bax1. (481 aa)
ST1632Putative dUTP diphosphatase; N-term changed (-24); protein synonym:dUTPase. (159 aa)
ST1650Carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. (490 aa)
hyuBPutative hydantoinase HyuB. (503 aa)
hyuAHydantoinase HyuA. (641 aa)
copACopper-transporting ATPase. (740 aa)
ST1745Acylpeptide hydrolase; Protein synonym:acylaminoacyl-peptidase. (565 aa)
ape1Probable leucyl aminopeptidase; Belongs to the peptidase M1 family. (786 aa)
STK_17900Hypothetical protein; Belongs to the thioesterase PaaI family. (133 aa)
uppPPutative undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). (264 aa)
ST1827Putative L-asparaginase. (271 aa)
ST1884Putative protein deacetylase. (332 aa)
ST1910Endonuclease; Protein synonym:endodeoxyribonuclease. (241 aa)
ST1944Hypothetical protein. (293 aa)
ST2017Glucan 1,4-alpha-glucosidase; Protein synonym:glucoamylase. (599 aa)
ST2022Putative hydrolase. (199 aa)
ST20248-oxo-dGTPase; Protein synonym:8-oxo-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase. (151 aa)
pelAArchaeal Pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (341 aa)
ST2099Hydrolase; N-terminus of this ORF was identified by Edman sequencing. (193 aa)
herABipolar DNA helicase HerA; Involved in DNA double-strand break (DSB) repair. Acts probably with NurA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (By similarity). Exhibits DNA-dependent ATPase activity and DNA helicase activity. Loads on either a 3' or a 5' DNA tail for subsequent DNA unwinding. Can also unwind blunt-ended dsDNA, Holliday junction and splayed-arm DNA ; Belongs to the HerA family. (495 aa)
mre11DNA double-strand break repair protein Mre11; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (387 aa)
rad50DNA double-strand break repair ATPase Rad50; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (879 aa)
nurA5'-3' nuclease NurA; Involved in DNA double-strand break (DSB) repair (By similarity). Acts probably with HerA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (By similarity). Exhibits both single-stranded endonuclease activity and 5'-3' exonuclease activity on single-stranded and double- stranded DNA. (331 aa)
ST2115Purine-specific ribonucleoside hydrolase. (306 aa)
dtdAD-Tyr-tRNA(Tyr) deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (237 aa)
STK_21250Hypothetical protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (169 aa)
rpp21Ribonuclease P protein Rpp21; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (108 aa)
ST2145Putative hydrolase. (219 aa)
STK_21470Phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (226 aa)
ST2148AP endonuclease; N-term changed (-42); protein synonym:AP lyase. (275 aa)
nudFProtein synonym:ADP-ribose diphosphatase. (175 aa)
STK_21570Hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. (169 aa)
ST2160Hydrolase. (269 aa)
thrS2Misacylated tRNA(Thr) hydrolase; N-term changed (+354); protein synonym:ThrRS-2; protein synonym:threonyl-tRNA synthetase editing domain. (385 aa)
sepPDolicholpyrophosphatase; Protein synonym:membrane-bound acid pyrophosphatase. (203 aa)
STK_22380uracil-DNA glycosylase; Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP; Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. (220 aa)
nudF-2Protein synonym:ADP-ribose diphosphatase. (146 aa)
ST2251Putative hydrolase; N-term changed (-12). (309 aa)
xpd-2DNA repair helicase XPD. (548 aa)
nucSHypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (252 aa)
ST2305Protein deacetylase; N-term changed (-36). (350 aa)
ST2317Putative ATP-dependent helicase; N-term changed (-45). (738 aa)
pepQ-2Proline dipeptidase; Protein synonym:prolidase; Belongs to the peptidase M24B family. (353 aa)
ST2324Putative protein deacetylase. (329 aa)
ST2327Putative hydrolase. (232 aa)
cas4-2Putative CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (203 aa)
ST2340Hypothetical protein. (170 aa)
htpX2Protease HtpX homolog; Belongs to the peptidase M48B family. (325 aa)
ST2353Putative UDP-sulfoquinovose synthase. (386 aa)
ST2367Protein-serine/threonine phosphatase; N-term changed (-24). (289 aa)
ST2402Putative hydrolase. (459 aa)
codACytosine deaminase. (412 aa)
ST2405uracil-DNA glycosylase; N-term changed (+6). (219 aa)
ST2441Putative hydrolase. (338 aa)
ST2459DEAD-box ATP-dependent RNA helicase. (337 aa)
cas4-3Putative CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (231 aa)
ST2508Isochorismatase hydrolase family protein. (186 aa)
ST2511Dienelactone hydrolase; N-term changed (-6); N-terminus of this ORF was identified by Edman sequencing; protein synonym:carboxymethylenebutenolidase. (259 aa)
malAAlpha-glucosidase; Protein synonym:maltase; Belongs to the glycosyl hydrolase 31 family. (641 aa)
ST2526Putative glycosidase. (646 aa)
ST2529Putative glycosidase. (836 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase. (371 aa)
argE-3Putative acetylornithine deacetylase. (374 aa)
galSAlpha-galactosidase; N-term changed (-72). (650 aa)
ST2570L-2-haloacid dehalogenase. (201 aa)
ST2609Putative glycosidase. (661 aa)
ST2620Putative hydrolase. (220 aa)
cas1-2CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (304 aa)
cas2-2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (91 aa)
cas4-4Putative CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (176 aa)
ST2640CRISPR-associated endonuclease. (227 aa)
Your Current Organism:
Sulfurisphaera tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii str. 7, Sulfurisphaera tokodaii str. 7, Sulfurisphaera tokodaii strain 7
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