STRINGSTRING
Lpd Lpd GloA GloA CaiA CaiA PaaJ PaaJ Tdh Tdh AtoD AtoD AtoA AtoA MgsA MgsA Sbm Sbm Sbm2 Sbm2 GloA2 GloA2 ackA ackA Pta Pta Lpd2 Lpd2 Sbm5 Sbm5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LpdDihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes; Best Blastp hit = gi|13622179|gb|AAK33923.1| '(AE006548) putative dihydrolipoamide dehydrogenase, component E3 [Streptococcus pyogenes]', score 313, E-value 4.00E-84. (461 aa)
GloALactoylglutathione lyase and related lyases; Best Blastp hit = gi|10174085|dbj|BAB05187.1| (AP001512) BH1468; unknown conserved protein [Bacillus halodurans], score 61.2, E-value 7.00E-09. (150 aa)
CaiAAcyl-CoA dehydrogenases; Best Blastp hit = gi|11252723|pir||T45286 butyryl-CoA dehydrogenase (EC 1.3.99.2) [imported] - Clostridium thermosaccharolyticum gi|1903328|emb|CAB07496.1| (Z92974) butyryl-CoA dehydrogenase [Thermoanaerobacterium thermosaccharolyticum], score 601, E-value 1.00E-171. (380 aa)
PaaJBest Blastp hit = gi|11257341|pir||T45290 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) [imported] - Clostridium thermosaccharolyticum gi|1667356|emb|CAB04793.1| (Z82038) acetyl coenzyme A acetyltransferase (thiolase) [Thermoanaerobacterium thermosaccharolyticum] gi|1903332|emb|CAB07500.1| (Z92974) acetyl coenzyme A acetyltransferase (thiolase) [Thermoanaerobacterium thermosaccharolyticum], score 561, E-value 1.00E-159; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
TdhThreonine dehydrogenase and related Zn-dependent dehydrogenases; Best Blastp hit = gi|113443|sp|P14941|ADH_THEBR NADP-DEPENDENT ALCOHOL DEHYDROGENASE gi|80623|pir||A32973 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) - Thermoanaerobacter brockii gi|2914637|pdb|1YKF|A 'Chain A, Nadp-Dependent Alcohol Dehydrogenase From Thermoanaerobium Brockii' gi|2914638|pdb|1YKF|B 'Chain B, Nadp-Dependent Alcohol Dehydrogenase From Thermoanaerobium Brockii' gi|2914639|pdb|1YKF|C 'Chain C, Nadp-Dependent Alcohol Dehydrogenase From Thermoanaerobium Brockii' gi|2914640|pdb|1YKF|D 'Chain D, Nadp-Dependent Al [...] (352 aa)
AtoDAcyl-CoA:acetate CoA transferase alpha subunit; Best Blastp hit = gi|5880875|gb|AAD54947.1|AF157306_2 (AF157306) acetoacetate:butyrate/acetate coenzyme A transferase [Clostridium beijerinckii], score 307, E-value 7.00E-83. (221 aa)
AtoAAcyl-CoA:acetate CoA transferase beta subunit; Best Blastp hit = gi|5880876|gb|AAD54948.1|AF157306_3 (AF157306) acetoacetate:butyrate/acetate coenzyme A transferase [Clostridium beijerinckii], score 310, E-value 1.00E-83. (221 aa)
MgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (129 aa)
SbmMethylmalonyl-CoA mutase, N-terminal domain/subunit; Best Blastp hit = gi|7519968|pir||C75130 methylmalonyl-CoA mutase (EC 5.4.99.2) chain A [similarity] - Pyrococcus abyssi (strain Orsay) gi|5458267|emb|CAB49756.1| '(AJ248285) methylmalonyl-CoA mutase, subunit alpha, N-terminus (mcmA1) [Pyrococcus abyssi]', score 780, E-value 0. (559 aa)
Sbm2Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding); Best Blastp hit = gi|6137077|emb|CAB59633.1| '(AJ246005) isobutyryl-CoA mutase, small subunit [Streptomyces cinnamonensis]', score 195, E-value 2.00E-49. (135 aa)
GloA2Lactoylglutathione lyase and related lyases; Best Blastp hit = gi|14010616|gb|AAK52053.1|AF364548_1 (AF364548) methylmalonyl-CoA epimerase [Pyrococcus horikoshii], score 181, E-value 3.00E-45. (133 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)
PtaPhosphotransacetylase; Best Blastp hit = gi|3006123|emb|CAA06174.1| (AJ004870) phosphotransacetylase [Thermoanaerobacterium thermosaccharolyticum], score 444, E-value 1.00E-124. (331 aa)
Lpd2Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes; Best Blastp hit = gi|2147325|pir||I40794 dihydrolipoamide dehydrogenase (EC 1.8.1.4) [validated] - Clostridium magnum gi|472330|gb|AAA21748.1| (L31844) dihydrolipoamide dehydrogenase [Clostridium magnum], score 395, E-value 1.00E-109. (451 aa)
Sbm5Methylmalonyl-CoA mutase, N-terminal domain/subunit; Best Blastp hit = gi|7519968|pir||C75130 methylmalonyl-CoA mutase (EC 5.4.99.2) chain A [similarity] - Pyrococcus abyssi (strain Orsay) gi|5458267|emb|CAB49756.1| '(AJ248285) methylmalonyl-CoA mutase, subunit alpha, N-terminus (mcmA1) [Pyrococcus abyssi]', score 762, E-value 0. (559 aa)
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.