STRINGSTRING
Fba Fba PpsA PpsA fbp fbp GpmB GpmB ackA ackA Pta Pta HybA HybA TTE1708 TTE1708 Eno Eno PfkA PfkA TTE1865 TTE1865 comB comB GlyA GlyA GpmA GpmA SerA2 SerA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FbaFructose/tagatose bisphosphate aldolase; Best Blastp hit = gi|6652729|gb|AAF22441.1|AF052204_1 '(AF052204) fructose-1,6-bisphosphate aldolase [Thermus aquaticus]', score 313, E-value 2.00E-84. (283 aa)
PpsAPhosphoenolpyruvate synthase/pyruvate phosphate dikinase; Best Blastp hit = gi|7521303|pir||E72754 probable phosphoenolpyruvate synthase APE0026 - Aeropyrum pernix (strain K1) gi|5103414|dbj|BAA78935.1| (AP000058) 622aa long hypothetical phosphoenolpyruvate synthase [Aeropyrum pernix], score 68.2, E-value 3.00E-10. (556 aa)
fbpConserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (362 aa)
GpmBBest Blastp hit = gi|7451679|pir||G72260 phosphoglycerate mutase - Thermotoga maritima (strain MSB8) gi|4981935|gb|AAD36444.1|AE001791_6 (AE001791) phosphoglycerate mutase [Thermotoga maritima], score 147, E-value 1.00E-34. (206 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)
PtaPhosphotransacetylase; Best Blastp hit = gi|3006123|emb|CAA06174.1| (AJ004870) phosphotransacetylase [Thermoanaerobacterium thermosaccharolyticum], score 444, E-value 1.00E-124. (331 aa)
HybABest Blastp hit = gi|7432710|pir||A75061 formate dehydrogenase iron-sulfur chain related protein PAB1390 - Pyrococcus abyssi (strain Orsay) gi|5458895|emb|CAB50382.1| (AJ248287) FORMATE DEHYDROGENASE IRON-SULFUR SUBUNIT related protein [Pyrococcus abyssi], score 113, E-value 1.00E-24. (161 aa)
TTE1708Carbon monoxide dehydrogenase subunit CooS; Best Blastp hit = gi|11095246|gb|AAG29809.1|AF249899_2 (AF249899) carbon monoxide dehydrogenase subunit CooS [Carboxydothermus hydrogenoformans], score 864, E-value 0. (642 aa)
EnoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
PfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa)
TTE1865Formylmethanofuran dehydrogenase subunit E; Best Blastp hit = gi|7450957|pir||G69045 conserved hypothetical protein MTH1345 - Methanobacterium thermoautotrophicum (strain Delta H) gi|2622451|gb|AAB85822.1| (AE000897) conserved protein [Methanothermobacter thermautotrophicus], score 150, E-value 1.00E-35. (169 aa)
comBConserved hypothetical protein; Best Blastp hit = gi|7462280|pir||F72334 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981326|gb|AAD35879.1|AE001747_22 (AE001747) conserved hypothetical protein [Thermotoga maritima], score 191, E-value 1.00E-47; Belongs to the ComB family. (241 aa)
GlyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa)
GpmAPhosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa)
SerA2Phosphoglycerate dehydrogenase and related dehydrogenases; Best Blastp hit = gi|3122874|sp|Q58424|SERA_METJA D-3-PHOSPHOGLYCERATE DEHYDROGENASE (PGDH) gi|2129189|pir||A64427 phosphoglycerate dehydrogenase (EC 1.1.1.95) - Methanococcus jannaschii gi|1591676|gb|AAB99020.1| (U67544) phosphoglycerate dehydrogenase (serA) [Methanococcus jannaschii], score 446, E-value 1.00E-124; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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