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| | TtdA | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain protein; Best Blastp hit = gi|7437046|pir||D70453 fumarate hydratase (fumarase) - Aquifex aeolicus gi|2984079|gb|AAC07618.1| (AE000756) fumarate hydratase (fumarase) [Aquifex aeolicus], score 291, E-value 9.00E-78. (280 aa) |
| | FumA | Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain protein; Best Blastp hit = gi|7437056|pir||E70445 'C-terminal fumarate hydratase, class I - Aquifex aeolicus' gi|2984001|gb|AAC07546.1| '(AE000750) C-terminal fumarate hydratase, class I [Aquifex aeolicus]', score 227, E-value 7.00E-59. (183 aa) |
| | Lpd | Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes; Best Blastp hit = gi|13622179|gb|AAK33923.1| '(AE006548) putative dihydrolipoamide dehydrogenase, component E3 [Streptococcus pyogenes]', score 313, E-value 4.00E-84. (461 aa) |
| | NagC | Transcriptional regulator; Best Blastp hit = gi|13476027|ref|NP_107597.1| glucose kinase [Mesorhizobium loti] gi|14026787|dbj|BAB53383.1| (AP003011) glucose kinase [Mesorhizobium loti], score 250, E-value 2.00E-65. (315 aa) |
| | LdcC | Arginine/lysine/ornithine decarboxylases; Best Blastp hit = gi|118334|sp|P21885|DCLY_BACSU LYSINE DECARBOXYLASE (LDC) gi|1075862|pir||A54546 lysine decarboxylase (EC 4.1.1.18) cad - Bacillus subtilis gi|580835|emb|CAA41337.1| (X58433) lysine decarboxylase [Bacillus subtilis] gi|2633834|emb|CAB13336.1| (Z99111) lysine decarboxylase [Bacillus subtilis] gi|3282147|gb|AAC24937.1| (AF012285) lysine decarboxylase [Bacillus subtilis], score 359, E-value 5.00E-98. (472 aa) |
| | Fba | Fructose/tagatose bisphosphate aldolase; Best Blastp hit = gi|6652729|gb|AAF22441.1|AF052204_1 '(AF052204) fructose-1,6-bisphosphate aldolase [Thermus aquaticus]', score 313, E-value 2.00E-84. (283 aa) |
| | RpiB | Ribose 5-phosphate isomerase RpiB; Best Blastp hit = gi|10176391|dbj|BAB07486.1| (AP001519) ribose 5-phosphate epimerase (pentose phosphate) [Bacillus halodurans], score 167, E-value 1.00E-40; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (302 aa) |
| | PpsA | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Best Blastp hit = gi|7521303|pir||E72754 probable phosphoenolpyruvate synthase APE0026 - Aeropyrum pernix (strain K1) gi|5103414|dbj|BAA78935.1| (AP000058) 622aa long hypothetical phosphoenolpyruvate synthase [Aeropyrum pernix], score 68.2, E-value 3.00E-10. (556 aa) |
| | Rpe | Pentose-5-phosphate-3-epimerase; Best Blastp hit = gi|10175122|dbj|BAB06221.1| (AP001515) ribulose-phosphate 3-epimerase [Bacillus halodurans], score 163, E-value 2.00E-39. (214 aa) |
| | AceF | Dihydrolipoamide acyltransferases; Best Blastp hit = gi|10173392|dbj|BAB04497.1| (AP001509) dihydrolipoamide S-acetyltransferase [Bacillus halodurans], score 269, E-value 4.00E-71. (414 aa) |
| | TktA | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (667 aa) |
| | TTE0193 | Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; Best Blastp hit = gi|1142714|gb|AAB04152.1| (U28163) phosphoenolpyruvate:mannose phosphotransferase element IIB [Lactobacillus curvatus], score 105, E-value 3.00E-22. (167 aa) |
| | Gnd | 6-phosphogluconate dehydrogenase, family 1; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (467 aa) |
| | LysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (447 aa) |
| | GlcD | FAD/FMN-containing dehydrogenases; Best Blastp hit = gi|10175351|dbj|BAB06449.1| (AP001516) glycolate oxidase subunit [Bacillus halodurans], score 337, E-value 3.00E-91. (469 aa) |
| | OadB | Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (369 aa) |
| | Gly1 | Threonine aldolase; Best Blastp hit = gi|7462865|pir||C72215 L-allo-threonine aldolase - Thermotoga maritima (strain MSB8) gi|4982322|gb|AAD36809.1|AE001813_1 (AE001813) L-allo-threonine aldolase [Thermotoga maritima], score 402, E-value 1.00E-111. (346 aa) |
| | fbp | Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (362 aa) |
| | SgaT | Conserved hypothetical protein; Best Blastp hit = gi|10172835|dbj|BAB03942.1| (AP001507) BH0223; unknown conserved protein [Bacillus halodurans], score 273, E-value 3.00E-72. (425 aa) |
| | SgaB | Phosphotransferase system component IIB of unknown specificity; Best Blastp hit = gi|13469797|gb|AAK27336.1| (AF286670) unknown [Escherichia coli], score 66.2, E-value 1.00E-10. (103 aa) |
| | GloA | Lactoylglutathione lyase and related lyases; Best Blastp hit = gi|10174085|dbj|BAB05187.1| (AP001512) BH1468; unknown conserved protein [Bacillus halodurans], score 61.2, E-value 7.00E-09. (150 aa) |
| | Icd | Isocitrate dehydrogenases; Best Blastp hit = gi|7431248|pir||H72288 isocitrate dehydrogenase - Thermotoga maritima (strain MSB8) gi|4981696|gb|AAD36224.1|AE001772_3 (AE001772) isocitrate dehydrogenase [Thermotoga maritima], score 536, E-value 1.00E-151; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa) |
| | PorA | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|4972241|emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium pasteurianum], score 1671, E-value 0; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. (1173 aa) |
| | AcnA | Best Blastp hit = gi|7514223|pir||F70453 aconitase - Aquifex aeolicus gi|2984078|gb|AAC07617.1| (AE000756) aconitase [Aquifex aeolicus], score 715, E-value 0. (641 aa) |
| | ArcC | Carbamate kinase; Best Blastp hit = gi|7434526|pir||G71073 probable carbamate kinase (fucoxanthin chlorophyll a/c binding protein) - Pyrococcus horikoshii gi|3257702|dbj|BAA30385.1| (AP000005) 314aa long hypothetical carbamate kinase (fucoxanthin chlorophyll a/c binding protein) [Pyrococcus horikoshii], score 330, E-value 1.00E-89. (313 aa) |
| | CaiA | Acyl-CoA dehydrogenases; Best Blastp hit = gi|11252723|pir||T45286 butyryl-CoA dehydrogenase (EC 1.3.99.2) [imported] - Clostridium thermosaccharolyticum gi|1903328|emb|CAB07496.1| (Z92974) butyryl-CoA dehydrogenase [Thermoanaerobacterium thermosaccharolyticum], score 601, E-value 1.00E-171. (380 aa) |
| | FadB | 3-Hydroxyacyl-CoA dehydrogenase; Best Blastp hit = gi|3287855|sp|P77851|HBD_CLOTS 3-HYDROXYBUTYRYL-COA DEHYDROGENASE (BETA-HYDROXYBUTYRYL-COA DEHYDROGENASE) (BHBD) gi|11251231|pir||T45289 3-hydroxybutyryl coenzyme A dehydrogenase [imported] - Clostridium thermosaccharolyticum gi|1667355|emb|CAB04792.1| (Z82038) 3-hydroxybutyryl coenzyme A dehydrogenase [Thermoanaerobacterium thermosaccharolyticum] gi|1903331|emb|CAB07499.1| (Z92974) 3-hydroxybutyryl coenzyme A dehydrogenase [Thermoanaerobacterium thermosaccharolyticum], score 427, E-value 1.00E-118. (281 aa) |
| | PaaJ | Best Blastp hit = gi|11257341|pir||T45290 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) [imported] - Clostridium thermosaccharolyticum gi|1667356|emb|CAB04793.1| (Z82038) acetyl coenzyme A acetyltransferase (thiolase) [Thermoanaerobacterium thermosaccharolyticum] gi|1903332|emb|CAB07500.1| (Z92974) acetyl coenzyme A acetyltransferase (thiolase) [Thermoanaerobacterium thermosaccharolyticum], score 561, E-value 1.00E-159; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | MaoC | Predicted acyl dehydratase; Best Blastp hit = gi|11348000|pir||E83233 conserved hypothetical protein PA3302 [imported] - Pseudomonas aeruginosa (strain PAO1) gi|7248383|dbj|BAA92740.1| (AB040025) (R)-specific enoyl-CoA hydratase [Pseudomonas aeruginosa] gi|9949430|gb|AAG06690.1|AE004752_6 (AE004752) conserved hypothetical protein [Pseudomonas aeruginosa], score 141, E-value 3.00E-33. (138 aa) |
| | GltD | NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Best Blastp hit = gi|7448199|pir||H72230 'glutamate synthase, beta subunit - Thermotoga maritima (strain MSB8)' gi|4982213|gb|AAD36707.1|AE001806_17 '(AE001806) glutamate synthase, beta subunit [Thermotoga maritima]', score 469, E-value 1.00E-131. (464 aa) |
| | AceF2 | Dihydrolipoamide acyltransferases; Best Blastp hit = gi|10174442|dbj|BAB05543.1| (AP001513) acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [Bacillus halodurans], score 227, E-value 2.00E-58. (399 aa) |
| | GltD2 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Best Blastp hit = gi|7448199|pir||H72230 'glutamate synthase, beta subunit - Thermotoga maritima (strain MSB8)' gi|4982213|gb|AAD36707.1|AE001806_17 '(AE001806) glutamate synthase, beta subunit [Thermotoga maritima]', score 531, E-value 1.00E-150. (466 aa) |
| | EutG | Alcohol dehydrogenase IV; Best Blastp hit = gi|9863860|gb|AAG01186.1|AF178965_1 (AF178965) long-chain primary alcohol dehydrogenase [Thermoanaerobacter ethanolicus], score 567, E-value 1.00E-160. (342 aa) |
| | AtoD | Acyl-CoA:acetate CoA transferase alpha subunit; Best Blastp hit = gi|5880875|gb|AAD54947.1|AF157306_2 (AF157306) acetoacetate:butyrate/acetate coenzyme A transferase [Clostridium beijerinckii], score 307, E-value 7.00E-83. (221 aa) |
| | AtoA | Acyl-CoA:acetate CoA transferase beta subunit; Best Blastp hit = gi|5880876|gb|AAD54948.1|AF157306_3 (AF157306) acetoacetate:butyrate/acetate coenzyme A transferase [Clostridium beijerinckii], score 310, E-value 1.00E-83. (221 aa) |
| | CpsG | Phosphomannomutase; Best Blastp hit = gi|12230879|sp|P26276|ALGC_PSEAE PHOSPHOMANNOMUTASE (PMM) gi|11350779|pir||H82979 phosphomannomutase AlgC PA5322 [imported] - Pseudomonas aeruginosa (strain PAO1) gi|9951640|gb|AAG08707.1|AE004945_1 (AE004945) phosphomannomutase AlgC [Pseudomonas aeruginosa], score 371, E-value 1.00E-102. (455 aa) |
| | NagC2 | Transcriptional regulator; Best Blastp hit = gi|10174042|dbj|BAB05144.1| (AP001512) glucose kinase [Bacillus halodurans], score 169, E-value 5.00E-41. (336 aa) |
| | GlnA | Glutamine synthase; Best Blastp hit = gi|2895904|gb|AAC03061.1| (AF046916) glutamine synthetase type III [Ruminococcus flavefaciens], score 851, E-value 0. (698 aa) |
| | DapD | Tetrahydrodipicolinate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (241 aa) |
| | DapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (251 aa) |
| | DapA | Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa) |
| | Asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (329 aa) |
| | MgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (129 aa) |
| | GlnS | Glutamyl- and glutaminyl-tRNA synthetases; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (481 aa) |
| | PorB | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Best Blastp hit = gi|7431602|pir||C72288 '2-oxoacid ferredoxin oxidoreductase, beta subunit - Thermotoga maritima (strain MSB8)' gi|4981714|gb|AAD36241.1|AE001773_10 '(AE001773) 2-oxoacid ferredoxin oxidoreductase, beta subunit [Thermotoga maritima]', score 316, E-value 2.00E-85. (282 aa) |
| | PorA2 | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|7433691|pir||B72288 '2-oxoacid ferredoxin oxidoreductase, alpha subunit - Thermotoga maritima (strain MSB8)' gi|4981713|gb|AAD36240.1|AE001773_9 '(AE001773) 2-oxoacid ferredoxin oxidoreductase, alpha subunit [Thermotoga maritima]', score 457, E-value 1.00E-127. (559 aa) |
| | PpsA2 | Best Blastp hit = gi|10720401|sp|P22983|PODK_CLOSY 'PYRUVATE,PHOSPHATE DIKINASE (PYRUVATE,ORTHOPHOSPHATE DIKINASE)', score 1194, E-value 0; Belongs to the PEP-utilizing enzyme family. (875 aa) |
| | Zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (485 aa) |
| | PaaK | Coenzyme F390 synthetase; Best Blastp hit = gi|10172807|dbj|BAB03914.1| (AP001507) phenylacetyl-CoA ligase in the phenylacetic acid catabolic pathway [Bacillus halodurans], score 82, E-value 1.00E-14. (445 aa) |
| | CysK | Cysteine synthase; Best Blastp hit = gi|585031|sp|P37887|CYSK_BACSU CYSTEINE SYNTHASE (O-ACETYLSERINE SULFHYDRYLASE) (O-ACETYLSERINE (THIOL)-LYASE) (CSASE) (SUPEROXIDE-INDUCIBLE PROTEIN 11) (SOI11) gi|2126922|pir||S66103 cysteine synthase (EC 4.2.99.8) A - Bacillus subtilis gi|467462|dbj|BAA05308.1| (D26185) cysteine synthetase A [Bacillus subtilis] gi|2632340|emb|CAB11849.1| (Z99104) cysteine synthetase A [Bacillus subtilis], score 356, E-value 2.00E-97; Belongs to the cysteine synthase/cystathionine beta- synthase family. (306 aa) |
| | GdhA | Best Blastp hit = gi|118535|sp|P27346|DHE2_CLODI NAD-SPECIFIC GLUTAMATE DEHYDROGENASE (NAD-GDH) gi|282476|pir||S28829 glutamate dehydrogenase (EC 1.4.1.2) - Clostridium difficile gi|144820|gb|AAA62756.1| (M65250) glutamate dehydrogenase [Clostridium difficile], score 479, E-value 1.00E-134; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (413 aa) |
| | PorA3 | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|3219890|sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) gi|2127893|pir||E64334 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanococcus jannaschii gi|1592279|gb|AAB98264.1| '(U67483) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA) [Methanococcus jannaschii]', score 380, E-value 1.00E-104. (378 aa) |
| | PorB2 | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Best Blastp hit = gi|6685602|sp|Q57957|KORB_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORB (2-KETOGLUTARATE OXIDOREDUCTASE BETA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) gi|2129229|pir||A64367 pyruvate synthase (EC 1.2.7.1) beta chain - Methanococcus jannaschii gi|1591241|gb|AAB98531.1| '(U67503) 2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB) [Methanococcus jannaschii]', score 337, E-value 8.00E-92. (274 aa) |
| | PorG | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; Best Blastp hit = gi|6685601|sp|Q57956|KORC_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORC (2-KETOGLUTARATE OXIDOREDUCTASE GAMMA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE GAMMA SUBUNIT) gi|2127896|pir||H64366 probable 2-oxoglutarate synthase (EC 1.2.7.3) gamma chain - Methanococcus jannaschii gi|1591240|gb|AAB98530.1| '(U67503) 2-ketoglutarate ferredoxin oxidoreductase, subunit gamma (korG) [Methanococcus jannaschii]', score 146, E-value 1.00E-34. (180 aa) |
| | OadB2 | Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (373 aa) |
| | TTE1216 | Ferredoxin 3; Best Blastp hit = gi|7514132|pir||B75168 '2-ketoglutarate ferredoxin oxidoreductase, chain delta PAB0341 - Pyrococcus abyssi (strain Orsay)' gi|5457935|emb|CAB49425.1| '(AJ248284) 2-ketoglutarate ferredoxin oxidoreductase, subunit delta [Pyrococcus abyssi]', score 61.2, E-value 2.00E-09. (67 aa) |
| | Sbm | Methylmalonyl-CoA mutase, N-terminal domain/subunit; Best Blastp hit = gi|7519968|pir||C75130 methylmalonyl-CoA mutase (EC 5.4.99.2) chain A [similarity] - Pyrococcus abyssi (strain Orsay) gi|5458267|emb|CAB49756.1| '(AJ248285) methylmalonyl-CoA mutase, subunit alpha, N-terminus (mcmA1) [Pyrococcus abyssi]', score 780, E-value 0. (559 aa) |
| | Sbm2 | Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding); Best Blastp hit = gi|6137077|emb|CAB59633.1| '(AJ246005) isobutyryl-CoA mutase, small subunit [Streptomyces cinnamonensis]', score 195, E-value 2.00E-49. (135 aa) |
| | GloA2 | Lactoylglutathione lyase and related lyases; Best Blastp hit = gi|14010616|gb|AAK52053.1|AF364548_1 (AF364548) methylmalonyl-CoA epimerase [Pyrococcus horikoshii], score 181, E-value 3.00E-45. (133 aa) |
| | TTE1221 | Hypothetical protein. (89 aa) |
| | AccB | Biotin carboxyl carrier protein; Best Blastp hit = gi|3777506|gb|AAC69172.1| (AF030576) glutaconyl-CoA decarboxylase gamma subunit [Acidaminococcus fermentans], score 98.6, E-value 3.00E-20. (135 aa) |
| | FolD | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (280 aa) |
| | NapF3 | Ferredoxin 2; Best Blastp hit = gi|7431974|pir||F72256 'Fe-hydrogenase, subunit beta - Thermotoga maritima (strain MSB8)' gi|2865516|gb|AAC02685.1| (AF044577) Fe-hydrogenase beta subunit [Thermotoga maritima] gi|4981989|gb|AAD36495.1|AE001794_11 '(AE001794) Fe-hydrogenase, subunit beta [Thermotoga maritima]', score 65.1, E-value 2.00E-10. (72 aa) |
| | PorA4 | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|3219890|sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) gi|2127893|pir||E64334 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanococcus jannaschii gi|1592279|gb|AAB98264.1| '(U67483) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA) [Methanococcus jannaschii]', score 387, E-value 1.00E-106. (378 aa) |
| | PorB3 | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Best Blastp hit = gi|6685602|sp|Q57957|KORB_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORB (2-KETOGLUTARATE OXIDOREDUCTASE BETA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) gi|2129229|pir||A64367 pyruvate synthase (EC 1.2.7.1) beta chain - Methanococcus jannaschii gi|1591241|gb|AAB98531.1| '(U67503) 2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB) [Methanococcus jannaschii]', score 338, E-value 6.00E-92. (274 aa) |
| | PorG2 | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; Best Blastp hit = gi|6685601|sp|Q57956|KORC_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORC (2-KETOGLUTARATE OXIDOREDUCTASE GAMMA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE GAMMA SUBUNIT) gi|2127896|pir||H64366 probable 2-oxoglutarate synthase (EC 1.2.7.3) gamma chain - Methanococcus jannaschii gi|1591240|gb|AAB98530.1| '(U67503) 2-ketoglutarate ferredoxin oxidoreductase, subunit gamma (korG) [Methanococcus jannaschii]', score 150, E-value 1.00E-35. (185 aa) |
| | GdhA2 | Best Blastp hit = gi|118535|sp|P27346|DHE2_CLODI NAD-SPECIFIC GLUTAMATE DEHYDROGENASE (NAD-GDH) gi|282476|pir||S28829 glutamate dehydrogenase (EC 1.4.1.2) - Clostridium difficile gi|144820|gb|AAA62756.1| (M65250) glutamate dehydrogenase [Clostridium difficile], score 519, E-value 1.00E-146; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (416 aa) |
| | GpmB | Best Blastp hit = gi|7451679|pir||G72260 phosphoglycerate mutase - Thermotoga maritima (strain MSB8) gi|4981935|gb|AAD36444.1|AE001791_6 (AE001791) phosphoglycerate mutase [Thermotoga maritima], score 147, E-value 1.00E-34. (206 aa) |
| | LysC | Aspartokinases; Best Blastp hit = gi|10175020|dbj|BAB06119.1| (AP001515) aspartokinase I (alpha and beta subunits) [Bacillus halodurans], score 352, E-value 5.00E-96; Belongs to the aspartokinase family. (398 aa) |
| | TTE1391 | Exopolyphosphatase-related proteins; Best Blastp hit = gi|7445472|pir||F70440 conserved hypothetical protein aq_1630 - Aquifex aeolicus gi|2983973|gb|AAC07520.1| (AE000748) hypothetical protein [Aquifex aeolicus], score 186, E-value 3.00E-46. (317 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa) |
| | Pta | Phosphotransacetylase; Best Blastp hit = gi|3006123|emb|CAA06174.1| (AJ004870) phosphotransacetylase [Thermoanaerobacterium thermosaccharolyticum], score 444, E-value 1.00E-124. (331 aa) |
| | Rpe2 | Pentose-5-phosphate-3-epimerase; Best Blastp hit = gi|10175122|dbj|BAB06221.1| (AP001515) ribulose-phosphate 3-epimerase [Bacillus halodurans], score 270, E-value 1.00E-71; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa) |
| | DapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa) |
| | AraD | Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; Best Blastp hit = gi|9955359|pdb|1DZX|P 'Chain P, L-Fuculose-1-Phosphate Aldolase From Escherichia Coli Mutant R212a' gi|9955360|pdb|1DZY|P 'Chain P, L-Fuculose-1-Phosphate Aldolase From Escherichia Coli Mutant E214a', score 139, E-value 2.00E-32. (215 aa) |
| | NapF4 | Ferredoxin 2; Best Blastp hit = gi|7431974|pir||F72256 'Fe-hydrogenase, subunit beta - Thermotoga maritima (strain MSB8)' gi|2865516|gb|AAC02685.1| (AF044577) Fe-hydrogenase beta subunit [Thermotoga maritima] gi|4981989|gb|AAD36495.1|AE001794_11 '(AE001794) Fe-hydrogenase, subunit beta [Thermotoga maritima]', score 64.7, E-value 2.00E-10. (69 aa) |
| | AceF3 | Dihydrolipoamide acyltransferases; Best Blastp hit = gi|13814762|gb|AAK41752.1| '(AE006767) Dihydrolipoamide S-acetyltransferase, carboxy-end (pdhC) [Sulfolobus solfataricus]', score 187, E-value 1.00E-46. (219 aa) |
| | Lpd2 | Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes; Best Blastp hit = gi|2147325|pir||I40794 dihydrolipoamide dehydrogenase (EC 1.8.1.4) [validated] - Clostridium magnum gi|472330|gb|AAA21748.1| (L31844) dihydrolipoamide dehydrogenase [Clostridium magnum], score 395, E-value 1.00E-109. (451 aa) |
| | HybA | Best Blastp hit = gi|7432710|pir||A75061 formate dehydrogenase iron-sulfur chain related protein PAB1390 - Pyrococcus abyssi (strain Orsay) gi|5458895|emb|CAB50382.1| (AJ248287) FORMATE DEHYDROGENASE IRON-SULFUR SUBUNIT related protein [Pyrococcus abyssi], score 113, E-value 1.00E-24. (161 aa) |
| | TTE1708 | Carbon monoxide dehydrogenase subunit CooS; Best Blastp hit = gi|11095246|gb|AAG29809.1|AF249899_2 (AF249899) carbon monoxide dehydrogenase subunit CooS [Carboxydothermus hydrogenoformans], score 864, E-value 0. (642 aa) |
| | ArgE2 | Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Best Blastp hit = gi|7447174|pir||B69994 Xaa-His dipeptidase homolog ytjP - Bacillus subtilis gi|2293201|gb|AAC00279.1| (AF008220) putative peptidase [Bacillus subtilis] gi|2635482|emb|CAB14976.1| (Z99119) similar to Xaa-His dipeptidase [Bacillus subtilis], score 358, E-value 8.00E-98. (464 aa) |
| | Eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa) |
| | TpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa) |
| | Pgk | 3-phosphoglycerate kinase; Best Blastp hit = gi|129919|sp|P18912|PGK_BACST PHOSPHOGLYCERATE KINASE gi|80216|pir||JQ1399 phosphoglycerate kinase (EC 2.7.2.3) - Bacillus stearothermophilus gi|576239|pdb|1PHP| 3-Phosphoglycerate Kinase (Pgk) (E.C.2.7.2.3) gi|48855|emb|CAA41093.1| (X58059) 3-phosphoglycerate kinase [Bacillus stearothermophilus], score 509, E-value 1.00E-143. (394 aa) |
| | GapA | Best Blastp hit = gi|3915700|sp|P00362|G3P_BACST GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (GAPDH) gi|80204|pir||JS0164 glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Bacillus stearothermophilus gi|142952|gb|AAA22461.1| (M24493) glyceraldehyde-3-phosphate dehydrogenase [Bacillus stearothermophilus], score 490, E-value 1.00E-137. (335 aa) |
| | AcyP | Acylphosphatases; Best Blastp hit = gi|13814066|gb|AAK41170.1| (AE006710) Acylphosphatase [Sulfolobus solfataricus], score 85.5, E-value 1.00E-16. (90 aa) |
| | PckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (521 aa) |
| | OadB3 | Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (375 aa) |
| | Pgi | Glucose-6-phosphate isomerase; Best Blastp hit = gi|120717|sp|P13375|G6PA_BACST GLUCOSE-6-PHOSPHATE ISOMERASE A (GPI A) (PHOSPHOGLUCOSE ISOMERASE A) (PGI-A) gi|68452|pir||NUBSSA glucose-6-phosphate isomerase (EC 5.3.1.9) A [validated] - Bacillus stearothermophilus gi|40046|emb|CAA34634.1| (X16639) phosphoglucose isomerase A (AA 1-449) [Bacillus stearothermophilus], score 617, E-value 1.00E-176. (451 aa) |
| | PykF | Pyruvate kinase; Best Blastp hit = gi|10175785|dbj|BAB06882.1| (AP001517) pyruvate kinase [Bacillus halodurans], score 674, E-value 0; Belongs to the pyruvate kinase family. (583 aa) |
| | PfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa) |
| | TTE1865 | Formylmethanofuran dehydrogenase subunit E; Best Blastp hit = gi|7450957|pir||G69045 conserved hypothetical protein MTH1345 - Methanobacterium thermoautotrophicum (strain Delta H) gi|2622451|gb|AAB85822.1| (AE000897) conserved protein [Methanothermobacter thermautotrophicus], score 150, E-value 1.00E-35. (169 aa) |
| | MipB | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (216 aa) |
| | TTE1919 | Predicted acetamidase/formamidase; Best Blastp hit = gi|10172637|dbj|BAB03744.1| (AP001507) acetamidase [Bacillus halodurans], score 202, E-value 3.00E-51. (299 aa) |
| | Gnd2 | 6-phosphogluconate dehydrogenase, family 1; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (469 aa) |
| | XylB | Sugar (pentulose and hexulose) kinases; Best Blastp hit = gi|12725247|gb|AAK06282.1|AE006447_3 (AE006447) gluconate kinase (EC 2.7.1.12) [Lactococcus lactis subsp. lactis], score 250, E-value 3.00E-65; Belongs to the FGGY kinase family. (494 aa) |
| | LdhA2 | Lactate dehydrogenase and related dehydrogenases; Best Blastp hit = gi|13516509|dbj|BAB40320.1| (AB033995) glyoxylate reductase [Thermococcus litoralis], score 356, E-value 3.00E-97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa) |
| | NagC4 | Transcriptional regulator; Best Blastp hit = gi|7442875|pir||F72246 glucokinase - Thermotoga maritima (strain MSB8) gi|4982035|gb|AAD36537.1|AE001798_2 (AE001798) glucokinase [Thermotoga maritima], score 223, E-value 3.00E-57. (312 aa) |
| | comB | Conserved hypothetical protein; Best Blastp hit = gi|7462280|pir||F72334 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981326|gb|AAD35879.1|AE001747_22 (AE001747) conserved hypothetical protein [Thermotoga maritima], score 191, E-value 1.00E-47; Belongs to the ComB family. (241 aa) |
| | LysA2 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (445 aa) |
| | GlyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa) |
| | ThrA | Homoserine dehydrogenase; Best Blastp hit = gi|6648065|sp|P19582|DHOM_BACSU HOMOSERINE DEHYDROGENASE (HDH) gi|7427665|pir||DEECHS homoserine dehydrogenase (EC 1.1.1.3) - Bacillus subtilis gi|2635723|emb|CAB15216.1| (Z99120) homoserine dehydrogenase [Bacillus subtilis], score 234, E-value 2.00E-60. (426 aa) |
| | PorA6 | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|7433688|pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (strain MSB8) gi|4982338|gb|AAD36824.1|AE001814_6 '(AE001814) 2-oxoisovalerate oxidoreductase, beta subunit, putative [Thermotoga maritima]', score 419, E-value 1.00E-116. (355 aa) |
| | TTE2199 | Ferredoxin 3; Best Blastp hit = gi|7462853|pir||G72214 hypothetical protein TM1758 - Thermotoga maritima (strain MSB8) gi|4982337|gb|AAD36823.1|AE001814_5 '(AE001814) 2-oxoisovalerate oxidoreductase, gamma subunit, putative [Thermotoga maritima]', score 76.6, E-value 4.00E-14. (70 aa) |
| | CysE | Best Blastp hit = gi|541391|pir||E53402 serine O-acetyltransferase (EC 2.3.1.30) cysE [similarity] - Bacillus stearothermophilus, score 293, E-value 1.00E-78. (220 aa) |
| | ArgD | PLP-dependent aminotransferases; Best Blastp hit = gi|12517654|gb|AAG58206.1|AE005536_7 (AE005536) probable ornithine aminotransferase [Escherichia coli O157:H7 EDL933] gi|13363428|dbj|BAB37378.1| (AP002564) probable ornithine aminotransferase [Escherichia coli O157:H7], score 302, E-value 5.00E-81; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (473 aa) |
| | AccB2 | Biotin carboxyl carrier protein; Best Blastp hit = gi|11277203|pir||T44984 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) gamma chain [imported] - Propionigenium modestum gi|2706400|emb|CAA05139.1| '(AJ002015) methylmalonyl-CoA decarboxylase, gamma-subunit [Propionigenium modestum]', score 99, E-value 2.00E-20. (122 aa) |
| | TTE2384 | Hypothetical protein. (85 aa) |
| | Sbm5 | Methylmalonyl-CoA mutase, N-terminal domain/subunit; Best Blastp hit = gi|7519968|pir||C75130 methylmalonyl-CoA mutase (EC 5.4.99.2) chain A [similarity] - Pyrococcus abyssi (strain Orsay) gi|5458267|emb|CAB49756.1| '(AJ248285) methylmalonyl-CoA mutase, subunit alpha, N-terminus (mcmA1) [Pyrococcus abyssi]', score 762, E-value 0. (559 aa) |
| | MIS1 | Formyltetrahydrofolate synthetase; Best Blastp hit = gi|120563|sp|P21164|FTHS_MOOTH FORMATE--TETRAHYDROFOLATE LIGASE (FORMYLTETRAHYDROFOLATE SYNTHETASE) (FHS) (FTHFS) gi|98640|pir||A35942 formate--tetrahydrofolate ligase (EC 6.3.4.3) - Clostridium thermaceticum gi|144816|gb|AAA23240.1| (J02911) formyltetrahydrofolate synthetase (FTHFS) (ttg start codon) (EC 6.3.4.3) [Moorella thermoacetica], score 744, E-value 0. (555 aa) |
| | NagC5 | Transcriptional regulator; Best Blastp hit = gi|10174042|dbj|BAB05144.1| (AP001512) glucose kinase [Bacillus halodurans], score 160, E-value 3.00E-38. (296 aa) |
| | CysK2 | Cysteine synthase; Best Blastp hit = gi|585031|sp|P37887|CYSK_BACSU CYSTEINE SYNTHASE (O-ACETYLSERINE SULFHYDRYLASE) (O-ACETYLSERINE (THIOL)-LYASE) (CSASE) (SUPEROXIDE-INDUCIBLE PROTEIN 11) (SOI11) gi|2126922|pir||S66103 cysteine synthase (EC 4.2.99.8) A - Bacillus subtilis gi|467462|dbj|BAA05308.1| (D26185) cysteine synthetase A [Bacillus subtilis] gi|2632340|emb|CAB11849.1| (Z99104) cysteine synthetase A [Bacillus subtilis], score 362, E-value 5.00E-99; Belongs to the cysteine synthase/cystathionine beta- synthase family. (312 aa) |
| | GpmA | Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa) |
| | ArgD2 | PLP-dependent aminotransferases; Best Blastp hit = gi|9296961|sp|Q9X2A5|ARGD_THEMA ACETYLORNITHINE AMINOTRANSFERASE (ACOAT) gi|7434138|pir||D72211 acetylornithine aminotransferase - Thermotoga maritima (strain MSB8) gi|4982364|gb|AAD36848.1|AE001816_5 (AE001816) acetylornithine aminotransferase [Thermotoga maritima], score 446, E-value 1.00E-124; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (393 aa) |
| | PrsA | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | FruA | Best Blastp hit = gi|131491|sp|P23387|PTFB_RHOCA 'PTS SYSTEM, FRUCTOSE-SPECIFIC IIBC COMPONENT (EIIBC-FRU) (FRUCTOSE-PERMEASE IIBC COMPONENT) (PHOSPHOTRANSFERASE ENZYME II, BC COMPONENT) (EII-FRU)' gi|97494|pir||B37852 'phosphotransferase system enzyme II (EC 2.7.1.69), fructose-specific - Rhodobacter capsulatus' gi|46021|emb|CAA37303.1| (X53150) fructose enzyme II [Rhodobacter capsulatus], score 537, E-value 1.00E-152. (452 aa) |
| | SerA2 | Phosphoglycerate dehydrogenase and related dehydrogenases; Best Blastp hit = gi|3122874|sp|Q58424|SERA_METJA D-3-PHOSPHOGLYCERATE DEHYDROGENASE (PGDH) gi|2129189|pir||A64427 phosphoglycerate dehydrogenase (EC 1.1.1.95) - Methanococcus jannaschii gi|1591676|gb|AAB99020.1| (U67544) phosphoglycerate dehydrogenase (serA) [Methanococcus jannaschii], score 446, E-value 1.00E-124; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa) |
| | TTE2616 | Glycerate kinase; Best Blastp hit = gi|12723784|gb|AAK04954.1|AE006320_3 (AE006320) conserved hypothetical protein [Lactococcus lactis subsp. lactis], score 343, E-value 3.00E-93; Belongs to the glycerate kinase type-1 family. (377 aa) |
| | ThrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (312 aa) |
| | ThrC2 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (351 aa) |
| | ThrA2 | Homoserine dehydrogenase; Best Blastp hit = gi|7431120|pir||F69031 homoserine dehydrogenase (EC 1.1.1.3) - Methanobacterium thermoautotrophicum (strain Delta H) gi|2622343|gb|AAB85721.1| (AE000890) homoserine dehydrogenase [Methanothermobacter thermautotrophicus], score 283, E-value 2.00E-75. (418 aa) |
