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Ta0313 Ta0313 Ta0413 Ta0413 Ta0453 Ta0453 Ta0616 Ta0616 Ta0617 Ta0617 Ta0618 Ta0618 Ta0684 Ta0684 Ta0753 Ta0753 Ta0779 Ta0779 Ta0823 Ta0823 Ta0858 Ta0858 Ta0878 Ta0878 Ta0882 Ta0882 Ta1018 Ta1018 Ta1075 Ta1075 Ta1103 Ta1103 Ta1315 Ta1315 Ta1347 Ta1347 Ta1419 Ta1419 Ta1428 Ta1428
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ta0313Triosephosphate isomerase related protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (216 aa)
Ta0413Conserved hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (404 aa)
Ta0453Glycerate kinase related protein; Similarity to known protein: Methylobacterium extorquens putative glycerate kinase and pyruvate kinase(pykA) genes, complete cds; TREMBLNEW:MEU87316_4. (396 aa)
Ta0616Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (223 aa)
Ta0617Probable transketolase; Strong similarity to known protein: TRANSKETOLASE (EC 2.2.1.1) (TK) (P68) - Mus musculus (Mouse); SWISSPROT:TKT_MOUSE. (316 aa)
Ta0618Probable transketolase; Strong similarity to known protein: TRANSKETOLASE (EC 2.2.1.1) (TK) (P68) - Mus musculus (Mouse); SWISSPROT:TKT_MOUSE. (273 aa)
Ta0684Deoxyribose-phosphate aldolase related protein; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (246 aa)
Ta0753Similarity to known protein: MANNONATE DEHYDRATASE (EC 4.2.1.8) (D-MANNONATE HYDROLASE) - Thermotoga neapolitana; SWISSPROT:UXUA_THENEFunction: Pentose and glucuronate interconversions. (330 aa)
Ta0779Similarity to unknown protein: 2-hydroxyacid dehydrogenase homolog - Archaeoglobus fulgidus; PIR:B69472. Relation: SIM. to PIR:A47117 formate dehydrogenase (EC 1.2.1.2) - Neurospora crassa and to SERA_ARATH phosphoglycerate dehydrogenase (EC 1.1.1.95) - A.taliana, the function is not clear. (309 aa)
Ta0823Weak similarity to known protein. (190 aa)
Ta0858Similarity to known protein: GLYCERATE DEHYDROGENASE (EC 1.1.1.29) (NADH-DEPENDENT HYDROXYPYRUVATEREDUCTASE) (HPR) (GDH) (HYDROXYPYRUVATE DEHYDROGENASE) (GLYOXYLATEREDUCTASE) (HPR-A) - Methylobacterium extorquens; SWISSPROT:DHGY_METEX; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (303 aa)
Ta0878Ribose-5-phosphate isomerase related protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (241 aa)
Ta0882Enolase related protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa)
Ta1018Similarity to known protein: SERINE--GLYOXYLATE AMINOTRANSFERASE (EC 2.6.1.45) (SGAT) - Hyphomicrobium methylovorum; SWISSPROT:SGAA_HYPMEFunction: L-Serine + Glyoxylate = 3-Hydroxypyruvate + Glycine Involved in glycine, serine and threonine metabolism. (382 aa)
Ta1075Probable 3-phosphoglycerate kinase; Strong similarity to known protein: phosphoglycerate kinase (EC 2.7.2.3) [validated] - Methanothermus fervidus (fragment); PIR:PN0008. (408 aa)
Ta1103Strong similarity to known protein: glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Methanothermus fervidus; PIR:JT0286. (338 aa)
Ta1315Probable ribulose-5-phosphate 3-epimerase; Strong similarity to known protein: RIBULOSE-PHOSPHATE 3-EPIMERASE PRECURSOR (EC 5.1.3.1) (PENTOSE-5-PHOSPHATE 3-EPIMERASE) (PPE) (RPE) (R5P3E) - Oryza sativa (Rice); SWISSPROT:RPE_ORYSA. (211 aa)
Ta1347Hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. (214 aa)
Ta1419Conserved hypothetical protein; Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency; Belongs to the PGI/PMI family. (310 aa)
Ta1428Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (375 aa)
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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