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Ta1103 Ta1103 Ta0816 Ta0816 Ta0811 Ta0811 Ta0809 Ta0809 Ta0808 Ta0808 Ta0806 Ta0806 Ta0805 Ta0805 Ta0804 Ta0804 Ta0803 Ta0803 Ta0792 Ta0792 Ta0791 Ta0791 Ta0788 Ta0788 Ta0780 Ta0780 Ta0778 Ta0778 Ta0777 Ta0777 Ta0776 Ta0776 Ta0773 Ta0773 Ta0772 Ta0772 Ta0753 Ta0753 Ta0723 Ta0723 Ta0691 Ta0691 Ta0669 Ta0669 Ta0650 Ta0650 Ta0649 Ta0649 Ta0639 Ta0639 Ta0635 Ta0635 Ta0629 Ta0629 Ta0628 Ta0628 Ta0618 Ta0618 Ta0617 Ta0617 Ta0609 Ta0609 Ta0575 Ta0575 Ta0551 Ta0551 Ta0538 Ta0538 Ta0531 Ta0531 Ta0530 Ta0530 Ta0519 Ta0519 Ta0512 Ta0512 Ta0500 Ta0500 Ta0476 Ta0476 Ta0468 Ta0468 Ta0425 Ta0425 Ta0421 Ta0421 Ta0413 Ta0413 Ta0363 Ta0363 Ta0332 Ta0332 Ta0330 Ta0330 Ta0315 Ta0315 Ta0313 Ta0313 Ta0291 Ta0291 Ta0285 Ta0285 Ta0284 Ta0284 Ta0283 Ta0283 Ta0282 Ta0282 Ta0281 Ta0281 Ta0260 Ta0260 Ta0259 Ta0259 Ta0247 Ta0247 Ta0245 Ta0245 Ta0242 Ta0242 Ta0239 Ta0239 Ta0238 Ta0238 Ta0206 Ta0206 Ta0205 Ta0205 Ta0139 Ta0139 Ta0124 Ta0124 Ta0117 Ta0117 Ta0116 Ta0116 Ta0113 Ta0113 Ta0099 Ta0099 Ta0080 Ta0080 Ta0075 Ta0075 Ta0045 Ta0045 Ta0044 Ta0044 Ta0040 Ta0040 Ta0022 Ta0022 Ta0010 Ta0010 Ta0009 Ta0009 Ta1509 Ta1509 Ta1498 Ta1498 Ta1476 Ta1476 Ta1455 Ta1455 Ta1438 Ta1438 Ta1437 Ta1437 Ta1395 Ta1395 Ta1366 Ta1366 Ta1358 Ta1358 Ta1357 Ta1357 Ta1350 Ta1350 Ta1347 Ta1347 Ta1330 Ta1330 Ta1318 Ta1318 Ta1284 Ta1284 Ta1242 Ta1242 Ta1227 Ta1227 Ta1212 Ta1212 Ta1211 Ta1211 Ta1200 Ta1200 Ta1189 Ta1189 Ta1179 Ta1179 Ta1163 Ta1163 Ta1162 Ta1162 Ta1147 Ta1147 Ta0889 Ta0889 Ta0896 Ta0896 Ta0898 Ta0898 Ta0915 Ta0915 Ta0937 Ta0937 Ta0942 Ta0942 Ta0944 Ta0944 Ta0946 Ta0946 Ta0947 Ta0947 Ta0952 Ta0952 Ta0972 Ta0972 Ta0977 Ta0977 Ta0979 Ta0979 Ta0987 Ta0987 Ta1012 Ta1012 Ta1075 Ta1075 Ta0886 Ta0886 Ta0882 Ta0882 Ta0879 Ta0879 Ta0849 Ta0849 Ta0824 Ta0824
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
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experimentally determined
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gene neighborhood
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Ta1103Strong similarity to known protein: glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Methanothermus fervidus; PIR:JT0286. (338 aa)
Ta0816Similarity to known protein: pyruvate dehydrogenase (cytochrome) (EC 1.2.2.2) - Escherichia coli; PIR:DEECPCFunction: involved in pyruvate metabolism; Belongs to the TPP enzyme family. (548 aa)
Ta0811Similarity to known protein: glycine hydroxymethyltransferase (EC 2.1.2.1) - Methanobacterium thermoautotrophicum (strain Marburg); PIR:S62190Function: involved in glycine, serine and threonine metabolism, also involved in vitamin B6 metabolism. (387 aa)
Ta0809Probable aldehyde dehydrogenase; NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes. (493 aa)
Ta0808Similarity to known protein: indole-3-glycerol-phosphate synthase (EC 4.1.1.48) TrpC - Sulfolobus solfataricus; PIR:C40635; Belongs to the TrpC family. (237 aa)
Ta0806Similarity to known protein: anthranilate synthase (EC 4.1.3.27) component I - Clostridium thermocellum; PIR:JX0065. (356 aa)
Ta0805Weak similarity to known protein. Relation: weak similarity to phosphoribosylanthranilate isomerase - Aquifex aeolicus, PIR:A70478; Belongs to the TrpF family. (179 aa)
Ta0804Anthranilate phosphoribosyltransferase related protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (322 aa)
Ta0803Similarity to known protein: TRYPTOPHAN SYNTHASE ALPHA CHAIN (EC 4.2.1.20).TRYPTOPHAN SYNTHASE ALPHA CHAIN (EC 4.2.1.20) - Sulfolobus solfataricus.Sulfolobus solfataricus; SWISSPROT:TRPA_SULSO. (217 aa)
Ta0792Similarity to known protein: carbamoyl-phosphate synthase, small (or glutamine) subunit (carA) homolog - Archaeoglobus fulgidus; PIR:H69408Function: Urea cycle and metabolism of amino groups, Glutamate metabolism, Arginine and proline metabolism, Nitrogen metabolism; Belongs to the CarA family. (353 aa)
Ta0791Probable carbamoyl-phosphate synthase, large subunit; Strong similarity to known protein: carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus; PIR:I40169. (1047 aa)
Ta0788Diaminopimelate decarboxylase related protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (436 aa)
Ta0780Similarity to known protein: BENZOYLFORMATE DECARBOXYLASE (EC 4.1.1.7) (BFD) (BFDC) - Pseudomonas putida; SWISSPROT:MDLC_PSEPUFunction: Aromatic hydrocarbons catabolism; Mandelate pathway; Belongs to the TPP enzyme family. (497 aa)
Ta0778Similarity to unknown protein: conserved hypothetical protein AF2431 - Archaeoglobus fulgidus; PIR:H69553; Belongs to the PdaD family. (190 aa)
Ta0777Similarity to known protein: leucyl-tRNA synthetase (leuS) homolog - Archaeoglobus fulgidus; PIR:F69552; Belongs to the class-I aminoacyl-tRNA synthetase family. (910 aa)
Ta0776Strong similarity to known protein: GLUTAMATE DEHYDROGENASE (EC 1.4.1.3) (GDH) - Pyrococcus horikoshii; SWISSPROT:DHE3_PYRHO; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa)
Ta0773Strong similarity to known protein: 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain [validated] - Sulfolobus sp. (strain 7); PIR:JC4919. (629 aa)
Ta0772Strong similarity to known protein: 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) beta chain - Sulfolobus sp. (strain 7); PIR:JC4920. (309 aa)
Ta0753Similarity to known protein: MANNONATE DEHYDRATASE (EC 4.2.1.8) (D-MANNONATE HYDROLASE) - Thermotoga neapolitana; SWISSPROT:UXUA_THENEFunction: Pentose and glucuronate interconversions. (330 aa)
Ta0723Similarity to unknown protein: hypothetical protein PAB0997 - Pyrococcus abyssi (strain Orsay); PIR:D75064. (220 aa)
Ta0691Acetolactate synthase, large chain related protein; Similarity to known protein: acetolactate synthase (EC 4.1.3.18) - Caulobacter crescentus; PIR:I40666. Relation: similarity to acetolactate synthase (EC 4.1.3.18) - Caulobacter crescentus; I40666. Function: Valine, leucine and isoleucine biosynthesis, Butanoate metabolism, C5-Branched dibasic acid metabolism, Pantothenate and CoA biosynthesis. (553 aa)
Ta0669Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (424 aa)
Ta0650Strong similarity to known protein: argininosuccinate synthase (EC 6.3.4.5) - Methanococcus vannielii; PIR:AJMXRV; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa)
Ta0649Similarity to known protein: argininosuccinate lyase (EC 4.3.2.1) - goose; PIR:JN0486. (433 aa)
Ta0639Similarity to known protein: phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain, cytosolic [validated] - yeast (Saccharomyces cerevisiae); PIR:YFBYAC; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (499 aa)
Ta0635Strong similarity to known protein: GLUTAMATE DEHYDROGENASE (EC 1.4.1.3) (GDH) - Thermococcus litoralis; SWISSPROT:DHE3_THELIFunction: generally involved with either ammonia assimilation or glutamate catabolism. ORF_prediction: N-terminus longer than those of trelated proteins, however its codon usage does support a coding function of the first 40 aa, the frequency of rare codons is very low, possible second start only after 35 aa, not altered; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (436 aa)
Ta0629Probable 2-ketovalerate ferredoxin oxidoreductase beta-2 chain; Strong similarity to known protein: KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB (EC 1.-.-.-) (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE BETA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) - Pyrococcus furiosus; SWISSNEW:VORB_PYRFUFunction: Pyruvate metabolism, Propanoate metabolism, Butanoate metabolism, Reductive carboxylate cycle (CO2 fixation). (300 aa)
Ta0628Probable 2-ketovalerate ferredoxin oxidoreductase alpha-2 chain; Strong similarity to known protein: KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (EC 1.-.-.-) (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) - Pyrococcus furiosus; SWISSNEW:VORA_PYRFUFunction: Pyruvate metabolism, Propanoate metabolism, Butanoate metabolism, Reductive carboxylate cycle (CO2 fixation). (402 aa)
Ta0618Probable transketolase; Strong similarity to known protein: TRANSKETOLASE (EC 2.2.1.1) (TK) (P68) - Mus musculus (Mouse); SWISSPROT:TKT_MOUSE. (273 aa)
Ta0617Probable transketolase; Strong similarity to known protein: TRANSKETOLASE (EC 2.2.1.1) (TK) (P68) - Mus musculus (Mouse); SWISSPROT:TKT_MOUSE. (316 aa)
Ta0609Similarity to known protein: asparagine--tRNA ligase (EC 6.1.1.22) asnS2 - Lactobacillus delbrueckii subsp. bulgaricus; PIR:S71074. (329 aa)
Ta0575Strong similarity to known protein: probable aspartate carbamoyltransferase catalytic chain - Pyrococcus horikoshii; PIR:A71119. (305 aa)
Ta0551Similarity to known protein: PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN CYTOPLASMIC (EC 6.1.1.20)(PHENYLALANINE--TRNA LIGASE ALPHA CHAIN) (PHERS) - Candida albicans (Yeast); SWISSPROT:SYFA_CANAL. (543 aa)
Ta0538Similarity to unknown protein: probable iron-sulfur protein AF0811 [similarity] - Archaeoglobus fulgidus; PIR:C69351. (373 aa)
Ta0531Probable cystathionine gamma-synthase; Strong similarity to known protein: Arabidopsis thaliana gene for cystathionine gamma-synthase, complete cds; TREMBL:AB010888_1Function: Involved in Cysteine metabolism, Methionine metabolism, Glycine, serine and threonine metabolism, Selenoamino acid metabolism. EC Numbers and enzyme names are mixed up, homologs are called cystathionine gamma-synthase (EC 4.2.99.9) and cystathionine gamma lyase (EC 4.4.1.-). (380 aa)
Ta0530Homoserine kinase related protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (310 aa)
Ta0519Probable asparaginyl--tRNA synthetase; Strong similarity to known protein: asparagine--tRNA ligase (EC 6.1.1.22) asnS2 - Lactobacillus delbrueckii subsp. bulgaricus; PIR:S71074; Belongs to the class-II aminoacyl-tRNA synthetase family. (429 aa)
Ta0512Probable tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (332 aa)
Ta0500Similarity to known protein: BENZOYLFORMATE DECARBOXYLASE (EC 4.1.1.7) (BFD) (BFDC) - Pseudomonas putida; SWISSPROT:MDLC_PSEPUFunction: involved in phenylalanin metabolism; Belongs to the TPP enzyme family. (500 aa)
Ta0476Strong similarity to known protein: Sus scrofa L-3-hydroxyacyl-CoA dehydrogenase precursor (HAD) mRNA, nucleargene encoding mitochondrial protein, complete cds; TREMBL:AF027652_1Function: Fatty acid biosynthesis (path 2), Fatty acid metabolism, Valine, leucine and isoleucine degradation, Lysine degradation, Tryptophan metabolism, Butanoate metabolism. (291 aa)
Ta0468Probable seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (441 aa)
Ta0425Similarity to known protein: formate dehydrogenase (EC 1.2.1.2) H (hydrogenase-linked) - Escherichia coli; PIR1:DEECFS. (996 aa)
Ta0421Probable acetyl-coenzyme-A synthetase; Strong similarity to known protein: acetate--CoA ligase (EC 6.2.1.1) [validated] - Methanothrix soehngenii; PIR:A41043. (647 aa)
Ta0413Conserved hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (404 aa)
Ta0363Similarity to known protein: Ustilgo maydis aspartate semialdehyde dehydrogenase (ASADH) mRNA, completecds; TREMBL:UM44901_1. (338 aa)
Ta0332Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (261 aa)
Ta0330threonine--tRNA ligase related protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (660 aa)
Ta0315Similarity to known protein: Mus musculus asparagine synthetase mRNA, complete cds; TREMBL:MM38940_1. (236 aa)
Ta0313Triosephosphate isomerase related protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (216 aa)
Ta0291Similarity to known protein: Rattus norvegicus L-3-hydroxyacyl-CoA dehydrogenase precursor (HAD) mRNA, complete cds; nuclear gene for mitochondrial product; TREMBL:AF095449_1. (658 aa)
Ta02853-dehyroquinate synthase related protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (360 aa)
Ta0284Shikimate 5-dehydrogenase related protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (268 aa)
Ta0283Conserved hypothetical protein; Similarity to unknown protein: homoserine kinase PAB0301 - Pyrococcus abyssi (strain Orsay); PIR:F75161. (268 aa)
Ta02823-phosphoshikimate 1-carboxyvinyltransferase related protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (410 aa)
Ta0281Similarity to known protein: arginine--tRNA ligase (EC 6.1.1.19) - Corynebacterium glutamicum; PIR1:A49936; Belongs to the class-I aminoacyl-tRNA synthetase family. (546 aa)
Ta0260Probable pyruvate ferredoxin oxidoreductase, beta subunit; Strong similarity to known protein: 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) beta chain - Methanobacterium thermoautotrophicum (strain Delta H); PIR:H69170. (285 aa)
Ta0259Probable pyruvate ferredoxin oxidoreductase, alpha subunit; Strong similarity to known protein: 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain [validated] - Sulfolobus sp. (strain 7); PIR:JC4919. (588 aa)
Ta0247Strong similarity to known protein: Synechocystis sp. ccmA gene for 32.4kD protein and ORF271 for 29.5kDprotein, complete cds; TREMBL:SSCCMA_1. (285 aa)
Ta0245Conserved hypothetical protein; Similarity to unknown protein: chorismate mutase (EC 5.4.99.5) chain A - Methanococcus jannaschii; PIR:G64330. (168 aa)
Ta0242Strong similarity to known protein: HISTIDINE AMMONIA-LYASE (EC 4.3.1.3) (HISTIDASE).HISTIDINE AMMONIA-LYASE (EC 4.3.1.3) (HISTIDASE) - Pseudomonas putida.Pseudomonas putida; SWISSPROT:HUTH_PSEPU; Belongs to the PAL/histidase family. (496 aa)
Ta0239Probable urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (609 aa)
Ta0238Similarity to known protein: ATRAZINE CHLOROHYDROLASE (EC 3.8.1.-) - Pseudomonas sp. (strain ADP); SWISSPROT:ATZA_PSESD; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (410 aa)
Ta0206Similarity to known protein: GLYCYL-TRNA SYNTHETASE (EC 6.1.1.14) (GLYCINE--TRNA LIGASE) (GLYRS) - Arabidopsis thaliana (Mouse-ear cress); SWISSPROT:SYG_ARATH. (476 aa)
Ta0205Strong similarity to known protein: 2, 4-dienoyl-CoA reductase (NADPH) (EC 1.3.1.34) precursor, mitochondrial - human; PIR:S53352. (282 aa)
Ta0139Pyrroline-5-carboxylate reductase related protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (279 aa)
Ta0124alanyl-tRNA synthetase related protein; Similarity to known protein: alanine--tRNA ligase (EC 6.1.1.7) - silkworm; PIR1:SYMTAT. (245 aa)
Ta0117Strong similarity to known protein: isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) - Bacillus subtilis; PIR:I40382. (405 aa)
Ta0116Hypothetical protein; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (228 aa)
Ta0113Strong similarity to known protein: threonine dehydratase (EC 4.2.1.16), biodegradative [validated] - Escherichia coli; PIR:DWECTD. (406 aa)
Ta0099Probable histidyl-tRNA synthetase; Strong similarity to known protein: Arabidopsis thaliana histidyl-tRNA synthetase mRNA, complete cds; TREMBL:AF020715_1; Belongs to the class-II aminoacyl-tRNA synthetase family. (426 aa)
Ta0080Similarity to known protein: cystathionine gamma-lyase (EC 4.4.1.1) - rat; PIR:A49864Function: Methionine metabolism, Selenoamino acid metabolism, Nitrogen metabolism. (384 aa)
Ta0075COBYRIC ACID SYNTHASE related protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity); Belongs to the CobB/CobQ family. CobQ subfamily. (468 aa)
Ta0045Probable formate dehydrogenase, alpha subunit; Strong similarity to known protein: Methanobacterium thermoformicicum formate dehydrogenase operon and flankingregions, formate transporter (fdhC), formate dehydrogenase alpha subunit(fdhA) and formate dehydrogenase beta subunit (fdhB) genes, complete cds; TREMBL:MT52681_3Function: Glyoxylate and dicarboxylate metabolism, Methane metabolism. (702 aa)
Ta0044Probable CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (540 aa)
Ta0040valyl-tRNA synthetase related protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (791 aa)
Ta0022Hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (256 aa)
Ta0010Strong similarity to known protein: aminomethyltransferase (EC 2.1.2.10) [validated] - Escherichia coli; PIR:A56689Function: Glycine, serine and threonine metabolism, One carbon pool by folate, Nitrogen metabolism. (336 aa)
Ta0009Hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (203 aa)
Ta1509Probable glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (436 aa)
Ta1498Probable glutamine synthetase; Strong similarity to known protein: Bacillus subtilis glnR and glnA genes for GlnR protein and glutaminesynthetase, complete cds; TREMBL:BSGLNRA_2. (448 aa)
Ta1476Probable glutamate formiminotransferase; Catalyzes the transfer of the formyl group from N- formylglutamate to tetrahydrofolate (THF) to yield 5- formyltetrahydrofolate (5-CHO-THF) and glutamate (Glu). The triglutamate form of 5-CHO-THF (5-CHO-THF-Glu3) can also be used as substrate. It can also catalyzes the transfer of the formimino group from N-formiminoglutamate to tetrahydrofolate (THF) to yield 5- formiminotetrahydrofolate (5-NH=CH-THF) and glutamate (Glu). It can replace YgfA to catalyzes the irreversible ATP-dependent transformation of 5-CHO-THF to form 5,10-methenyltetrahydrof [...] (303 aa)
Ta1455Conserved hypothetical protein; Strong similarity to unknown protein: acyl carrier protein synthase - Methanococcus jannaschii; PIR:A64493; Belongs to the thiolase-like superfamily. UPF0219 family. (351 aa)
Ta1438Strong similarity to known protein: 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4) alpha chain precursor - human; PIR:DEHUXAORF_prediction: The N-terminus of this protein is short by 60aa compared to other proteins, sequence analysis clearly rules out an elongated N-terminus. (337 aa)
Ta1437Strong similarity to known protein: 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4) chain E1-beta - Pseudomonas putida; PIR:DEPSEB. (319 aa)
Ta1395Similarity to known protein: mandelate racemase (EC 5.1.2.2) - Pseudomonas putida; PIR:A28700. (364 aa)
Ta1366Probable glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (124 aa)
Ta1358Glycine dehydrogenase (decarboxylating) related protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (433 aa)
Ta1357Glycine dehydrogenase (decarboxylating) related protein, subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (472 aa)
Ta1350Probable carbamate kinase; Strong similarity to known protein: CARBAMATE KINASE (EC 2.7.2.2) - Clostridium perfringens; SWISSPROT:ARCC_CLOPEFunction: amino acid fermantation. (339 aa)
Ta1347Hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. (214 aa)
Ta1330Probable ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (297 aa)
Ta1318Phosphoribosylformylglycinamidine synthase I related protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is tho [...] (289 aa)
Ta1284Fragment of probable methionine--tRNA ligase; Strong similarity to known protein: methionine--tRNA ligase (EC 6.1.1.10) - Bacillus stearothermophilus; PIR:S16682. (107 aa)
Ta1242Probable amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (474 aa)
Ta1227Probable carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (294 aa)
Ta1212Translation initiation factor aIF-2B, alpha chain related protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (340 aa)
Ta1211tryptophanyl-tRNA synthetase related protein; Similarity to known protein: H.sapiens mRNA for IFP53; TREMBL:HSIFP53_1; Belongs to the class-I aminoacyl-tRNA synthetase family. (426 aa)
Ta1200Probable cobyrinic acid a, c-diamide synthase (cbiA); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (443 aa)
Ta1189Probable glycine C-acetyltransferase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (393 aa)
Ta1179Similarity to known protein: HOMOSERINE DEHYDROGENASE (EC 1.1.1.3) (HDH) - Bacillus subtilis; SWISSPROT:DHOM_BACSU. (324 aa)
Ta1163Similarity to known protein: LYSYL-TRNA SYNTHETASE (EC 6.1.1.6) (LYSINE--TRNA LIGASE) (LYSRS) - Methanococcus maripaludis; SWISSPROT:SYK_METMP; Belongs to the class-I aminoacyl-tRNA synthetase family. (507 aa)
Ta1162Probable methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. (547 aa)
Ta1147Probable cysteinyl-tRNA synthetase; Strong similarity to known protein: E. coli cysS gene for cysteinyl-tRNA synthetase; TREMBL:ECCYSSG_1. (452 aa)
Ta0889DNA/pantothenate metabolism flavoprotein related protein; Similarity to known protein: Bradyrhizobium japonicum UbiE (ubiE) gene, partial cds; AarF (aarF), panthotenate metabolism flavoprotein (dfp), deoxyuridine-triphosphatase(dut), putative sensor protein (bdfA), GalF-like (galF), hypotheticalprotein genes, complete cds; putative helicase 2 gene, partial cds; andunknown genes; TREMBL:AF042096_2. (394 aa)
Ta0896Similarity to known protein: pyruvate kinase (EC 2.7.1.40) [validated] - Bacillus licheniformis; PIR:JC4220. (544 aa)
Ta0898Methylenetetrahydrofolate dehydrogenase (NADP+) related protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (276 aa)
Ta0915Chorismate mutase/prephenate dehydratase related protein; Similarity to known protein: Pseudomonas stutzeri gyrase A subunit (gyrA) gene, partial cds;3-phosphoserine aminotransferase (serC), chorismate mutase/prephenatedehydratase (aroQp/pheA), imidazole acetol phosphate aminotransferase(hisHb), and cyclohexadienyl dehydrogenase (tyrAc) genes, complete cds; and5-enolpyruvylshikmate 3-P synthase (aroF) gene, partial cds; TREMBL:AF038578_3. (277 aa)
Ta0937prolyl-tRNA synthetase related protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (462 aa)
Ta0942glutamyl-tRNA synthetase related protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (550 aa)
Ta0944GMP synthase related protein; Catalyzes the synthesis of GMP from XMP. (181 aa)
Ta0946aspartyl-tRNA synthetase related protein; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (428 aa)
Ta0947Similarity to known protein: beta-hydroxybutyryl-CoA dehydrogenase, NAD-dependent (EC 1.1.1.-) - Clostridium acetobutylicum; PIR:A43723Function: poly beta-hydroxybutyrate biosynthesis. (314 aa)
Ta0952Probable malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (325 aa)
Ta0972L-asparaginase related protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (409 aa)
Ta0977Methionine synthase (cobalamin-independent) related protein; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown (By similarity). (343 aa)
Ta0979Similarity to known protein: 5, 10-METHYLENETETRAHYDROFOLATE REDUCTASE (EC 1.7.99.5) - Streptomyces lividans; SWISSPROT:METF_STRLI. (270 aa)
Ta0987Similarity to known protein: Giardia intestinalis arginine deiminase gene, complete cds; TREMBL:GI49236_1. (418 aa)
Ta1012Indolepyruvate ferredoxin oxidoreductase, alpha subunit related protein; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (605 aa)
Ta1075Probable 3-phosphoglycerate kinase; Strong similarity to known protein: phosphoglycerate kinase (EC 2.7.2.3) [validated] - Methanothermus fervidus (fragment); PIR:PN0008. (408 aa)
Ta0886Strong similarity to unknown protein: pyruvate, orthophosphate dikinase (EC 2.7.9.1) - Thermotoga maritima (strain MSB8); PIR:F72397Function: Pyruvate metabolism, Carbon ixation. (886 aa)
Ta0882Enolase related protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa)
Ta0879isoleucyl-tRNA synthetase related protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1014 aa)
Ta0849alanyl-tRNA synthetase related protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (871 aa)
Ta0824Probable chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (360 aa)
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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