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| | Ta0081 | Conserved hypothetical protein; Similarity to unknown protein: thymidylate kinase (tmk) homolog - Archaeoglobus fulgidus; PIR:E69257. (193 aa) |
| | Ta0119 | RIBOSE-PHOSPHATE PYROPHOSPHOKINASE related protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (237 aa) |
| | Ta0107 | Conserved hypothetical membrane protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (176 aa) |
| | Ta1480 | Similarity to known protein: Homo sapiens molybdopterin-synthase small and large subunit (MOCS2)bicistronic mRNA, complete cds; TREMBL:AF091871_2. (135 aa) |
| | Ta1451 | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] (457 aa) |
| | Ta1431 | Conserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP). (220 aa) |
| | Ta1429 | Similarity to unknown protein: hypothetical protein CT632 - Chlamydia trachomatis (serotype D, strain UW3/Cx); PIR:D71489; Belongs to the UPF0159 family. (499 aa) |
| | Ta1367 | Probable adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (460 aa) |
| | Ta1361 | Probable GMP synthase; Catalyzes the synthesis of GMP from XMP. (310 aa) |
| | Ta1350 | Probable carbamate kinase; Strong similarity to known protein: CARBAMATE KINASE (EC 2.7.2.2) - Clostridium perfringens; SWISSPROT:ARCC_CLOPEFunction: amino acid fermantation. (339 aa) |
| | Ta1347 | Hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. (214 aa) |
| | Ta1319 | Cad protein (human), dihydroorotase domain related protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (414 aa) |
| | Ta0073 | Orotidine-5'-monophosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (215 aa) |
| | Ta0060 | Similarity to known protein: purH bifunctional enzyme - Escherichia coli; PIR:DTECPH. (491 aa) |
| | Ta0056 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (171 aa) |
| | Ta0047 | Similarity to known protein: anaerobic sulfite reduction protein B - Salmonella typhimurium; PIR:B38453Function: potentially a sulfite reduction protein. ORF_prediction: A related proteins is more than 25 aa longer, this ORF possibly only 7 aa longer due to genomic organization, sticked to prediction. (244 aa) |
| | Ta0622 | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (272 aa) |
| | Ta0616 | Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (223 aa) |
| | Ta0598 | dCTP deaminase related protein; Catalyzes the deamination of dCTP to dUTP. (183 aa) |
| | Ta0594 | Similarity to known protein: phosphoribosylamine--glycine ligase (EC 6.3.4.13) - Methanococcus jannaschii; PIR:A64417. (205 aa) |
| | Ta0575 | Strong similarity to known protein: probable aspartate carbamoyltransferase catalytic chain - Pyrococcus horikoshii; PIR:A71119. (305 aa) |
| | Ta0574 | Probable aspartate carbamoyltransferase, regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. (151 aa) |
| | Ta0570 | Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (166 aa) |
| | Ta0569 | Similarity to unknown proteinFunction: glycerolipid metabolism; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (222 aa) |
| | Ta0530 | Homoserine kinase related protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (310 aa) |
| | Ta0526 | Thiamine monophosphate kinase related protein; Similarity to known protein: thiamin monphosphate kinase - Methanobacterium thermoautotrophicum (strain Delta H); PIR:G69052. (275 aa) |
| | Ta0523 | Strong similarity to known protein: adenylosuccinate lyase (EC 4.3.2.2) - Bacillus subtilis; PIR1:WZBSDSFunction: Purine metabolism, Alanine and Aspartate metabolism. (455 aa) |
| | Ta0522 | Probable pyridoxine biosynthesis pyroA protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (336 aa) |
| | Ta0516 | Geranylgeranyl reductase related protein; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. Can use both NADH and NADPH as electron donors. Also catalyzes the reduction of the naturally occurring 2,3-di-O-geranylgeranylgly [...] (389 aa) |
| | Ta0506 | Thiazole biosynthesis protein Thi I related protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (469 aa) |
| | Ta0493 | Similarity to known protein: MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN B - Escherichia coli; SWISSPROT:MOAB_ECOLI. (162 aa) |
| | Ta0492 | Molybdopterin biosynthesis protein MoaC related protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (143 aa) |
| | Ta0488 | Weak similarity to unknown protein. Relation: similarity to protein kinases. (409 aa) |
| | Ta0486 | Uridylate kinase related protein; Catalyzes the reversible phosphorylation of UMP to UDP. (229 aa) |
| | Ta0453 | Glycerate kinase related protein; Similarity to known protein: Methylobacterium extorquens putative glycerate kinase and pyruvate kinase(pykA) genes, complete cds; TREMBLNEW:MEU87316_4. (396 aa) |
| | Ta0443 | Molybdopterin biosynthesis protein moaA related protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (324 aa) |
| | Ta0423 | Conserved hypothetical protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (282 aa) |
| | Ta0421 | Probable acetyl-coenzyme-A synthetase; Strong similarity to known protein: acetate--CoA ligase (EC 6.2.1.1) [validated] - Methanothrix soehngenii; PIR:A41043. (647 aa) |
| | Ta0413 | Conserved hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (404 aa) |
| | Ta0406 | Similarity to known protein: hydroxymethylglutaryl-CoA reductase (EC 1.1.1.88) - Pseudomonas sp; PIR:A44756. (437 aa) |
| | Ta0404 | DIHYDROOROTATE DEHYDROGENASE B related protein; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. (300 aa) |
| | Ta0403 | Nife hydrogenase gamma subunit related protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (250 aa) |
| | Ta0399 | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (179 aa) |
| | Ta0396 | RIO1 protein related; Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). (186 aa) |
| | Ta0364 | Similarity to known protein: A.thaliana mRNA for aspartate kinase; TREMBL:ATAKLYS1_1. (272 aa) |
| | Ta0325 | HAM1 protein related; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (187 aa) |
| | Ta0324 | O-sialoglycoprotein endopeptidase related protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr pro [...] (529 aa) |
| | Ta0313 | Triosephosphate isomerase related protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (216 aa) |
| | Ta1318 | Phosphoribosylformylglycinamidine synthase I related protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is tho [...] (289 aa) |
| | Ta1315 | Probable ribulose-5-phosphate 3-epimerase; Strong similarity to known protein: RIBULOSE-PHOSPHATE 3-EPIMERASE PRECURSOR (EC 5.1.3.1) (PENTOSE-5-PHOSPHATE 3-EPIMERASE) (PPE) (RPE) (R5P3E) - Oryza sativa (Rice); SWISSPROT:RPE_ORYSA. (211 aa) |
| | Ta1305 | Hypothetical protein; Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, only present in extreme acidophiles of the Thermoplasmatales order, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. (318 aa) |
| | Ta1281 | Strong similarity to known protein: PHOSPHOMETHYLPYRIMIDINE KINASE (EC 2.7.4.7) (HMP-PHOSPHATE KINASE)(HMP-P KINASE).PHOSPHOMETHYLPYRIMIDINE KINASE (EC 2.7.4.7) (HMP-PHOSPHATE KINASE)(HMP-P KINASE) - Salmonella typhimurium.Salmonella typhimurium; SWISSPROT:THID_SALTY. (263 aa) |
| | Ta1277 | Thiamine phosphate pyrophosphorylase (yeast THI6) related protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (213 aa) |
| | Ta1247 | Probable adenylate kinase; Strong similarity to known protein: ADENYLATE KINASE (EC 2.7.4.3) (ATP-AMP TRANSPHOSPHORYLASE) - Methanococcus igneus; SWISSPROT:KAD_METIG; Belongs to the archaeal adenylate kinase family. (183 aa) |
| | Ta1245 | Probable cytidylate kinase; Strong similarity to known protein: CYTIDYLATE KINASE (EC 2.7.4.14) (CK) (CYTIDINE MONOPHOSPHATE KINASE)(CMP KINASE).CYTIDYLATE KINASE (EC 2.7.4.14) (CK) (CYTIDINE MONOPHOSPHATE KINASE)(CMP KINASE) - Sulfolobus acidocaldarius.Sulfolobus acidocaldarius; SWISSPROT:KCY_SULAC. (188 aa) |
| | Ta1242 | Probable amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (474 aa) |
| | Ta1214 | Similarity to known protein: Canarypox virus gene for thymidine kinase and 8 ORFs, partial and completecds; TREMBL:D86731_5. (186 aa) |
| | Ta1194 | Conserved hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. In the N-terminal section; belongs to the eukaryotic CoaD family. (328 aa) |
| | Ta1158 | Glycerol 1-phosphate dehydrogenase related protein; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. (352 aa) |
| | Ta1145 | Conserved hypothetical protein; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. Highly divergent. (392 aa) |
| | Ta1139 | Aut related protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (142 aa) |
| | Ta1113 | Probable nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (148 aa) |
| | Ta1107 | Phosphoribosylaminoimidazole carboxylase related protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (360 aa) |
| | Ta1103 | Strong similarity to known protein: glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Methanothermus fervidus; PIR:JT0286. (338 aa) |
| | Ta1096 | Probable glycerol kinase; Strong similarity to known protein: GLYCEROL KINASE (EC 2.7.1.30) (ATP:GLYCEROL 3-PHOSPHOTRANSFERASE)(GLYCEROKINASE) (GK) - Thermus aquaticus (subsp. flavus); SWISSPROT:GLPK_THEFL. (488 aa) |
| | Ta1091 | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (156 aa) |
| | Ta1075 | Probable 3-phosphoglycerate kinase; Strong similarity to known protein: phosphoglycerate kinase (EC 2.7.2.3) [validated] - Methanothermus fervidus (fragment); PIR:PN0008. (408 aa) |
| | Ta1068 | Strong similarity to unknown protein: hypothetical protein APE1825 - Aeropyrum pernix (strain K1); PIR:G72567. (354 aa) |
| | Ta1066 | Phosphoribosylformylglycinamidine synthase related protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thoug [...] (759 aa) |
| | Ta1064 | Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (220 aa) |
| | Ta1044 | Conserved hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer [...] (84 aa) |
| | Ta1023 | Similarity to known protein: molybdopterin biosynthesis protein moeA - Escherichia coli; PIR:A32352. (399 aa) |
| | Ta1022 | Similarity to known protein: MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN (MOLYBDENUM COFACTORBIOSYNTHESIS ENZYME CNX1) - Arabidopsis thaliana (Mouse-ear cress); SWISSPROT:CNX1_ARATH. (626 aa) |
| | Ta1019 | MoaD (involved in molybdopterin synthesis) related protein; Similarity to known protein: Mus musculus molybdopterin-synthase small and large subunit (Mocs2)bicistronic mRNA, complete cds; TREMBL:AF091872_1. (85 aa) |
| | Ta0995 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. Cannot use sn-glycerol-3-phosphate (G3P) as substrate. Belongs to the GGGP/HepGP synthase family. Group II subfamily. (253 aa) |
| | Ta0944 | GMP synthase related protein; Catalyzes the synthesis of GMP from XMP. (181 aa) |
| | Ta0899 | NAD(+) synthase related protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (241 aa) |
| | Ta0898 | Methylenetetrahydrofolate dehydrogenase (NADP+) related protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (276 aa) |
| | Ta0896 | Similarity to known protein: pyruvate kinase (EC 2.7.1.40) [validated] - Bacillus licheniformis; PIR:JC4220. (544 aa) |
| | Ta0893 | Hypothetical protein; Catalyzes the ATP-independent decarboxylation of (R)- mevalonate 3,5-bisphosphate to isopentenyl phosphate. Functions in an alternative mevalonate pathway, only present in extreme acidophiles of the Thermoplasmatales order, which passes through mevalonate 3- phosphate rather than mevalonate 5-phosphate. (405 aa) |
| | Ta0001 | ATP synthase (subunit E) related protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (185 aa) |
| | Ta0002 | ATP synthase (subunit C) related protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (356 aa) |
| | Ta0003 | ATP synthase(subunit F) related protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (104 aa) |
| | Ta0004 | Probable ATP synthase, subunit A (intein containing); Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit; Belongs to the ATPase alpha/beta chains family. (764 aa) |
| | Ta0005 | Probable ATP synthase (subunit B); Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (476 aa) |
| | Ta0006 | Vacuolar proton-ATPase subunit D related protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (213 aa) |
| | Ta0009 | Hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (203 aa) |
| | Ta0039 | Weak similarity to known protein. (154 aa) |
| | Ta0044 | Probable CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (540 aa) |
| | Ta0103 | Gamma-glutamyl kinase related protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has lower activity with isopentenyl thiolophosphate (ISP). Has low activity with dimethylallyl phosphate (DMAP), 1-butyl phosphate (BP) and 3-buten-1-yl phosphate (BEP). Has no significant activity with geranyl phosphate (in vitro). Belongs to the isopentenyl phosphate kinase family. (245 aa) |
| | Ta0090 | Probable phosphoribosyl-aminoimidazole synthetase; Strong similarity to known protein: Lactococcus lactis cremoris ClpB chaperone homolog (clpB) and phosphoribosylformylglycinamide cyclo-ligase (pur5) genes, complete cds;and phosphoribosylglycinamide formyltransferase (pur3) gene, partial cds; TREMBL:AF016634_2. (338 aa) |
| | Ta0082 | Strong similarity to known protein: phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) - Arabidopsis thaliana; PIR:S37105. (203 aa) |
| | Ta0633 | Similarity to known protein: glycerol-3-phosphate dehydrogenase (EC 1.1.99.5) chain A, anaerobic [validated] - Escherichia coli; PIR:DEECNA. (422 aa) |
| | Ta0684 | Deoxyribose-phosphate aldolase related protein; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (246 aa) |
| | Ta0762 | 2-phosphoglycerate kinase related protein; Phosphorylates mevalonate 3-phosphate to form mevalonate 3,5- bisphosphate. Functions in an alternative mevalonate pathway, only present in extreme acidophiles of the Thermoplasmatales order, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. (202 aa) |
| | Ta0774 | Strong similarity to unknown protein: hypothetical protein MJ0541 - Methanococcus jannaschii; PIR:E64367. (180 aa) |
| | Ta0791 | Probable carbamoyl-phosphate synthase, large subunit; Strong similarity to known protein: carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus; PIR:I40169. (1047 aa) |
| | Ta0792 | Similarity to known protein: carbamoyl-phosphate synthase, small (or glutamine) subunit (carA) homolog - Archaeoglobus fulgidus; PIR:H69408Function: Urea cycle and metabolism of amino groups, Glutamate metabolism, Arginine and proline metabolism, Nitrogen metabolism; Belongs to the CarA family. (353 aa) |
| | Ta0809 | Probable aldehyde dehydrogenase; NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes. (493 aa) |
| | Ta0825 | Glucose kinase related protein; Similarity to known protein: Bacillus megaterium glk gene; TREMBL:BMGLUCKIN_2. (324 aa) |
| | Ta0854 | Probable phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (182 aa) |
| | Ta0865 | ABC transporter related protein; Similarity to known protein: UBIQUINONE BIOSYNTHESIS PROTEIN AARF (AMINOGLYCOSIDE ACETYLTRANSFERASEREGULATOR) - Providencia stuartii; SWISSPROT:AARF_PROST. (504 aa) |
| | Ta0878 | Ribose-5-phosphate isomerase related protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (241 aa) |
| | Ta0880 | Ribokinase related protein; Nucleoside kinase with broad substrate specificity. Catalyzes the phosphorylation of a variety of nucleosides to the corresponding nucleoside 5'-mono-phosphate in the presence of phosphate donors and divalent cations. Displays the most efficient activity with guanosine, followed by inosine, cytidine, and adenosine. Negligible enzymatic activity is detected with thymidine, uridine, and 2-deoxyadenosine. ATP is the most efficient phosphate donor, but can also use GTP and ITP. Shows no sugar kinase activity, since it is unable to phosphorylate ribose, fructose- [...] (287 aa) |
| | Ta0882 | Enolase related protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa) |
| | Ta0886 | Strong similarity to unknown protein: pyruvate, orthophosphate dikinase (EC 2.7.9.1) - Thermotoga maritima (strain MSB8); PIR:F72397Function: Pyruvate metabolism, Carbon ixation. (886 aa) |
| | Ta0889 | DNA/pantothenate metabolism flavoprotein related protein; Similarity to known protein: Bradyrhizobium japonicum UbiE (ubiE) gene, partial cds; AarF (aarF), panthotenate metabolism flavoprotein (dfp), deoxyuridine-triphosphatase(dut), putative sensor protein (bdfA), GalF-like (galF), hypotheticalprotein genes, complete cds; putative helicase 2 gene, partial cds; andunknown genes; TREMBL:AF042096_2. (394 aa) |
| | Ta0122 | Xylulose kinase related protein; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Is specific for KDG. (336 aa) |
| | Ta0175 | Conserved hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate. Also has significant, but less efficient, pyrophosphatase activity, since it is able to catalyze the release of phosphate from inorganic pyrophosphate (PPi); Belongs to the HAD-like hydrolase superfamily. Archaeal SPP-like hydrolase family. (224 aa) |
| | Ta0219 | Probable inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | Ta0283 | Conserved hypothetical protein; Similarity to unknown protein: homoserine kinase PAB0301 - Pyrococcus abyssi (strain Orsay); PIR:F75161. (268 aa) |
| | Ta0303 | Probable phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (160 aa) |
| | Ta0309 | Similarity to known protein: PHOSPHORIBOSYLAMIDOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (EC 6.3.2.6)(SAICAR SYNTHETASE) - Saccharomyces cerevisiae (Baker's yeast); SWISSPROT:PUR7_YEAST. (314 aa) |
| | Ta0312 | Probable dCMP deaminase; Strong similarity to known protein: Yeast (S.cerevisiae) dCMP deaminase gene (DCD1), complete cds; TREMBL:SCDCD1_1. (170 aa) |
