STRINGSTRING
Ta1103 Ta1103 Ta1419 Ta1419 Ta1428 Ta1428 Ta0085 Ta0085 Ta0123 Ta0123 Ta0568 Ta0568 Ta0635 Ta0635 Ta0776 Ta0776 Ta0809 Ta0809 Ta0882 Ta0882
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ta1103Strong similarity to known protein: glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Methanothermus fervidus; PIR:JT0286. (338 aa)
Ta1419Conserved hypothetical protein; Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency; Belongs to the PGI/PMI family. (310 aa)
Ta1428Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (375 aa)
Ta0085Conserved hypothetical protein. (386 aa)
Ta0123Probable phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (614 aa)
Ta0568Similarity to known protein: phosphomannomutase (pmm) homolog - Archaeoglobus fulgidus; PIR:B69307; Belongs to the phosphohexose mutase family. (453 aa)
Ta0635Strong similarity to known protein: GLUTAMATE DEHYDROGENASE (EC 1.4.1.3) (GDH) - Thermococcus litoralis; SWISSPROT:DHE3_THELIFunction: generally involved with either ammonia assimilation or glutamate catabolism. ORF_prediction: N-terminus longer than those of trelated proteins, however its codon usage does support a coding function of the first 40 aa, the frequency of rare codons is very low, possible second start only after 35 aa, not altered; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (436 aa)
Ta0776Strong similarity to known protein: GLUTAMATE DEHYDROGENASE (EC 1.4.1.3) (GDH) - Pyrococcus horikoshii; SWISSPROT:DHE3_PYRHO; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa)
Ta0809Probable aldehyde dehydrogenase; NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes. (493 aa)
Ta0882Enolase related protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa)
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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