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| | Ta0010 | Strong similarity to known protein: aminomethyltransferase (EC 2.1.2.10) [validated] - Escherichia coli; PIR:A56689Function: Glycine, serine and threonine metabolism, One carbon pool by folate, Nitrogen metabolism. (336 aa) |
| | Ta0026 | Similarity to known protein: threonine synthase (EC 4.2.99.2) thrC - Bacillus subtilis; PIR2:A25364Function: Glycine, serine and threonine metabolism. (316 aa) |
| | Ta0030 | Probable acetyl CoA synthase; Strong similarity to known protein: P.furiosus vorA, vorB, vorD, porA, porB, porC, porD and ORFZ genes; TREMBL:PFPORVOR_4Function: Reductive carboxylate cycle (CO2 fixation). (391 aa) |
| | Ta0059 | Conserved hypothetical protein; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (400 aa) |
| | Ta0060 | Similarity to known protein: purH bifunctional enzyme - Escherichia coli; PIR:DTECPH. (491 aa) |
| | Ta0080 | Similarity to known protein: cystathionine gamma-lyase (EC 4.4.1.1) - rat; PIR:A49864Function: Methionine metabolism, Selenoamino acid metabolism, Nitrogen metabolism. (384 aa) |
| | Ta0082 | Strong similarity to known protein: phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) - Arabidopsis thaliana; PIR:S37105. (203 aa) |
| | Ta0090 | Probable phosphoribosyl-aminoimidazole synthetase; Strong similarity to known protein: Lactococcus lactis cremoris ClpB chaperone homolog (clpB) and phosphoribosylformylglycinamide cyclo-ligase (pur5) genes, complete cds;and phosphoribosylglycinamide formyltransferase (pur3) gene, partial cds; TREMBL:AF016634_2. (338 aa) |
| | Ta0102 | Conserved hypothetical protein; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (348 aa) |
| | Ta0103 | Gamma-glutamyl kinase related protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has lower activity with isopentenyl thiolophosphate (ISP). Has low activity with dimethylallyl phosphate (DMAP), 1-butyl phosphate (BP) and 3-buten-1-yl phosphate (BEP). Has no significant activity with geranyl phosphate (in vitro). Belongs to the isopentenyl phosphate kinase family. (245 aa) |
| | Ta0112 | Strong similarity to known protein: aconitate hydratase (EC 4.2.1.3) - Legionella pneumophila; PIR:B48642. (869 aa) |
| | Ta0113 | Strong similarity to known protein: threonine dehydratase (EC 4.2.1.16), biodegradative [validated] - Escherichia coli; PIR:DWECTD. (406 aa) |
| | Ta0116 | Hypothetical protein; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (228 aa) |
| | Ta0117 | Strong similarity to known protein: isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) - Bacillus subtilis; PIR:I40382. (405 aa) |
| | Ta0119 | RIBOSE-PHOSPHATE PYROPHOSPHOKINASE related protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (237 aa) |
| | Ta0123 | Probable phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (614 aa) |
| | Ta0139 | Pyrroline-5-carboxylate reductase related protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (279 aa) |
| | Ta0169 | Known protein: citrate (si)-synthase (EC 4.1.3.7) - Thermoplasma acidophilum; PIR:YKYT. (385 aa) |
| | Ta0174 | Conserved hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (271 aa) |
| | Ta0175 | Conserved hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate. Also has significant, but less efficient, pyrophosphatase activity, since it is able to catalyze the release of phosphate from inorganic pyrophosphate (PPi); Belongs to the HAD-like hydrolase superfamily. Archaeal SPP-like hydrolase family. (224 aa) |
| | Ta0208 | Similarity to known protein: dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Escherichia coli; PIR:DEECLP. (451 aa) |
| | Ta0215 | Conserved hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (365 aa) |
| | Ta0219 | Probable inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | Ta0229 | acetyl-CoA synthetase related protein; Similarity to known protein: acetate--CoA ligase (EC 6.2.1.1) - Emericella nidulans; PIR:SYASAA. (619 aa) |
| | Ta0247 | Strong similarity to known protein: Synechocystis sp. ccmA gene for 32.4kD protein and ORF271 for 29.5kDprotein, complete cds; TREMBL:SSCCMA_1. (285 aa) |
| | Ta0249 | Probable N-acylamino acid racemase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (361 aa) |
| | Ta0251 | Similarity to known protein: Bacillus subtilis PlsX (plsX), malonyl-CoA:Acyl carrier proteintransacylase (fabD) and 3-ketoacyl-acyl carrier protein reductase (fabG)genes, complete cds, and acyl carrier protein (acpP) gene, partial cds; TREMBL:BSU59433_3. (255 aa) |
| | Ta0258 | Probable fumarase; Strong similarity to known protein: Bacillus subtilis 42.7kB DNA fragment from yvsA to yvqA; TREMBLNEW:BS43KBDNA_39. (457 aa) |
| | Ta0259 | Probable pyruvate ferredoxin oxidoreductase, alpha subunit; Strong similarity to known protein: 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain [validated] - Sulfolobus sp. (strain 7); PIR:JC4919. (588 aa) |
| | Ta0260 | Probable pyruvate ferredoxin oxidoreductase, beta subunit; Strong similarity to known protein: 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) beta chain - Methanobacterium thermoautotrophicum (strain Delta H); PIR:H69170. (285 aa) |
| | Ta0282 | 3-phosphoshikimate 1-carboxyvinyltransferase related protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (410 aa) |
| | Ta0283 | Conserved hypothetical protein; Similarity to unknown protein: homoserine kinase PAB0301 - Pyrococcus abyssi (strain Orsay); PIR:F75161. (268 aa) |
| | Ta0284 | Shikimate 5-dehydrogenase related protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (268 aa) |
| | Ta0285 | 3-dehyroquinate synthase related protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (360 aa) |
| | Ta0296 | Strong similarity to known protein: acetyl-CoA C-acetyltransferase (EC 2.3.1.9) [validated] - Clostridium acetobutylicum; PIR:JC4032. (396 aa) |
| | Ta0298 | Similarity to known protein: ALPHA-GLUCOSIDASE (EC 3.2.1.20) (MALTASE).ALPHA-GLUCOSIDASE (EC 3.2.1.20) (MALTASE) - Sulfolobus solfataricus.Sulfolobus solfataricus; SWISSPROT:AGLU_SULSO; Belongs to the glycosyl hydrolase 31 family. (749 aa) |
| | Ta0303 | Probable phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (160 aa) |
| | Ta0309 | Similarity to known protein: PHOSPHORIBOSYLAMIDOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (EC 6.3.2.6)(SAICAR SYNTHETASE) - Saccharomyces cerevisiae (Baker's yeast); SWISSPROT:PUR7_YEAST. (314 aa) |
| | Ta0310 | Uroporphyrinogen decarboxylase related protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (333 aa) |
| | Ta0311 | Ferrochelatase related protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (308 aa) |
| | Ta0313 | Triosephosphate isomerase related protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (216 aa) |
| | Ta0315 | Similarity to known protein: Mus musculus asparagine synthetase mRNA, complete cds; TREMBL:MM38940_1. (236 aa) |
| | Ta0338 | Similarity to known protein: Lupinus luteus L-asparaginase mRNA, complete cds; TREMBL:AF112444_1. (274 aa) |
| | Ta0351 | Similarity to known protein: sterol carrier protein x - mouse; PIR2:JU0157. (437 aa) |
| | Ta0363 | Similarity to known protein: Ustilgo maydis aspartate semialdehyde dehydrogenase (ASADH) mRNA, completecds; TREMBL:UM44901_1. (338 aa) |
| | Ta0364 | Similarity to known protein: A.thaliana mRNA for aspartate kinase; TREMBL:ATAKLYS1_1. (272 aa) |
| | Ta0398 | Similarity to known protein: ACYL-COA DEHYDROGENASE, SHORT-CHAIN SPECIFIC (EC 1.3.99.2)(SCAD) (BUTYRYL-COA DEHYDROGENASE) - Clostridium acetobutylicum; SWISSPROT:ACDS_CLOABFunction: Fatty acid metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism. (395 aa) |
| | Ta0406 | Similarity to known protein: hydroxymethylglutaryl-CoA reductase (EC 1.1.1.88) - Pseudomonas sp; PIR:A44756. (437 aa) |
| | Ta0413 | Conserved hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (404 aa) |
| | Ta0414 | Similarity to known protein: GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN (EC 1.4.1.13) (GLUTAMATESYNTHASE BETA SUBUNIT) (NADPH-GOGAT) (GLTS BETA CHAIN) - Escherichia coli; SWISSPROT:GLTD_ECOLI. (484 aa) |
| | Ta0421 | Probable acetyl-coenzyme-A synthetase; Strong similarity to known protein: acetate--CoA ligase (EC 6.2.1.1) [validated] - Methanothrix soehngenii; PIR:A41043. (647 aa) |
| | Ta0435 | Heme A: farnesyltransferase related protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (288 aa) |
| | Ta0436 | Similarity to known protein: BIFUNCTIONAL SHORT CHAIN ISOPRENYL DIPHOSPHATE SYNTHASE [INCLUDES:FARNESYL PYROPHOSPHATE SYNTHETASE (EC 2.5.1.1) (FPP SYNTHETASE)(DIMETHYLALLYLTRANSFERASE); GERANYLTRANSTRANSFERASE (EC 2.5.1.10)] - Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133); SWISSPROT:IDSA_METTM. (322 aa) |
| | Ta0439 | Piperideine-6-carboxilic acid dehydrogenase related protein; Strong similarity to known protein: Malus domestica mRNA for protein abundantly expressed during apple fruitdevelopment, complete cds; TREMBL:D88434_1. Relation: strong similarity to a protein abundantly expressed during apple fruit development, function not known, TREMBL:D88434_1. (512 aa) |
| | Ta0441 | 3-oxoacyl-[acyl-carrier-protein] reductase related protein; Similarity to known protein: Bacillus subtilis PlsX (plsX), malonyl-CoA:Acyl carrier proteintransacylase (fabD) and 3-ketoacyl-acyl carrier protein reductase (fabG)genes, complete cds, and acyl carrier protein (acpP) gene, partial cds; TREMBL:BSU59433_3. (250 aa) |
| | Ta0453 | Glycerate kinase related protein; Similarity to known protein: Methylobacterium extorquens putative glycerate kinase and pyruvate kinase(pykA) genes, complete cds; TREMBLNEW:MEU87316_4. (396 aa) |
| | Ta0495 | Similarity to known protein: threonine synthase (EC 4.2.99.2) thrC - Bacillus subtilis; PIR:A25364. (334 aa) |
| | Ta0523 | Strong similarity to known protein: adenylosuccinate lyase (EC 4.3.2.2) - Bacillus subtilis; PIR1:WZBSDSFunction: Purine metabolism, Alanine and Aspartate metabolism. (455 aa) |
| | Ta0529 | Probable aspartate aminotransferase; Strong similarity to known protein: aspartate transaminase (EC 2.6.1.1) - Sulfolobus solfataricus; PIR:S07088Function: Glutamate metabolism, Alanine and Aspartate metabolism Cysteine metabolism, Carbon fixation. (377 aa) |
| | Ta0530 | Homoserine kinase related protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (310 aa) |
| | Ta0531 | Probable cystathionine gamma-synthase; Strong similarity to known protein: Arabidopsis thaliana gene for cystathionine gamma-synthase, complete cds; TREMBL:AB010888_1Function: Involved in Cysteine metabolism, Methionine metabolism, Glycine, serine and threonine metabolism, Selenoamino acid metabolism. EC Numbers and enzyme names are mixed up, homologs are called cystathionine gamma-synthase (EC 4.2.99.9) and cystathionine gamma lyase (EC 4.4.1.-). (380 aa) |
| | Ta0535 | Similarity to known protein: cysteine synthase (EC 4.2.99.8) B - Campylobacter jejuni; PIR:JC6185. (299 aa) |
| | Ta0536 | glutamyl-tRNA reductase related protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (409 aa) |
| | Ta0542 | Probable D-lactate dehydrogenase; Strong similarity to known protein: glycolate oxidase subunit (glcD) homolog - Archaeoglobus fulgidus; PIR:H69350. (466 aa) |
| | Ta0568 | Similarity to known protein: phosphomannomutase (pmm) homolog - Archaeoglobus fulgidus; PIR:B69307; Belongs to the phosphohexose mutase family. (453 aa) |
| | Ta0570 | Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (166 aa) |
| | Ta0571 | Strong similarity to known protein: glutamate-1-semialdehyde 2, 1-aminomutase (EC 5.4.3.8) - common tobacco; PIR:S21455; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (426 aa) |
| | Ta0572 | Porphobilinogen deaminase related protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (295 aa) |
| | Ta0573 | Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (225 aa) |
| | Ta0576 | Similarity to known protein: protoporphyrin IX magnesium chelatase (EC 4.99.1.-) ChlI - Methanobacterium thermoautotrophicum (strain Delta H); PIR:E69173. (617 aa) |
| | Ta0582 | Strong similarity to known protein: acetyl-CoA C-acetyltransferase (EC 2.3.1.9) [validated] - Clostridium acetobutylicum; PIR:JC4032. (388 aa) |
| | Ta0594 | Similarity to known protein: phosphoribosylamine--glycine ligase (EC 6.3.4.13) - Methanococcus jannaschii; PIR:A64417. (205 aa) |
| | Ta0595 | Similarity to known protein: phosphoribosylamine--glycine ligase (EC 6.3.4.13) [validated] - Bacillus subtilis; PIR:AJBSAG. (219 aa) |
| | Ta0616 | Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (223 aa) |
| | Ta0617 | Probable transketolase; Strong similarity to known protein: TRANSKETOLASE (EC 2.2.1.1) (TK) (P68) - Mus musculus (Mouse); SWISSPROT:TKT_MOUSE. (316 aa) |
| | Ta0618 | Probable transketolase; Strong similarity to known protein: TRANSKETOLASE (EC 2.2.1.1) (TK) (P68) - Mus musculus (Mouse); SWISSPROT:TKT_MOUSE. (273 aa) |
| | Ta0626 | Strong similarity to known protein: PYRUVATE/KETOISOVALERATE OXIDOREDUCTASES COMMON GAMMA SUBUNIT[INCLUDES: PYRUVATE SYNTHASE SUBUNIT PORC (EC 1.2.7.1) (PYRUVATEOXIDOREDUCTASE GAMMA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASEGAMMA SUBUNIT); KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORC(EC 1.-.-.-) (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE GAMMA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE GAMMA SUBUNIT)] - Pyrococcus furiosus; SWISSNEW:PORC_PYRFUFunction: Pyruvate metabolism, Propanoate metabolism, Butanoate metabolism, Reductive carboxylate cycle (CO2 fixation). (195 aa) |
| | Ta0631 | Similarity to known protein: probable coenzyme PQQ synthesis protein APE1655 - Aeropyrum pernix (strain K1); PIR:C72546. Relation: similarity found to heme biosynthesis protein - Archaeoglobus fulgidus, PIR:H69500. (401 aa) |
| | Ta0633 | Similarity to known protein: glycerol-3-phosphate dehydrogenase (EC 1.1.99.5) chain A, anaerobic [validated] - Escherichia coli; PIR:DEECNA. (422 aa) |
| | Ta0649 | Similarity to known protein: argininosuccinate lyase (EC 4.3.2.1) - goose; PIR:JN0486. (433 aa) |
| | Ta0650 | Strong similarity to known protein: argininosuccinate synthase (EC 6.3.4.5) - Methanococcus vannielii; PIR:AJMXRV; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa) |
| | Ta0652 | Hypothetical protein. (210 aa) |
| | Ta0653 | S-adenosyl-L-methionine uroporphyrinogen methyltransferase related protein; Similarity to known protein: uroporphyrin-III C-methyltransferase (EC 2.1.1.107) [validated] - Methanobacterium ivanovii; PIR:A42471. (246 aa) |
| | Ta0669 | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (424 aa) |
| | Ta0674 | Conserved hypothetical protein; Weak similarity to unknown protein. (275 aa) |
| | Ta0691 | Acetolactate synthase, large chain related protein; Similarity to known protein: acetolactate synthase (EC 4.1.3.18) - Caulobacter crescentus; PIR:I40666. Relation: similarity to acetolactate synthase (EC 4.1.3.18) - Caulobacter crescentus; I40666. Function: Valine, leucine and isoleucine biosynthesis, Butanoate metabolism, C5-Branched dibasic acid metabolism, Pantothenate and CoA biosynthesis. (553 aa) |
| | Ta0762 | 2-phosphoglycerate kinase related protein; Phosphorylates mevalonate 3-phosphate to form mevalonate 3,5- bisphosphate. Functions in an alternative mevalonate pathway, only present in extreme acidophiles of the Thermoplasmatales order, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. (202 aa) |
| | Ta0769 | Probable acetyl-coenzyme A synthetase; Strong similarity to known protein: acetate--CoA ligase (EC 6.2.1.1) [validated] - Methanothrix soehngenii; PIR:A41043. (599 aa) |
| | Ta0772 | Strong similarity to known protein: 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) beta chain - Sulfolobus sp. (strain 7); PIR:JC4920. (309 aa) |
| | Ta0773 | Strong similarity to known protein: 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain [validated] - Sulfolobus sp. (strain 7); PIR:JC4919. (629 aa) |
| | Ta0788 | Diaminopimelate decarboxylase related protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (436 aa) |
| | Ta0801 | Ubiquinone/menaquinone methyltransferase related protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (229 aa) |
| | Ta0803 | Similarity to known protein: TRYPTOPHAN SYNTHASE ALPHA CHAIN (EC 4.2.1.20).TRYPTOPHAN SYNTHASE ALPHA CHAIN (EC 4.2.1.20) - Sulfolobus solfataricus.Sulfolobus solfataricus; SWISSPROT:TRPA_SULSO. (217 aa) |
| | Ta0804 | Anthranilate phosphoribosyltransferase related protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (322 aa) |
| | Ta0805 | Weak similarity to known protein. Relation: weak similarity to phosphoribosylanthranilate isomerase - Aquifex aeolicus, PIR:A70478; Belongs to the TrpF family. (179 aa) |
| | Ta0806 | Similarity to known protein: anthranilate synthase (EC 4.1.3.27) component I - Clostridium thermocellum; PIR:JX0065. (356 aa) |
| | Ta0807 | Probable anthranilate synthase component II; Strong similarity to known protein: Pyrococcus kodakaraensis trp operon genes (trpC, trpD, trpE, trpG, trpF, trpB, trpA), complete cds; TREMBL:AB030011_4. (183 aa) |
| | Ta0808 | Similarity to known protein: indole-3-glycerol-phosphate synthase (EC 4.1.1.48) TrpC - Sulfolobus solfataricus; PIR:C40635; Belongs to the TrpC family. (237 aa) |
| | Ta0811 | Similarity to known protein: glycine hydroxymethyltransferase (EC 2.1.2.1) - Methanobacterium thermoautotrophicum (strain Marburg); PIR:S62190Function: involved in glycine, serine and threonine metabolism, also involved in vitamin B6 metabolism. (387 aa) |
| | Ta0819 | Probable citrate (si)-synthase; Strong similarity to known protein: CITRATE SYNTHASE (EC 4.1.3.7) - Thermoplasma acidophilum; SWISSPROT:CISY_THEAC. (391 aa) |
| | Ta0822 | Similarity to known protein: 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) precursor, NADPH-dependent [validated] - Cuphea lanceolata; PIR:S22450. (269 aa) |
| | Ta0823 | Weak similarity to known protein. (190 aa) |
| | Ta0824 | Probable chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (360 aa) |
| | Ta0825 | Glucose kinase related protein; Similarity to known protein: Bacillus megaterium glk gene; TREMBL:BMGLUCKIN_2. (324 aa) |
| | Ta0845 | Hypothetical protein; Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP). (208 aa) |
| | Ta0858 | Similarity to known protein: GLYCERATE DEHYDROGENASE (EC 1.1.1.29) (NADH-DEPENDENT HYDROXYPYRUVATEREDUCTASE) (HPR) (GDH) (HYDROXYPYRUVATE DEHYDROGENASE) (GLYOXYLATEREDUCTASE) (HPR-A) - Methylobacterium extorquens; SWISSPROT:DHGY_METEX; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (303 aa) |
| | Ta0878 | Ribose-5-phosphate isomerase related protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (241 aa) |
| | Ta0882 | Enolase related protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa) |
| | Ta0886 | Strong similarity to unknown protein: pyruvate, orthophosphate dikinase (EC 2.7.9.1) - Thermotoga maritima (strain MSB8); PIR:F72397Function: Pyruvate metabolism, Carbon ixation. (886 aa) |
| | Ta0893 | Hypothetical protein; Catalyzes the ATP-independent decarboxylation of (R)- mevalonate 3,5-bisphosphate to isopentenyl phosphate. Functions in an alternative mevalonate pathway, only present in extreme acidophiles of the Thermoplasmatales order, which passes through mevalonate 3- phosphate rather than mevalonate 5-phosphate. (405 aa) |
| | Ta0896 | Similarity to known protein: pyruvate kinase (EC 2.7.1.40) [validated] - Bacillus licheniformis; PIR:JC4220. (544 aa) |
| | Ta0897 | Glucose 1-dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Is also significantly active with galactose as substrate, but not with mannose or glucose 6-phosphate. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+). Physiologically, may be involved in the degradation of both glucose and galactose through a non-phosphorylative variant of the Entner-Doudoroff pathway; Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily. (361 aa) |
| | Ta0911 | Similarity to unknown protein: hypothetical 34K protein (glnA-fdhE intergenic region) - Escherichia coli; PIR:S40823. (288 aa) |
| | Ta0915 | Chorismate mutase/prephenate dehydratase related protein; Similarity to known protein: Pseudomonas stutzeri gyrase A subunit (gyrA) gene, partial cds;3-phosphoserine aminotransferase (serC), chorismate mutase/prephenatedehydratase (aroQp/pheA), imidazole acetol phosphate aminotransferase(hisHb), and cyclohexadienyl dehydrogenase (tyrAc) genes, complete cds; and5-enolpyruvylshikmate 3-P synthase (aroF) gene, partial cds; TREMBL:AF038578_3. (277 aa) |
| | Ta0936 | Conserved hypothetical protein; Weak similarity to known protein. Relation: similar to phosphoserine phosphatase PIR:S53931. (212 aa) |
| | Ta0942 | glutamyl-tRNA synthetase related protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (550 aa) |
| | Ta0952 | Probable malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (325 aa) |
| | Ta0955 | Probable porphobilinogen synthase; Strong similarity to known protein: DELTA-AMINOLEVULINIC ACID DEHYDRATASE (EC 4.2.1.24) (PORPHOBILINOGENSYNTHASE) (ALAD) (ALADH) - Escherichia coli; SWISSPROT:HEM2_ECOLI; Belongs to the ALAD family. (320 aa) |
| | Ta0977 | Methionine synthase (cobalamin-independent) related protein; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown (By similarity). (343 aa) |
| | Ta0978 | Conserved hypothetical protein; Similarity to unknown protein: tetrahydropteroyltriglutamate methyltransferase PAB2361 - Pyrococcus abyssi (strain Orsay); PIR:B75138. (290 aa) |
| | Ta0987 | Similarity to known protein: Giardia intestinalis arginine deiminase gene, complete cds; TREMBL:GI49236_1. (418 aa) |
| | Ta1001 | Probable fumarate reductase (frdA); Strong similarity to known protein: S.acidocaldarius sdhA, sdhB, sdhC and sdhD genes; TREMBL:SASDHABCD_2. (567 aa) |
| | Ta1002 | Probable fumarate reductase, subunit B; Strong similarity to known protein: FUMARATE REDUCTASE IRON-SULFUR PROTEIN (EC 1.3.99.1) - Proteus vulgaris; SWISSPROT:FRDB_PROVU. (240 aa) |
| | Ta1003 | Known protein: probable cytochrome b, diheme - Thermoplasma acidophilum; PIR:S34620. (130 aa) |
| | Ta1004 | Succinate dehydrogenase, subunit D; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (123 aa) |
| | Ta1014 | Probable GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (186 aa) |
| | Ta1044 | Conserved hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer [...] (84 aa) |
| | Ta1066 | Phosphoribosylformylglycinamidine synthase related protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thoug [...] (759 aa) |
| | Ta1074 | Similarity to known protein: glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Xanthomonas campestris pv. campestris; PIR:A49906. (247 aa) |
| | Ta1075 | Probable 3-phosphoglycerate kinase; Strong similarity to known protein: phosphoglycerate kinase (EC 2.7.2.3) [validated] - Methanothermus fervidus (fragment); PIR:PN0008. (408 aa) |
| | Ta1100 | Probable phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (180 aa) |
| | Ta1103 | Strong similarity to known protein: glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Methanothermus fervidus; PIR:JT0286. (338 aa) |
| | Ta1107 | Phosphoribosylaminoimidazole carboxylase related protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (360 aa) |
| | Ta1113 | Probable nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (148 aa) |
| | Ta1139 | Aut related protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (142 aa) |
| | Ta1179 | Similarity to known protein: HOMOSERINE DEHYDROGENASE (EC 1.1.1.3) (HDH) - Bacillus subtilis; SWISSPROT:DHOM_BACSU. (324 aa) |
| | Ta1193 | Similarity to known protein: AROMATIC AMINO ACID AMINOTRANSFERASE II (EC 2.6.1.-) - Saccharomyces cerevisiae (Baker's yeast); SWISSPROT:ARO9_YEAST. (402 aa) |
| | Ta1198 | Similarity to known protein: 4-hydroxybenzoate octaprenyltransferase (EC 2.5.1.-) - Escherichia coli; PIR:JC2316Function: ubiquinone biosynthesis. (286 aa) |
| | Ta1199 | Similarity to known protein: Clostridium hydroxybenzoicum 4-hydroxybenzoate decarboxylase (ohb1) gene, complete cds; TREMBLNEW:AF128880_1Function: Phenylalanine metabolism. (480 aa) |
| | Ta1209 | Trehalose-6-phosphate phosphatase related protein; Removes the phosphate from trehalose 6-phosphate (Tre6P) to produce free trehalose. Also catalyzes the dephosphorylation of para- nitrophenyl phosphate (pNPP), but with lesser efficiency (in vitro). (229 aa) |
| | Ta1210 | Similarity to known protein: alpha, alpha-trehalose-phosphate synthase (UDP-forming) (EC 2.4.1.15) - Escherichia coli; PIR:I83402. (441 aa) |
| | Ta1242 | Probable amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (474 aa) |
| | Ta1247 | Probable adenylate kinase; Strong similarity to known protein: ADENYLATE KINASE (EC 2.7.4.3) (ATP-AMP TRANSPHOSPHORYLASE) - Methanococcus igneus; SWISSPROT:KAD_METIG; Belongs to the archaeal adenylate kinase family. (183 aa) |
| | Ta1305 | Hypothetical protein; Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, only present in extreme acidophiles of the Thermoplasmatales order, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. (318 aa) |
| | Ta1313 | Geranylgeranyl pyrophosphate synthase related protein; Similarity to known protein: probable idsA2 protein - Mycobacterium tuberculosis (strain H37RV); PIR:G70935; Belongs to the FPP/GGPP synthase family. (354 aa) |
| | Ta1315 | Probable ribulose-5-phosphate 3-epimerase; Strong similarity to known protein: RIBULOSE-PHOSPHATE 3-EPIMERASE PRECURSOR (EC 5.1.3.1) (PENTOSE-5-PHOSPHATE 3-EPIMERASE) (PPE) (RPE) (R5P3E) - Oryza sativa (Rice); SWISSPROT:RPE_ORYSA. (211 aa) |
| | Ta1318 | Phosphoribosylformylglycinamidine synthase I related protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is tho [...] (289 aa) |
| | Ta1330 | Probable ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (297 aa) |
| | Ta1331 | Probable succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa) |
| | Ta1332 | Probable succinyl-CoA synthetase, beta subunit; Strong similarity to known protein: succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) beta chain [validated] - Thermus aquaticus; PIR:S15950. (376 aa) |
| | Ta1347 | Hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. (214 aa) |
| | Ta1357 | Glycine dehydrogenase (decarboxylating) related protein, subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (472 aa) |
| | Ta1358 | Glycine dehydrogenase (decarboxylating) related protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (433 aa) |
| | Ta1366 | Probable glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (124 aa) |
| | Ta1419 | Conserved hypothetical protein; Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency; Belongs to the PGI/PMI family. (310 aa) |
| | Ta1428 | Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (375 aa) |
| | Ta1435 | Similarity to known protein: dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Bacillus subtilis; PIR:E36718. (436 aa) |
| | Ta1436 | Probable lipoamide acyltransferase; Strong similarity to known protein: Myxococcus xanthus lipoic acid synthetase precursor, lipoamideacyltransferase, and lipoate-protein ligase B genes, complete cds; andunknown genes; TREMBL:AF153678_2. (400 aa) |
| | Ta1437 | Strong similarity to known protein: 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4) chain E1-beta - Pseudomonas putida; PIR:DEPSEB. (319 aa) |
| | Ta1438 | Strong similarity to known protein: 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4) alpha chain precursor - human; PIR:DEHUXAORF_prediction: The N-terminus of this protein is short by 60aa compared to other proteins, sequence analysis clearly rules out an elongated N-terminus. (337 aa) |
| | Ta1455 | Conserved hypothetical protein; Strong similarity to unknown protein: acyl carrier protein synthase - Methanococcus jannaschii; PIR:A64493; Belongs to the thiolase-like superfamily. UPF0219 family. (351 aa) |
| | Ta1456 | Probable 3-ketoacyl-CoA thiolase; Similarity to known protein: probable nonspecific lipid-transfer protein - Pyrococcus horikoshii; PIR:E71113Function: Fatty acid biosynthesis (path 2), Fatty acid metabolism, Valine, leucine and isoleucine degradation, Phenylalanine metabolism. (387 aa) |
| | Ta1486 | Similarity to known protein: mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) - yeast (Saccharomyces cerevisiae); PIR:S67590Function: Fructose and mannose metabolism. (359 aa) |
| | Ta1508 | Probable SA protein; Strong similarity to known protein: Mus musculus SA mRNA, complete cds; TREMBL:AB022340_1. (528 aa) |
| | Ta1509 | Probable glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (436 aa) |
