(52 nodes) Mixed, incl. Response to virus, and Quorum sensing network (Thermoplasma volcanium)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TVG0110650	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (86 aa)
	TVG0110910	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (322 aa)
	TVG0111880	Hypothetical protein. (244 aa)
	TVG0112611	TVG0112611 protein. (385 aa)
	TVG0113769	TVG0113769 protein. (296 aa)
	TVG0114661	Hypothetical protein. (229 aa)
	TVG0115343	Hypothetical protein. (160 aa)
	TVG0115828	Hypothetical protein. (775 aa)
	TVG0118145	Hypothetical protein. (237 aa)
	TVG0120325	Hypothetical protein. (406 aa)
	TVG0209075	TVG0209075 protein. (112 aa)
	TVG0210789	TVG0210789 protein. (519 aa)
	TVG0211687	ABC transport system permease protein P1P2A. (296 aa)
	TVG0212495	ABC transport system permease protein P1P2A. (268 aa)
	TVG0213590	ABC transport system ATP-binding protein P1P2A. (353 aa)
	TVG0288250	Hypothetical protein. (409 aa)
	TVG0290017	TVG0290017 protein. (123 aa)
	TVG0461540	Hypothetical protein. (240 aa)
	TVG0463720	Hypothetical protein. (402 aa)
	TVG0464013	TVG0464013 protein. (95 aa)
	TVG0500467	ABC transport system ATP-binding protein A1A2. (306 aa)
	TVG0501242	ABC transport system ATP-binding protein A1A2. (257 aa)
	TVG0696003	TVG0696003 protein. (647 aa)
	TVG0696684	TVG0696684 protein. (186 aa)
	TVG0696965	TVG0696965 protein. (68 aa)
	TVG0697170	Transposase. (67 aa)
	TVG0874790	Hypothetical protein. (150 aa)
	TVG0875243	Anaerobic glycerol-3-phosphate dehydrogenase subunit alpha. (414 aa)
	TVG0876539	Hypothetical protein. (161 aa)
	TVG0877087	Hypothetical protein. (434 aa)
	TVG0878378	Transposase. (134 aa)
	TVG0878825	TVG0878825 protein. (66 aa)
	TVG1191381	TVG1191381 protein. (164 aa)
	TVG1192129	Glycerol kinase. (498 aa)
	TVG1194688	TVG1194688 protein. (307 aa)
	TVG1196198	ABC transport system protein SP1P2A. (440 aa)
	TVG1197131	ABC transport system permease protein SP1P2A. (309 aa)
	TVG1198021	ABC transport system permease protein SP1P2A. (295 aa)
	TVG1199143	ABC transport system ATP-binding protein SP1P2A. (371 aa)
	TVG1201040	TVG1201040 protein. (643 aa)
	TVG1202803	TVG1202803 protein. (585 aa)
	TVG1202787	Hypothetical protein. (352 aa)
	TVG1395987	TVG1395987 protein. (111 aa)
	TVG1396300	ABC transport system ATP-binding protein P1P2A1A2. (477 aa)
	TVG1397733	ABC transport system ATP-binding protein P1P2A1A2. (522 aa)
	TVG1399304	ABC transport system permease protein P1P2A1A2. (319 aa)
	TVG1400273	ABC transport system permease protein P1P2A1A2. (363 aa)
	TVG1401500	Hypothetical protein. (963 aa)
	TVG1405254	TVG1405254 protein. (186 aa)
	TVG1477736	Hypothetical protein. (222 aa)
	TVG1479283	Hypothetical protein. (399 aa)
	TVG1502957	TVG1502957 protein. (928 aa)

Your Current Organism:

Thermoplasma volcanium

NCBI taxonomy Id: 273116
Other names: T. volcanium GSS1, Thermoplasma volcanium GSS1, Thermoplasma volcanium str. GSS1, Thermoplasma volcanium strain GSS1

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TVG0110650	TVG0110910	gene:9380872	gene:9380873	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.999
TVG0110650	TVG0111880	gene:9380872	gene:9380874	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.793
TVG0110650	TVG0112611	gene:9380872	gene:9380875	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	TVG0112611 protein.	0.863
TVG0110650	TVG0113769	gene:9380872	gene:9380876	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	TVG0113769 protein.	0.863
TVG0110650	TVG0114661	gene:9380872	gene:9380877	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.909
TVG0110650	TVG0115343	gene:9380872	gene:9380878	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.871
TVG0110650	TVG0115828	gene:9380872	gene:9380879	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.931
TVG0110650	TVG0118145	gene:9380872	gene:9380880	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.918
TVG0110650	TVG0120325	gene:9380872	gene:9380881	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.607
TVG0110910	TVG0110650	gene:9380873	gene:9380872	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.999
TVG0110910	TVG0111880	gene:9380873	gene:9380874	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.782
TVG0110910	TVG0112611	gene:9380873	gene:9380875	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	TVG0112611 protein.	0.837
TVG0110910	TVG0113769	gene:9380873	gene:9380876	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	TVG0113769 protein.	0.837
TVG0110910	TVG0114661	gene:9380873	gene:9380877	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.915
TVG0110910	TVG0115343	gene:9380873	gene:9380878	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.837
TVG0110910	TVG0115828	gene:9380873	gene:9380879	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.932
TVG0110910	TVG0118145	gene:9380873	gene:9380880	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.898
TVG0110910	TVG0120325	gene:9380873	gene:9380881	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein.	0.505
TVG0111880	TVG0110650	gene:9380874	gene:9380872	Hypothetical protein.	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.793
TVG0111880	TVG0110910	gene:9380874	gene:9380873	Hypothetical protein.	Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.782