STRINGSTRING
TVG0015475 TVG0015475 TVG0019502 TVG0019502 TVG0025258 TVG0025258 TVG0048225 TVG0048225 TVG0060439 TVG0060439 TVG0067028 TVG0067028 TVG0067506 TVG0067506 TVG0075057 TVG0075057 TVG0102621 TVG0102621 TVG0103933 TVG0103933 TVG0105141 TVG0105141 TVG0106097 TVG0106097 TVG0141026 TVG0141026 TVG0142182 TVG0142182 TVG0142586 TVG0142586 TVG0179275 TVG0179275 TVG0183359 TVG0183359 TVG0196114 TVG0196114 TVG0201218 TVG0201218 TVG0201915 TVG0201915 TVG0204657 TVG0204657 TVG0218327 TVG0218327 TVG0226058 TVG0226058 TVG0252956 TVG0252956 TVG0270675 TVG0270675 TVG0278338 TVG0278338 TVG0284189 TVG0284189 TVG0285047 TVG0285047 TVG0294815 TVG0294815 TVG0303364 TVG0303364 TVG0309943 TVG0309943 TVG0311358 TVG0311358 TVG0357199 TVG0357199 TVG0361650 TVG0361650 TVG0362515 TVG0362515 TVG0385916 TVG0385916 TVG0387048 TVG0387048 TVG0388541 TVG0388541 TVG0388568 TVG0388568 TVG0444310 TVG0444310 TVG0502242 TVG0502242 TVG0521991 TVG0521991 TVG0643747 TVG0643747 TVG0647983 TVG0647983 TVG0660430 TVG0660430 TVG0661085 TVG0661085 TVG0662032 TVG0662032 TVG0663048 TVG0663048 TVG0664080 TVG0664080 TVG0665344 TVG0665344 TVG0691226 TVG0691226 TVG0723257 TVG0723257 TVG0742429 TVG0742429 TVG0744794 TVG0744794 TVG0760262 TVG0760262 TVG0760633 TVG0760633 TVG0761062 TVG0761062 TVG0761794 TVG0761794 TVG0773051 TVG0773051 TVG0774569 TVG0774569 TVG0785282 TVG0785282 TVG0797109 TVG0797109 TVG0808604 TVG0808604 TVG0861800 TVG0861800 TVG0862758 TVG0862758 TVG0869690 TVG0869690 TVG0870514 TVG0870514 TVG0870807 TVG0870807 TVG0871982 TVG0871982 TVG0872869 TVG0872869 TVG0881751 TVG0881751 TVG0882664 TVG0882664 TVG0939251 TVG0939251 TVG0959514 TVG0959514 TVG0968612 TVG0968612 TVG0993131 TVG0993131 TVG0995648 TVG0995648 TVG1000457 TVG1000457 TVG1010750 TVG1010750 TVG1029756 TVG1029756 TVG1033459 TVG1033459 TVG1043834 TVG1043834 TVG1044624 TVG1044624 TVG1073292 TVG1073292 TVG1076108 TVG1076108 TVG1076124 TVG1076124 TVG1110903 TVG1110903 TVG1148597 TVG1148597 TVG1151701 TVG1151701 TVG1170798 TVG1170798 TVG1206092 TVG1206092 TVG1211894 TVG1211894 TVG1213330 TVG1213330 TVG1231223 TVG1231223 TVG1250055 TVG1250055 TVG1257432 TVG1257432 TVG1289977 TVG1289977 TVG1294312 TVG1294312 TVG1304136 TVG1304136 TVG1322048 TVG1322048 TVG1322512 TVG1322512 TVG1323003 TVG1323003 TVG1324343 TVG1324343 TVG1328971 TVG1328971 TVG1331499 TVG1331499 TVG1333406 TVG1333406 TVG1342946 TVG1342946 TVG1343229 TVG1343229 TVG1344033 TVG1344033 TVG1345079 TVG1345079 TVG1347387 TVG1347387 TVG1348694 TVG1348694 TVG1350001 TVG1350001 TVG1351870 TVG1351870 TVG1365594 TVG1365594 TVG1370641 TVG1370641 TVG1371752 TVG1371752 TVG1372228 TVG1372228 TVG1372758 TVG1372758 TVG1373162 TVG1373162 TVG1375308 TVG1375308 TVG1375310 TVG1375310 TVG1405258 TVG1405258 TVG1406112 TVG1406112 TVG1415417 TVG1415417 TVG1454962 TVG1454962 TVG1455840 TVG1455840 TVG1458424 TVG1458424 TVG1514630 TVG1514630 TVG1520544 TVG1520544 TVG1526682 TVG1526682 TVG1571797 TVG1571797
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TVG0015475enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (251 aa)
TVG0019502Acylphosphatase. (90 aa)
TVG00252584-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
TVG0048225Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa)
TVG0060439Aminomethyltransferase. (359 aa)
TVG0067028Hypothetical protein. (155 aa)
TVG0067506Lipid transfer protein. (390 aa)
TVG0075057D-mannonate hydrolase. (333 aa)
TVG0102621Pyruvate dehydrogenase E3 / dihydrolipoamide dehydrogenase. (436 aa)
TVG0103933Pyruvate dehydrogenase E2 / dihydrolipoamide acetyltransferase. (400 aa)
TVG0105141Pyruvate dehydrogenase E1 /pyruvate decarboxylase. (319 aa)
TVG01060972-oxoisovalerate dehydrogenase alpha subunit. (337 aa)
TVG0141026Acyl carrier protein synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (351 aa)
TVG0142182Lipid transfer protein. (387 aa)
TVG0142586Hypothetical protein in ferredoxin oxidoreductase operon. (135 aa)
TVG01792752-dehydro-3-deoxyphosphogalactonate aldolase. (398 aa)
TVG0183359Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (249 aa)
TVG0196114Aconitate hydratase. (881 aa)
TVG0201218Isocitrate dehydrogenase. (405 aa)
TVG0201915Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily. (286 aa)
TVG0204657Phosphoenolpyrvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (589 aa)
TVG0218327Alpha-mannosidase. (1013 aa)
TVG0226058Cyclomaltodextrinase [amylase]. (619 aa)
TVG0252956Citrate synthase. (386 aa)
TVG0270675Phosphoglycerate mutase. (201 aa)
TVG0278338Ribulose-5-phosphate 3-epimerase. (211 aa)
TVG0284189succinyl-CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (285 aa)
TVG0285047succinyl-CoA synthetase beta subunit. (384 aa)
TVG0294815Hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate. (224 aa)
TVG0303364Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (122 aa)
TVG0309943Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (434 aa)
TVG0311358Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (472 aa)
TVG03571993-hydroxbutyryl-CoA dehydratase. (228 aa)
TVG0361650Carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (272 aa)
TVG0362515MMGE/PRPD family protein. (443 aa)
TVG0385916Hypothetical protein. (139 aa)
TVG0387048NADH dependent alcohol dehydrogenase. (373 aa)
TVG0388541Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (498 aa)
TVG03885688-amino-7-oxononanoate synthetase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (396 aa)
TVG0444310Glyceraldehyde-3-phosphate dehydrogenase. (338 aa)
TVG0502242Hypothetical protein. (226 aa)
TVG0521991Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (408 aa)
TVG0643747acetyl-CoA acetyltransferase. (388 aa)
TVG06479831-pyrroline-5-carboxylate dehydrogenase. (515 aa)
TVG0660430Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (223 aa)
TVG0661085Transketolase. (316 aa)
TVG0662032Transketolase. (273 aa)
TVG0663048Dihydrodipicolinate synthase. (288 aa)
TVG0664080acyl-CoA dehydrogenase. (420 aa)
TVG0665344Medium-chain acyl-CoA ligase. (518 aa)
TVG0691226Beta-glycosidase; Belongs to the glycosyl hydrolase 1 family. (481 aa)
TVG0723257Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (241 aa)
TVG0742429Glucose kinase. (315 aa)
TVG0744794Phosphoglycerate mutase. (189 aa)
TVG0760262Hypothetical protein. (123 aa)
TVG0760633Succinate dehydrogenase cytochrome b subunit. (140 aa)
TVG0761062Succinate dehydrogenase iron sulfur subunit. (240 aa)
TVG0761794Succinate dehydrogenase flavoprotein. (567 aa)
TVG0773051Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (435 aa)
TVG0774569Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (416 aa)
TVG0785282Malate oxidoreductase. (451 aa)
TVG0797109Glycerate kinase. (420 aa)
TVG0808604Aldehyde-ferredoxin oxidoreductase [AOR]. (603 aa)
TVG0861800Hypothetical protein. (343 aa)
TVG08627583-hydroxyacyl-CoA dehydrogenase. (294 aa)
TVG0869690Phosphoglycerate mutase. (206 aa)
TVG0870514Pyruvate ferredoxin oxidoreductasse [POR] gamma subunit. (185 aa)
TVG0870807Pyruvate ferredoxin oxidoreductasse [POR] delta subunit. (95 aa)
TVG0871982Pyruvate ferredoxin oxidoreductasse [POR] alpha subunit. (392 aa)
TVG0872869Pyruvate ferredoxin oxidoreductasse [POR] beta subunit. (295 aa)
TVG08817512-ketovalerate ferredoxin oxidoreductase [VOR] alpha subunit. (629 aa)
TVG08826642-ketovalerate ferredoxin oxidoreductase [VOR] beta subunit. (309 aa)
TVG0939251Gamma-glutamyltransferase. (505 aa)
TVG09595142-isopropylmalate/homocitrate synthetase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (344 aa)
TVG0968612enoyl-CoA hydratase. (249 aa)
TVG0993131Phosphoglycolate phosphatase. (207 aa)
TVG0995648Alcohol dehydrogenase [ADH]. (335 aa)
TVG1000457TVG1000457 protein. (270 aa)
TVG1010750D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (303 aa)
TVG1029756Pyruvate orthophosphate dikinase. (886 aa)
TVG1033459Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa)
TVG1043834TVG1043834 protein. (87 aa)
TVG1044624Lipoate-protein ligase. (262 aa)
TVG1073292Glucose 1-dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway. (361 aa)
TVG1076108Pyruvate kinase; Belongs to the pyruvate kinase family. (541 aa)
TVG1076124Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (493 aa)
TVG1110903Aldehyde dehydrogenase. (514 aa)
TVG11485973-hydroxybutyryl-coa dehydrogenase. (314 aa)
TVG1151701Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (325 aa)
TVG1170798acyl-CoA dehydrogenase. (384 aa)
TVG1206092acetyl-CoA synthetase. (650 aa)
TVG1211894Sulfide dehydrogenase alpha subunit / glutamate synthase small chain. (484 aa)
TVG1213330Phosphonopyruvate decarboxylase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (406 aa)
TVG1231223acyl-CoA dehydrogenase. (397 aa)
TVG12500552-dehydro-3-deoxyphosphogalactonate aldolase. (388 aa)
TVG1257432D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (304 aa)
TVG1289977Dihydrodipicolinate synthase. (289 aa)
TVG1294312Succinyl CoA synthetase alpha subunit. (693 aa)
TVG1304136Aldehyde ferredoxin oxidoreductase [AOR]. (624 aa)
TVG1322048Mutator protein [MutT]. (154 aa)
TVG1322512Hypothetical protein. (164 aa)
TVG1323003Nonspecific lipid-transfer protein. (420 aa)
TVG1324343Hypothetical protein. (214 aa)
TVG1328971acetyl-CoA synthetase. (641 aa)
TVG1331499acetyl-CoA synthetase. (619 aa)
TVG1333406isovaleryl-CoA dehydrogenase precursor. (382 aa)
TVG1342946Electron transfer flavoprotein. (428 aa)
TVG1343229Ferredoxin. (90 aa)
TVG1344033Electron transfer flavoprotein beta-subunit. (265 aa)
TVG1345079Electron transfer flavoprotein alpha-subunit. (349 aa)
TVG1347387Aldehyde dehydrogenase. (436 aa)
TVG1348694Alcohol dehydrogenase [ADH]. (433 aa)
TVG1350001Hypothetical protein. (271 aa)
TVG1351870Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (223 aa)
TVG1365594Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family. (791 aa)
TVG1370641acetyl-CoA acetyltransferase. (396 aa)
TVG1371752acyl-CoA dehydrogenase. (369 aa)
TVG1372228TVG1372228 protein. (159 aa)
TVG1372758TVG1372758 protein. (169 aa)
TVG1373162Hypothetical protein; Belongs to the thioesterase PaaI family. (133 aa)
TVG1375308Medium-chain acyl-CoA ligase. (529 aa)
TVG13753103-hydroxyacyl-CoA dehydrogenase. (659 aa)
TVG1405258Ferredoxin oxidoreductase [KOR] beta subunit. (285 aa)
TVG1406112Ferredoxin oxidoreductase [KOR] alpha subunit. (585 aa)
TVG1415417acyl-CoA dehydrogenase. (376 aa)
TVG1454962Electron transfer flavoprotein alpha-subunit. (293 aa)
TVG1455840Electron transfer flavoprotein beta-subunit. (260 aa)
TVG1458424Pyruvate dehydrogenase E3 / dihydrolipoamide dehydrogenase. (450 aa)
TVG1514630Hypothetical protein; Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency. Belongs to the PGI/PMI family. (304 aa)
TVG1520544Hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (376 aa)
TVG1526682Fuculose-1-phosphate aldolase. (221 aa)
TVG1571797Glutamine synthetase. (462 aa)
Your Current Organism:
Thermoplasma volcanium
NCBI taxonomy Id: 273116
Other names: T. volcanium GSS1, Thermoplasma volcanium GSS1, Thermoplasma volcanium str. GSS1, Thermoplasma volcanium strain GSS1
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