(51 nodes) Membrane protein complex network (Thermoplasma volcanium)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TVG0050546	H+-transporting ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (204 aa)
	TVG0388568	8-amino-7-oxononanoate synthetase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (396 aa)
	TVG0364778	Hypothetical protein. (104 aa)
	TVG0363970	Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. (272 aa)
	TVG0346559	Hypothetical protein. (225 aa)
	TVG0331810	Hypothetical protein. (135 aa)
	TVG0262802	Hypothetical protein. (386 aa)
	TVG0230905	Signal sequence peptidase. (251 aa)
	TVG0213590	ABC transport system ATP-binding protein P1P2A. (353 aa)
	TVG0212495	ABC transport system permease protein P1P2A. (268 aa)
	TVG0211687	ABC transport system permease protein P1P2A. (296 aa)
	TVG0097142	Hypothetical protein. (592 aa)
	TVG0058686	H+-transporting ATP synthase subunit I; Belongs to the V-ATPase 116 kDa subunit family. (643 aa)
	TVG0056752	Hypothetical protein. (111 aa)
	TVG0056269	H+-transporting ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (209 aa)
	TVG0055637	H+-transporting ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (460 aa)
	TVG0054274	H+-transporting ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit; Belongs to the ATPase alpha/beta chains family. (776 aa)
	TVG0051618	V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (356 aa)
	TVG0455305	Hypothetical protein. (295 aa)
	TVG0049983	H+-transporting ATP synthase subunit K. (75 aa)
	TVG0045165	TVG0045165 protein. (169 aa)
	TVG0007048	Hypothetical protein. (135 aa)
	TVG0720869	Transposase. (123 aa)
	TVG0721670	Hypothetical protein. (130 aa)
	TVG0760262	Hypothetical protein. (123 aa)
	TVG0760633	Succinate dehydrogenase cytochrome b subunit. (140 aa)
	TVG0761062	Succinate dehydrogenase iron sulfur subunit. (240 aa)
	TVG0761794	Succinate dehydrogenase flavoprotein. (567 aa)
	TVG0780828	Hypothetical protein. (416 aa)
	TVG0786138	Hypothetical protein. (249 aa)
	TVG0843689	DNA helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (674 aa)
	TVG0877087	Hypothetical protein. (434 aa)
	TVG0952253	Hypothetical protein. (127 aa)
	TVG0988599	ABC-2 integral membrane protein. (267 aa)
	TVG1001758	Hypothetical protein. (386 aa)
	TVG1164251	NADH dehydrogenase I chain D. (369 aa)
	TVG1165354	NADH dehydrogenase I chain C. (151 aa)
	TVG1184459	TVG1184459 protein. (105 aa)
	TVG1197131	ABC transport system permease protein SP1P2A. (309 aa)
	TVG1198021	ABC transport system permease protein SP1P2A. (295 aa)
	TVG1199143	ABC transport system ATP-binding protein SP1P2A. (371 aa)
	TVG1244656	Hypothetical protein. (393 aa)
	TVG1285178	Hypothetical protein. (416 aa)
	TVG1440155	ABC-2 integral membrane protein. (254 aa)
	TVG1506668	ABC transport system ATP-binding protein. (247 aa)
	TVG0537100	ABC transport system ATP-binding protein PA. (294 aa)
	TVG0645074	Hypothetical protein. (417 aa)
	TVG0523258	Signal recognition particle protein dpa; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (287 aa)
	TVG0489908	K+-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (209 aa)
	TVG0489285	K+-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (668 aa)
	TVG0487282	K+-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (585 aa)

Your Current Organism:

Thermoplasma volcanium

NCBI taxonomy Id: 273116
Other names: T. volcanium GSS1, Thermoplasma volcanium GSS1, Thermoplasma volcanium str. GSS1, Thermoplasma volcanium strain GSS1

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TVG0045165	TVG0262802	gene:9380807	gene:9381020	TVG0045165 protein.	Hypothetical protein.	0.469
TVG0045165	TVG0455305	gene:9380807	gene:9381248	TVG0045165 protein.	Hypothetical protein.	0.708
TVG0045165	TVG0786138	gene:9380807	gene:9381573	TVG0045165 protein.	Hypothetical protein.	0.513
TVG0045165	TVG0952253	gene:9380807	gene:9381715	TVG0045165 protein.	Hypothetical protein.	0.604
TVG0045165	TVG1001758	gene:9380807	gene:9381773	TVG0045165 protein.	Hypothetical protein.	0.494
TVG0045165	TVG1244656	gene:9380807	gene:9382016	TVG0045165 protein.	Hypothetical protein.	0.514
TVG0049983	TVG0050546	gene:9380812	gene:9380813	H+-transporting ATP synthase subunit K.	H+-transporting ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
TVG0049983	TVG0051618	gene:9380812	gene:9380814	H+-transporting ATP synthase subunit K.	V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
TVG0049983	TVG0054274	gene:9380812	gene:9380816	H+-transporting ATP synthase subunit K.	H+-transporting ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit; Belongs to the ATPase alpha/beta chains family.	0.999
TVG0049983	TVG0055637	gene:9380812	gene:9380817	H+-transporting ATP synthase subunit K.	H+-transporting ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	0.999
TVG0049983	TVG0056269	gene:9380812	gene:9380818	H+-transporting ATP synthase subunit K.	H+-transporting ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
TVG0049983	TVG0056752	gene:9380812	gene:9380819	H+-transporting ATP synthase subunit K.	Hypothetical protein.	0.985
TVG0049983	TVG0058686	gene:9380812	gene:9380820	H+-transporting ATP synthase subunit K.	H+-transporting ATP synthase subunit I; Belongs to the V-ATPase 116 kDa subunit family.	0.999
TVG0049983	TVG0230905	gene:9380812	gene:9380993	H+-transporting ATP synthase subunit K.	Signal sequence peptidase.	0.626
TVG0049983	TVG0761062	gene:9380812	gene:9381547	H+-transporting ATP synthase subunit K.	Succinate dehydrogenase iron sulfur subunit.	0.506
TVG0049983	TVG0761794	gene:9380812	gene:9381548	H+-transporting ATP synthase subunit K.	Succinate dehydrogenase flavoprotein.	0.519
TVG0049983	TVG1164251	gene:9380812	gene:9381936	H+-transporting ATP synthase subunit K.	NADH dehydrogenase I chain D.	0.719
TVG0049983	TVG1165354	gene:9380812	gene:9381937	H+-transporting ATP synthase subunit K.	NADH dehydrogenase I chain C.	0.701
TVG0050546	TVG0049983	gene:9380813	gene:9380812	H+-transporting ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.	H+-transporting ATP synthase subunit K.	0.999
TVG0050546	TVG0051618	gene:9380813	gene:9380814	H+-transporting ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.	V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999