(9 nodes) (2018) Site-directed mutagenesis of Campylobacter concisus respiratory genes provides insight into the pathogens growth requirements. network (Wolinella succinogenes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TATC	TRANSLOCASE PROTEIN TATC HOMOLOG; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (241 aa)
	fdhA-2	THIOSULFATE REDUCTASE .-.-; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (801 aa)
	CYTA	CYTA PROTEIN PRECURSOR. (371 aa)
	NAPA	PERIPLASMIC NITRATE REDUCTASE; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (947 aa)
	NRFA	CYTOCHROME C NITRITE REDUCTASE; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine, and even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH. (507 aa)
	TTRA	TTRA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1010 aa)
	NOSZ-2	NOSZ PROTEIN. (470 aa)
	NOSZ	NITROUS OXIDE REDUCTASE CATALYTIC SUBUNIT. (410 aa)
	csrA	Hypothetical protein; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (76 aa)

Your Current Organism:

Wolinella succinogenes

NCBI taxonomy Id: 273121
Other names: W. succinogenes DSM 1740, Wolinella succinogenes DSM 1740

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYTA	TTRA	WS0009	WS0938	CYTA PROTEIN PRECURSOR.	TTRA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.719
CYTA	csrA	WS0009	WS0879	CYTA PROTEIN PRECURSOR.	Hypothetical protein; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.	0.511
CYTA	fdhA-2	WS0009	WS0709	CYTA PROTEIN PRECURSOR.	THIOSULFATE REDUCTASE .-.-; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.678
NAPA	NOSZ	WS1178	WS0914	PERIPLASMIC NITRATE REDUCTASE; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.	NITROUS OXIDE REDUCTASE CATALYTIC SUBUNIT.	0.738
NAPA	NOSZ-2	WS1178	WS0916	PERIPLASMIC NITRATE REDUCTASE; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.	NOSZ PROTEIN.	0.740
NAPA	NRFA	WS1178	WS0969	PERIPLASMIC NITRATE REDUCTASE; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.	CYTOCHROME C NITRITE REDUCTASE; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine, and even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH.	0.967
NAPA	TTRA	WS1178	WS0938	PERIPLASMIC NITRATE REDUCTASE; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.	TTRA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.438
NOSZ	NAPA	WS0914	WS1178	NITROUS OXIDE REDUCTASE CATALYTIC SUBUNIT.	PERIPLASMIC NITRATE REDUCTASE; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.	0.738
NOSZ	NOSZ-2	WS0914	WS0916	NITROUS OXIDE REDUCTASE CATALYTIC SUBUNIT.	NOSZ PROTEIN.	0.997
NOSZ	NRFA	WS0914	WS0969	NITROUS OXIDE REDUCTASE CATALYTIC SUBUNIT.	CYTOCHROME C NITRITE REDUCTASE; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine, and even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH.	0.707
NOSZ	csrA	WS0914	WS0879	NITROUS OXIDE REDUCTASE CATALYTIC SUBUNIT.	Hypothetical protein; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.	0.435
NOSZ-2	NAPA	WS0916	WS1178	NOSZ PROTEIN.	PERIPLASMIC NITRATE REDUCTASE; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.	0.740
NOSZ-2	NOSZ	WS0916	WS0914	NOSZ PROTEIN.	NITROUS OXIDE REDUCTASE CATALYTIC SUBUNIT.	0.997
NOSZ-2	NRFA	WS0916	WS0969	NOSZ PROTEIN.	CYTOCHROME C NITRITE REDUCTASE; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine, and even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH.	0.705
NRFA	NAPA	WS0969	WS1178	CYTOCHROME C NITRITE REDUCTASE; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine, and even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH.	PERIPLASMIC NITRATE REDUCTASE; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.	0.967
NRFA	NOSZ	WS0969	WS0914	CYTOCHROME C NITRITE REDUCTASE; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine, and even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH.	NITROUS OXIDE REDUCTASE CATALYTIC SUBUNIT.	0.707
NRFA	NOSZ-2	WS0969	WS0916	CYTOCHROME C NITRITE REDUCTASE; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine, and even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH.	NOSZ PROTEIN.	0.705
TTRA	CYTA	WS0938	WS0009	TTRA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	CYTA PROTEIN PRECURSOR.	0.719
TTRA	NAPA	WS0938	WS1178	TTRA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	PERIPLASMIC NITRATE REDUCTASE; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.	0.438
TTRA	fdhA-2	WS0938	WS0709	TTRA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	THIOSULFATE REDUCTASE .-.-; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.927