STRINGSTRING
patI patI patK patK patH patH PEX2_095640 PEX2_095640 PEX2_085810 PEX2_085810 PEX2_016340 PEX2_016340 PEX2_105670 PEX2_105670 PEX2_074930 PEX2_074930 PEX2_074780 PEX2_074780 PEX2_047780 PEX2_047780 PEX2_074870 PEX2_074870 PEX2_100330 PEX2_100330 PEX2_065770 PEX2_065770 PEX2_050970 PEX2_050970 PEX2_094360 PEX2_094360 PEX2_016160 PEX2_016160 PEX2_055770 PEX2_055770 PEX2_003130 PEX2_003130 PEX2_011670 PEX2_011670 PEX2_034050 PEX2_034050 PEX2_060220 PEX2_060220 PEX2_039570 PEX2_039570 PEX2_040260 PEX2_040260 PEX2_038830 PEX2_038830 PEX2_000340 PEX2_000340 PEX2_041020 PEX2_041020 PEX2_049410 PEX2_049410 PEX2_083190 PEX2_083190 PEX2_063880 PEX2_063880 PEX2_109010 PEX2_109010 PEX2_064700 PEX2_064700 PEX2_031310 PEX2_031310 PEX2_110410 PEX2_110410 PEX2_031150 PEX2_031150 PEX2_022150 PEX2_022150 PEX2_001880 PEX2_001880 PEX2_005360 PEX2_005360 PEX2_104160 PEX2_104160 cnsG cnsG PEX2_096520 PEX2_096520 PEX2_063700 PEX2_063700 PEX2_094820 PEX2_094820 PEX2_007100 PEX2_007100 PEX2_096410 PEX2_096410 PEX2_024420 PEX2_024420 PEX2_032440 PEX2_032440 PEX2_107280 PEX2_107280 PEX2_109090 PEX2_109090 PEX2_109110 PEX2_109110 PEX2_063780 PEX2_063780 PEX2_099070 PEX2_099070 PEX2_048520 PEX2_048520 PEX2_083900 PEX2_083900 PEX2_064650 PEX2_064650 PEX2_083230 PEX2_083230 PEX2_109180 PEX2_109180 PEX2_110280 PEX2_110280 PEX2_109670 PEX2_109670 PEX2_048510 PEX2_048510 PEX2_083940 PEX2_083940 PEX2_061000 PEX2_061000 PEX2_083520 PEX2_083520 PEX2_062980 PEX2_062980 PEX2_032480 PEX2_032480 PEX2_038500 PEX2_038500 PEX2_008520 PEX2_008520 PEX2_071950 PEX2_071950 PEX2_090270 PEX2_090270 PEX2_025200 PEX2_025200 PEX2_038790 PEX2_038790 PEX2_037910 PEX2_037910 PEX2_032250 PEX2_032250 PEX2_049950 PEX2_049950 PEX2_077440 PEX2_077440 PEX2_079810 PEX2_079810 PEX2_096900 PEX2_096900 PEX2_098660 PEX2_098660 PEX2_080600 PEX2_080600 PEX2_038530 PEX2_038530 PEX2_003600 PEX2_003600 PEX2_098970 PEX2_098970 PEX2_020690 PEX2_020690 PEX2_004760 PEX2_004760 PEX2_070370 PEX2_070370 PEX2_071930 PEX2_071930 PEX2_040870 PEX2_040870 PEX2_021940 PEX2_021940 PEX2_069690 PEX2_069690 PEX2_065660 PEX2_065660 PEX2_031140 PEX2_031140 PEX2_066830 PEX2_066830 PEX2_005170 PEX2_005170 PEX2_069710 PEX2_069710 PEX2_072390 PEX2_072390 PEX2_073770 PEX2_073770 PEX2_092060 PEX2_092060 PEX2_054980 PEX2_054980 cnsI cnsI PEX2_073610 PEX2_073610 PEX2_074810 PEX2_074810 PEX2_034170 PEX2_034170 PEX2_074880 PEX2_074880 cnsC cnsC PEX2_055090 PEX2_055090 PEX2_007860 PEX2_007860 PEX2_001100 PEX2_001100 PEX2_013260 PEX2_013260 PEX2_035600 PEX2_035600 PEX2_020720 PEX2_020720 PEX2_035090 PEX2_035090 PEX2_065490 PEX2_065490 PEX2_022130 PEX2_022130 PEX2_081800 PEX2_081800 PEX2_081820 PEX2_081820 PEX2_087950 PEX2_087950 PEX2_065890 PEX2_065890 PEX2_101620 PEX2_101620 PEX2_091230 PEX2_091230 PEX2_013770 PEX2_013770 PEX2_081810 PEX2_081810 PEX2_016080 PEX2_016080 PEX2_074250 PEX2_074250 PEX2_014390 PEX2_014390 PEX2_047350 PEX2_047350 PEX2_044350 PEX2_044350 PEX2_042520 PEX2_042520 PEX2_012570 PEX2_012570 PEX2_011230 PEX2_011230 PEX2_011680 PEX2_011680 PEX2_046390 PEX2_046390 PEX2_045550 PEX2_045550 PEX2_042280 PEX2_042280 PEX2_100300 PEX2_100300 PEX2_011220 PEX2_011220 PEX2_011770 PEX2_011770 PEX2_011600 PEX2_011600 PEX2_081780 PEX2_081780 PEX2_012060 PEX2_012060 PEX2_012410 PEX2_012410 PEX2_017770 PEX2_017770 PEX2_011110 PEX2_011110 PEX2_077640 PEX2_077640 PEX2_001930 PEX2_001930 PEX2_058730 PEX2_058730 PEX2_097700 PEX2_097700 PEX2_107160 PEX2_107160 PEX2_000770 PEX2_000770 PEX2_022760 PEX2_022760 PEX2_055830 PEX2_055830 PEX2_011850 PEX2_011850 PEX2_011780 PEX2_011780 PEX2_041040 PEX2_041040 PEX2_023390 PEX2_023390 PEX2_103810 PEX2_103810
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
patICytochrome P450 monooxygenase patI; Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units. The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol). These first [...] (526 aa)
patK6-methylcalicylic acide synthase; 6-methylcalicylic acide synthase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units. The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m- cresol (also known as 3-methylphenol). These firs [...] (1776 aa)
patHCytochrome P450 monooxygenase patH; Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units. The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol). These first [...] (524 aa)
PEX2_095640Ribosomal protein L13, eukaryotic/archaeal. (792 aa)
PEX2_085810Transcription factor, fungi. (636 aa)
PEX2_016340AMP-dependent synthetase/ligase. (549 aa)
PEX2_105670AMP-dependent synthetase/ligase. (811 aa)
PEX2_074930Male sterility, NAD-binding. (1064 aa)
PEX2_074780Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (512 aa)
PEX2_047780Cytochrome P450. (704 aa)
PEX2_074870Acyl transferase/acyl hydrolase/lysophospholipase. (2137 aa)
PEX2_100330Chloroperoxidase. (808 aa)
PEX2_065770Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (372 aa)
PEX2_050970Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (502 aa)
PEX2_094360Cytochrome P450; Belongs to the cytochrome P450 family. (554 aa)
PEX2_016160Uncharacterized protein. (339 aa)
PEX2_055770AMP-dependent synthetase/ligase. (1435 aa)
PEX2_003130Cytochrome P450; Belongs to the cytochrome P450 family. (490 aa)
PEX2_011670Transcription factor, fungi. (499 aa)
PEX2_034050Cytochrome P450; Belongs to the cytochrome P450 family. (395 aa)
PEX2_060220Cytochrome P450; Belongs to the cytochrome P450 family. (423 aa)
PEX2_039570Uncharacterized protein. (360 aa)
PEX2_040260Cytochrome P450. (780 aa)
PEX2_038830Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (380 aa)
PEX2_000340Cytochrome P450; Belongs to the cytochrome P450 family. (538 aa)
PEX2_041020Cytochrome P450; Belongs to the cytochrome P450 family. (358 aa)
PEX2_049410Transcription factor, fungi. (595 aa)
PEX2_083190Male sterility, NAD-binding. (2332 aa)
PEX2_063880Cytochrome P450; Belongs to the cytochrome P450 family. (381 aa)
PEX2_109010Acyl transferase/acyl hydrolase/lysophospholipase. (2447 aa)
PEX2_064700AMP-dependent synthetase/ligase. (543 aa)
PEX2_031310Cytochrome P450; Belongs to the cytochrome P450 family. (438 aa)
PEX2_110410AMP-dependent synthetase/ligase. (1348 aa)
PEX2_031150Uncharacterized protein. (174 aa)
PEX2_022150Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (514 aa)
PEX2_001880Cytochrome P450; Belongs to the cytochrome P450 family. (544 aa)
PEX2_005360Carboxymuconolactone decarboxylase. (133 aa)
PEX2_104160AMP-dependent synthetase/ligase. (2108 aa)
cnsGAcyl-CoA ligase cnsG; Acyl-CoA ligase; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals. Communesins are biosynthesized by the coupling of tryptamine and aurantioclavine, two building blocks derived from L-tryptophan. The L- tryptophan decarboxylase cnsB converts L-tryptophan to tryptamine, whereas the tryptophan dimethylallyltransferase cnsF converts L- tryptophan to 4-dimethylallyl tryptophan which is further transformed to aurantioclavine by the aurantioclavine synthase cnsA, probabl [...] (481 aa)
PEX2_096520Cytochrome P450. (550 aa)
PEX2_063700Carrier domain-containing protein. (1009 aa)
PEX2_094820Uncharacterized protein. (577 aa)
PEX2_007100Uncharacterized protein family UPF0390. (104 aa)
PEX2_096410Cytochrome P450. (540 aa)
PEX2_024420Male sterility, NAD-binding. (1038 aa)
PEX2_032440AMP-dependent synthetase/ligase. (7287 aa)
PEX2_107280Cytochrome P450. (509 aa)
PEX2_109090Cytochrome P450. (486 aa)
PEX2_109110AMP-dependent synthetase/ligase. (1557 aa)
PEX2_063780Acyl transferase/acyl hydrolase/lysophospholipase. (1783 aa)
PEX2_099070NAD_binding_4 domain-containing protein. (301 aa)
PEX2_048520Polyketide synthase, KR. (355 aa)
PEX2_083900Male sterility, NAD-binding. (1031 aa)
PEX2_064650Carrier domain-containing protein. (1263 aa)
PEX2_083230Acyl transferase/acyl hydrolase/lysophospholipase. (2645 aa)
PEX2_109180Acyl transferase/acyl hydrolase/lysophospholipase. (2463 aa)
PEX2_110280Uncharacterized protein. (309 aa)
PEX2_109670Acyl transferase/acyl hydrolase/lysophospholipase. (2492 aa)
PEX2_048510Acyl transferase/acyl hydrolase/lysophospholipase. (1128 aa)
PEX2_083940AMP-dependent synthetase/ligase. (3239 aa)
PEX2_061000Uncharacterized protein. (3967 aa)
PEX2_083520Cytochrome P450; Belongs to the cytochrome P450 family. (519 aa)
PEX2_062980AMP-dependent synthetase/ligase. (1569 aa)
PEX2_032480Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (515 aa)
PEX2_038500AMP-binding_C domain-containing protein. (131 aa)
PEX2_008520Cytochrome P450; Belongs to the cytochrome P450 family. (471 aa)
PEX2_071950Cytochrome P450; Belongs to the cytochrome P450 family. (519 aa)
PEX2_090270Cytochrome P450. (373 aa)
PEX2_025200AMP-dependent synthetase/ligase. (2645 aa)
PEX2_038790Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (425 aa)
PEX2_037910Polyketide synthase, KR. (443 aa)
PEX2_032250Male sterility, NAD-binding. (601 aa)
PEX2_049950Male sterility, NAD-binding. (1084 aa)
PEX2_077440Male sterility, NAD-binding. (1276 aa)
PEX2_079810Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (543 aa)
PEX2_096900Uncharacterized protein. (601 aa)
PEX2_098660Cytochrome P450; Belongs to the cytochrome P450 family. (499 aa)
PEX2_080600AMP-dependent synthetase/ligase. (1057 aa)
PEX2_038530Cytochrome P450; Belongs to the cytochrome P450 family. (491 aa)
PEX2_003600Cytochrome P450; Belongs to the cytochrome P450 family. (523 aa)
PEX2_098970Cytochrome P450; Belongs to the cytochrome P450 family. (500 aa)
PEX2_020690Cytochrome P450; Belongs to the cytochrome P450 family. (395 aa)
PEX2_004760Cytochrome P450; Belongs to the cytochrome P450 family. (525 aa)
PEX2_070370Acyl transferase/acyl hydrolase/lysophospholipase. (3971 aa)
PEX2_071930Acyl transferase/acyl hydrolase/lysophospholipase. (2507 aa)
PEX2_040870AMP-dependent synthetase/ligase. (4186 aa)
PEX2_021940Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (397 aa)
PEX2_069690Acyl transferase/acyl hydrolase/lysophospholipase. (2555 aa)
PEX2_065660Cytochrome P450; Belongs to the cytochrome P450 family. (522 aa)
PEX2_031140Uncharacterized protein. (155 aa)
PEX2_066830Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (499 aa)
PEX2_005170Cytochrome P450. (557 aa)
PEX2_069710PKS_KS domain-containing protein. (298 aa)
PEX2_072390AMP-dependent synthetase/ligase. (212 aa)
PEX2_073770Acyl transferase/acyl hydrolase/lysophospholipase. (2617 aa)
PEX2_092060Cytochrome P450. (543 aa)
PEX2_054980Uncharacterized protein. (2368 aa)
cnsIHighly reducing polyketide synthase cnsI; Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals. Communesins are biosynthesized by the coupling of tryptamine and aurantioclavine, two building blocks derived from L- tryptophan. The L-tryptophan decarboxylase cnsB converts L-tryptophan to tryptamine, whereas the tryptophan dimethylallyltransferase cnsF converts L-tryptophan to 4-dimethylallyl tryptophan which is further transformed to aurantioclavine by the [...] (2363 aa)
PEX2_073610Cytochrome P450. (345 aa)
PEX2_074810Cytochrome P450. (517 aa)
PEX2_034170AMP-dependent synthetase/ligase. (987 aa)
PEX2_074880Cytochrome P450; Belongs to the cytochrome P450 family. (520 aa)
cnsCCytochrome P450 monooxygenase cnsC; Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals. Communesins are biosynthesized by the coupling of tryptamine and aurantioclavine, two building blocks derived from L-tryptophan. The L-tryptophan decarboxylase cnsB converts L- tryptophan to tryptamine, whereas the tryptophan dimethylallyltransferase cnsF converts L-tryptophan to 4-dimethylallyl tryptophan which is further transformed to aurantioclavine by the aurantiocla [...] (495 aa)
PEX2_055090Cytochrome P450; Belongs to the cytochrome P450 family. (508 aa)
PEX2_007860Cytochrome P450, E-class, CYP52. (548 aa)
PEX2_001100Male sterility, NAD-binding. (2578 aa)
PEX2_013260Cytochrome P450; Belongs to the cytochrome P450 family. (453 aa)
PEX2_035600Uncharacterized protein family UPF0592. (1110 aa)
PEX2_020720AMP-dependent synthetase/ligase. (5417 aa)
PEX2_035090Cytochrome P450. (762 aa)
PEX2_065490Uncharacterized protein. (169 aa)
PEX2_022130Transferase. (508 aa)
PEX2_081800Cytochrome P450; Belongs to the cytochrome P450 family. (473 aa)
PEX2_081820Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (445 aa)
PEX2_087950Acyl transferase/acyl hydrolase/lysophospholipase. (2499 aa)
PEX2_065890Acyl transferase/acyl hydrolase/lysophospholipase. (2541 aa)
PEX2_101620AMP-dependent synthetase/ligase. (6040 aa)
PEX2_091230Cytochrome P450. (804 aa)
PEX2_013770Uncharacterized protein. (2246 aa)
PEX2_081810Transferase. (487 aa)
PEX2_016080Acyl transferase/acyl hydrolase/lysophospholipase. (2222 aa)
PEX2_074250Uncharacterized protein. (611 aa)
PEX2_014390Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (430 aa)
PEX2_047350Uncharacterized protein. (476 aa)
PEX2_044350Cytochrome P450. (508 aa)
PEX2_042520Cytochrome P450; Belongs to the cytochrome P450 family. (499 aa)
PEX2_012570Pyridine nucleotide-disulfide oxidoreductase, class-II. (2366 aa)
PEX2_011230Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (249 aa)
PEX2_011680Transcription factor, fungi. (634 aa)
PEX2_046390Cytochrome P450; Belongs to the cytochrome P450 family. (591 aa)
PEX2_045550AMP-dependent synthetase/ligase. (5071 aa)
PEX2_042280Polyketide synthase, KR. (138 aa)
PEX2_100300Acyl transferase/acyl hydrolase/lysophospholipase. (2358 aa)
PEX2_011220Male sterility, NAD-binding. (1319 aa)
PEX2_011770Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (413 aa)
PEX2_011600AMP-dependent synthetase/ligase. (584 aa)
PEX2_081780Acyl transferase/acyl hydrolase/lysophospholipase. (2545 aa)
PEX2_012060Cytochrome P450. (497 aa)
PEX2_012410Male sterility, NAD-binding. (2145 aa)
PEX2_017770AMP-dependent synthetase/ligase. (821 aa)
PEX2_011110AMP-dependent synthetase/ligase. (525 aa)
PEX2_077640Transcription factor, fungi. (496 aa)
PEX2_001930Cytochrome P450; Belongs to the cytochrome P450 family. (499 aa)
PEX2_058730FAD dependent oxidoreductase. (461 aa)
PEX2_097700Cytochrome P450. (514 aa)
PEX2_107160Cytochrome P450; Belongs to the cytochrome P450 family. (495 aa)
PEX2_000770Acyl transferase/acyl hydrolase/lysophospholipase. (2138 aa)
PEX2_022760Frag1/DRAM/Sfk1. (248 aa)
PEX2_055830Cytochrome P450, E-class, CYP52. (524 aa)
PEX2_011850Uncharacterized protein. (420 aa)
PEX2_011780AMP-dependent synthetase/ligase. (2179 aa)
PEX2_041040Cytochrome P450, E-class, group I. (1049 aa)
PEX2_023390AMP-dependent synthetase/ligase. (788 aa)
PEX2_103810Cytochrome P450; Belongs to the cytochrome P450 family. (521 aa)
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
Server load: low (18%) [HD]