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patI patI patK patK patH patH PEX2_095640 PEX2_095640 PEX2_016340 PEX2_016340 PEX2_105670 PEX2_105670 PEX2_074780 PEX2_074780 PEX2_074870 PEX2_074870 PEX2_100330 PEX2_100330 PEX2_055770 PEX2_055770 PEX2_003130 PEX2_003130 PEX2_038830 PEX2_038830 PEX2_049410 PEX2_049410 PEX2_083190 PEX2_083190 PEX2_063880 PEX2_063880 PEX2_064700 PEX2_064700 PEX2_022150 PEX2_022150 PEX2_104160 PEX2_104160 cnsG cnsG PEX2_096520 PEX2_096520 PEX2_063700 PEX2_063700 PEX2_094820 PEX2_094820 PEX2_032440 PEX2_032440 PEX2_063780 PEX2_063780 PEX2_048520 PEX2_048520 PEX2_064650 PEX2_064650 PEX2_109670 PEX2_109670 PEX2_048510 PEX2_048510 PEX2_083940 PEX2_083940 PEX2_083520 PEX2_083520 PEX2_038500 PEX2_038500 PEX2_008520 PEX2_008520 PEX2_071950 PEX2_071950 PEX2_090270 PEX2_090270 PEX2_025200 PEX2_025200 PEX2_037910 PEX2_037910 PEX2_032250 PEX2_032250 PEX2_077440 PEX2_077440 PEX2_096900 PEX2_096900 PEX2_098970 PEX2_098970 PEX2_004760 PEX2_004760 PEX2_070370 PEX2_070370 PEX2_040870 PEX2_040870 PEX2_021940 PEX2_021940 PEX2_069710 PEX2_069710 PEX2_072390 PEX2_072390 PEX2_092060 PEX2_092060 PEX2_073610 PEX2_073610 PEX2_034170 PEX2_034170 PEX2_074880 PEX2_074880 PEX2_007860 PEX2_007860 PEX2_035090 PEX2_035090 PEX2_081800 PEX2_081800 PEX2_101620 PEX2_101620 PEX2_091230 PEX2_091230 PEX2_014390 PEX2_014390 PEX2_042520 PEX2_042520 PEX2_012570 PEX2_012570 PEX2_046390 PEX2_046390 PEX2_042280 PEX2_042280 PEX2_011600 PEX2_011600 PEX2_081780 PEX2_081780 PEX2_012410 PEX2_012410 PEX2_017770 PEX2_017770 PEX2_011110 PEX2_011110 PEX2_055830 PEX2_055830 PEX2_011780 PEX2_011780 PEX2_023390 PEX2_023390 PEX2_103810 PEX2_103810
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
patICytochrome P450 monooxygenase patI; Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units. The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol). These first [...] (526 aa)
patK6-methylcalicylic acide synthase; 6-methylcalicylic acide synthase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units. The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m- cresol (also known as 3-methylphenol). These firs [...] (1776 aa)
patHCytochrome P450 monooxygenase patH; Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units. The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol). These first [...] (524 aa)
PEX2_095640Ribosomal protein L13, eukaryotic/archaeal. (792 aa)
PEX2_016340AMP-dependent synthetase/ligase. (549 aa)
PEX2_105670AMP-dependent synthetase/ligase. (811 aa)
PEX2_074780Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (512 aa)
PEX2_074870Acyl transferase/acyl hydrolase/lysophospholipase. (2137 aa)
PEX2_100330Chloroperoxidase. (808 aa)
PEX2_055770AMP-dependent synthetase/ligase. (1435 aa)
PEX2_003130Cytochrome P450; Belongs to the cytochrome P450 family. (490 aa)
PEX2_038830Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (380 aa)
PEX2_049410Transcription factor, fungi. (595 aa)
PEX2_083190Male sterility, NAD-binding. (2332 aa)
PEX2_063880Cytochrome P450; Belongs to the cytochrome P450 family. (381 aa)
PEX2_064700AMP-dependent synthetase/ligase. (543 aa)
PEX2_022150Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (514 aa)
PEX2_104160AMP-dependent synthetase/ligase. (2108 aa)
cnsGAcyl-CoA ligase cnsG; Acyl-CoA ligase; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals. Communesins are biosynthesized by the coupling of tryptamine and aurantioclavine, two building blocks derived from L-tryptophan. The L- tryptophan decarboxylase cnsB converts L-tryptophan to tryptamine, whereas the tryptophan dimethylallyltransferase cnsF converts L- tryptophan to 4-dimethylallyl tryptophan which is further transformed to aurantioclavine by the aurantioclavine synthase cnsA, probabl [...] (481 aa)
PEX2_096520Cytochrome P450. (550 aa)
PEX2_063700Carrier domain-containing protein. (1009 aa)
PEX2_094820Uncharacterized protein. (577 aa)
PEX2_032440AMP-dependent synthetase/ligase. (7287 aa)
PEX2_063780Acyl transferase/acyl hydrolase/lysophospholipase. (1783 aa)
PEX2_048520Polyketide synthase, KR. (355 aa)
PEX2_064650Carrier domain-containing protein. (1263 aa)
PEX2_109670Acyl transferase/acyl hydrolase/lysophospholipase. (2492 aa)
PEX2_048510Acyl transferase/acyl hydrolase/lysophospholipase. (1128 aa)
PEX2_083940AMP-dependent synthetase/ligase. (3239 aa)
PEX2_083520Cytochrome P450; Belongs to the cytochrome P450 family. (519 aa)
PEX2_038500AMP-binding_C domain-containing protein. (131 aa)
PEX2_008520Cytochrome P450; Belongs to the cytochrome P450 family. (471 aa)
PEX2_071950Cytochrome P450; Belongs to the cytochrome P450 family. (519 aa)
PEX2_090270Cytochrome P450. (373 aa)
PEX2_025200AMP-dependent synthetase/ligase. (2645 aa)
PEX2_037910Polyketide synthase, KR. (443 aa)
PEX2_032250Male sterility, NAD-binding. (601 aa)
PEX2_077440Male sterility, NAD-binding. (1276 aa)
PEX2_096900Uncharacterized protein. (601 aa)
PEX2_098970Cytochrome P450; Belongs to the cytochrome P450 family. (500 aa)
PEX2_004760Cytochrome P450; Belongs to the cytochrome P450 family. (525 aa)
PEX2_070370Acyl transferase/acyl hydrolase/lysophospholipase. (3971 aa)
PEX2_040870AMP-dependent synthetase/ligase. (4186 aa)
PEX2_021940Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (397 aa)
PEX2_069710PKS_KS domain-containing protein. (298 aa)
PEX2_072390AMP-dependent synthetase/ligase. (212 aa)
PEX2_092060Cytochrome P450. (543 aa)
PEX2_073610Cytochrome P450. (345 aa)
PEX2_034170AMP-dependent synthetase/ligase. (987 aa)
PEX2_074880Cytochrome P450; Belongs to the cytochrome P450 family. (520 aa)
PEX2_007860Cytochrome P450, E-class, CYP52. (548 aa)
PEX2_035090Cytochrome P450. (762 aa)
PEX2_081800Cytochrome P450; Belongs to the cytochrome P450 family. (473 aa)
PEX2_101620AMP-dependent synthetase/ligase. (6040 aa)
PEX2_091230Cytochrome P450. (804 aa)
PEX2_014390Cytochrome P450, E-class, group I; Belongs to the cytochrome P450 family. (430 aa)
PEX2_042520Cytochrome P450; Belongs to the cytochrome P450 family. (499 aa)
PEX2_012570Pyridine nucleotide-disulfide oxidoreductase, class-II. (2366 aa)
PEX2_046390Cytochrome P450; Belongs to the cytochrome P450 family. (591 aa)
PEX2_042280Polyketide synthase, KR. (138 aa)
PEX2_011600AMP-dependent synthetase/ligase. (584 aa)
PEX2_081780Acyl transferase/acyl hydrolase/lysophospholipase. (2545 aa)
PEX2_012410Male sterility, NAD-binding. (2145 aa)
PEX2_017770AMP-dependent synthetase/ligase. (821 aa)
PEX2_011110AMP-dependent synthetase/ligase. (525 aa)
PEX2_055830Cytochrome P450, E-class, CYP52. (524 aa)
PEX2_011780AMP-dependent synthetase/ligase. (2179 aa)
PEX2_023390AMP-dependent synthetase/ligase. (788 aa)
PEX2_103810Cytochrome P450; Belongs to the cytochrome P450 family. (521 aa)
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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