RNA polymerase II accessory factor, Cdc73.

Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

RNA polymerase II accessory factor, Cdc73.

DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

RNA polymerase II accessory factor, Cdc73.

RNA polymerase II-associated, Paf1.

RNA polymerase II accessory factor, Cdc73.

Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.

RNA polymerase II accessory factor, Cdc73.

RNA polymerase II, Rpb4, core.

RNA polymerase II accessory factor, Cdc73.

DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

RNA polymerase II accessory factor, Cdc73.

Histone-fold.

RNA polymerase II accessory factor, Cdc73.

Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type.

RNA polymerase II accessory factor, Cdc73.

Histone H2B; Belongs to the histone H2B family.

RNA polymerase II accessory factor, Cdc73.

Histone H2A; Belongs to the histone H2A family.

RNA polymerase II accessory factor, Cdc73.

Nucleic acid-binding, OB-fold.

RNA polymerase II accessory factor, Cdc73.

DNA-directed RNA polymerase, M/15kDa subunit.

RNA polymerase II accessory factor, Cdc73.

Transcription factor IIS, N-terminal.

RNA polymerase II accessory factor, Cdc73.

Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

RNA polymerase II accessory factor, Cdc73.

Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

RNA polymerase II accessory factor, Cdc73.

FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]

RNA polymerase II accessory factor, Cdc73.

Plus-3.

RNA polymerase II accessory factor, Cdc73.

DNA-directed RNA polymerase, subunit N/Rpb10.

RNA polymerase II accessory factor, Cdc73.

DNA-directed RNA polymerase, dimerization.

RNA polymerase II accessory factor, Cdc73.

Uncharacterized protein.