STRINGSTRING
PIF1 PIF1 PEX2_110050 PEX2_110050 PEX2_013420 PEX2_013420 PEX2_098750 PEX2_098750 PEX2_035630 PEX2_035630 PEX2_037050 PEX2_037050 PEX2_096090 PEX2_096090 PEX2_108620 PEX2_108620 PEX2_061050 PEX2_061050 PEX2_057540 PEX2_057540 PEX2_103290 PEX2_103290 PEX2_077840 PEX2_077840 PEX2_076170 PEX2_076170 PEX2_075890 PEX2_075890 PEX2_071530 PEX2_071530 PEX2_084750 PEX2_084750 PEX2_052350 PEX2_052350 PEX2_076180 PEX2_076180 PEX2_035860 PEX2_035860 PEX2_052340 PEX2_052340 PEX2_099530 PEX2_099530 PEX2_021140 PEX2_021140 PEX2_014080 PEX2_014080 PEX2_054960 PEX2_054960 PEX2_087970 PEX2_087970 PEX2_087850 PEX2_087850 PEX2_073500 PEX2_073500 PEX2_044610 PEX2_044610 PEX2_011170 PEX2_011170 PEX2_003200 PEX2_003200 KAE1-2 KAE1-2 PEX2_016920 PEX2_016920 PEX2_068430 PEX2_068430 PEX2_050030 PEX2_050030 PEX2_101650 PEX2_101650
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (720 aa)
PEX2_110050Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
PEX2_013420Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (431 aa)
PEX2_098750Nucleotide-binding, alpha-beta plait. (380 aa)
PEX2_035630Uncharacterized protein. (124 aa)
PEX2_037050DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (628 aa)
PEX2_096090Ubiquitin system component Cue. (874 aa)
PEX2_108620Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (1107 aa)
PEX2_061050EthD domain-containing protein. (155 aa)
PEX2_057540ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (510 aa)
PEX2_103290Uncharacterized protein. (1669 aa)
PEX2_077840Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (305 aa)
PEX2_076170PIK-related kinase, FATC; Belongs to the PI3/PI4-kinase family. (2172 aa)
PEX2_075890Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1227 aa)
PEX2_071530DNA repair metallo-beta-lactamase. (725 aa)
PEX2_084750Telomere end binding protein. (601 aa)
PEX2_052350Uncharacterized protein. (204 aa)
PEX2_076180Telomere-length maintenance and DNA damage repair. (400 aa)
PEX2_035860ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (712 aa)
PEX2_052340PIK-related kinase, FATC; Belongs to the PI3/PI4-kinase family. (1956 aa)
PEX2_099530Rap1-interacting factor 1 N-terminal. (1730 aa)
PEX2_021140Recombination/repair protein Rad50. (1383 aa)
PEX2_014080Helicase, C-terminal. (1417 aa)
PEX2_054960Uncharacterized protein. (243 aa)
PEX2_087970HTH APSES-type domain-containing protein. (444 aa)
PEX2_087850HTH myb-type domain-containing protein. (848 aa)
PEX2_073500DNA helicase, ATP-dependent, Ku type. (653 aa)
PEX2_044610Helicase, C-terminal. (1663 aa)
PEX2_011170Mre11, DNA-binding; Belongs to the MRE11/RAD32 family. (1382 aa)
PEX2_003200Telomere_reg-2 domain-containing protein. (1007 aa)
KAE1-2tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (364 aa)
PEX2_016920HD domain-containing protein. (235 aa)
PEX2_068430DNA repair metallo-beta-lactamase. (846 aa)
PEX2_050030SANT domain-containing protein. (851 aa)
PEX2_101650DNA recombination/repair protein RecA, monomer-monomer interface; Belongs to the RecA family. (637 aa)
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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