80 items (Penicillium expansum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PEX2_077900	Uncharacterized protein. (220 aa)
	PEX2_032390	Up-frameshift suppressor 2. (1271 aa)
	PEX2_073950	RAI1 domain-containing protein. (361 aa)
	PEX2_092260	RNA recognition motif domain, eukaryote. (1511 aa)
	PEX2_037570	Helicase, C-terminal; Belongs to the DEAD box helicase family. (525 aa)
	PEX2_077940	Exosome complex RNA-binding protein 1/RRP40/RRP4. (272 aa)
	PEX2_033520	Exosome complex component CSL4. (246 aa)
	PEX2_081460	Uncharacterized protein. (427 aa)
	PEX2_019370	Btz domain-containing protein. (634 aa)
	PEX2_038860	Nucleic acid-binding, OB-fold. (169 aa)
	PEX2_015190	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (686 aa)
	PEX2_042050	Ribonuclease CAF1. (554 aa)
	PEX2_021030	Leucine-rich repeat, typical subtype. (750 aa)
	PEX2_046780	Nuclear cap-binding protein subunit 2. (190 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (681 aa)
	PEX2_085730	Exoribonuclease, phosphorolytic domain 2. (249 aa)
	PEX2_084960	Not CCR4-Not complex component, N-terminal. (584 aa)
	PEX2_091180	Exoribonuclease, phosphorolytic domain 1. (388 aa)
	PEX2_017250	Uncharacterized protein. (449 aa)
	PEX2_033920	Armadillo-like helical. (820 aa)
	PEX2_021780	Ribonucleoprotein LSM domain, eukaryotic/archaea-type. (821 aa)
	PEX2_000350	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1397 aa)
	PEX2_086610	mRNA decapping protein 2, Box A. (850 aa)
	PEX2_034030	Ribonuclease III. (319 aa)
	PEX2_004450	Translation elongation/initiation factor/Ribosomal, beta-barrel. (800 aa)
	PEX2_073040	DNA/RNA-binding domain, Est1-type. (742 aa)
	PEX2_093560	Exoribonuclease, phosphorolytic domain 1. (384 aa)
	PEX2_073400	Dcp1-like decapping. (319 aa)
	PEX2_074140	Uncharacterized protein. (179 aa)
	PEX2_105520	Uncharacterized protein. (513 aa)
	PEX2_017070	Nucleotide-binding, alpha-beta plait. (396 aa)
	PEX2_103260	Ribonuclease II/R; Belongs to the RNR ribonuclease family. (1031 aa)
	PEX2_070920	Single-stranded nucleic acid binding R3H. (582 aa)
	PEX2_047140	Exoribonuclease, phosphorolytic domain 1. (324 aa)
	PEX2_104870	Uncharacterized protein. (496 aa)
	PEX2_070930	Histone H2A; Belongs to the histone H2A family. (139 aa)
	PEX2_019180	Helicase, C-terminal; Belongs to the DEAD box helicase family. (562 aa)
	PEX2_107720	Topoisomerase II-associated protein PAT1. (824 aa)
	PEX2_029590	Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (192 aa)
	PEX2_110110	Sterile alpha motif, type 2. (608 aa)
	PEX2_083410	Major facilitator superfamily domain, general substrate transporter; Belongs to the MT-A70-like family. (2125 aa)
	PEX2_083380	Scavenger mRNA decapping enzyme, N-terminal. (334 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (83 aa)
	PEX2_037250	Ctr copper transporter. (488 aa)
	PEX2_064190	Exon junction complex, Pym. (217 aa)
	PEX2_020830	RNA polymerase II, Rpb4, core. (148 aa)
	PEX2_043530	Ribonuclease CAF1. (477 aa)
	PEX2_078940	RNA recognition motif domain, eukaryote. (482 aa)
	PEX2_078540	Exosome-associated factor Rrp6, N-terminal. (754 aa)
	PEX2_012760	U6 snRNA-associated Sm-like protein LSm7. (125 aa)
	PEX2_094660	Helicase, C-terminal. (1307 aa)
	PEX2_039150	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (597 aa)
	PEX2_047900	Tetratricopeptide-like helical. (1451 aa)
	PEX2_060440	Uncharacterized protein. (597 aa)
	PEX2_049270	WD_REPEATS_REGION domain-containing protein. (309 aa)
	PEX2_022680	Translation Initiation factor eIF-4e; Belongs to the eukaryotic initiation factor 4E family. (238 aa)
	PEX2_028080	CCR4-Not complex component, Not1, C-terminal. (2306 aa)
	PEX2_014210	Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal. (710 aa)
	PEX2_055890	Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (403 aa)
	PEX2_091300	Uncharacterized protein. (880 aa)
	PEX2_022220	Uncharacterized protein. (358 aa)
	PEX2_012020	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1028 aa)
	PEX2_032090	Uncharacterized protein. (1498 aa)
	PEX2_025550	Armadillo-like helical. (904 aa)
	PEX2_035430	Uncharacterized protein. (276 aa)
	PEX2_034820	Uncharacterized protein. (266 aa)
	PEX2_093770	AAA_12 domain-containing protein. (201 aa)
	PEX2_077080	Regulator of nonsense-mediated decay, UPF3. (551 aa)
	PEX2_060770	Helicase ATP-binding domain-containing protein. (1079 aa)
	PEX2_040170	Nucleotide-binding, alpha-beta plait. (592 aa)
	PEX2_074130	RNA recognition motif 2. (709 aa)
	PEX2_074030	MIF4-like, type 1/2/3. (822 aa)
	PEX2_072220	zf-C3H1 domain-containing protein. (996 aa)
	PEX2_084670	Uncharacterized protein. (1132 aa)
	PEX2_066560	Zinc finger, CCCH-type. (443 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (177 aa)
	PEX2_075850	Winged helix-turn-helix transcription repressor DNA-binding; Belongs to the cullin family. (869 aa)
	PEX2_019900	Sas10/Utp3/C1D. (239 aa)
	PEX2_019400	Ribosomal protein L27. (392 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1170 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM1	LSM5	A0A0A2JT10	A0A0A2IKZ1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.979
LSM1	PEX2_000350	A0A0A2JT10	A0A0A2JYU1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.940
LSM1	PEX2_012760	A0A0A2JT10	A0A0A2JI16	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	U6 snRNA-associated Sm-like protein LSm7.	0.978
LSM1	PEX2_015190	A0A0A2JT10	A0A0A2KBV4	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.	0.847
LSM1	PEX2_019180	A0A0A2JT10	A0A0A2IEF6	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Helicase, C-terminal; Belongs to the DEAD box helicase family.	0.586
LSM1	PEX2_021030	A0A0A2JT10	A0A0A2K7U0	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Leucine-rich repeat, typical subtype.	0.438
LSM1	PEX2_021780	A0A0A2JT10	A0A0A2JZZ3	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Ribonucleoprotein LSM domain, eukaryotic/archaea-type.	0.980
LSM1	PEX2_022680	A0A0A2JT10	A0A0A2J7B9	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Translation Initiation factor eIF-4e; Belongs to the eukaryotic initiation factor 4E family.	0.558
LSM1	PEX2_034820	A0A0A2JT10	A0A0A2IVH5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.878
LSM1	PEX2_037570	A0A0A2JT10	A0A0A2KXL3	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Helicase, C-terminal; Belongs to the DEAD box helicase family.	0.981
LSM1	PEX2_047900	A0A0A2JT10	A0A0A2JDM3	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Tetratricopeptide-like helical.	0.439
LSM1	PEX2_060770	A0A0A2JT10	A0A0A2IUG9	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Helicase ATP-binding domain-containing protein.	0.504
LSM1	PEX2_073400	A0A0A2JT10	A0A0A2I0M8	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Dcp1-like decapping.	0.839
LSM1	PEX2_084670	A0A0A2JT10	A0A0A2JTN3	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.504
LSM1	PEX2_086610	A0A0A2JT10	A0A0A2JYF2	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	mRNA decapping protein 2, Box A.	0.878
LSM1	PEX2_093770	A0A0A2JT10	A0A0A2IVD2	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	AAA_12 domain-containing protein.	0.470
LSM1	PEX2_094660	A0A0A2JT10	A0A0A2JFA8	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Helicase, C-terminal.	0.659
LSM1	PEX2_107720	A0A0A2JT10	A0A0A2IF88	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Topoisomerase II-associated protein PAT1.	0.975
LSM5	LSM1	A0A0A2IKZ1	A0A0A2JT10	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	0.979
LSM5	PEX2_000350	A0A0A2IKZ1	A0A0A2JYU1	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.813