15 items (Penicillium expansum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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protein homology

Your Input:
	PEX2_030060	Dihydrolipoamide succinyltransferase. (557 aa)
	PEX2_020450	Peripheral subunit-binding (PSBD) domain-containing protein. (289 aa)
	PEX2_037510	Biotin/lipoyl attachment. (455 aa)
	PEX2_007980	Acetyl-coenzyme A synthetase. (669 aa)
	PEX2_045650	Uncharacterized protein. (700 aa)
	PEX2_077210	Probable acetate kinase. (459 aa)
	PEX2_067440	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (435 aa)
	PEX2_029570	ATP-grasp fold, succinyl-CoA synthetase-type. (485 aa)
	PEX2_107670	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (483 aa)
	PEX2_031930	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (405 aa)
	PEX2_101920	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (484 aa)
	PEX2_034700	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (532 aa)
	PEX2_057650	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (404 aa)
	PEX2_035560	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (461 aa)
	PEX2_051650	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (376 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PEX2_007980	PEX2_020450	A0A0A2I4P4	A0A0A2KS29	Acetyl-coenzyme A synthetase.	Peripheral subunit-binding (PSBD) domain-containing protein.	0.654
PEX2_007980	PEX2_029570	A0A0A2I4P4	A0A0A2JIF3	Acetyl-coenzyme A synthetase.	ATP-grasp fold, succinyl-CoA synthetase-type.	0.474
PEX2_007980	PEX2_030060	A0A0A2I4P4	A0A0A2IA41	Acetyl-coenzyme A synthetase.	Dihydrolipoamide succinyltransferase.	0.513
PEX2_007980	PEX2_031930	A0A0A2I4P4	A0A0A2J3P8	Acetyl-coenzyme A synthetase.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.911
PEX2_007980	PEX2_034700	A0A0A2I4P4	A0A0A2IRB1	Acetyl-coenzyme A synthetase.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.508
PEX2_007980	PEX2_035560	A0A0A2I4P4	A0A0A2IP70	Acetyl-coenzyme A synthetase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.590
PEX2_007980	PEX2_037510	A0A0A2I4P4	A0A0A2I126	Acetyl-coenzyme A synthetase.	Biotin/lipoyl attachment.	0.513
PEX2_007980	PEX2_045650	A0A0A2I4P4	A0A0A2KK29	Acetyl-coenzyme A synthetase.	Uncharacterized protein.	0.892
PEX2_007980	PEX2_051650	A0A0A2I4P4	A0A0A2IFV5	Acetyl-coenzyme A synthetase.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.905
PEX2_007980	PEX2_067440	A0A0A2I4P4	A0A0A2JS62	Acetyl-coenzyme A synthetase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.590
PEX2_007980	PEX2_077210	A0A0A2I4P4	A0A0A2KEA4	Acetyl-coenzyme A synthetase.	Probable acetate kinase.	0.885
PEX2_007980	PEX2_101920	A0A0A2I4P4	A0A0A2ISK7	Acetyl-coenzyme A synthetase.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.899
PEX2_020450	PEX2_007980	A0A0A2KS29	A0A0A2I4P4	Peripheral subunit-binding (PSBD) domain-containing protein.	Acetyl-coenzyme A synthetase.	0.654
PEX2_020450	PEX2_029570	A0A0A2KS29	A0A0A2JIF3	Peripheral subunit-binding (PSBD) domain-containing protein.	ATP-grasp fold, succinyl-CoA synthetase-type.	0.906
PEX2_020450	PEX2_030060	A0A0A2KS29	A0A0A2IA41	Peripheral subunit-binding (PSBD) domain-containing protein.	Dihydrolipoamide succinyltransferase.	0.928
PEX2_020450	PEX2_031930	A0A0A2KS29	A0A0A2J3P8	Peripheral subunit-binding (PSBD) domain-containing protein.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.993
PEX2_020450	PEX2_034700	A0A0A2KS29	A0A0A2IRB1	Peripheral subunit-binding (PSBD) domain-containing protein.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.544
PEX2_020450	PEX2_035560	A0A0A2KS29	A0A0A2IP70	Peripheral subunit-binding (PSBD) domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.641
PEX2_020450	PEX2_037510	A0A0A2KS29	A0A0A2I126	Peripheral subunit-binding (PSBD) domain-containing protein.	Biotin/lipoyl attachment.	0.928
PEX2_020450	PEX2_045650	A0A0A2KS29	A0A0A2KK29	Peripheral subunit-binding (PSBD) domain-containing protein.	Uncharacterized protein.	0.654