STRINGSTRING
PEX2_082190 PEX2_082190 PEX2_100340 PEX2_100340 PEX2_074560 PEX2_074560 PEX2_073460 PEX2_073460 PEX2_052300 PEX2_052300 PEX2_073860 PEX2_073860 cprA cprA PEX2_067440 PEX2_067440 PEX2_014360 PEX2_014360 PEX2_090860 PEX2_090860 PEX2_031080 PEX2_031080 PEX2_007400 PEX2_007400 PEX2_094910 PEX2_094910 PEX2_022870 PEX2_022870 PEX2_060310 PEX2_060310 PEX2_107670 PEX2_107670 PEX2_043700 PEX2_043700 PEX2_068680 PEX2_068680 PEX2_032050 PEX2_032050 PEX2_084500 PEX2_084500 PEX2_006780 PEX2_006780 PEX2_035560 PEX2_035560 PEX2_079190 PEX2_079190 PEX2_034700 PEX2_034700 PEX2_109400 PEX2_109400 PEX2_045150 PEX2_045150 PEX2_100330 PEX2_100330 PEX2_053720 PEX2_053720 PEX2_072720 PEX2_072720 PEX2_074060 PEX2_074060 PEX2_036020 PEX2_036020 PEX2_043270 PEX2_043270 PEX2_031180 PEX2_031180 PEX2_036620 PEX2_036620 cnsG cnsG PEX2_095320 PEX2_095320 PEX2_094920 PEX2_094920 PEX2_011260 PEX2_011260 PEX2_081610 PEX2_081610 PEX2_011600 PEX2_011600
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PEX2_082190Cytochrome P450; Belongs to the cytochrome P450 family. (537 aa)
PEX2_100340Uncharacterized protein. (90 aa)
PEX2_074560Uncharacterized protein. (254 aa)
PEX2_073460Squalene epoxidase. (475 aa)
PEX2_052300Fatty acid hydroxylase; Belongs to the sterol desaturase family. (289 aa)
PEX2_073860Riboflavin synthase-like beta-barrel. (386 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (695 aa)
PEX2_0674403-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (435 aa)
PEX2_014360Uncharacterized protein. (250 aa)
PEX2_090860Uncharacterized protein. (223 aa)
PEX2_031080Fatty acid hydroxylase; Belongs to the sterol desaturase family. (261 aa)
PEX2_007400Short-chain dehydrogenase/reductase SDR. (440 aa)
PEX2_094910Crotonase, core. (272 aa)
PEX2_022870NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450. (707 aa)
PEX2_060310Ergosterol biosynthesis ERG4/ERG24. (491 aa)
PEX2_107670Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (483 aa)
PEX2_043700Uncharacterized protein. (275 aa)
PEX2_0686803-beta hydroxysteroid dehydrogenase/isomerase. (412 aa)
PEX2_032050Ergosterol biosynthesis ERG4/ERG24. (531 aa)
PEX2_084500Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
PEX2_006780Cytochrome P450; Belongs to the cytochrome P450 family. (534 aa)
PEX2_0355603-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (461 aa)
PEX2_079190Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (377 aa)
PEX2_034700Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (532 aa)
PEX2_109400NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (319 aa)
PEX2_045150Fatty acid hydroxylase; Belongs to the sterol desaturase family. (320 aa)
PEX2_100330Chloroperoxidase. (808 aa)
PEX2_053720Uncharacterized protein. (643 aa)
PEX2_072720SET domain-containing protein. (1064 aa)
PEX2_074060Fatty acid hydroxylase; Belongs to the sterol desaturase family. (350 aa)
PEX2_036020Ergosterol biosynthesis ERG4/ERG24. (496 aa)
PEX2_043270Fatty acid hydroxylase; Belongs to the sterol desaturase family. (312 aa)
PEX2_031180Uncharacterized protein. (294 aa)
PEX2_0366203-beta hydroxysteroid dehydrogenase/isomerase. (349 aa)
cnsGAcyl-CoA ligase cnsG; Acyl-CoA ligase; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals. Communesins are biosynthesized by the coupling of tryptamine and aurantioclavine, two building blocks derived from L-tryptophan. The L- tryptophan decarboxylase cnsB converts L-tryptophan to tryptamine, whereas the tryptophan dimethylallyltransferase cnsF converts L- tryptophan to 4-dimethylallyl tryptophan which is further transformed to aurantioclavine by the aurantioclavine synthase cnsA, probabl [...] (481 aa)
PEX2_095320Crotonase, core. (287 aa)
PEX2_094920Acyl-CoA N-acyltransferase. (442 aa)
PEX2_011260Erg28. (135 aa)
PEX2_081610Squalene/phytoene synthase. (473 aa)
PEX2_011600AMP-dependent synthetase/ligase. (584 aa)
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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