STRINGSTRING
EFM6 EFM6 TRM8 TRM8 PEX2_089910 PEX2_089910 PEX2_029550 PEX2_029550 PEX2_107640 PEX2_107640 PEX2_029920 PEX2_029920 PEX2_018560 PEX2_018560 PEX2_108590 PEX2_108590 EFM4 EFM4 PEX2_090760 PEX2_090760 PEX2_087770 PEX2_087770 PEX2_048240 PEX2_048240 PEX2_050560 PEX2_050560 PEX2_076430 PEX2_076430 PEX2_023380 PEX2_023380 COQ5 COQ5 EFM7 EFM7 PEX2_065380 PEX2_065380 PEX2_110660 PEX2_110660 TRM5 TRM5 PEX2_074070 PEX2_074070 PEX2_095030 PEX2_095030 PEX2_070310 PEX2_070310 PEX2_062850 PEX2_062850 PEX2_075430 PEX2_075430 PEX2_019540 PEX2_019540 PEX2_060890 PEX2_060890 PEX2_082690 PEX2_082690 PEX2_065910 PEX2_065910 PEX2_006250 PEX2_006250 PEX2_075640 PEX2_075640 PEX2_097990 PEX2_097990 PEX2_087010 PEX2_087010 PEX2_087460 PEX2_087460 PEX2_054660 PEX2_054660 PEX2_102760 PEX2_102760 PEX2_102430 PEX2_102430 PEX2_013930 PEX2_013930 PEX2_019800 PEX2_019800 PEX2_012250 PEX2_012250 PEX2_046330 PEX2_046330 PEX2_011540 PEX2_011540 PEX2_012720 PEX2_012720 PEX2_046420 PEX2_046420 PEX2_044040 PEX2_044040 SPB1 SPB1 PEX2_025980 PEX2_025980 PEX2_085790 PEX2_085790 PEX2_043380 PEX2_043380 TRM82 TRM82 PEX2_042800 PEX2_042800 PEX2_051320 PEX2_051320 PEX2_012370 PEX2_012370 PEX2_051460 PEX2_051460 PEX2_086420 PEX2_086420 PEX2_058020 PEX2_058020 PEX2_005640 PEX2_005640 PEX2_046710 PEX2_046710 PEX2_037530 PEX2_037530 PEX2_089520 PEX2_089520 PEX2_015080 PEX2_015080 PEX2_032800 PEX2_032800 PEX2_094740 PEX2_094740 PEX2_077480 PEX2_077480 PEX2_006370 PEX2_006370 PEX2_003410 PEX2_003410 PEX2_038610 PEX2_038610 PEX2_036870 PEX2_036870 PEX2_079190 PEX2_079190 PEX2_034290 PEX2_034290 COQ3 COQ3 PEX2_021070 PEX2_021070 PEX2_060540 PEX2_060540 PEX2_049500 PEX2_049500 PEX2_060910 PEX2_060910 PEX2_103370 PEX2_103370 PEX2_044970 PEX2_044970 PEX2_042970 PEX2_042970 PEX2_051470 PEX2_051470 PEX2_051620 PEX2_051620 PEX2_013160 PEX2_013160 PEX2_105180 PEX2_105180 PEX2_087940 PEX2_087940 PEX2_089750 PEX2_089750 PEX2_094420 PEX2_094420 PEX2_101310 PEX2_101310 PEX2_010090 PEX2_010090 PEX2_104050 PEX2_104050 PEX2_070710 PEX2_070710 PEX2_074080 PEX2_074080 PEX2_008020 PEX2_008020 PEX2_012690 PEX2_012690 PEX2_019880 PEX2_019880 PEX2_070470 PEX2_070470 PEX2_015330 PEX2_015330 PEX2_028380 PEX2_028380 PEX2_094600 PEX2_094600 PEX2_007230 PEX2_007230 PEX2_010500 PEX2_010500 PEX2_109960 PEX2_109960 PEX2_049390 PEX2_049390 PEX2_047860 PEX2_047860 PEX2_060740 PEX2_060740 PEX2_057340 PEX2_057340 PEX2_039010 PEX2_039010 PEX2_008870 PEX2_008870
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFM6Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily. (249 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (339 aa)
PEX2_089910Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (348 aa)
PEX2_029550SET domain-containing protein. (328 aa)
PEX2_107640Uncharacterized protein. (262 aa)
PEX2_029920Uncharacterized protein. (481 aa)
PEX2_018560Uncharacterized protein. (498 aa)
PEX2_108590Ribosomal RNA large subunit methyltransferase E. (701 aa)
EFM4Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family. (335 aa)
PEX2_090760Uncharacterized protein. (86 aa)
PEX2_087770(Uracil-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (531 aa)
PEX2_048240HAD_SAK_1 domain-containing protein. (576 aa)
PEX2_050560Siroheme synthase domain 3; Belongs to the precorrin methyltransferase family. (655 aa)
PEX2_076430N2227 domain-containing protein. (422 aa)
PEX2_023380Uncharacterized protein. (345 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (314 aa)
EFM7Protein N-terminal and lysine N-methyltransferase EFM7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono-and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family. (270 aa)
PEX2_065380Uncharacterized protein. (826 aa)
PEX2_110660Arginine N-methyltransferase 2; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12. (418 aa)
TRM5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (480 aa)
PEX2_074070Uncharacterized protein. (251 aa)
PEX2_095030Uncharacterized protein. (53 aa)
PEX2_070310Uncharacterized protein. (362 aa)
PEX2_062850Uncharacterized protein. (448 aa)
PEX2_075430N2227 domain-containing protein. (425 aa)
PEX2_019540Ribosomal biogenesis, methyltransferase, EMG1/NEP1. (259 aa)
PEX2_060890Methyltransf_25 domain-containing protein. (292 aa)
PEX2_082690rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (390 aa)
PEX2_065910Uncharacterized protein. (265 aa)
PEX2_006250Phytanoyl-CoA dioxygenase. (315 aa)
PEX2_075640Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (232 aa)
PEX2_097990Uncharacterized protein. (298 aa)
PEX2_087010Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (505 aa)
PEX2_087460Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (825 aa)
PEX2_054660Histidine phosphatase superfamily, clade-1. (595 aa)
PEX2_102760DUF2431 domain-containing protein. (401 aa)
PEX2_102430WW/Rsp5/WWP; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (884 aa)
PEX2_013930Uncharacterized protein. (258 aa)
PEX2_019800Uncharacterized protein. (790 aa)
PEX2_012250Leucine carboxyl methyltransferase, eukaryotic. (625 aa)
PEX2_046330Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (303 aa)
PEX2_011540Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (573 aa)
PEX2_012720Fibrillarin. (328 aa)
PEX2_046420Bicoid-interacting 3. (234 aa)
PEX2_044040tRNA (Adenine(58)-N(1))-methyltransferase catalytic subunit GCD14. (498 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (819 aa)
PEX2_025980RuBisCO-cytochrome methylase, RMS1. (487 aa)
PEX2_085790BTB domain-containing protein. (215 aa)
PEX2_043380Homocysteine S-methyltransferase. (344 aa)
TRM82tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (494 aa)
PEX2_042800Vacuolar protein sorting-associated, VPS28. (340 aa)
PEX2_051320Uncharacterized protein family, methyltransferase, Williams-Beuren syndrome. (280 aa)
PEX2_012370Tetrapyrrole methylase, subdomain 1. (285 aa)
PEX2_051460Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1209 aa)
PEX2_08642025S rRNA adenine-N(1) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA; Belongs to the BMT2 family. (282 aa)
PEX2_058020BTB domain-containing protein. (228 aa)
PEX2_005640WD_REPEATS_REGION domain-containing protein. (478 aa)
PEX2_046710Histone-lysine N-methyltransferase SET9. (671 aa)
PEX2_037530Protein-L-isoaspartate O-methyltransferase. (257 aa)
PEX2_089520Uncharacterized protein. (346 aa)
PEX2_015080mRNA cap guanine-N7 methyltransferase. (540 aa)
PEX2_032800Uncharacterized protein. (825 aa)
PEX2_094740Zinc finger, MYND-type. (612 aa)
PEX2_077480Zinc finger, PHD-type. (879 aa)
PEX2_006370Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family. (974 aa)
PEX2_003410O-methyltransferase, family 3. (225 aa)
PEX2_038610Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (494 aa)
PEX2_036870Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (385 aa)
PEX2_079190Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (377 aa)
PEX2_034290Uncharacterized protein. (361 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (1024 aa)
PEX2_021070tRNA (Adenine(58)-N(1))-methyltransferase catalytic subunit GCD14. (433 aa)
PEX2_060540Uncharacterized protein. (494 aa)
PEX2_049500Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC). (201 aa)
PEX2_060910Uncharacterized protein. (489 aa)
PEX2_103370tRNA guanosine-2'-O-methyltransferase, TRM11. (454 aa)
PEX2_044970Uncharacterized protein. (433 aa)
PEX2_042970Uncharacterized protein. (163 aa)
PEX2_051470Uncharacterized protein family UPF0434/Trm112. (126 aa)
PEX2_051620tRNA (Guanine(26)-N(2))-dimethyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (697 aa)
PEX2_013160C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (611 aa)
PEX2_105180tRNA/rRNA methyltransferase, SpoU. (620 aa)
PEX2_087940Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (234 aa)
PEX2_089750Shr3 amino acid permease chaperone. (224 aa)
PEX2_094420Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (507 aa)
PEX2_101310Aminoglycoside phosphotransferase. (214 aa)
PEX2_010090Uncharacterized protein. (503 aa)
PEX2_104050Uncharacterized protein. (195 aa)
PEX2_070710Nop2p; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (733 aa)
PEX2_074080Uncharacterized protein. (109 aa)
PEX2_008020Uncharacterized protein. (679 aa)
PEX2_012690tRNA (C5-cytosine) methyltransferase, NCL1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (1165 aa)
PEX2_019880Exosome-associated factor Rrp47/DNA strand repair C1D. (428 aa)
PEX2_070470Uncharacterized protein. (419 aa)
PEX2_015330Uncharacterized protein. (235 aa)
PEX2_028380Uncharacterized protein. (361 aa)
PEX2_094600Uncharacterized protein. (346 aa)
PEX2_007230Uncharacterized protein. (506 aa)
PEX2_010500Arsenite methyltransferase. (286 aa)
PEX2_109960Uncharacterized protein. (111 aa)
PEX2_049390SAM-dependent RNA methyltransferase, predicted. (204 aa)
PEX2_047860tRNA (Guanine-N1-)-methyltransferase. (417 aa)
PEX2_060740Uncharacterized protein. (449 aa)
PEX2_057340Uncharacterized protein. (221 aa)
PEX2_039010N2227 domain-containing protein. (411 aa)
PEX2_008870Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (550 aa)
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.