90 items (Penicillium expansum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PEX2_083600	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (518 aa)
	PEX2_075300	Uncharacterized protein. (684 aa)
	PEX2_103920	Chromatin modification-related protein. (617 aa)
	PEX2_065380	Uncharacterized protein. (826 aa)
	PEX2_101310	Aminoglycoside phosphotransferase. (214 aa)
	PEX2_010090	Uncharacterized protein. (503 aa)
	PEX2_104410	Acyl-CoA N-acyltransferase. (388 aa)
	PEX2_087460	Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (825 aa)
	PEX2_087860	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (239 aa)
	PEX2_102430	WW/Rsp5/WWP; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (884 aa)
	PEX2_019800	Uncharacterized protein. (790 aa)
	PEX2_070350	Uncharacterized protein. (468 aa)
	PEX2_104370	LisH dimerization motif, subgroup. (604 aa)
	PEX2_062520	Acyl-CoA N-acyltransferase. (287 aa)
	PEX2_012720	Fibrillarin. (328 aa)
	PEX2_053530	Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2. (493 aa)
	PEX2_054580	Ubiquitin-conjugating enzyme, E2; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	PEX2_045430	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (388 aa)
	PEX2_041820	Zinc finger, PHD-finger. (970 aa)
	PEX2_100650	Sirtuin family. (565 aa)
	PEX2_004560	Non-specific serine/threonine protein kinase. (828 aa)
	PEX2_102540	Non-specific serine/threonine protein kinase. (832 aa)
	PEX2_084880	Uncharacterized protein. (118 aa)
	PEX2_082610	WD_REPEATS_REGION domain-containing protein. (517 aa)
	PEX2_038930	FAS1 domain-containing protein. (180 aa)
	PEX2_096650	Leo1-like protein. (434 aa)
	PEX2_066460	Histone deacetylase interacting. (1693 aa)
	PEX2_012380	Histone-fold. (507 aa)
	PEX2_045130	Uncharacterized protein. (376 aa)
	PEX2_047560	Tetratricopeptide-like helical. (1644 aa)
	PEX2_084630	Uncharacterized protein. (363 aa)
	PEX2_061870	Chromatin modification-related protein EAF7. (290 aa)
	PEX2_095330	Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (517 aa)
	PEX2_087010	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (505 aa)
	PEX2_097740	Uncharacterized protein. (643 aa)
	PEX2_076580	Uncharacterized protein. (414 aa)
	PEX2_097990	Uncharacterized protein. (298 aa)
	PEX2_076180	Telomere-length maintenance and DNA damage repair. (400 aa)
	PEX2_021240	Histone deacetylation protein Rxt3. (880 aa)
	PEX2_020640	Uncharacterized protein. (493 aa)
	PEX2_003980	DUF3591 domain-containing protein. (1116 aa)
	PEX2_076170	PIK-related kinase, FATC; Belongs to the PI3/PI4-kinase family. (2172 aa)
	PEX2_049510	Transcriptional regulatory protein RXT2, N-terminal. (507 aa)
	PEX2_082480	Uncharacterized protein; Belongs to the actin family. (471 aa)
	PEX2_048240	HAD_SAK_1 domain-containing protein. (576 aa)
	PEX2_005710	Histone-fold. (293 aa)
	PEX2_070960	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (765 aa)
	PEX2_029550	SET domain-containing protein. (328 aa)
	PEX2_026260	Uncharacterized protein. (422 aa)
	PEX2_018440	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (469 aa)
	PEX2_039410	JmjC domain-containing protein. (541 aa)
	PEX2_056940	Uncharacterized protein. (1406 aa)
	PEX2_057220	Myb-like domain-containing protein. (562 aa)
	PEX2_009780	Bromodomain transcription factor. (1119 aa)
	PEX2_106320	Histone deacetylase superfamily. (620 aa)
	PEX2_049270	WD_REPEATS_REGION domain-containing protein. (309 aa)
	PEX2_110610	Zinc finger, PHD-type. (1637 aa)
	PEX2_008160	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1085 aa)
	PEX2_009720	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (282 aa)
	PEX2_105800	Winged helix-turn-helix transcription repressor DNA-binding. (1093 aa)
	PEX2_036980	Acyl-CoA N-acyltransferase. (419 aa)
	PEX2_026800	Uncharacterized protein. (500 aa)
	PEX2_031810	Uncharacterized protein. (248 aa)
	PEX2_055700	Uncharacterized protein. (172 aa)
	PEX2_072170	Uncharacterized protein. (721 aa)
	PEX2_086670	WD_REPEATS_REGION domain-containing protein. (369 aa)
	PEX2_008340	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
	PEX2_081900	MRG domain-containing protein. (308 aa)
	PEX2_021770	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (503 aa)
	PEX2_061230	SGF29 C-terminal domain-containing protein. (326 aa)
	PEX2_091210	SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (297 aa)
	PEX2_051690	Concanavalin A-like lectin/glucanases superfamily. (596 aa)
	PEX2_040680	Uncharacterized protein. (352 aa)
	PEX2_001490	RNA polymerase II accessory factor, Cdc73. (474 aa)
	PEX2_036970	Uncharacterized protein. (364 aa)
	PEX2_020620	Histone H4 acetyltransferase, NuA4 complex, Eaf6. (230 aa)
	PEX2_078260	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (355 aa)
	PEX2_018910	RNA polymerase II-associated, Paf1. (486 aa)
	PEX2_077480	Zinc finger, PHD-type. (879 aa)
	PEX2_094740	Zinc finger, MYND-type. (612 aa)
	PEX2_055060	PIK-related kinase, FATC; Belongs to the PI3/PI4-kinase family. (3871 aa)
	PEX2_046710	Histone-lysine N-methyltransferase SET9. (671 aa)
	PEX2_005640	WD_REPEATS_REGION domain-containing protein. (478 aa)
	PEX2_051460	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1209 aa)
	PEX2_081070	Uncharacterized protein. (82 aa)
	PEX2_043880	Histone acetyltransferase. (533 aa)
	PEX2_025850	E3 ubiquitin protein ligase. (673 aa)
	PEX2_102570	Tetratricopeptide TPR2. (1195 aa)
	PEX2_070220	Uncharacterized protein. (709 aa)
	PEX2_099560	Uncharacterized protein. (408 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PEX2_001490	PEX2_005640	A0A0A2IR94	A0A0A2IAI8	RNA polymerase II accessory factor, Cdc73.	WD_REPEATS_REGION domain-containing protein.	0.451
PEX2_001490	PEX2_018440	A0A0A2IR94	A0A0A2JGI9	RNA polymerase II accessory factor, Cdc73.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.423
PEX2_001490	PEX2_018910	A0A0A2IR94	A0A0A2IGF1	RNA polymerase II accessory factor, Cdc73.	RNA polymerase II-associated, Paf1.	0.999
PEX2_001490	PEX2_025850	A0A0A2IR94	A0A0A2I7E4	RNA polymerase II accessory factor, Cdc73.	E3 ubiquitin protein ligase.	0.916
PEX2_001490	PEX2_031810	A0A0A2IR94	A0A0A2J4D0	RNA polymerase II accessory factor, Cdc73.	Uncharacterized protein.	0.431
PEX2_001490	PEX2_049270	A0A0A2IR94	A0A0A2JB66	RNA polymerase II accessory factor, Cdc73.	WD_REPEATS_REGION domain-containing protein.	0.999
PEX2_001490	PEX2_051460	A0A0A2IR94	A0A0A2I9Q7	RNA polymerase II accessory factor, Cdc73.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.556
PEX2_001490	PEX2_054580	A0A0A2IR94	A0A0A2K685	RNA polymerase II accessory factor, Cdc73.	Ubiquitin-conjugating enzyme, E2; Belongs to the ubiquitin-conjugating enzyme family.	0.818
PEX2_001490	PEX2_065380	A0A0A2IR94	A0A0A2L8A0	RNA polymerase II accessory factor, Cdc73.	Uncharacterized protein.	0.495
PEX2_001490	PEX2_070960	A0A0A2IR94	A0A0A2JIN8	RNA polymerase II accessory factor, Cdc73.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.657
PEX2_001490	PEX2_075300	A0A0A2IR94	A0A0A2L1M9	RNA polymerase II accessory factor, Cdc73.	Uncharacterized protein.	0.431
PEX2_001490	PEX2_082610	A0A0A2IR94	A0A0A2KBK5	RNA polymerase II accessory factor, Cdc73.	WD_REPEATS_REGION domain-containing protein.	0.431
PEX2_001490	PEX2_096650	A0A0A2IR94	A0A0A2KEJ6	RNA polymerase II accessory factor, Cdc73.	Leo1-like protein.	0.999
PEX2_001490	PEX2_102430	A0A0A2IR94	A0A0A2K0I5	RNA polymerase II accessory factor, Cdc73.	WW/Rsp5/WWP; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.591
PEX2_001490	PEX2_102570	A0A0A2IR94	A0A0A2I7E3	RNA polymerase II accessory factor, Cdc73.	Tetratricopeptide TPR2.	0.999
PEX2_001490	PEX2_106320	A0A0A2IR94	A0A0A2JBA6	RNA polymerase II accessory factor, Cdc73.	Histone deacetylase superfamily.	0.694
PEX2_003980	PEX2_005710	A0A0A2JNS8	A0A0A2JKE0	DUF3591 domain-containing protein.	Histone-fold.	0.999
PEX2_003980	PEX2_008160	A0A0A2JNS8	A0A0A2J8Q7	DUF3591 domain-containing protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.467
PEX2_003980	PEX2_009720	A0A0A2JNS8	A0A0A2J6R9	DUF3591 domain-containing protein.	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	0.815
PEX2_003980	PEX2_012380	A0A0A2JNS8	A0A0A2KF53	DUF3591 domain-containing protein.	Histone-fold.	0.622