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PEX2_033770 PEX2_033770 PEX2_099320 PEX2_099320 PEX2_012230 PEX2_012230 PEX2_103520 PEX2_103520 PEX2_028780 PEX2_028780 PEX2_036940 PEX2_036940 PEX2_100160 PEX2_100160 PEX2_006650 PEX2_006650 PEX2_036930 PEX2_036930 PEX2_038350 PEX2_038350 PEX2_079650 PEX2_079650 PEX2_028410 PEX2_028410 PEX2_008010 PEX2_008010 PEX2_050600 PEX2_050600 PEX2_104310 PEX2_104310 PEX2_095910 PEX2_095910 PEX2_095050 PEX2_095050 PEX2_013170 PEX2_013170 PEX2_082030 PEX2_082030 PEX2_059430 PEX2_059430 PEX2_024730 PEX2_024730 PEX2_061840 PEX2_061840 PEX2_033940 PEX2_033940 PEX2_038520 PEX2_038520 PEX2_023860 PEX2_023860 PEX2_008370 PEX2_008370 PEX2_059560 PEX2_059560 PEX2_107490 PEX2_107490 PEX2_032960 PEX2_032960 PEX2_073630 PEX2_073630 PEX2_055170 PEX2_055170 PEX2_099950 PEX2_099950 PEX2_021380 PEX2_021380 PEX2_101520 PEX2_101520 PEX2_013390 PEX2_013390 PEX2_103290 PEX2_103290 PEX2_050370 PEX2_050370 CIA1 CIA1 NTH1 NTH1 PEX2_058130 PEX2_058130 PEX2_097350 PEX2_097350 PEX2_061630 PEX2_061630 NBP35 NBP35 PEX2_001410 PEX2_001410 PEX2_003170 PEX2_003170 PEX2_021270 PEX2_021270 PEX2_084680 PEX2_084680 PEX2_068820 PEX2_068820 PEX2_069070 PEX2_069070 PEX2_053210 PEX2_053210 PEX2_044480 PEX2_044480 PEX2_107270 PEX2_107270 PEX2_007670 PEX2_007670 PEX2_065270 PEX2_065270 PEX2_041630 PEX2_041630 PEX2_044920 PEX2_044920 DRE2 DRE2 PEX2_047530 PEX2_047530 PEX2_078210 PEX2_078210 PEX2_017650 PEX2_017650 PEX2_044270 PEX2_044270 PEX2_046020 PEX2_046020 PEX2_042760 PEX2_042760 PEX2_013380 PEX2_013380
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PEX2_033770Glutamate synthase, central-N. (2122 aa)
PEX2_099320NADH-quinone oxidoreductase, chain I. (220 aa)
PEX2_012230Helicase-like, DEXD box c2 type. (796 aa)
PEX2_103520Iron hydrogenase; Belongs to the NARF family. (596 aa)
PEX2_028780Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha. (199 aa)
PEX2_0369402-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (569 aa)
PEX2_100160Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (781 aa)
PEX2_006650HIRA-interacting protein 5. (315 aa)
PEX2_036930Uncharacterized protein. (878 aa)
PEX2_038350Molybdenum cofactor biosynthesis protein A. (332 aa)
PEX2_079650Aminotransferase, class V/Cysteine desulfurase. (392 aa)
PEX2_028410Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (635 aa)
PEX2_008010NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (495 aa)
PEX2_050600Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (416 aa)
PEX2_104310BolA protein; Belongs to the BolA/IbaG family. (131 aa)
PEX2_095910Dihydroxy-acid/6-phosphogluconate dehydratase. (653 aa)
PEX2_095050FeS cluster insertion protein. (230 aa)
PEX2_0131702-methylcitrate dehydratase PrpD. (502 aa)
PEX2_082030Frataxin. (212 aa)
PEX2_059430Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (157 aa)
PEX2_024730Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (798 aa)
PEX2_061840Nitrite reductase [NAD(P)H] large subunit, NirD. (1083 aa)
PEX2_033940NADH-quinone oxidoreductase, chain G, C-terminal; Belongs to the complex I 75 kDa subunit family. (737 aa)
PEX2_038520Dihydroxy-acid/6-phosphogluconate dehydratase. (596 aa)
PEX2_023860Pyridine nucleotide-disulfide oxidoreductase, dimerization. (551 aa)
PEX2_008370FeS cluster insertion protein. (192 aa)
PEX2_059560NADH-ubiquinone oxidoreductase, 20 Kd subunit; Belongs to the complex I 20 kDa subunit family. (230 aa)
PEX2_107490Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (237 aa)
PEX2_032960Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II. (1527 aa)
PEX2_073630Uncharacterized protein. (366 aa)
PEX2_055170ATPase MipZ/NubP2/Cfd1. (309 aa)
PEX2_099950Dihydroxy-acid/6-phosphogluconate dehydratase. (608 aa)
PEX2_0213802-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (435 aa)
PEX2_101520ABC transporter, ABCE. (712 aa)
PEX2_013390Thioredoxin-like 2Fe-2S ferredoxin. (312 aa)
PEX2_103290Uncharacterized protein. (1669 aa)
PEX2_050370DNA polymerase. (1693 aa)
CIA1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (451 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (425 aa)
PEX2_058130Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (201 aa)
PEX2_097350BolA protein; Belongs to the BolA/IbaG family. (129 aa)
PEX2_061630Uncharacterized protein. (266 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (343 aa)
PEX2_001410Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3. (1309 aa)
PEX2_003170NAD(P)H-quinone oxidoreductase subunit D/H; Belongs to the complex I 49 kDa subunit family. (473 aa)
PEX2_021270Uncharacterized protein. (244 aa)
PEX2_084680Uncharacterized protein. (277 aa)
PEX2_068820Glutaredoxin domain-containing protein. (248 aa)
PEX2_069070Cysteine desulfurase. (507 aa)
PEX2_053210Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (783 aa)
PEX2_044480ATP-grasp fold, subdomain 1. (558 aa)
PEX2_107270Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (271 aa)
PEX2_007670FAD-binding, type 2. (1358 aa)
PEX2_065270ATPase-like, ParA/MinD. (343 aa)
PEX2_041630DNA polymerase. (1104 aa)
PEX2_044920Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (575 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (320 aa)
PEX2_047530DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (501 aa)
PEX2_078210DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2228 aa)
PEX2_017650Dihydroxy-acid/6-phosphogluconate dehydratase. (607 aa)
PEX2_044270Adrenodoxin. (202 aa)
PEX2_046020DUF3824 domain-containing protein. (873 aa)
PEX2_042760Molybdenum cofactor synthesis C-terminal. (1316 aa)
PEX2_013380Elongator protein 3/MiaB/NifB. (389 aa)
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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