node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DRE2 | PEX2_013380 | A0A0A2I8L2 | A0A0A2KCM9 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Elongator protein 3/MiaB/NifB. | 0.432 |
DRE2 | PEX2_044270 | A0A0A2I8L2 | A0A0A2K5C0 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Adrenodoxin. | 0.414 |
DRE2 | PEX2_058130 | A0A0A2I8L2 | A0A0A2JLN6 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.521 |
DRE2 | PEX2_059430 | A0A0A2I8L2 | A0A0A2JD59 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.939 |
DRE2 | PEX2_068820 | A0A0A2I8L2 | A0A0A2JSF3 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Glutaredoxin domain-containing protein. | 0.951 |
DRE2 | PEX2_082030 | A0A0A2I8L2 | A0A0A2JCM7 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Frataxin. | 0.457 |
DRE2 | PEX2_097350 | A0A0A2I8L2 | A0A0A2JME5 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | BolA protein; Belongs to the BolA/IbaG family. | 0.757 |
DRE2 | PEX2_104310 | A0A0A2I8L2 | A0A0A2J562 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | BolA protein; Belongs to the BolA/IbaG family. | 0.757 |
PEX2_008370 | PEX2_013380 | A0A0A2JHE4 | A0A0A2KCM9 | FeS cluster insertion protein. | Elongator protein 3/MiaB/NifB. | 0.438 |
PEX2_008370 | PEX2_021270 | A0A0A2JHE4 | A0A0A2JQN0 | FeS cluster insertion protein. | Uncharacterized protein. | 0.419 |
PEX2_008370 | PEX2_044270 | A0A0A2JHE4 | A0A0A2K5C0 | FeS cluster insertion protein. | Adrenodoxin. | 0.747 |
PEX2_008370 | PEX2_058130 | A0A0A2JHE4 | A0A0A2JLN6 | FeS cluster insertion protein. | Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.873 |
PEX2_008370 | PEX2_059430 | A0A0A2JHE4 | A0A0A2JD59 | FeS cluster insertion protein. | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.851 |
PEX2_008370 | PEX2_061630 | A0A0A2JHE4 | A0A0A2JMN6 | FeS cluster insertion protein. | Uncharacterized protein. | 0.824 |
PEX2_008370 | PEX2_068820 | A0A0A2JHE4 | A0A0A2JSF3 | FeS cluster insertion protein. | Glutaredoxin domain-containing protein. | 0.859 |
PEX2_008370 | PEX2_073630 | A0A0A2JHE4 | A0A0A2JXM3 | FeS cluster insertion protein. | Uncharacterized protein. | 0.824 |
PEX2_008370 | PEX2_082030 | A0A0A2JHE4 | A0A0A2JCM7 | FeS cluster insertion protein. | Frataxin. | 0.560 |
PEX2_008370 | PEX2_084680 | A0A0A2JHE4 | A0A0A2JRJ9 | FeS cluster insertion protein. | Uncharacterized protein. | 0.824 |
PEX2_008370 | PEX2_095050 | A0A0A2JHE4 | A0A0A2J6T3 | FeS cluster insertion protein. | FeS cluster insertion protein. | 0.994 |
PEX2_008370 | PEX2_097350 | A0A0A2JHE4 | A0A0A2JME5 | FeS cluster insertion protein. | BolA protein; Belongs to the BolA/IbaG family. | 0.407 |