(54 nodes) Intrinsic component of mitochondrial membrane network (Penicillium expansum)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	PEX2_028410	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (635 aa)
	PEX2_034670	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (119 aa)
	PEX2_060930	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (91 aa)
	PEX2_002500	Cytochrome c oxidase assembly protein PET191. (118 aa)
	PEX2_098170	Membrane insertase OXA1/ALB3/YidC. (501 aa)
	PEX2_068380	Transcription factor, fungi. (640 aa)
	PEX2_098180	Outer membrane protein, MIM1/TOM13, mitochondrial. (130 aa)
	PEX2_014480	Uncharacterized protein. (56 aa)
	PEX2_004010	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (252 aa)
	PEX2_088960	Tafazzin family protein; Belongs to the taffazin family. (263 aa)
	PSD1	Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (543 aa)
	PEX2_037080	ATPase, AAA-type, core. (914 aa)
	PEX2_039970	L-gulonolactone/D-arabinono-1,4-lactone oxidase. (584 aa)
	PEX2_033740	Mitochondrial escape protein 2. (792 aa)
	PEX2_030320	Uncharacterized protein. (202 aa)
	PEX2_011140	Protein import receptor MAS20-like protein. (164 aa)
	PEX2_094240	Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24. (154 aa)
	PEX2_100600	ATPase assembly factor ATP10, mitochondria. (353 aa)
	PEX2_064750	Coiled-coil domain containing protein 109, C-terminal. (360 aa)
	PEX2_048220	FAD linked oxidase, N-terminal. (480 aa)
	PEX2_106450	Bax inhibitor 1-like protein; Belongs to the BI1 family. (336 aa)
	PEX2_027000	N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D. (398 aa)
	PEX2_028160	FAD linked oxidase, N-terminal. (496 aa)
	PEX2_009630	Regulator of chromosome condensation, RCC1. (571 aa)
	PEX2_059410	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (418 aa)
	PEX2_061600	Uncharacterized protein. (275 aa)
	PEX2_058140	ABC1 domain-containing protein. (622 aa)
	PEX2_060150	HIG1 domain-containing protein. (277 aa)
	PEX2_039130	Mitochondrial carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
	PEX2_039580	Uncharacterized protein. (475 aa)
	PEX2_059380	Cytochrome oxidase assembly protein 1. (183 aa)
	PEX2_024800	Membrane insertase OXA1/ALB3/YidC. (181 aa)
	PEX2_089220	Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24. (204 aa)
	PEX2_021670	Mitochondrial substrate/solute carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
	PEX2_002350	Uncharacterized protein. (181 aa)
	PEX2_014720	EF hand associated, type-1. (1187 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (549 aa)
	MDM10	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (486 aa)
	PEX2_044280	Uncharacterized protein. (500 aa)
	PEX2_075560	MICOS complex subunit MIC12; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (125 aa)
	PEX2_082600	Endonuclease/exonuclease/phosphatase. (496 aa)
	PEX2_021520	Cytochrome c oxidase assembly protein CtaG/Cox11. (252 aa)
	PEX2_109300	Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24. (154 aa)
	PEX2_017550	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (179 aa)
	PEX2_043020	Sidoreflexin. (339 aa)
	PEX2_005100	HIG1 domain-containing protein. (97 aa)
	PEX2_045410	Ubiquinol-cytochrome c chaperone, CBP3. (302 aa)
	PEX2_015160	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (923 aa)
	PEX2_025440	Uncharacterized protein. (101 aa)
	PEX2_085490	Mitochondrial outer membrane translocase complex, subunit Tom70. (622 aa)
	PEX2_000200	Heat shock protein DnaJ, N-terminal. (766 aa)
	PEX2_078870	Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (916 aa)
	PEX2_020200	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (499 aa)
	PEX2_050880	Uncharacterized protein. (125 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MDM10	MDM34	A0A0A2KP65	A0A0A2KTJ3	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.988
MDM10	PEX2_011140	A0A0A2KP65	A0A0A2I5G6	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Protein import receptor MAS20-like protein.	0.610
MDM10	PEX2_014720	A0A0A2KP65	A0A0A2KYI9	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	EF hand associated, type-1.	0.688
MDM10	PEX2_015160	A0A0A2KP65	A0A0A2K281	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.543
MDM10	PEX2_058140	A0A0A2KP65	A0A0A2JEJ7	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	ABC1 domain-containing protein.	0.404
MDM10	PEX2_078870	A0A0A2KP65	A0A0A2JVQ6	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.674
MDM10	PEX2_085490	A0A0A2KP65	A0A0A2K196	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Mitochondrial outer membrane translocase complex, subunit Tom70.	0.514
MDM10	PEX2_098180	A0A0A2KP65	A0A0A2INF9	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Outer membrane protein, MIM1/TOM13, mitochondrial.	0.431
MDM34	MDM10	A0A0A2KTJ3	A0A0A2KP65	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	0.988
MDM34	PEX2_011140	A0A0A2KTJ3	A0A0A2I5G6	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Protein import receptor MAS20-like protein.	0.512
MDM34	PEX2_014720	A0A0A2KTJ3	A0A0A2KYI9	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	EF hand associated, type-1.	0.687
MDM34	PEX2_015160	A0A0A2KTJ3	A0A0A2K281	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.673
MDM34	PEX2_078870	A0A0A2KTJ3	A0A0A2JVQ6	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.679
MDM34	PSD1	A0A0A2KTJ3	A0A0A2IEN7	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.	0.412
PEX2_000200	PEX2_014720	A0A0A2JYT1	A0A0A2KYI9	Heat shock protein DnaJ, N-terminal.	EF hand associated, type-1.	0.412
PEX2_000200	PEX2_060930	A0A0A2JYT1	A0A0A2IUF5	Heat shock protein DnaJ, N-terminal.	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.607
PEX2_002350	PEX2_098180	A0A0A2JR12	A0A0A2INF9	Uncharacterized protein.	Outer membrane protein, MIM1/TOM13, mitochondrial.	0.431
PEX2_002500	PEX2_021520	A0A0A2ISN4	A0A0A2K783	Cytochrome c oxidase assembly protein PET191.	Cytochrome c oxidase assembly protein CtaG/Cox11.	0.482
PEX2_004010	PEX2_060930	A0A0A2IKD0	A0A0A2IUF5	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.945
PEX2_011140	MDM10	A0A0A2I5G6	A0A0A2KP65	Protein import receptor MAS20-like protein.	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	0.610