76 items (Penicillium expansum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PEX2_020040	Mediator complex, subunit Med12. (1570 aa)
	PEX2_103900	Uncharacterized protein. (642 aa)
	PEX2_069220	Chromatin associated protein KTI12. (418 aa)
	PEX2_005630	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1738 aa)
	PEX2_023480	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (351 aa)
	PEX2_097190	Uncharacterized protein. (234 aa)
	PEX2_097070	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (657 aa)
	PEX2_103510	RNA polymerase archaeal subunit P/eukaryotic subunit RPC10. (78 aa)
	PEX2_078050	DNA-directed RNA polymerase I, subunit RPA34.5. (313 aa)
	PEX2_098890	Uncharacterized protein. (649 aa)
	PEX2_100590	DNA polymerase family X. (713 aa)
	PEX2_026120	RNA_pol_L_2 domain-containing protein. (138 aa)
	PEX2_096650	Leo1-like protein. (434 aa)
	PEX2_023540	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1255 aa)
	PEX2_032730	Transcription initiation factor IIA, gamma subunit. (496 aa)
	PEX2_003180	DNA-directed RNA polymerase, dimerization. (374 aa)
	PEX2_088170	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (143 aa)
	PEX2_046590	Acyltransferase 3. (481 aa)
	PEX2_018500	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1208 aa)
	PEX2_005540	Transcription factor IIA, alpha/beta subunit. (372 aa)
	PEX2_019200	DNA polymerase. (1461 aa)
	PEX2_085190	Plus-3. (611 aa)
	PEX2_066550	Transcription initiation factor IIF, beta subunit. (363 aa)
	PEX2_093480	DNA-directed RNA polymerase, dimerization. (335 aa)
	PEX2_033900	Ssl1 domain-containing protein. (232 aa)
	PEX2_088740	Uncharacterized protein. (640 aa)
	PEX2_019640	Histone-fold. (616 aa)
	PEX2_075630	Histone-fold. (389 aa)
	PEX2_007180	Cdk-activating kinase assembly factor MAT1, centre. (352 aa)
	PEX2_102570	Tetratricopeptide TPR2. (1195 aa)
	PEX2_012650	DNA-directed RNA polymerase, RPB5 subunit. (234 aa)
	PEX2_084820	RNA polymerase III Rpc4. (579 aa)
	PEX2_051590	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (692 aa)
	PEX2_012190	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1671 aa)
	PEX2_046370	Transcription factor TFIIE, alpha subunit. (450 aa)
	PEX2_047530	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (501 aa)
	PEX2_046730	DNA-directed RNA polymerase, M/15kDa subunit. (136 aa)
	PEX2_075550	Uncharacterized protein. (294 aa)
	PEX2_016890	TFIID subunit, WD40-associated region. (751 aa)
	PEX2_018910	RNA polymerase II-associated, Paf1. (486 aa)
	PEX2_027080	Acyltransferase 3. (457 aa)
	PEX2_088750	DNA-directed RNA polymerase, subunit N/Rpb10. (74 aa)
	PEX2_024010	Uncharacterized protein. (292 aa)
	PEX2_032920	DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1284 aa)
	PEX2_020830	RNA polymerase II, Rpb4, core. (148 aa)
	PEX2_098900	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (241 aa)
	PEX2_098130	TATA box binding protein associated factor (TAF). (442 aa)
	PEX2_098160	Acyltransferase 3. (473 aa)
	PEX2_001490	RNA polymerase II accessory factor, Cdc73. (474 aa)
	PEX2_070290	RNA polymerase III, subunit Rpc25. (193 aa)
	PEX2_044590	Uncharacterized protein. (567 aa)
	PEX2_027890	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (293 aa)
	PEX2_094450	Uncharacterized protein. (291 aa)
	PEX2_049270	WD_REPEATS_REGION domain-containing protein. (309 aa)
	PEX2_082500	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1249 aa)
	PEX2_028550	DUF4211 domain-containing protein. (654 aa)
	PEX2_048150	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (505 aa)
	PEX2_024830	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (116 aa)
	PEX2_110520	RNA polymerase, subunit omega/K/RPABC2. (153 aa)
	PEX2_005710	Histone-fold. (293 aa)
	PEX2_087740	Transcription factor Tfb4. (379 aa)
	PEX2_047690	Uncharacterized protein. (615 aa)
	PEX2_035240	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (479 aa)
	PEX2_023870	RNA polymerase Rpb7, N-terminal. (385 aa)
	PEX2_003980	DUF3591 domain-containing protein. (1116 aa)
	PEX2_098150	Histone-fold. (397 aa)
	PEX2_019460	RNA polymerase II-associated protein 1, N-terminal. (457 aa)
	PEX2_038130	Uncharacterized protein. (1243 aa)
	PEX2_040100	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
	PEX2_067990	Bromodomain transcription factor. (215 aa)
	PEX2_093720	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (641 aa)
	PEX2_032930	DNA-directed RNA polymerase III subunit Rpc5. (322 aa)
	PEX2_087860	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (239 aa)
	PEX2_000550	Helicase, C-terminal. (822 aa)
	PEX2_067980	TAFII55 protein, conserved region. (474 aa)
	PEX2_040560	Uncharacterized protein. (837 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PEX2_000550	PEX2_003180	A0A0A2JYV8	A0A0A2K998	Helicase, C-terminal.	DNA-directed RNA polymerase, dimerization.	0.962
PEX2_000550	PEX2_003980	A0A0A2JYV8	A0A0A2JNS8	Helicase, C-terminal.	DUF3591 domain-containing protein.	0.864
PEX2_000550	PEX2_005540	A0A0A2JYV8	A0A0A2K4R1	Helicase, C-terminal.	Transcription factor IIA, alpha/beta subunit.	0.975
PEX2_000550	PEX2_005630	A0A0A2JYV8	A0A0A2L1S1	Helicase, C-terminal.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.988
PEX2_000550	PEX2_005710	A0A0A2JYV8	A0A0A2JKE0	Helicase, C-terminal.	Histone-fold.	0.864
PEX2_000550	PEX2_007180	A0A0A2JYV8	A0A0A2I749	Helicase, C-terminal.	Cdk-activating kinase assembly factor MAT1, centre.	0.996
PEX2_000550	PEX2_012190	A0A0A2JYV8	A0A0A2I945	Helicase, C-terminal.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.798
PEX2_000550	PEX2_012650	A0A0A2JYV8	A0A0A2I7F3	Helicase, C-terminal.	DNA-directed RNA polymerase, RPB5 subunit.	0.984
PEX2_000550	PEX2_016890	A0A0A2JYV8	A0A0A2IDX5	Helicase, C-terminal.	TFIID subunit, WD40-associated region.	0.864
PEX2_000550	PEX2_018500	A0A0A2JYV8	A0A0A2K6G1	Helicase, C-terminal.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.953
PEX2_000550	PEX2_019200	A0A0A2JYV8	A0A0A2K3I5	Helicase, C-terminal.	DNA polymerase.	0.440
PEX2_000550	PEX2_019640	A0A0A2JYV8	A0A0A2I4D0	Helicase, C-terminal.	Histone-fold.	0.875
PEX2_000550	PEX2_020830	A0A0A2JYV8	A0A0A2INM0	Helicase, C-terminal.	RNA polymerase II, Rpb4, core.	0.975
PEX2_000550	PEX2_023540	A0A0A2JYV8	A0A0A2KBK9	Helicase, C-terminal.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.976
PEX2_000550	PEX2_024830	A0A0A2JYV8	A0A0A2JF51	Helicase, C-terminal.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.884
PEX2_000550	PEX2_026120	A0A0A2JYV8	A0A0A2KHB2	Helicase, C-terminal.	RNA_pol_L_2 domain-containing protein.	0.447
PEX2_000550	PEX2_027080	A0A0A2JYV8	A0A0A2IHR8	Helicase, C-terminal.	Acyltransferase 3.	0.838
PEX2_000550	PEX2_027890	A0A0A2JYV8	A0A0A2J4H9	Helicase, C-terminal.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.996
PEX2_000550	PEX2_028550	A0A0A2JYV8	A0A0A2JD98	Helicase, C-terminal.	DUF4211 domain-containing protein.	0.843
PEX2_000550	PEX2_032730	A0A0A2JYV8	A0A0A2KAL5	Helicase, C-terminal.	Transcription initiation factor IIA, gamma subunit.	0.969