(90 nodes) Armadillo-like helical network (Penicillium expansum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PEX2_045890	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (2899 aa)
	PEX2_033240	Uncharacterized protein. (590 aa)
	PEX2_047240	Armadillo-like helical. (1146 aa)
	PEX2_084700	SCD domain-containing protein. (1178 aa)
	PEX2_010940	HEAT, type 2. (1572 aa)
	PEX2_049040	Engulfment/cell motility, ELMO. (698 aa)
	PEX2_026270	Armadillo-like helical. (215 aa)
	PEX2_100560	PUM-HD domain-containing protein. (695 aa)
	PEX2_038940	Transcription protein MMS19, N-terminal. (1083 aa)
	PEX2_036200	HEAT, type 2. (615 aa)
	PEX2_102210	Armadillo-like helical. (970 aa)
	PEX2_060880	Cell division protein Cdc14. (286 aa)
	PEX2_012640	Armadillo-like helical. (296 aa)
	PEX2_062860	26S proteasome regulatory subunit RPN2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1129 aa)
	PEX2_077760	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (917 aa)
	PEX2_008860	Armadillo-like helical. (383 aa)
	PEX2_009620	Armadillo-like helical. (726 aa)
	PEX2_051580	Oligopeptide transporter OPT superfamily. (1373 aa)
	PEX2_059100	Armadillo-like helical. (903 aa)
	PEX2_083640	Sister chromatid cohesion protein. (1779 aa)
	PEX2_035180	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (945 aa)
	PEX2_012030	Armadillo-like helical. (1148 aa)
	PEX2_072900	Uncharacterized protein. (785 aa)
	PEX2_022200	Putative domain NUC173. (1259 aa)
	PEX2_025550	Armadillo-like helical. (904 aa)
	PEX2_022580	Armadillo-like helical. (1117 aa)
	LIA1	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. (330 aa)
	PEX2_032000	Armadillo. (995 aa)
	PEX2_103050	Uncharacterized protein. (388 aa)
	PEX2_027350	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (955 aa)
	PEX2_095080	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (739 aa)
	PEX2_095800	Helicase, C-terminal. (1897 aa)
	PEX2_095020	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2820 aa)
	PEX2_065180	HEAT, type 2. (1090 aa)
	PEX2_051130	Proteasome stabiliser ECM29. (1858 aa)
	PEX2_047880	Armadillo-like helical. (1256 aa)
	PEX2_058150	Armadillo-like helical. (1342 aa)
	PEX2_084320	Down-regulated-in-metastasis protein. (2627 aa)
	PEX2_061970	HEAT, type 2. (1317 aa)
	PEX2_063430	Armadillo-like helical. (443 aa)
	PEX2_095470	Armadillo-like helical. (1095 aa)
	PEX2_084740	Importin subunit alpha; Belongs to the importin alpha family. (552 aa)
	PEX2_088050	AP complex subunit beta. (842 aa)
	PEX2_045030	HEAT, type 2. (1067 aa)
	PEX2_099520	Guanine nucleotide exchange factor, Ric8. (466 aa)
	PEX2_053960	HEAT, type 2. (1804 aa)
	PEX2_081200	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1073 aa)
	PEX2_025480	CAS/CSE, C-terminal. (959 aa)
	PEX2_041710	Uncharacterized protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (1125 aa)
	PEX2_074630	Armadillo-like helical. (778 aa)
	PEX2_087380	26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (903 aa)
	PEX2_008080	Diaphanous GTPase-binding. (860 aa)
	PEX2_019320	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1216 aa)
	PEX2_019410	Interferon-related developmental regulator, N-terminal. (482 aa)
	PEX2_019480	Anaphase-promoting complex subunit 1. (2058 aa)
	PEX2_073160	Armadillo-like helical. (1010 aa)
	PEX2_041860	Armadillo-like helical. (1490 aa)
	PEX2_025340	Armadillo-like helical. (2054 aa)
	PEX2_023560	DUF1716 domain-containing protein. (583 aa)
	PEX2_018510	Armadillo-like helical. (1019 aa)
	PEX2_049140	Armadillo-like helical. (1072 aa)
	PEX2_083410	Major facilitator superfamily domain, general substrate transporter; Belongs to the MT-A70-like family. (2125 aa)
	PEX2_077810	Armadillo-like helical. (1452 aa)
	PEX2_094670	Armadillo-like helical. (1050 aa)
	PEX2_006210	Armadillo-like helical. (1038 aa)
	PEX2_059640	Wings apart-like protein. (857 aa)
	PEX2_030330	Armadillo-like helical. (303 aa)
	PEX2_039620	Armadillo-like helical. (869 aa)
	PEX2_039790	Armadillo-like helical. (939 aa)
	PEX2_029900	TATA-binding protein interacting (TIP20). (1035 aa)
	PEX2_053280	Vacuole morphology and inheritance protein 14. (947 aa)
	PEX2_087730	UNC-45/Ring assembly protein 3. (837 aa)
	PEX2_003270	Splicing factor 3B subunit 1. (1210 aa)
	PEX2_071330	Armadillo-like helical. (1142 aa)
	PEX2_095590	AP-1 complex subunit gamma. (848 aa)
	PEX2_089210	Armadillo-like helical. (1631 aa)
	PEX2_070170	DUF3453 domain-containing protein. (742 aa)
	PEX2_040040	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (918 aa)
	PEX2_092390	HECT domain-containing protein. (1796 aa)
	PEX2_048060	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (742 aa)
	PEX2_091860	Armadillo-like helical. (953 aa)
	PEX2_052580	Armadillo-like helical. (702 aa)
	PEX2_033510	Vacuolar protein 8. (578 aa)
	PEX2_054970	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (678 aa)
	PEX2_053160	Armadillo-like helical. (902 aa)
	PEX2_052340	PIK-related kinase, FATC; Belongs to the PI3/PI4-kinase family. (1956 aa)
	PEX2_100920	ATPase, V1 complex, subunit H, C-terminal. (928 aa)
	PEX2_099900	Armadillo-like helical. (1052 aa)
	PEX2_087180	Tubulin-specific chaperone D, C-terminal. (1225 aa)
	PEX2_033920	Armadillo-like helical. (820 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LIA1	PEX2_022580	A0A0A2IKN5	A0A0A2J272	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.	Armadillo-like helical.	0.804
LIA1	PEX2_045030	A0A0A2IKN5	A0A0A2K1G9	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.	HEAT, type 2.	0.725
LIA1	PEX2_053960	A0A0A2IKN5	A0A0A2K2E9	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.	HEAT, type 2.	0.445
PEX2_003270	PEX2_023560	A0A0A2JQN9	A0A0A2JGM2	Splicing factor 3B subunit 1.	DUF1716 domain-containing protein.	0.698
PEX2_003270	PEX2_083640	A0A0A2JQN9	A0A0A2ITZ0	Splicing factor 3B subunit 1.	Sister chromatid cohesion protein.	0.592
PEX2_006210	PEX2_025480	A0A0A2IF21	A0A0A2K3D0	Armadillo-like helical.	CAS/CSE, C-terminal.	0.453
PEX2_006210	PEX2_039620	A0A0A2IF21	A0A0A2I8M3	Armadillo-like helical.	Armadillo-like helical.	0.645
PEX2_006210	PEX2_039790	A0A0A2IF21	A0A0A2I8K9	Armadillo-like helical.	Armadillo-like helical.	0.666
PEX2_006210	PEX2_047880	A0A0A2IF21	A0A0A2JBZ8	Armadillo-like helical.	Armadillo-like helical.	0.524
PEX2_006210	PEX2_049140	A0A0A2IF21	A0A0A2JJU2	Armadillo-like helical.	Armadillo-like helical.	0.495
PEX2_006210	PEX2_065180	A0A0A2IF21	A0A0A2J9C9	Armadillo-like helical.	HEAT, type 2.	0.667
PEX2_006210	PEX2_073160	A0A0A2IF21	A0A0A2HYG3	Armadillo-like helical.	Armadillo-like helical.	0.521
PEX2_006210	PEX2_081200	A0A0A2IF21	A0A0A2K2I4	Armadillo-like helical.	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.	0.436
PEX2_006210	PEX2_084740	A0A0A2IF21	A0A0A2K0R8	Armadillo-like helical.	Importin subunit alpha; Belongs to the importin alpha family.	0.565
PEX2_006210	PEX2_094670	A0A0A2IF21	A0A0A2IG53	Armadillo-like helical.	Armadillo-like helical.	0.650
PEX2_006210	PEX2_095470	A0A0A2IF21	A0A0A2JEY7	Armadillo-like helical.	Armadillo-like helical.	0.666
PEX2_006210	PEX2_099900	A0A0A2IF21	A0A0A2JZV8	Armadillo-like helical.	Armadillo-like helical.	0.517
PEX2_006210	PEX2_102210	A0A0A2IF21	A0A0A2KMI2	Armadillo-like helical.	Armadillo-like helical.	0.482
PEX2_008860	PEX2_092390	A0A0A2L1K0	A0A0A2JTY4	Armadillo-like helical.	HECT domain-containing protein.	0.595
PEX2_009620	PEX2_022200	A0A0A2IMT0	A0A0A2J0N0	Armadillo-like helical.	Putative domain NUC173.	0.781