STRINGSTRING
PEX2_008340 PEX2_008340 PEX2_025850 PEX2_025850 PEX2_051460 PEX2_051460 PEX2_037310 PEX2_037310 PEX2_023490 PEX2_023490 PEX2_077350 PEX2_077350 PEX2_070960 PEX2_070960 PEX2_087010 PEX2_087010 PEX2_032220 PEX2_032220 PEX2_018440 PEX2_018440 PEX2_103920 PEX2_103920
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PEX2_008340RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
PEX2_025850E3 ubiquitin protein ligase. (673 aa)
PEX2_051460Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1209 aa)
PEX2_037310Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (505 aa)
PEX2_023490Chromatin modification-related protein. (416 aa)
PEX2_077350Chromatin modification-related protein. (678 aa)
PEX2_070960Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (765 aa)
PEX2_087010Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (505 aa)
PEX2_032220Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1063 aa)
PEX2_018440RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (469 aa)
PEX2_103920Chromatin modification-related protein. (617 aa)
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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