29 items (Penicillium expansum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PEX2_069980	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (120 aa)
	PEX2_103900	Uncharacterized protein. (642 aa)
	PEX2_005630	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1738 aa)
	PEX2_103510	RNA polymerase archaeal subunit P/eukaryotic subunit RPC10. (78 aa)
	PEX2_038860	Nucleic acid-binding, OB-fold. (169 aa)
	PEX2_023540	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1255 aa)
	PEX2_088170	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (143 aa)
	PEX2_046780	Nuclear cap-binding protein subunit 2. (190 aa)
	PEX2_000550	Helicase, C-terminal. (822 aa)
	PEX2_074030	MIF4-like, type 1/2/3. (822 aa)
	PEX2_040100	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
	PEX2_035240	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (479 aa)
	PEX2_087740	Transcription factor Tfb4. (379 aa)
	PEX2_110520	RNA polymerase, subunit omega/K/RPABC2. (153 aa)
	PEX2_062890	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1025 aa)
	PEX2_038850	Uncharacterized protein. (541 aa)
	PEX2_103390	Tetratricopeptide-like helical. (395 aa)
	PEX2_020830	RNA polymerase II, Rpb4, core. (148 aa)
	PEX2_088750	DNA-directed RNA polymerase, subunit N/Rpb10. (74 aa)
	PEX2_046730	DNA-directed RNA polymerase, M/15kDa subunit. (136 aa)
	PEX2_051590	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (692 aa)
	PEX2_012650	DNA-directed RNA polymerase, RPB5 subunit. (234 aa)
	PEX2_012230	Helicase-like, DEXD box c2 type. (796 aa)
	PEX2_007180	Cdk-activating kinase assembly factor MAT1, centre. (352 aa)
	PEX2_088740	Uncharacterized protein. (640 aa)
	PEX2_009270	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (816 aa)
	PEX2_033900	Ssl1 domain-containing protein. (232 aa)
	PEX2_093480	DNA-directed RNA polymerase, dimerization. (335 aa)
	PEX2_066550	Transcription initiation factor IIF, beta subunit. (363 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PEX2_000550	PEX2_005630	A0A0A2JYV8	A0A0A2L1S1	Helicase, C-terminal.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.988
PEX2_000550	PEX2_007180	A0A0A2JYV8	A0A0A2I749	Helicase, C-terminal.	Cdk-activating kinase assembly factor MAT1, centre.	0.996
PEX2_000550	PEX2_012230	A0A0A2JYV8	A0A0A2I779	Helicase, C-terminal.	Helicase-like, DEXD box c2 type.	0.999
PEX2_000550	PEX2_012650	A0A0A2JYV8	A0A0A2I7F3	Helicase, C-terminal.	DNA-directed RNA polymerase, RPB5 subunit.	0.984
PEX2_000550	PEX2_020830	A0A0A2JYV8	A0A0A2INM0	Helicase, C-terminal.	RNA polymerase II, Rpb4, core.	0.975
PEX2_000550	PEX2_023540	A0A0A2JYV8	A0A0A2KBK9	Helicase, C-terminal.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.976
PEX2_000550	PEX2_033900	A0A0A2JYV8	A0A0A2I0G9	Helicase, C-terminal.	Ssl1 domain-containing protein.	0.999
PEX2_000550	PEX2_035240	A0A0A2JYV8	A0A0A2JLB3	Helicase, C-terminal.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.999
PEX2_000550	PEX2_038850	A0A0A2JYV8	A0A0A2JG55	Helicase, C-terminal.	Uncharacterized protein.	0.945
PEX2_000550	PEX2_038860	A0A0A2JYV8	A0A0A2KCD2	Helicase, C-terminal.	Nucleic acid-binding, OB-fold.	0.969
PEX2_000550	PEX2_040100	A0A0A2JYV8	A0A0A2JR15	Helicase, C-terminal.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.983
PEX2_000550	PEX2_046730	A0A0A2JYV8	A0A0A2IB69	Helicase, C-terminal.	DNA-directed RNA polymerase, M/15kDa subunit.	0.973
PEX2_000550	PEX2_051590	A0A0A2JYV8	A0A0A2I7X0	Helicase, C-terminal.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.977
PEX2_000550	PEX2_066550	A0A0A2JYV8	A0A0A2HZK4	Helicase, C-terminal.	Transcription initiation factor IIF, beta subunit.	0.981
PEX2_000550	PEX2_069980	A0A0A2JYV8	A0A0A2KGX7	Helicase, C-terminal.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.709
PEX2_000550	PEX2_074030	A0A0A2JYV8	A0A0A2JUZ3	Helicase, C-terminal.	MIF4-like, type 1/2/3.	0.701
PEX2_000550	PEX2_087740	A0A0A2JYV8	A0A0A2JKJ6	Helicase, C-terminal.	Transcription factor Tfb4.	0.999
PEX2_000550	PEX2_088170	A0A0A2JYV8	A0A0A2K8D7	Helicase, C-terminal.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.970
PEX2_000550	PEX2_088740	A0A0A2JYV8	A0A0A2I2H4	Helicase, C-terminal.	Uncharacterized protein.	0.943
PEX2_000550	PEX2_088750	A0A0A2JYV8	A0A0A2IHT3	Helicase, C-terminal.	DNA-directed RNA polymerase, subunit N/Rpb10.	0.943