29 items (Penicillium expansum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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Your Input:
	PEX2_087290	Protein kinase domain-containing protein. (793 aa)
	PEX2_086140	Uncharacterized protein. (355 aa)
	PEX2_009830	Uncharacterized protein. (197 aa)
	SLX1	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (401 aa)
	PEX2_037050	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (628 aa)
	PEX2_026610	XPG N-terminal. (875 aa)
	PEX2_096280	DNA-directed DNA polymerase, family X, beta-like, N-terminal. (589 aa)
	PEX2_008400	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (413 aa)
	PEX2_009450	Ribosomal protein S27a. (193 aa)
	PEX2_047910	DUF1767 domain-containing protein. (243 aa)
	PEX2_108620	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (1107 aa)
	PEX2_059080	BZIP domain-containing protein. (250 aa)
	PEX2_061050	EthD domain-containing protein. (155 aa)
	PEX2_083470	Nucleic acid-binding, OB-fold. (536 aa)
	PEX2_057540	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (510 aa)
	PEX2_029700	DNA polymerase delta, subunit 4. (183 aa)
	PEX2_075920	Protein kinase domain-containing protein. (311 aa)
	PEX2_015670	3'-5' exonuclease domain-containing protein. (1435 aa)
	PEX2_014080	Helicase, C-terminal. (1417 aa)
	PEX2_041660	DNA polymerase subunit Cdc27. (440 aa)
	PEX2_102110	DNA recombination and repair protein Rad51, C-terminal. (390 aa)
	PEX2_020850	Zinc finger, GRF-type. (338 aa)
	PEX2_101650	DNA recombination/repair protein RecA, monomer-monomer interface; Belongs to the RecA family. (637 aa)
	PEX2_097000	ERCC4 domain-containing protein. (654 aa)
	PEX2_069000	Bromodomain transcription factor. (776 aa)
	PEX2_015370	Zinc finger, RING-type. (204 aa)
	PEX2_027860	Calcium/calmodulin-dependent/calcium-dependent protein kinase. (534 aa)
	PEX2_102470	Protein kinase domain-containing protein. (552 aa)
	PEX2_043200	DNA recombination and repair protein Rad51, C-terminal. (527 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PEX2_008400	PEX2_101650	A0A0A2J9E8	A0A0A2KTZ6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DNA recombination/repair protein RecA, monomer-monomer interface; Belongs to the RecA family.	0.739
PEX2_008400	PEX2_102110	A0A0A2J9E8	A0A0A2L2I3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DNA recombination and repair protein Rad51, C-terminal.	0.415
PEX2_009450	PEX2_009830	A0A0A2J9P5	A0A0A2I178	Ribosomal protein S27a.	Uncharacterized protein.	0.577
PEX2_009450	PEX2_014080	A0A0A2J9P5	A0A0A2K2F2	Ribosomal protein S27a.	Helicase, C-terminal.	0.547
PEX2_009450	PEX2_015370	A0A0A2J9P5	A0A0A2K4M4	Ribosomal protein S27a.	Zinc finger, RING-type.	0.823
PEX2_009450	PEX2_015670	A0A0A2J9P5	A0A0A2K1V3	Ribosomal protein S27a.	3'-5' exonuclease domain-containing protein.	0.982
PEX2_009450	PEX2_043200	A0A0A2J9P5	A0A0A2K5H0	Ribosomal protein S27a.	DNA recombination and repair protein Rad51, C-terminal.	0.663
PEX2_009450	PEX2_047910	A0A0A2J9P5	A0A0A2JBS9	Ribosomal protein S27a.	DUF1767 domain-containing protein.	0.655
PEX2_009450	PEX2_057540	A0A0A2J9P5	A0A0A2JEA1	Ribosomal protein S27a.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.547
PEX2_009450	PEX2_061050	A0A0A2J9P5	A0A0A2JDJ9	Ribosomal protein S27a.	EthD domain-containing protein.	0.547
PEX2_009450	PEX2_069000	A0A0A2J9P5	A0A0A2KJ07	Ribosomal protein S27a.	Bromodomain transcription factor.	0.582
PEX2_009450	PEX2_083470	A0A0A2J9P5	A0A0A2JDT0	Ribosomal protein S27a.	Nucleic acid-binding, OB-fold.	0.577
PEX2_009450	PEX2_096280	A0A0A2J9P5	A0A0A2J8S4	Ribosomal protein S27a.	DNA-directed DNA polymerase, family X, beta-like, N-terminal.	0.691
PEX2_009450	PEX2_101650	A0A0A2J9P5	A0A0A2KTZ6	Ribosomal protein S27a.	DNA recombination/repair protein RecA, monomer-monomer interface; Belongs to the RecA family.	0.663
PEX2_009450	PEX2_102110	A0A0A2J9P5	A0A0A2L2I3	Ribosomal protein S27a.	DNA recombination and repair protein Rad51, C-terminal.	0.536
PEX2_009450	PEX2_108620	A0A0A2J9P5	A0A0A2JC73	Ribosomal protein S27a.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.665
PEX2_009830	PEX2_009450	A0A0A2I178	A0A0A2J9P5	Uncharacterized protein.	Ribosomal protein S27a.	0.577
PEX2_009830	PEX2_014080	A0A0A2I178	A0A0A2K2F2	Uncharacterized protein.	Helicase, C-terminal.	0.624
PEX2_009830	PEX2_015370	A0A0A2I178	A0A0A2K4M4	Uncharacterized protein.	Zinc finger, RING-type.	0.691
PEX2_009830	PEX2_015670	A0A0A2I178	A0A0A2K1V3	Uncharacterized protein.	3'-5' exonuclease domain-containing protein.	0.988