39 items (Penicillium expansum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	PEX2_076750	Monooxygenase, FAD-binding. (517 aa)
	PEX2_079560	Uncharacterized protein. (283 aa)
	PEX2_042550	UbiA prenyltransferase family. (332 aa)
	PEX2_104790	Monooxygenase, FAD-binding. (584 aa)
	PEX2_033280	Monooxygenase, FAD-binding. (547 aa)
	PEX2_037810	Monooxygenase, FAD-binding. (594 aa)
	PEX2_016000	Uncharacterized protein. (273 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (247 aa)
	PEX2_081290	Heat shock protein Hsp90, N-terminal. (698 aa)
	PEX2_045670	Monooxygenase, FAD-binding. (680 aa)
	PEX2_109290	Uncharacterized protein. (229 aa)
	PEX2_020960	FMN-binding split barrel-like protein. (302 aa)
	PEX2_082170	Uncharacterized protein. (316 aa)
	PEX2_034340	Monooxygenase, FAD-binding. (613 aa)
	PEX2_033050	Monooxygenase, FAD-binding. (634 aa)
	PEX2_019390	Uncharacterized protein. (333 aa)
	PEX2_073520	Phenol hydroxylase, C-terminal dimerization. (664 aa)
	PEX2_065910	Uncharacterized protein. (265 aa)
	cprA	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (695 aa)
	PEX2_000370	GTP cyclohydrolase I. (326 aa)
	PEX2_030570	Monooxygenase, FAD-binding. (525 aa)
	PEX2_005260	Monooxygenase, FAD-binding. (606 aa)
	PEX2_031560	Uncharacterized protein. (204 aa)
	PEX2_008620	Monooxygenase, FAD-binding. (610 aa)
	PEX2_060580	Monooxygenase, FAD-binding. (666 aa)
	PEX2_022870	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450. (707 aa)
	PEX2_059410	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (418 aa)
	PEX2_109030	Uncharacterized protein. (301 aa)
	PEX2_047610	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (400 aa)
	PEX2_109210	UbiA prenyltransferase family. (316 aa)
	PEX2_047290	Monooxygenase, FAD-binding. (639 aa)
	COQ3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (1024 aa)
	PEX2_052150	Short-chain dehydrogenase/reductase SDR. (253 aa)
	PEX2_028760	Monooxygenase, FAD-binding. (622 aa)
	PEX2_039360	Uncharacterized protein. (268 aa)
	PEX2_019670	Terpenoid synthase; Belongs to the FPP/GGPP synthase family. (447 aa)
	PEX2_010470	Uncharacterized protein. (312 aa)
	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (314 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (511 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COQ3	COQ5	A0A0A2J5P6	A0A0A2LAH2	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.728
COQ3	COQ6	A0A0A2J5P6	A0A0A2L2X3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.737
COQ3	COQ7	A0A0A2J5P6	A0A0A2KAQ9	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	0.914
COQ3	PEX2_005260	A0A0A2J5P6	A0A0A2JK95	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Monooxygenase, FAD-binding.	0.624
COQ3	PEX2_008620	A0A0A2J5P6	A0A0A2JG66	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Monooxygenase, FAD-binding.	0.624
COQ3	PEX2_010470	A0A0A2J5P6	A0A0A2I2Z4	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Uncharacterized protein.	0.624
COQ3	PEX2_016000	A0A0A2J5P6	A0A0A2KBG9	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Uncharacterized protein.	0.624
COQ3	PEX2_019670	A0A0A2J5P6	A0A0A2IAG6	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Terpenoid synthase; Belongs to the FPP/GGPP synthase family.	0.503
COQ3	PEX2_028760	A0A0A2J5P6	A0A0A2INX8	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Monooxygenase, FAD-binding.	0.624
COQ3	PEX2_030570	A0A0A2J5P6	A0A0A2JL25	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Monooxygenase, FAD-binding.	0.624
COQ3	PEX2_031560	A0A0A2J5P6	A0A0A2JIS9	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Uncharacterized protein.	0.624
COQ3	PEX2_033050	A0A0A2J5P6	A0A0A2JZE6	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Monooxygenase, FAD-binding.	0.624
COQ3	PEX2_033280	A0A0A2J5P6	A0A0A2KDW4	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Monooxygenase, FAD-binding.	0.624
COQ3	PEX2_034340	A0A0A2J5P6	A0A0A2JZL3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Monooxygenase, FAD-binding.	0.624
COQ3	PEX2_037810	A0A0A2J5P6	A0A0A2KDG3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Monooxygenase, FAD-binding.	0.624
COQ3	PEX2_039360	A0A0A2J5P6	A0A0A2IEL1	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Uncharacterized protein.	0.624
COQ3	PEX2_042550	A0A0A2J5P6	A0A0A2KFD2	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	UbiA prenyltransferase family.	0.748
COQ3	PEX2_045670	A0A0A2J5P6	A0A0A2K6Q6	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Monooxygenase, FAD-binding.	0.624
COQ3	PEX2_047290	A0A0A2J5P6	A0A0A2J7N6	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Monooxygenase, FAD-binding.	0.624
COQ3	PEX2_052150	A0A0A2J5P6	A0A0A2J3Y9	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Short-chain dehydrogenase/reductase SDR.	0.468